메뉴 건너뛰기




Volumn 55, Issue 3, 2015, Pages 706-714

Increased Expression of Protease-Activated Receptor 2 and 4 Within Dorsal Root Ganglia in a Rat Model of Bone Cancer Pain

Author keywords

Bone cancer pain; Dorsal root ganglia; Mechanical allodynia; PAR2; PAR4; Spontaneous nocifensive behavior; Thermal hyperalgesia

Indexed keywords

MESSENGER RNA; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 4; PROTEASE-ACTIVATED RECEPTOR 4; THROMBIN RECEPTOR;

EID: 84925497044     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-014-0409-1     Document Type: Article
Times cited : (20)

References (40)
  • 1
    • 37349118143 scopus 로고    scopus 로고
    • Intrathecal administration of proteinase-activated receptor-2 agonists produces hyperalgesia by exciting the cell bodies of primary sensory neurons
    • COI: 1:CAS:528:DC%2BD1cXhsF2hug%3D%3D, PID: 17921188
    • Alier KA, Endicott JA, Stemkowski PL, Cenac N, Cellars L, Chapman K, Andrade-Gordon P, Vergnolle N, Smith PA (2008) Intrathecal administration of proteinase-activated receptor-2 agonists produces hyperalgesia by exciting the cell bodies of primary sensory neurons. J Pharmacol Exp Ther 324(1):224–233
    • (2008) J Pharmacol Exp Ther , vol.324 , Issue.1 , pp. 224-233
    • Alier, K.A.1    Endicott, J.A.2    Stemkowski, P.L.3    Cenac, N.4    Cellars, L.5    Chapman, K.6    Andrade-Gordon, P.7    Vergnolle, N.8    Smith, P.A.9
  • 3
    • 84925468946 scopus 로고    scopus 로고
    • Protease-activated receptor 2 signalling pathways: a role in pain processing
    • Bao Y. Hou W. Hua B. 2013a. Protease-activated receptor 2 signalling pathways: a role in pain processing. Expert opinion on therapeutic targets
    • (2013) Expert opinion on therapeutic targets
    • Hua, B.Y.H.W.1
  • 4
    • 84899083039 scopus 로고    scopus 로고
    • Involvement of protease-activated receptor 2 in nociceptive behavior in a rat model of bone cancer
    • Bao Y. Hua B. Hou W. Shi Z. Li W. Li C. Chen C. Liu R. Qin Y. 2013b. Involvement of protease-activated receptor 2 in nociceptive behavior in a rat model of bone cancer. J Mol Neurosci, 52:566–576
    • (2013) J Mol Neurosci , vol.52 , pp. 566-576
  • 5
    • 0242410340 scopus 로고    scopus 로고
    • Cancer pain
    • COI: 1:CAS:528:DC%2BD3sXptVWrtb8%3D
    • Bruera E, Kim HN (2003) Cancer pain. JAMA-J Am Med Assoc 290(18):2476–2479
    • (2003) JAMA-J Am Med Assoc , vol.290 , Issue.18 , pp. 2476-2479
    • Bruera, E.1    Kim, H.N.2
  • 6
    • 0025581591 scopus 로고
    • Cancer pain relief and palliative care. Report of a WHO expert committee
    • World Health Organization (1990) Cancer pain relief and palliative care. Report of a WHO expert committee. World Health Organ Tech Rep Ser 804:1–75
    • (1990) World Health Organ Tech Rep Ser , vol.804 , pp. 1-75
    • World Health Organization1
  • 7
    • 84876695037 scopus 로고    scopus 로고
    • Capsaicin up-regulates protease-activated receptor-4 mRNA and protein in primary cultured dorsal root ganglion neurons
    • PID: 23274964
    • Chen D, Wang Z, Zhang Z, Zhang R, Yu L (2013) Capsaicin up-regulates protease-activated receptor-4 mRNA and protein in primary cultured dorsal root ganglion neurons. Cell Mol Neurobiol 33(3):337–346
    • (2013) Cell Mol Neurobiol , vol.33 , Issue.3 , pp. 337-346
    • Chen, D.1    Wang, Z.2    Zhang, Z.3    Zhang, R.4    Yu, L.5
  • 8
    • 33750726077 scopus 로고    scopus 로고
    • Clinical features of metastatic bone disease and risk of skeletal morbidity
