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Volumn 104, Issue 3, 2015, Pages 197-207

Pulmonary hypertension 2015: current definitions, terminology, and novel treatment options

Author keywords

Nice classification; Pulmonary arterial hypertension; Pulmonary hypertension; World symposium

Indexed keywords

AMBRISENTAN; BOSENTAN; ILOPROST; MACITENTAN; PROSTACYCLIN; RIOCIGUAT; SILDENAFIL; TADALAFIL; TREPROSTINIL; ANTIHYPERTENSIVE AGENT;

EID: 84925489360     PISSN: 18610684     EISSN: 18610692     Source Type: Journal    
DOI: 10.1007/s00392-014-0765-4     Document Type: Review
Times cited : (46)

References (59)
  • 1
    • 70049112901 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of pulmonary hypertension: the task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung transplantation (ISHLT)
    • PID: 19713419
    • Galiè N, Hoeper MM, Humbert M et al (2009) Guidelines for the diagnosis and treatment of pulmonary hypertension: the task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung transplantation (ISHLT). Eur Heart J 30:2493–2537
    • (2009) Eur Heart J , vol.30 , pp. 2493-2537
    • Galiè, N.1    Hoeper, M.M.2    Humbert, M.3
  • 2
    • 84890738424 scopus 로고    scopus 로고
    • Updated clinical classification of pulmonary hypertension
    • PID: 24355639
    • Simonneau G, Gatzoulis MA, Adatia I et al (2013) Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol 62(Suppl D):D34–D41
    • (2013) J Am Coll Cardiol , vol.62 , pp. 34-41
    • Simonneau, G.1    Gatzoulis, M.A.2    Adatia, I.3
  • 3
    • 67649579669 scopus 로고    scopus 로고
    • Updated clinical classification of pulmonary hypertension
    • PID: 19555858
    • Simonneau G, Robbins IM, Beghetti M et al (2009) Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol 54(Suppl S):S43–S54
    • (2009) J Am Coll Cardiol , vol.54 , pp. 43-54
    • Simonneau, G.1    Robbins, I.M.2    Beghetti, M.3
  • 4
    • 84890753066 scopus 로고    scopus 로고
    • Relevant issues in the pathology and pathobiology of pulmonary hypertension
    • PID: 24355640
    • Tuder RM, Archer SL, Dorfmüller P et al (2013) Relevant issues in the pathology and pathobiology of pulmonary hypertension. J Am Coll Cardiol 62(Suppl D):D4–D12
    • (2013) J Am Coll Cardiol , vol.62 , pp. 4-12
    • Tuder, R.M.1    Archer, S.L.2    Dorfmüller, P.3
  • 5
    • 84890687841 scopus 로고    scopus 로고
    • Genetics and genomics of pulmonary arterial hypertension
    • Soubrier F, Chung WK, Machado R et al (2013) Genetics and genomics of pulmonary arterial hypertension. J Am Coll Cardiol 63(Suppl D):D13–D21
    • (2013) J Am Coll Cardiol , vol.63 , pp. 13-21
    • Soubrier, F.1    Chung, W.K.2    Machado, R.3
  • 6
    • 84890722680 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension: epidemiology and registries
    • PID: 24355642
    • McGoon M, Benza RL, Escribano-Subias P et al (2013) Pulmonary arterial hypertension: epidemiology and registries. J Am Coll Cardiol 62(Suppl D):D51–D59
    • (2013) J Am Coll Cardiol , vol.62 , pp. 51-59
    • McGoon, M.1    Benza, R.L.2    Escribano-Subias, P.3
  • 7
    • 0023615359 scopus 로고
    • Primary pulmonary hypertension: a national prospective study
    • COI: 1:STN:280:DyaL2s3mvV2kug%3D%3D, PID: 3605900
