Multi-kilo delivery of AMG 925 featuring a buchwald-hartwig amination and processing with insoluble synthetic intermediates

Organic Process Research and Development

Volumn 19, Issue 3, 2015, Pages 476-485

  Affouard, Caroline ^b   Crockett, Richard D ^a   Diker, Khalid ^b   Farrell, Robert P ^a   Gorins, Gilles ^b   Huckins, John R ^a   Caille, Seb ^a  

^a AMGEN INC   (United States)

^b NORCHIM SAS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; HEAVY METALS; MANUFACTURE; MOLECULES;

ACTIVE PHARMACEUTICAL INGREDIENTS; CREATIVE SOLUTIONS; DRUG CANDIDATES; HEAVY METAL SCAVENGING; HYDROCHLORIDE SALTS; SYNTHETIC INTERMEDIATES; SYNTHETIC ROUTES; TARGET MOLECULE;

SALT REMOVAL;

EID: 84925610421     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op500367p     Document Type: Article

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