    • PID: 17062708
    • Coleman RE (2006) Clinical features of metastatic bone disease and risk of skeletal morbidity. Clin Cancer Res 12(20 Pt 2):6243s–6249s
    • (2006) Clin Cancer Res , vol.12 , Issue.20 , pp. 6243s-6249s
    • Coleman, R.E.1
  • 9
    • 43649093122 scopus 로고    scopus 로고
    • Challenges in cancer pain management–bone pain
    • COI: 1:STN:280:DC%2BD1cvktVWitQ%3D%3D, PID: 18439817
    • Colvin L, Fallon M (2008) Challenges in cancer pain management–bone pain. Eur J Cancer 44(8):1083–1090
    • (2008) Eur J Cancer , vol.44 , Issue.8 , pp. 1083-1090
    • Colvin, L.1    Fallon, M.2
  • 10
    • 0036262319 scopus 로고    scopus 로고
    • International union of pharmacology XXVIII. Proteinase-activated receptors
    • COI: 1:CAS:528:DC%2BD38XltVOiurg%3D, PID: 12037136
    • Hollenberg MD, Compton SJ (2002) International union of pharmacology XXVIII. Proteinase-activated receptors. Pharmacol Rev 54(2):203–217
    • (2002) Pharmacol Rev , vol.54 , Issue.2 , pp. 203-217
    • Hollenberg, M.D.1    Compton, S.J.2
  • 11
    • 7544230083 scopus 로고    scopus 로고
    • Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides as probes for receptor function and as inflammatory agonists in vivo
    • COI: 1:CAS:528:DC%2BD2cXpsFCnsrY%3D, PID: 15451771
    • Hollenberg MD, Saifeddine M, Sandhu S, Houle S, Vergnolle N (2004) Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides as probes for receptor function and as inflammatory agonists in vivo. Br J Pharmacol 143(4):443–454
    • (2004) Br J Pharmacol , vol.143 , Issue.4 , pp. 443-454
    • Hollenberg, M.D.1    Saifeddine, M.2    Sandhu, S.3    Houle, S.4    Vergnolle, N.5
  • 13
    • 27644557524 scopus 로고    scopus 로고
    • Neutrophils and the kallikrein-kinin system in proteinase-activated receptor 4-mediated inflammation in rodents
    • COI: 1:CAS:528:DC%2BD2MXhtFKht7jP, PID: 16100525
    • Houle S, Papez MD, Ferazzini M, Hollenberg MD, Vergnolle N (2005) Neutrophils and the kallikrein-kinin system in proteinase-activated receptor 4-mediated inflammation in rodents. Br J Pharmacol 146(5):670–678
    • (2005) Br J Pharmacol , vol.146 , Issue.5 , pp. 670-678
    • Houle, S.1    Papez, M.D.2    Ferazzini, M.3    Hollenberg, M.D.4    Vergnolle, N.5
  • 15
    • 0032483456 scopus 로고    scopus 로고
    • Gene and locus structure and chromosomal localization of the protease-activated receptor gene family
    • COI: 1:CAS:528:DyaK1cXlvFaksb8%3D, PID: 9722561
    • Kahn ML, Hammes SR, Botka C, Coughlin SR (1998) Gene and locus structure and chromosomal localization of the protease-activated receptor gene family. J Biol Chem 273(36):23290–23296
    • (1998) J Biol Chem , vol.273 , Issue.36 , pp. 23290-23296
    • Kahn, M.L.1    Hammes, S.R.2    Botka, C.3    Coughlin, S.R.4
  • 16
    • 77951765901 scopus 로고    scopus 로고
    • Serine proteases and protease-activated receptor 2-dependent allodynia: a novel cancer pain pathway
    • COI: 1:CAS:528:DC%2BC3cXlt1Smtrw%3D, PID: 20189717
    • Lam DK, Schmidt BL (2010) Serine proteases and protease-activated receptor 2-dependent allodynia: a novel cancer pain pathway. Pain 149(2):263–272
    • (2010) Pain , vol.149 , Issue.2 , pp. 263-272
    • Lam, D.K.1    Schmidt, B.L.2
  • 17
    • 84867245616 scopus 로고    scopus 로고
    • Novel animal models of acute and chronic cancer pain: a pivotal role for PAR2
    • COI: 1:CAS:528:DC%2BC38XhsFGlsb7M, PID: 23055487
