Serum levels of fetuin A are increased in women with gestational diabetes mellitus

Archives of Gynecology and Obstetrics

Volumn 291, Issue 4, 2015, Pages 933-937

  Iyidir, Ozlem Turhan ^a   Degertekin, Ceyla Konca ^a   Yilmaz, Banu Aktas ^a   Altinova, Alev E ^a   Toruner, Fusun B ^a   Bozkurt, Nuray ^a   Ayvaz, Goksun ^a   Akturk, Mujde ^a  

^a GAZI UNIVERSITY   (Turkey)

Author keywords

Fetuin A; Gestational diabetes mellitus; HbA1c; Lipids

Indexed keywords

CHOLESTEROL; FETUIN A; HEMOGLOBIN A1C; TRIACYLGLYCEROL; GLYCOSYLATED HEMOGLOBIN; INSULIN;

ADULT; ARTICLE; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GESTATIONAL AGE; HEMOGLOBIN BLOOD LEVEL; HUMAN; PATHOGENESIS; PREGNANCY DIABETES MELLITUS; PREGNANT WOMAN; PROTEIN BLOOD LEVEL; PUERPERIUM; TRIACYLGLYCEROL BLOOD LEVEL; BLOOD; BODY MASS; CASE CONTROL STUDY; DELIVERY; INSULIN RESISTANCE; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOPHYSIOLOGY; PREGNANCY;

ADULT; ALPHA-2-HS-GLYCOPROTEIN; BODY MASS INDEX; CASE-CONTROL STUDIES; DELIVERY, OBSTETRIC; DIABETES MELLITUS, TYPE 2; DIABETES, GESTATIONAL; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INSULIN; INSULIN RESISTANCE; POSTPARTUM PERIOD; PREGNANCY;

EID: 84925511399     PISSN: 09320067     EISSN: 14320711     Source Type: Journal    
DOI: 10.1007/s00404-014-3490-3     Document Type: Article

References (27)

