Dopamine D4 receptors linked to protein kinase G are required for changes in dopamine release followed by locomotor activity after repeated cocaine administration

Experimental Brain Research

Volumn 233, Issue 5, 2015, Pages 1511-1518

  Oh, Jeong Hwan ^a   Lee, Dong Kun ^a   Shim, Yoon Bo ^a   Ryu, In Soo ^a   Seo, Su Yeon ^a   Kim, Jieun ^a   Yang, Ju Hwan ^a   Cho, Hyun Wook ^b   Choe, Eun Sang ^a  

^a Pusan National University   (South Korea)

^b Sunchon National University   (South Korea)

Author keywords

Dopamine receptor; Drug addiction; Fos related antigen; Protein kinase; Striatum

Indexed keywords

COCAINE; CYCLIC GMP DEPENDENT PROTEIN KINASE; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE 4 RECEPTOR; KT 5823; N [4 (2 CYANOPHENYL) 1 PIPERAZINYLMETHYL] 3 METHYLBENZAMIDE; TRANSCRIPTION FACTOR FOSB; BENZAMIDE DERIVATIVE; CARBAZOLE DERIVATIVE; DOPAMINE RECEPTOR STIMULATING AGENT; DOPAMINE UPTAKE INHIBITOR; ENZYME INHIBITOR; FOSB PROTEIN, RAT; MESSENGER RNA; N-((4-(2-CYANOPHENYL)-1-PIPERAZINYL)METHYL)-3-METHYLBENZAMIDE; NEURONAL NITRIC OXIDE SYNTHASE; PIPERAZINE DERIVATIVE; PROTEIN C FOS; TYROSINE 3 MONOOXYGENASE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAUDATE NUCLEUS; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; EXPOSURE; IMMUNOREACTIVITY; LOCOMOTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; ANALYSIS OF VARIANCE; ANIMAL; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOTOR ACTIVITY; SPRAGUE DAWLEY RAT;

ANALYSIS OF VARIANCE; ANIMALS; BENZAMIDES; CARBAZOLES; COCAINE; CYCLIC GMP-DEPENDENT PROTEIN KINASES; DOPAMINE; DOPAMINE AGONISTS; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; MALE; MOTOR ACTIVITY; NITRIC OXIDE SYNTHASE TYPE I; PIPERAZINES; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D4; RNA, MESSENGER; TYROSINE 3-MONOOXYGENASE;

EID: 84925541407     PISSN: 00144819     EISSN: 14321106     Source Type: Journal    
DOI: 10.1007/s00221-015-4228-6     Document Type: Article

References (21)