    • Lam DK, Dang D, Zhang J, Dolan JC, Schmidt BL (2012) Novel animal models of acute and chronic cancer pain: a pivotal role for PAR2. J Neurosci 32(41):14178–14183
    • (2012) J Neurosci , vol.32 , Issue.41 , pp. 14178-14183
    • Lam, D.K.1    Dang, D.2    Zhang, J.3    Dolan, J.C.4    Schmidt, B.L.5
  • 18
    • 0036196408 scopus 로고    scopus 로고
    • Phenotype and function of somatic primary afferent nociceptive neurones with C-, Adelta- or Aalpha/beta-fibres
    • COI: 1:STN:280:DC%2BD387ktFOgsg%3D%3D, PID: 11856969
    • Lawson SN (2002) Phenotype and function of somatic primary afferent nociceptive neurones with C-, Adelta- or Aalpha/beta-fibres. Exp Physiol 87(2):239–244
    • (2002) Exp Physiol , vol.87 , Issue.2 , pp. 239-244
    • Lawson, S.N.1
  • 19
    • 84898911895 scopus 로고    scopus 로고
    • Protease-activated receptor 2 in dorsal root ganglion contributes to peripheral sensitization of bone cancer pain. Eur J Pain
    • Liu S. Liu YP. Yue DM. Liu GJ. 2013. Protease-activated receptor 2 in dorsal root ganglion contributes to peripheral sensitization of bone cancer pain. Eur J Pain. doi: 10.1002/j.1532-2149.2013.00372.x.
    • (2013) doi: 10.1002/j.1532-2149.2013.00372.x
  • 21
    • 0036515869 scopus 로고    scopus 로고
    • Molecular mechanisms of cancer pain
    • COI: 1:CAS:528:DC%2BD38Xis1KktLo%3D, PID: 11990856
    • Mantyh PW, Clohisy DR, Koltzenburg M, Hunt SP (2002) Molecular mechanisms of cancer pain. Nat Rev Cancer 2(3):201–209
    • (2002) Nat Rev Cancer , vol.2 , Issue.3 , pp. 201-209
    • Mantyh, P.W.1    Clohisy, D.R.2    Koltzenburg, M.3    Hunt, S.P.4
  • 22
    • 33744522805 scopus 로고    scopus 로고
    • A rat model of bone cancer pain induced by intra-tibia inoculation of walker 256 mammary gland carcinoma cells
    • COI: 1:CAS:528:DC%2BD28Xltl2hu7Y%3D, PID: 16725112
    • Mao-Ying QL, Zhao J, Dong ZQ, Wang J, Yu J, Yan MF, Zhang YQ, Wu GC, Wang YQ (2006) A rat model of bone cancer pain induced by intra-tibia inoculation of walker 256 mammary gland carcinoma cells. Biochem Biophys Res Commun 345(4):1292–1298
    • (2006) Biochem Biophys Res Commun , vol.345 , Issue.4 , pp. 1292-1298
    • Mao-Ying, Q.L.1    Zhao, J.2    Dong, Z.Q.3    Wang, J.4    Yu, J.5    Yan, M.F.6    Zhang, Y.Q.7    Wu, G.C.8    Wang, Y.Q.9
  • 23
    • 61649090828 scopus 로고    scopus 로고
    • Triggering of proteinase-activated receptor 4 leads to joint pain and inflammation in mice
    • COI: 1:CAS:528:DC%2BD1MXktVGmsLs%3D, PID: 19248120
    • McDougall JJ, Zhang C, Cellars L, Joubert E, Dixon CM, Vergnolle N (2009) Triggering of proteinase-activated receptor 4 leads to joint pain and inflammation in mice. Arthritis Rheum 60(3):728–737
    • (2009) Arthritis Rheum , vol.60 , Issue.3 , pp. 728-737
    • McDougall, J.J.1    Zhang, C.2    Cellars, L.3    Joubert, E.4    Dixon, C.M.5    Vergnolle, N.6
  • 25
    • 0038816463 scopus 로고    scopus 로고
    • Initial thermal heat hypoalgesia and delayed hyperalgesia in a murine model of bone cancer pain
    • COI: 1:CAS:528:DC%2BD3sXisV2msLs%3D, PID: 12676370
    • Menendez L, Lastra A, Fresno MF, Llames S, Meana A, Hidalgo A, Baamonde A (2003) Initial thermal heat hypoalgesia and delayed hyperalgesia in a murine model of bone cancer pain. Brain Res 969(1–2):102–109
    • (2003) Brain Res , vol.969 , Issue.1-2 , pp. 102-109
    • Menendez, L.1    Lastra, A.2    Fresno, M.F.3    Llames, S.4    Meana, A.5    Hidalgo, A.6    Baamonde, A.7
