Longitudinal prevalence of potentially inappropriate medicines and potential prescribing omissions in a cohort of community-dwelling older people

European Journal of Clinical Pharmacology

Volumn 71, Issue 4, 2015, Pages 473-482

  Moriarty, Frank ^a   Bennett, Kathleen ^b   Fahey, Tom ^a   Kenny, Rose Anne ^c   Cahir, Caitriona ^b  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b ST JAMES S HOSPITAL   (Ireland)

^c TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

ACOVE indicators; Beers criteria; Cohort; Potentially inappropriate prescribing; START; STOPP

Indexed keywords

ACETYLSALICYLIC ACID; ANTICONVULSIVE AGENT; ANTIHYPERTENSIVE AGENT; BENZODIAZEPINE; BENZODIAZEPINE DERIVATIVE; BISPHOSPHONIC ACID DERIVATIVE; BRONCHODILATING AGENT; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; CHOLINERGIC RECEPTOR BLOCKING AGENT; CORTICOSTEROID; CYCLOOXYGENASE 2 INHIBITOR; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HISTAMINE H2 RECEPTOR ANTAGONIST; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYPNOTIC AGENT; IRON; LAXATIVE; LOOP DIURETIC AGENT; METOCLOPRAMIDE; MISOPROSTOL; NEUROLEPTIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; PROTON PUMP INHIBITOR; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG; VITAMIN D; WARFARIN;

AGED; ARTICLE; COHORT ANALYSIS; FEMALE; GERIATRIC PATIENT; HUMAN; INAPPROPRIATE PRESCRIBING; INTERVIEW; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; OSTEOPOROSIS; PREVALENCE; PRIMARY PREVENTION; PRIORITY JOURNAL; SCREEENING TOOL TO ALERT DOCTORS TO RIGHT TREATMENT; SCREENING; SCREENING TEST; SCREENING TOOL FOR OLDER PERSONS PRESCRIPTIONS; CLINICAL PRACTICE; DEMOGRAPHY; MEDICAL ERROR; PRESCRIPTION; PROSPECTIVE STUDY; STATISTICS AND NUMERICAL DATA;

AGED; DRUG PRESCRIPTIONS; FEMALE; HUMANS; INAPPROPRIATE PRESCRIBING; LONGITUDINAL STUDIES; MALE; MEDICAL ERRORS; PRACTICE PATTERNS, PHYSICIANS'; PREVALENCE; PROSPECTIVE STUDIES; RESIDENCE CHARACTERISTICS;

EID: 84925508355     PISSN: 00316970     EISSN: 14321041     Source Type: Journal    
DOI: 10.1007/s00228-015-1815-1     Document Type: Article

References (36)