1. Abdelwahab AA, Lee HM, Shim YB (2009) Selective determination of dopamine with a cibacron blue/poly-1,5-diaminonaphthalene composite film. Anal Chim Acta 650:247–253
2. Beaulieu JM, Gainetdinov RR (2011) The physiology, signaling, and pharmacology of dopamine receptors. Pharmacol Rev 63:182–217
3. Chien WL, Liang KC, Teng CM, Kuo SC, Lee FY, Fu WM (2005) Enhancement of learning behaviour by a potent nitric oxide-guanylate cyclase activator YC-1. Eur J Neurosci 21:1679–1688
4. Choe ES, Parelkar NK, Kim JY, Cho HW, Kang HS, Mao L, Wang JQ (2004) The protein phosphatase 1/2A inhibitor okadaic acid increases CREB and Elk-1 phosphorylation and c-fos expression in the rat striatum in vivo. J Neurochem 89:383–390
5. Collins SL, Kantak KM (2002) Neuronal nitric oxide synthase inhibition decreases cocaine self-administration behavior in rats. Psychopharmacology 159:361–369
6. Domek-Łopacińska K, Strosznajder JB (2005) Cyclic GMP metabolism and its role in brain physiology. J Physiol Pharmacol 56(Suppl 2):15–34
7. Hsieh GC, Hollingsworth PR, Martino B, Chang R, Terranova MA, O’Neill AB, Lynch JJ, Moreland RB, Donnelly-Roberts DL, Kolasa T, Mikusa JP, McVey JM, Marsh KC, Sullivan JP, Brioni JD (2004) Central mechanisms regulating penile erection in conscious rats: the dopaminergic systems related to the proerectile effect of apomorphine. J Pharmacol Exp Ther 308:330–338
8. Jones SR, Garris PA, Wightman RM (1995) Different effects of cocaine and nomifensine on dopamine uptake in the caudate-putamen and nucleus accumbens. J Pharmacol Exp Ther 274:396–403
9. Jouvert P, Revel MO, Lazaris A, Aunis D, Langley K, Zwiller J (2004) Activation of the cGMP pathway in dopaminergic structures reduces cocaine-induced EGR-1 expression and locomotor activity. J Neurosci 24:10716–10725
10. Lee DK, Koh WC, Shim YB, Shim I, Choe ES (2010) Repeated cocaine administration increases nitric oxide efflux in the rat dorsal striatum. Psychopharmacology 208:245–256
11. Lee DK, Oh JH, Shim YB, Choe ES (2013a) Protein kinase G regulates dopamine release, ΔFosB expression, and locomotor activity after repeated cocaine administration: involvement of dopamine D2 receptors. Neurochem Res 38:1424–1433
12. Lee DK, Oh JH, Yang JH, Youn B, Shim YB, Shim I, Wang JQ, Choe ES (2013b) Protein kinase G linked to dopamine D3 receptors in the dorsal striatum controls dopamine release, ΔFosB expression and locomotor activity after repeated cocaine administration. Neurosci Lett 541:120–125
13. Liu XY, Chu XP, Mao LM, Wang M, Lan HX, Li MH, Zhang GC, Parelkar NK, Fibuch EE, Haines M, Neve KA, Liu F, Xiong ZG, Wang JQ (2006) Modulation of D2R-NR2B interactions in response to cocaine. Neuron 52:897–909
14. Maina FK, Mathews TA (2010) A functional fast scan cyclic voltammetry assay to characterize dopamine D2 and D3 autoreceptors in the mouse striatum. ACS Chem Neurosci 1:450–462
15. Ota KT, Monsey MS, Wu MS, Schafe GE (2010) Synaptic plasticity and NO–cGMP–PKG signaling regulate pre- and postsynaptic alterations at rat lateral amygdala synapses following fear conditioning. PLoS ONE 5:e11236
16. Rivera A, Cuéllar B, Girón FJ, Grandy DK, de la Calle A, Moratalla R (2002) Dopamine D4 receptors are heterogeneously distributed in the striosomes/matrix compartments of the striatum. J Neurochem 80:219–229
17. Rubinstein M, Phillips TJ, Bunzow JR, Falzone TL, Dziewczapolski G, Zhang G, Fang Y, Larson JL, McDougall JA, Chester JA, Saez C, Pugsley TA, Gershanik O, Low MJ, Grandy DK (1997) Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine. Cell 90:991–1001
18. Sammut S, Threlfell S, West AR (2010) Nitric oxide-soluble guanylyl cyclase signaling regulates corticostriatal transmission and short-term synaptic plasticity of striatal projection neurons recorded in vivo. Neuropharmacology 58:624–631
19. Venton BJ, Seipel AT, Phillips PE, Wetsel WC, Gitler D, Greengard P, Augustine GJ, Wightman RM (2006) Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool. J Neurosci 26:3206–3209
20. Volkow ND, Wang GJ, Telang F, Fowler JS, Logan J, Childress AR, Jayne M, Ma Y, Wong C (2006) Cocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction. J Neurosci 26:6583–6588
21. Wise RA (2008) Dopamine and reward: the anhedonia hypothesis 30 years on. Neurotox Res 14:169–183