    • Rich S, Dantzker DR, Ayres SM et al (1987) Primary pulmonary hypertension: a national prospective study. Ann Intern Med 107:216–223
    • (1987) Ann Intern Med , vol.107 , pp. 216-223
    • Rich, S.1    Dantzker, D.R.2    Ayres, S.M.3
  • 8
    • 0025837793 scopus 로고
    • Survival in patients with primary pulmonary hypertension
    • PID: 1863023
    • D’Alonzo GE, Barst RJ, Ayres SM et al (1991) Survival in patients with primary pulmonary hypertension. Ann Intern Med 115:343–349
    • (1991) Ann Intern Med , vol.115 , pp. 343-349
    • D’Alonzo, G.E.1    Barst, R.J.2    Ayres, S.M.3
  • 9
    • 77954758530 scopus 로고    scopus 로고
    • Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era
    • PID: 20585011
    • Humbert M, Sitbon O, Chaouat A et al (2010) Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era. Circulation 122:156–163
    • (2010) Circulation , vol.122 , pp. 156-163
    • Humbert, M.1    Sitbon, O.2    Chaouat, A.3
  • 10
    • 84885316129 scopus 로고    scopus 로고
    • Elderly patients diagnosed with idiopathic pulmonary arterial hypertension: results from the COMPERA registry
    • PID: 23164592
    • Hoeper MM, Huscher D, Ghofrani HA et al (2013) Elderly patients diagnosed with idiopathic pulmonary arterial hypertension: results from the COMPERA registry. Int J Cardiol 168:871–880
    • (2013) Int J Cardiol , vol.168 , pp. 871-880
    • Hoeper, M.M.1    Huscher, D.2    Ghofrani, H.A.3
  • 11
    • 84860142442 scopus 로고    scopus 로고
    • Current practice for determining pulmonary capillary wedge pressure predisposes to serious errors in the classification of patients with pulmonary hypertension
    • PID: 22520524
    • Ryan JJ, Rich JD, Thiruvoipati T et al (2012) Current practice for determining pulmonary capillary wedge pressure predisposes to serious errors in the classification of patients with pulmonary hypertension. Am Heart J 163:589–594
    • (2012) Am Heart J , vol.163 , pp. 589-594
    • Ryan, J.J.1    Rich, J.D.2    Thiruvoipati, T.3
  • 12
    • 84905660377 scopus 로고    scopus 로고
    • Reliance on end-expiratory wedge pressure leads to misclassification of pulmonary hypertension
    • (Epub ahead of print)
    • LeVarge BL, Pomerantsev E, Channick RN (2014) Reliance on end-expiratory wedge pressure leads to misclassification of pulmonary hypertension. Eur Respir J 43:425 (Epub ahead of print)
    • (2014) Eur Respir J , vol.43 , pp. 425
    • LeVarge, B.L.1    Pomerantsev, E.2    Channick, R.N.3
  • 13
    • 84890776626 scopus 로고    scopus 로고
    • Definition and diagnosis of pulmonary hypertension
    • PID: 24355641
    • Hoeper M, Bogaard HJ, Condliffe R et al (2013) Definition and diagnosis of pulmonary hypertension. J Am Coll Cardiol 62(Suppl D):D42–D50
    • (2013) J Am Coll Cardiol , vol.62 , pp. 42-50
    • Hoeper, M.1    Bogaard, H.J.2    Condliffe, R.3
  • 14
    • 83455162340 scopus 로고    scopus 로고
    • Rechtherzkatheter-Untersuchung bei pulmonaler Hypertonie
    • COI: 1:STN:280:DC%2BC38%2Fnt1aqsA%3D%3D, PID: 22160954
    • Rosenkranz S, Behr J, Ewert R, Ghofrani HA et al (2011) Rechtherzkatheter-Untersuchung bei pulmonaler Hypertonie. Dtsch Med Wochenschr 136:2601–2620
    • (2011) Dtsch Med Wochenschr , vol.136 , pp. 2601-2620
    • Rosenkranz, S.1    Behr, J.2    Ewert, R.3    Ghofrani, H.A.4
  • 15
    • 84890092196 scopus 로고    scopus 로고