1. Arnaud P, Miribel L, Emerson DL (1988) Alpha 2-HS glycoprotein. Methods Enzymol 163:431–441
2. Mori K, Emoto M, Inaba M (2011) Fetuin-A: a multifunctional protein. Recent Pat Endocr Metab Immune Drug Discov 5(2):124–146
3. Stefan N, Hennige AM, Staiger H, Machann J, Schick F, Krober SM, Machicao F, Fritsche A, Haring HU (2006) Alpha2-Heremans-Schmid glycoprotein/fetuin-A is associated with insulin resistance and fat accumulation in the liver in humans. Diabetes Care 29(4):853–857
4. Enli Y, Fenkci SM, Fenkci V, Oztekin O (2013) Serum Fetuin-A levels, insulin resistance and oxidative stress in women with polycystic ovary syndrome. Gynecol Endocrinol 29(12):1036–1039. doi:10.3109/09513590.2013.829442
5. Ou HY, Yang YC, Wu HT, Wu JS, Lu FH, Chang CJ (2011) Serum fetuin-A concentrations are elevated in subjects with impaired glucose tolerance and newly diagnosed type 2 diabetes. Clin Endocrinol 75(4):450–455. doi:10.1111/j.1365-2265.2011.04070.x
6. Singh M, Sharma PK, Garg VK, Mondal SC, Singh AK, Kumar N (2012) Role of fetuin-A in atherosclerosis associated with diabetic patients. J Pharm Pharmacol 64(12):1703–1708. doi:10.1111/j.2042-7158.2012.01561.x
7. Song A, Xu M, Bi Y, Xu Y, Huang Y, Li M, Wang T, Wu Y, Liu Y, Li X, Chen Y, Wang W, Ning G (2011) Serum fetuin-A associates with type 2 diabetes and insulin resistance in Chinese adults. PLoS One 6(4):e19228. doi:10.1371/journal.pone.0019228
8. Sun Q, Cornelis MC, Manson JE, Hu FB (2013) Plasma levels of fetuin-A and hepatic enzymes and risk of type 2 diabetes in women in the US. Diabetes 62(1):49–55. doi:10.2337/db12-0372
9. Mathews ST, Chellam N, Srinivas PR, Cintron VJ, Leon MA, Goustin AS, Grunberger G (2000) Alpha2-HSG, a specific inhibitor of insulin receptor autophosphorylation, interacts with the insulin receptor. Mol Cell Endocrinol 164(1–2):87–98
10. Catalano PM (2014) Trying to understand gestational diabetes. Diabet Med 31(3):273–281. doi:10.1111/dme.12381
11. Huopio H, Cederberg H, Vangipurapu J, Hakkarainen H, Paakkonen M, Kuulasmaa T, Heinonen S, Laakso M (2013) Association of risk variants for type 2 diabetes and hyperglycemia with gestational diabetes. Eur J Endocrinol 169(3):291–297. doi:10.1530/EJE-13-0286
12. Kim C, Newton KM, Knopp RH (2002) Gestational diabetes and the incidence of type 2 diabetes: a systematic review. Diabetes Care 25(10):1862–1868
13. Barbour LA, McCurdy CE, Hernandez TL, Friedman JE (2011) Chronically increased S6K1 is associated with impaired IRS1 signaling in skeletal muscle of GDM women with impaired glucose tolerance postpartum. J Clin Endocrinol Meta 96(5):1431–1441. doi:10.1210/jc.2010-2116
14. Kalabay L, Cseh K, Pajor A, Baranyi E, Csakany GM, Melczer Z, Speer G, Kovacs M, Siller G, Karadi I, Winkler G (2002) Correlation of maternal serum fetuin/alpha2-HS-glycoprotein concentration with maternal insulin resistance and anthropometric parameters of neonates in normal pregnancy and gestational diabetes. Eur J Endocrinol 147(2):243–248
15. Farhan S, Handisurya A, Todoric J, Tura A, Pacini G, Wagner O, Klein K, Jarai R, Huber K, Kautzky-Willer A (2012) Fetuin-A characteristics during and after pregnancy: result from a case control pilot study. Int J Endocrinol 2012:896736. doi:10.1155/2012/896736
16. Coustan DR, Carpenter MW (1998) The diagnosis of gestational diabetes. Diabetes Care 21(Suppl 2):B5–B8
17. Friedewald WT, Levy RI, Fredrickson DS (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18(6):499–502
18. Denecke B, Graber S, Schafer C, Heiss A, Woltje M, Jahnen-Dechent W (2003) Tissue distribution and activity testing suggest a similar but not identical function of fetuin-B and fetuin-A. Biochem J 376(Pt 1):135–145. doi:10.1042/BJ20030676
19. Olivier E, Soury E, Ruminy P, Husson A, Parmentier F, Daveau M, Salier JP (2000) Fetuin-B, a second member of the fetuin family in mammals. Biochem J 350(Pt 2):589–597
20. Briana DD, Boutsikou M, Gourgiotis D, Boutsikou T, Baka S, Marmarinos A, Hassiakos D, Malamitsi-Puchner A (2008) Serum fetuin-A/alpha2-HS-glycoprotein in human pregnancies with normal and restricted fetal growth. J Matern Fetal Neonatal Med 21(11):826–830. doi:10.1080/14767050802326255
21. Gunduz FO, Yildirmak ST, Temizel M, Faki Y, Cakmak M, Durmuscan M, Sezgin F (2011) Serum visfatin and fetuin-a levels and glycemic control in patients with obese type 2 diabetes mellitus. Diabetes Metab J 35(5):523–528. doi:10.4093/dmj.2011.35.5.523
22. Erdmann J, Salmhofer H, Knauss A, Mayr M, Wagenpfeil S, Sypchenko O, Luppa P, Schusdziarra V (2012) Relationship of fetuin-A levels to weight-dependent insulin resistance and type 2 diabetes mellitus. Regul Pept 178(1–3):6–10. doi:10.1016/j.regpep.2012.02.004
23. Liu Y, Xu M, Xu Y, Li M, Wang T, Chen Y, Bi Y (2012) Positive correlation between chronic hyperglycemia and serum fetuin-A levels in middle-aged and elderly Chinese. J Diabetes 4(4):351–358. doi:10.1111/1753-0407.12000
24. Ozyazgan S, Karaoglu K, Kurt A, Altinok A, Konukoglu D, Osar Siva Z, Andican G (2013) Effects of omega-3 polyunsaturated fatty acid supplementation on serum fetuin-A levels in type 2 diabetic patients. Minerva Med 104(3):287–293
25. Jung CH, Kim BY, Kim CH, Kang SK, Jung SH, Mok JO (2013) Associations of serum fetuin-A levels with insulin resistance and vascular complications in patients with type 2 diabetes. Diab Vasc Dis Res 10(5):459–467. doi:10.1177/1479164113490766
26. Stefan N, Haring HU (2013) Circulating fetuin-A and free fatty acids interact to predict insulin resistance in humans. Nat Med 19(4):394–395. doi:10.1038/nm.3116
27. Pal D, Dasgupta S, Kundu R, Maitra S, Das G, Mukhopadhyay S, Ray S, Majumdar SS, Bhattacharya S (2012) Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance. Nat Med 18(8):1279–1285. doi:10.1038/nm.2851