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Volumn 95, Issue , 2015, Pages 199-209
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Synthesis of diethyl 4-substituted-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates as a new series of inhibitors against yeast α-glucosidase
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Author keywords
1 4 Dihydropyridine 3 5 dicarboxylates; Anti hyperglycemic activity; Hantzsch reaction; Type II diabetes; Glucosidase inhibition
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Indexed keywords
2 [3,5 BIS(ETHOXYCARBONYL) 2,6 DIMETHYL 1,4 DIHYDRO 4 PYRIDINYL]BENZOIC ACID;
ACARBOSE;
ALPHA GLUCOSIDASE INHIBITOR;
CARBOXYLIC ACID DERIVATIVE;
DIETHYL 2,4,6 TRIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 2,6 DIMETHYL 4 (1H PYRROL 2 YL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 2,6 DIMETHYL 4 (2 THIENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 2,6 DIMETHYL 4 (3 3ENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 2,6 DIMETHYL 4 (3 NITROPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 2,6 DIMETHYL 4 (3 PYRIDINYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 2,6 DIMETHYL 4 (4 METHYLPHENYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 2,6 DIMETHYL 4 (5 METHYL 2 FURYL) 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 2,6 DIMETHYL 4 PHENYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 2,6 DIMETHYL 4 PROPYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 2,6 DIMETHYL 4 [4 (METHYLSULFANYL)PHENYL] 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 4 (2 FLUOROPHENYL) 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 4 (2 FURYL) 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 4 (3 HYDROXYPHENYL) 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 4 (3,4 DIHYDROPHENYL) 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 4 (3,4 DIMETHOXYPHENYL) 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 4 (4 CHLOROPHENYL) 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 4 (4 ETHOXYPHENYL) 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 4 (4 METHOXYPHENYL) 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 4 BUTYL 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 4 ETHYL 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 4 ISOBUTYL 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 4 ISOPROPYL 2,6 DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIETHYL 4 ISOPROPYL 2,6DIETHYL 2,6 DIMETHYL 4 PHENETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE DIMETHYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE;
DIHYDROPYRIDINE DERIVATIVE;
UNCLASSIFIED DRUG;
UNINDEXED DRUG;
ALPHA GLUCOSIDASE;
CARBONATE DEHYDRATASE II;
CARBONATE DEHYDRATASE INHIBITOR;
CARBOXYLIC ACID;
DIETHYL 2,6-DIMETHYL-4-(3-NITROPHENYL)-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLATE;
DIETHYL 2,6-DIMETHYL-4-(4-NITROPHENYL)-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLATE;
GLYCOSIDASE INHIBITOR;
PHOSPHODIESTERASE I;
PHOSPHODIESTERASE INHIBITOR;
PYRIDINE DERIVATIVE;
ARTICLE;
CHEMICAL REACTION;
COMPETITIVE INHIBITION;
CYTOTOXICITY;
DISSOCIATION CONSTANT;
DRUG POTENCY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ENZYME INHIBITION;
HANTZSCH REACTION;
IC50;
KINETICS;
NONHUMAN;
SACCHAROMYCES CEREVISIAE;
ANIMAL;
ANTAGONISTS AND INHIBITORS;
CELL CULTURE;
CELL PROLIFERATION;
CHEMICAL STRUCTURE;
CHEMISTRY;
CYTOLOGY;
DOSE RESPONSE;
DRUG EFFECTS;
ENZYMOLOGY;
FIBROBLAST;
RAT;
STRUCTURE ACTIVITY RELATION;
SYNTHESIS;
ALPHA-GLUCOSIDASES;
ANIMALS;
CARBONIC ANHYDRASE II;
CARBONIC ANHYDRASE INHIBITORS;
CARBOXYLIC ACIDS;
CELL PROLIFERATION;
CELLS, CULTURED;
DOSE-RESPONSE RELATIONSHIP, DRUG;
FIBROBLASTS;
GLYCOSIDE HYDROLASE INHIBITORS;
KINETICS;
MOLECULAR STRUCTURE;
PHOSPHODIESTERASE I;
PHOSPHODIESTERASE INHIBITORS;
PYRIDINES;
RATS;
SACCHAROMYCES CEREVISIAE;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 84925583276
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2015.03.018 Document Type: Article |
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Times cited : (89)
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References (39)
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