    • Zero reference level for right heart catheterization
    • PID: 23794468
    • Kovacs G, Avian A, Olschewski A, Olschewski H (2013) Zero reference level for right heart catheterization. Eur Respir J 42:1586–1594
    • (2013) Eur Respir J , vol.42 , pp. 1586-1594
    • Kovacs, G.1    Avian, A.2    Olschewski, A.3    Olschewski, H.4
  • 16
    • 67649588196 scopus 로고    scopus 로고
    • Updated evidence-based treatment algorithm in pulmonary arterial hypertension
    • COI: 1:CAS:528:DC%2BC3cXkvVOksL4%3D, PID: 19555861
    • Barst RJ, Gibbs SR, Ghofrani HA et al (2009) Updated evidence-based treatment algorithm in pulmonary arterial hypertension. J Am Coll Cardiol 54(Suppl S):S78–S84
    • (2009) J Am Coll Cardiol , vol.54 , pp. 78-84
    • Barst, R.J.1    Gibbs, S.R.2    Ghofrani, H.A.3
  • 17
    • 84890574392 scopus 로고    scopus 로고
    • Updated treatment algorithm of pulmonary arterial hypertension
    • PID: 24355643
    • Galiè N, Corris PA, Frost A et al (2013) Updated treatment algorithm of pulmonary arterial hypertension. J Am Coll Cardiol 62(Suppl D):D60–D72
    • (2013) J Am Coll Cardiol , vol.62 , pp. 60-72
    • Galiè, N.1    Corris, P.A.2    Frost, A.3
  • 18
    • 84866307803 scopus 로고    scopus 로고
    • The discovery of N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N′-propyl-sulfamide (Macitentan), an orally active, potent dual endothelin receptor antagonist
    • COI: 1:CAS:528:DC%2BC38XhtFClurjP, PID: 22862294
    • Bolli MH, Boss C, Binkert C et al (2012) The discovery of N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N′-propyl-sulfamide (Macitentan), an orally active, potent dual endothelin receptor antagonist. J Med Chem 55:7849–7861
    • (2012) J Med Chem , vol.55 , pp. 7849-7861
    • Bolli, M.H.1    Boss, C.2    Binkert, C.3
  • 19
    • 84867562420 scopus 로고    scopus 로고
    • Slow receptor dissociation kinetics differentiate macitentan from other endothelin receptor antagonists in pulmonary arterial smooth muscle cells
    • COI: 1:CAS:528:DC%2BC38Xhs1Sitb%2FM, PID: 23077657
    • Gatfield J, Mueller Grandjean C, Sasse T, Clozel M, Nayler O (2012) Slow receptor dissociation kinetics differentiate macitentan from other endothelin receptor antagonists in pulmonary arterial smooth muscle cells. PLoS One 7:e47662
    • (2012) PLoS One , vol.7 , pp. 47662
    • Gatfield, J.1    Mueller Grandjean, C.2    Sasse, T.3    Clozel, M.4    Nayler, O.5
  • 20
    • 57349133022 scopus 로고    scopus 로고
    • Pharmacology of macitentan, an orally active tissue-targeting dual endothelin receptor antagonist
    • COI: 1:CAS:528:DC%2BD1cXhsVCjtLvO, PID: 18780830
    • Iglarz M, Binkert C, Morrison K et al (2008) Pharmacology of macitentan, an orally active tissue-targeting dual endothelin receptor antagonist. J Pharmacol Exp Ther 327:736–745
    • (2008) J Pharmacol Exp Ther , vol.327 , pp. 736-745
    • Iglarz, M.1    Binkert, C.2    Morrison, K.3
  • 21
    • 84883108940 scopus 로고    scopus 로고
    • Macitentan and morbidity and mortality in pulmonary arterial hypertension
    • COI: 1:CAS:528:DC%2BC3sXhtlyis7fP, PID: 23984728
    • Pulido T, Adzerikho I, Channick RN, For the SERAPHIN Investigators et al (2013) Macitentan and morbidity and mortality in pulmonary arterial hypertension. New Engl J Med 369:809–818