  • 26
    • 77952408526 scopus 로고    scopus 로고
    • Bilateral downregulation of Nav1.8 in dorsal root ganglia of rats with bone cancer pain induced by inoculation with Walker 256 breast tumor cells
    • Miao XR. Gao XF. Wu JX. Lu ZJ. Huang ZX. Li XQ. He C. Yu WF. 2010. Bilateral downregulation of Nav1.8 in dorsal root ganglia of rats with bone cancer pain induced by inoculation with Walker 256 breast tumor cells. BMC Cancer 10:216
    • (2010) BMC Cancer , vol.10 , pp. 216
  • 27
    • 0029113121 scopus 로고
    • Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2
    • COI: 1:CAS:528:DyaK2MXnvVKksLs%3D, PID: 7556175
    • Nystedt S, Emilsson K, Larsson AK, Strombeck B, Sundelin J (1995) Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2. Europ J Biochem 232(1):84–89
    • (1995) Europ J Biochem , vol.232 , Issue.1 , pp. 84-89
    • Nystedt, S.1    Emilsson, K.2    Larsson, A.K.3    Strombeck, B.4    Sundelin, J.5
  • 28
    • 0037223202 scopus 로고    scopus 로고
    • Contribution of injured and uninjured dorsal root ganglion neurons to pain behavior and the changes in gene expression following chronic constriction injury of the sciatic nerve in rats
    • COI: 1:CAS:528:DC%2BD38XpvVaitro%3D, PID: 12507701
    • Obata K, Yamanaka H, Fukuoka T, Yi D, Tokunaga A, Hashimoto N, Yoshikawa H, Noguchi K (2003) Contribution of injured and uninjured dorsal root ganglion neurons to pain behavior and the changes in gene expression following chronic constriction injury of the sciatic nerve in rats. Pain 101(1–2):65–77
    • (2003) Pain , vol.101 , Issue.1-2 , pp. 65-77
    • Obata, K.1    Yamanaka, H.2    Fukuoka, T.3    Yi, D.4    Tokunaga, A.5    Hashimoto, N.6    Yoshikawa, H.7    Noguchi, K.8
  • 29
    • 1642279517 scopus 로고    scopus 로고
    • Protease-activated receptors: contribution to physiology and disease
    • COI: 1:CAS:528:DC%2BD2cXjtlCktLY%3D, PID: 15044683
    • Ossovskaya VS, Bunnett NW (2004) Protease-activated receptors: contribution to physiology and disease. Physiol Rev 84(2):579–621
    • (2004) Physiol Rev , vol.84 , Issue.2 , pp. 579-621
    • Ossovskaya, V.S.1    Bunnett, N.W.2
  • 30
    • 84925468944 scopus 로고    scopus 로고
    • Combining the evidence from different drug trials
    • Q W. 2006. Combining the evidence from different drug trials. Edinburgh: University of Edinburgh
    • (2006) Edinburgh: University of Edinburgh
  • 31
    • 74049135647 scopus 로고    scopus 로고
    • Proteinase-activated receptor-4 (PAR4) activation leads to sensitization of rat joint primary afferents via a bradykinin B2 receptor-dependent mechanism
    • COI: 1:CAS:528:DC%2BC3cXislagtr8%3D, PID: 19889854
    • Russell FA, Veldhoen VE, Tchitchkan D, McDougall JJ (2010) Proteinase-activated receptor-4 (PAR4) activation leads to sensitization of rat joint primary afferents via a bradykinin B2 receptor-dependent mechanism. J Neurophysiol 103(1):155–163
    • (2010) J Neurophysiol , vol.103 , Issue.1 , pp. 155-163
    • Russell, F.A.1    Veldhoen, V.E.2    Tchitchkan, D.3    McDougall, J.J.4
  • 32
    • 78651482591 scopus 로고    scopus 로고
    • The pronociceptive effect of proteinase-activated receptor-4 stimulation in rat knee joints is dependent on mast cell activation
    • COI: 1:CAS:528:DC%2BC3MXmsVantQ%3D%3D, PID: 21238854
    • Russell FA, Zhan S, Dumas A, Lagarde S, Pouliot M, McDougall JJ (2011) The pronociceptive effect of proteinase-activated receptor-4 stimulation in rat knee joints is dependent on mast cell activation. Pain 152(2):354–360