1. Avorn J (2005) Powerful medicines: the benefits, risks, and costs of prescription drugs. Random House, New York
2. Mallet L, Spinewine A, Huang A (2007) The challenge of managing drug interactions in elderly people. Lancet 370:185-191
3. Marengoni A, Angleman S, Melis R et al (2011) Aging with multimorbidity: a systematic review of the literature. Ageing Res Rev 10:430-439. doi: 10.1016/j.arr.2011.03.003
4. Fulton MM, Riley Allen E (2005) Polypharmacy in the elderly: a literature review. J Am Acad Nurse Pract 17:123-132. doi: 10.1111/j.1041-2972.2005.0020.x
5. O'Connor MN, Gallagher P, O'Mahony D (2012) Inappropriate prescribing. Criteria, detection and prevention. Drugs Aging 29:437-452
6. Beers M, Ouslander J, Rollingher I et al (1991) Explicit criteria for determining inappropriate medication use in nursing home residents. Arch Intern Med 151:1825-1832
7. American Geriatrics Society (2012) Beers Criteria Update Expert Panel (2012) American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults. J Am Geriatr Soc 60:616-631. doi: 10.1111/j.1532-5415.2012.03923.x
8. Jano E, Aparasu RR (2007) Healthcare outcomes associated with Beers' criteria: a systematic review. Ann Pharmacother 41:438-447. doi: 10.1345/aph.1H473
9. Gallagher P, Ryan C, Byrne S et al (2008) STOPP (Screening Tool of Older Person's Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment). Consensus validation. Int J Clin Pharmacol Ther 46:72-83
10. Gallagher P, Baeyens J-P, Topinkova E et al (2009) Inter-rater reliability of STOPP (Screening Tool of Older Persons' Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment) criteria amongst physicians in six European countries. Age Ageing 38:603-606. doi: 10.1093/ageing/afp097
11. Ryan C, O'Mahony D, Byrne S (2009) Application of STOPP and START criteria: interrater reliability among pharmacists. Ann Pharmacother 43:1239-1244. doi: 10.1345/aph.1M157
12. Hill-Taylor B, Sketris I, Hayden J et al (2013) Application of the STOPP/START criteria: a systematic review of the prevalence of potentially inappropriate prescribing in older adults, and evidence of clinical, humanistic and economic impact. J Clin Pharm Ther 38:360-372. doi: 10.1111/jcpt.12059
13. Wenger N, Roth C, Shekelle P (2007) Introduction to the Assessing Care of Vulnerable Elders-3 quality indicator measurement set. J Am Geriatr Soc 55:S247-S252
14. San-José A, Agustí A, Vidal X et al (2014) An inter-rater reliability study of the prescribing indicated medications quality indicators of the Assessing Care Of Vulnerable Elders (ACOVE) 3 criteria as a potentially inappropriate prescribing tool. Arch Gerontol Geriatr 58:460-464. doi: 10.1016/j.archger.2013.12.006
15. Pileggi C, Manuti B, Costantino R et al (2014) Quality of care in one Italian nursing home measured by ACOVE process indicators. PLoS ONE 9:e93064. doi: 10.1371/journal.pone.0093064
16. Ryan C, O'Mahony D, Kennedy J et al (2009) Potentially inappropriate prescribing in an Irish elderly population in primary care. Br J Clin Pharmacol 68:936-947. doi: 10.1111/j.1365-2125.2009.03531.x
17. Conejos Miquel M, Sánchez Cuervo M, Delgado Silveira E et al (2010) Potentially inappropriate drug prescription in older subjects across health care settings. Eur Geriatr Med 1:9-14. doi: 10.1016/j.eurger.2009.12.002
18. Pyszka LL, Seys Ranola TM, Milhans SM (2010) Identification of inappropriate prescribing in geriatrics at a Veterans Affairs hospital using STOPP/START screening tools. Consult Pharm 25:365-373. doi: 10.4140/TCP.n.2010.365
19. Gallagher PF, O'Connor MN, O'Mahony D (2011) Prevention of potentially inappropriate prescribing for elderly patients: a randomized controlled trial using STOPP/START criteria. Clin Pharmacol Ther 89:845-854. doi: 10.1038/clpt.2011.44
20. Gallagher P, Lang P, Cherubini A et al (2011) Prevalence of potentially inappropriate prescribing in an acutely ill population of older patients admitted to six European hospitals. Eur J Clin Pharmacol 67:1175-1188. doi: 10.1007/s00228-011-1061-0
21. Galvin R, Moriarty F, Cousins G et al (2014) Prevalence of potentially inappropriate prescribing and prescribing omissions in older Irish adults: findings from The Irish LongituDinal Study on Ageing study (TILDA). Eur J Clin Pharmacol 70:599-606. doi: 10.1007/s00228-014-1651-8
22. Richardson K, Kenny RA, Peklar J, Bennett K (2013) Agreement between patient interview data on prescription medication use and pharmacy records in those aged older than 50 years varied by therapeutic group and reporting of indicated health conditions. J Clin Epidemiol 66:1308-1316. doi: 10.1016/j.jclinepi.2013.02.016
23. Zeger SL, Liang KY, Albert PS (1988) Models for longitudinal data: a generalized estimating equation approach. Biometrics 44:1049-1060
24. Aparasu RR, Mort JR (2000) Inappropriate prescribing for the elderly: Beers criteria-based review. Ann Pharmacother 34:338-346
25. O'Sullivan DP, O'Mahony D, Parsons C et al (2013) A prevalence study of potentially inappropriate prescribing in Irish long-term care residents. Drugs Aging 30:39-49. doi: 10.1007/s40266-012-0039-7
26. Elseviers MM, Vander Stichele RR, Van Bortel L (2013) Quality of prescribing in Belgian nursing homes: an electronic assessment of the medication chart. Int J Qual Health Care 26:93-99. doi: 10.1093/intqhc/mzt089
27. Blanco-Reina E, Ariza-Zafra G, Ocaña-Riola R et al (2015) Optimizing elderly pharmacotherapy: polypharmacy vs. undertreatment. Are these two concepts related? Eur J Clin Pharmacol 71:199-207. doi: 10.1007/s00228-014-1780-0
28. Zimmermann T, Kaduszkiewicz H, van den Bussche H et al (2013) Potentially inappropriate medication in elderly primary care patients: a retrospective, longitudinal analysis. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 56:941-949. doi: 10.1007/s00103-013-1767-5
29. Price SD, Holman CDJ, Sanfilippo FM, Emery JD (2014) Are older Western Australians exposed to potentially inappropriate medications according to the Beers Criteria? A 13-year prevalence study. Aust J Ageing 33:E39-E48. doi: 10.1111/ajag.12136
30. Lapi F, Pozzi C, Mazzaglia G, Ungar A (2009) Epidemiology of suboptimal prescribing in older, community dwellers. Drugs Aging 26:1029-1039
31. Department of Health and Children (2008) Tackling chronic disease: a policy framework for the management of chronic diseases. Dublin
32. Perk J, De Backer G, Gohlke H et al (2012) European Guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice. Eur Heart J 33:1635-1701. doi: 10.1093/eurheartj/ehs092
33. Vandvik PO, Lincoff AM, Gore JM et al (2012) Primary and secondary prevention of cardiovascular disease: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 141:e637S-e668S. doi: 10.1378/chest. 11-2306
34. Cahir C, Fahey T, Tilson L et al (2012) Proton pump inhibitors: potential cost reductions by applying prescribing guidelines. BMC Health Serv Res 12:408. doi: 10.1186/1472-6963-12-408
35. Health Services Executive Medicines Management Programme [Internet]. http://www.hse.ie/yourmedicines. Accessed 1 Jul 2014
36. Wilhelm SM, Rjater RG, Kale-Pradhan PB (2013) Perils and pitfalls of long-term effects of proton pump inhibitors. Expert Rev Clin Pharmacol 6:443-451. doi: 10.1586/17512433.2013.811206