    • (2013) New Engl J Med , vol.369 , pp. 809-818
    • Pulido, T.1    Adzerikho, I.2    Channick, R.N.3    For the SERAPHIN Investigators4
  • 22
    • 33748312096 scopus 로고    scopus 로고
    • NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential
    • COI: 1:CAS:528:DC%2BD28XptVCltrw%3D, PID: 16955067
    • Evgenov OV, Pacher P, Schmidt PM et al (2006) NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential. Nat Rev Drug Discov 5:755–768
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 755-768
    • Evgenov, O.V.1    Pacher, P.2    Schmidt, P.M.3
  • 23
    • 77956664858 scopus 로고    scopus 로고
    • Riociguat for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension. A phase II study
    • COI: 1:STN:280:DC%2BC3cfntVelsA%3D%3D, PID: 20530034
    • Ghofrani HA, Hoeper M, Halank M et al (2010) Riociguat for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension. A phase II study. Eur Respir J 36:792–799
    • (2010) Eur Respir J , vol.36 , pp. 792-799
    • Ghofrani, H.A.1    Hoeper, M.2    Halank, M.3
  • 24
    • 84880721470 scopus 로고    scopus 로고
    • Riociguat for the treatment of pulmonary arterial hypertension
    • COI: 1:CAS:528:DC%2BC3sXhtF2nur7K, PID: 23883378
    • Ghofrani HA, Galiè N, Grimminger F, For the PATENT Investigators et al (2013) Riociguat for the treatment of pulmonary arterial hypertension. N Engl J Med 369:330–340
    • (2013) N Engl J Med , vol.369 , pp. 330-340
    • Ghofrani, H.A.1    Galiè, N.2    Grimminger, F.3    For the PATENT Investigators4
  • 25
    • 84880732460 scopus 로고    scopus 로고
    • Riociguat for the treatment of chronic thromboembolic pulmonary hypertension
    • COI: 1:CAS:528:DC%2BC3sXhtF2nur7J, PID: 23883377
    • Ghofrani HA, D`Armini AM, Grimminger F, For the CHEST Investigators et al (2013) Riociguat for the treatment of chronic thromboembolic pulmonary hypertension. N Engl J Med 369:319–329
    • (2013) N Engl J Med , vol.369 , pp. 319-329
    • Ghofrani, H.A.1    A.M.2    D3    Grimminger, F.5    For the CHEST Investigators6
  • 26
    • 84863528040 scopus 로고    scopus 로고
    • Selexipag, an oral, selective IP receptor agonist for the treatment of pulmonary arterial hypertension
    • COI: 1:CAS:528:DC%2BC38XhslSksLfM, PID: 22362844
    • Simonneau G, Lang I, Torbicki A, Hoeper MM, Delcrox M, Karlocai K, Galiè N (2012) Selexipag, an oral, selective IP receptor agonist for the treatment of pulmonary arterial hypertension. Eur Respir J 40:874–880
    • (2012) Eur Respir J , vol.40 , pp. 874-880
    • Simonneau, G.1    Lang, I.2    Torbicki, A.3    Hoeper, M.M.4    Delcrox, M.5    Karlocai, K.6    Galiè, N.7
  • 27
    • 84925495421 scopus 로고    scopus 로고
    • Actelion press release: selexipag meets primary endpoint in pivotal phase III GRIPHON outcome study in patients with pulmonary arterial hypertension () (Published June 16)
    • Actelion press release: selexipag meets primary endpoint in pivotal phase III GRIPHON outcome study in patients with pulmonary arterial hypertension (2014) (Published June 16)
    • (2014)
  • 29
    • 84874948946 scopus 로고    scopus 로고
    • Imatinib mesylate as add-on therapy for pulmonary arterial hypertension: results of the randomized IMPRES study
    • COI: 1:CAS:528:DC%2BC3sXjvFersbo%3D, PID: 23403476