    • (2011) Pain , vol.152 , Issue.2 , pp. 354-360
    • Russell, F.A.1    Zhan, S.2    Dumas, A.3    Lagarde, S.4    Pouliot, M.5    McDougall, J.J.6
  • 33
    • 0037900130 scopus 로고    scopus 로고
    • Mechanisms of protease-activated receptor-4 actions in cardiomyocytes role of src tyrosine kinase
    • COI: 1:CAS:528:DC%2BD3sXit1Kgurk%3D, PID: 12522105
    • Sabri A, Guo J, Elouardighi H, Darrow AL, Andrade-Gordon P, Steinberg SF (2003) Mechanisms of protease-activated receptor-4 actions in cardiomyocytes role of src tyrosine kinase. J Biol Chem 278(13):11714–11720
    • (2003) J Biol Chem , vol.278 , Issue.13 , pp. 11714-11720
    • Sabri, A.1    Guo, J.2    Elouardighi, H.3    Darrow, A.L.4    Andrade-Gordon, P.5    Steinberg, S.F.6
  • 36
    • 0036681940 scopus 로고    scopus 로고
    • Characterization of thrombin-induced leukocyte rolling and adherence: a potential proinflammatory role for proteinase-activated receptor-4
    • COI: 1:CAS:528:DC%2BD38XlslWht7w%3D, PID: 12133973
    • Vergnolle N, Derian CK, D’Andrea MR, Steinhoff M, Andrade-Gordon P (2002) Characterization of thrombin-induced leukocyte rolling and adherence: a potential proinflammatory role for proteinase-activated receptor-4. J Immunol 169(3):1467–1473
    • (2002) J Immunol , vol.169 , Issue.3 , pp. 1467-1473
    • Vergnolle, N.1    Derian, C.K.2    D’Andrea, M.R.3    Steinhoff, M.4    Andrade-Gordon, P.5
  • 37
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • COI: 1:CAS:528:DyaK3MXlsFehu7w%3D, PID: 1672265
    • Vu TK, Hung DT, Wheaton VI, Coughlin SR (1991) Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64(6):1057–1068
    • (1991) Cell , vol.64 , Issue.6 , pp. 1057-1068
    • Vu, T.K.1    Hung, D.T.2    Wheaton, V.I.3    Coughlin, S.R.4
  • 38
    • 84886642026 scopus 로고    scopus 로고
    • Protease-activated receptor 4 activation increases the expression of calcitonin gene-related peptide mRNA and protein in dorsal root ganglion neurons
    • COI: 1:CAS:528:DC%2BC3sXhsFOlsLbE, PID: 24105611
    • Wang Z, Chen D, Zhang Z, Zhang R, An S, Yu L (2013) Protease-activated receptor 4 activation increases the expression of calcitonin gene-related peptide mRNA and protein in dorsal root ganglion neurons. J Neurosci Res 91(12):1551–1562
    • (2013) J Neurosci Res , vol.91 , Issue.12 , pp. 1551-1562
    • Wang, Z.1    Chen, D.2    Zhang, Z.3    Zhang, R.4    An, S.5    Yu, L.6
  • 39
    • 17044393912 scopus 로고    scopus 로고
    • Expression of mRNA for four subtypes of the proteinase-activated receptor in rat dorsal root ganglia
    • COI: 1:CAS:528:DC%2BD2MXjtF2gs7k%3D, PID: 15829229
    • Zhu WJ, Yamanaka H, Obata K, Dai Y, Kobayashi K, Kozai T, Tokunaga A, Noguchi K (2005) Expression of mRNA for four subtypes of the proteinase-activated receptor in rat dorsal root ganglia. Brain Res 1041(2):205–211
    • (2005) Brain Res , vol.1041 , Issue.2 , pp. 205-211
    • Zhu, W.J.1    Yamanaka, H.2    Obata, K.3    Dai, Y.4    Kobayashi, K.5    Kozai, T.6    Tokunaga, A.7    Noguchi, K.8
  • 40
    • 0020525719 scopus 로고
    • Ethical guidelines for investigations of experimental pain in conscious animals
    • Zimmermann M (1983) Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16(2):109–110
    • (1983) Pain , vol.16 , Issue.2 , pp. 109-110
    • Zimmermann, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.