    • Hoeper MM, Barst RJ, Bourge RC et al (2013) Imatinib mesylate as add-on therapy for pulmonary arterial hypertension: results of the randomized IMPRES study. Circulation 127:1128–1138
    • (2013) Circulation , vol.127 , pp. 1128-1138
    • Hoeper, M.M.1    Barst, R.J.2    Bourge, R.C.3
  • 30
    • 84925495420 scopus 로고    scopus 로고
    • GlaxoSmithKline/Gilead press release: first-line combination of ambrisentan and tadalafil reduces risk of clinical failure compared to monotherapy in pulmonary arterial hypertension outcomes study () (Published September 8)
    • GlaxoSmithKline/Gilead press release: first-line combination of ambrisentan and tadalafil reduces risk of clinical failure compared to monotherapy in pulmonary arterial hypertension outcomes study (2014) (Published September 8)
    • (2014)
  • 31
    • 85018146767 scopus 로고    scopus 로고
    • The AMBITION study: design and results
    • Galiè N, for the AMBITION Investigators (2014) The AMBITION study: design and results. Presented at ERS International Congress 2014 (abstract #2916)
    • (2014) Presented at ERS International Congress , pp. 2014
    • Galiè, N.1
  • 32
    • 84901855893 scopus 로고    scopus 로고
    • Upfront triple combination therapy in pulmonary arterial hypertension: a pilot study
    • PID: 24627535
    • Sitbon O, Jais X, Savale L et al (2014) Upfront triple combination therapy in pulmonary arterial hypertension: a pilot study. Eur Respir J 43:1691–1697
    • (2014) Eur Respir J , vol.43 , pp. 1691-1697
    • Sitbon, O.1    Jais, X.2    Savale, L.3
  • 33
    • 84891850978 scopus 로고    scopus 로고
    • Anticoagulation and survival in pulmonary arterial hypertension: results from the COMPERA registry
    • COI: 1:CAS:528:DC%2BC2cXktFCitA%3D%3D, PID: 24081973
    • Olsson KM, Delcroix M, Ghofrani HA et al (2014) Anticoagulation and survival in pulmonary arterial hypertension: results from the COMPERA registry. Circulation 129:57–65
    • (2014) Circulation , vol.129 , pp. 57-65
    • Olsson, K.M.1    Delcroix, M.2    Ghofrani, H.A.3
  • 34
    • 79960031695 scopus 로고    scopus 로고
    • Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: clinical prevalence, outcomes and mechanistic insights
    • COI: 1:CAS:528:DC%2BC3MXhtVajsrbI, PID: 21737024
    • Rhodes CJ, Howard LS, Busbridge M et al (2011) Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: clinical prevalence, outcomes and mechanistic insights. J Am Coll Cardiol 58:300–309
    • (2011) J Am Coll Cardiol , vol.58 , pp. 300-309
    • Rhodes, C.J.1    Howard, L.S.2    Busbridge, M.3
  • 35
    • 84892533041 scopus 로고    scopus 로고
    • Iron deficiency in systemic sclerosis patients with and without pulmonary hypertension
    • COI: 1:CAS:528:DC%2BC2cXhtVOht7Y%3D, PID: 24155365
    • Ruiter G, Lanser IJ, de Man FS et al (2014) Iron deficiency in systemic sclerosis patients with and without pulmonary hypertension. Rheumatology 53:285–292
    • (2014) Rheumatology , vol.53 , pp. 285-292
    • Ruiter, G.1    Lanser, I.J.2    de Man, F.S.3
  • 36
    • 84904268951 scopus 로고    scopus 로고
    • Ferric carboxymaltose improves exercise capacity and quality of life in patients with pulmonary arterial hypertension and iron deficiency: a pilot study
    • PID: 24880481, (Epub ahead of print)
    • Viethen T, Gerhardt F, Dumitrescu D, Knoop-Busch S, ten Freyhaus H, Rudolph TK, Baldus S, Rosenkranz S (2014) Ferric carboxymaltose improves exercise capacity and quality of life in patients with pulmonary arterial hypertension and iron deficiency: a pilot study. Int J Cardiol. doi:10.1016/j.ijcard.2014.04.233 (Epub ahead of print)
    • (2014) Int J Cardiol
    • Viethen, T.1    Gerhardt, F.2    Dumitrescu, D.3    Knoop-Busch, S.4    ten Freyhaus, H.5    Rudolph, T.K.6    Baldus, S.7    Rosenkranz, S.8
  • 37
    • 84855679210 scopus 로고    scopus 로고
    • Pulmonary pressures and death in heart failure
    • PID: 22240126
    • Bursi F, McNallan SM, Redfield MM et al (2012) Pulmonary pressures and death in heart failure. J Am Coll Cardiol 59:222–231
    • (2012) J Am Coll Cardiol , vol.59 , pp. 222-231
    • Bursi, F.1    McNallan, S.M.2    Redfield, M.M.3
  • 38
    • 62549141018 scopus 로고    scopus 로고
    • Pulmonary hypertension in heart failure with preserved ejection fraction: a community-based study
    • PID: 19324256
    • Lam CS, Roger VL, Rodeheffer RJ et al (2009) Pulmonary hypertension in heart failure with preserved ejection fraction: a community-based study. J Am Coll Cardiol 53:1119–1126
    • (2009) J Am Coll Cardiol , vol.53 , pp. 1119-1126
    • Lam, C.S.1    Roger, V.L.2    Rodeheffer, R.J.3
  • 39
    • 0035165175 scopus 로고    scopus 로고
    • Independent and additive prognostic value of right ventricular systolic function and pulmonary artery pressure in patients with chronic heart failure
    • COI: 1:STN:280:DC%2BD3M%2Fptlyrtw%3D%3D, PID: 11153735
    • Ghio S, Gavazzi A, Campana C et al (2001) Independent and additive prognostic value of right ventricular systolic function and pulmonary artery pressure in patients with chronic heart failure. J Am Coll Cardiol 37:183–188
    • (2001) J Am Coll Cardiol , vol.37 , pp. 183-188
    • Ghio, S.1    Gavazzi, A.2    Campana, C.3
  • 40
    • 84903772161 scopus 로고    scopus 로고
    • Borlaug BA: Right heart dysfunction in heart failure with preserved ejection fraction. Eur Heart J [Epub ahead of print]
    • Melenovsky V, Hwang SJ, Lin G, Redfield MM, Borlaug BA (2014) Right heart dysfunction in heart failure with preserved ejection fraction. Eur Heart J [Epub ahead of print]
    • (2014) Redfield MM
    • Melenovsky, V.1    Hwang, S.J.2    Lin, G.3
  • 41
    • 84881518465 scopus 로고    scopus 로고
    • Clinical features, hemodynamics, and outcomes of pulmonary hypertension due to chronic heart failure with reduced ejection fraction
    • PID: 24621932
    • Miller WL, Grill DE, Borlaug BA (2013) Clinical features, hemodynamics, and outcomes of pulmonary hypertension due to chronic heart failure with reduced ejection fraction. JACC Heart Fail 1:290–299
    • (2013) JACC Heart Fail , vol.1 , pp. 290-299
    • Miller, W.L.1    Grill, D.E.2    Borlaug, B.A.3
  • 42
    • 84904341524 scopus 로고    scopus 로고
    • Development of a risk score for outcome after transcatheter aortic valve implantation
    • PID: 24643728
    • Seiffert M, Sinning JM, Meyer A et al (2014) Development of a risk score for outcome after transcatheter aortic valve implantation. Clin Res Cardiol 103:631–640
    • (2014) Clin Res Cardiol , vol.103 , pp. 631-640
    • Seiffert, M.1    Sinning, J.M.2    Meyer, A.3
  • 43
    • 84858681268 scopus 로고    scopus 로고
    • Prognostic value of mild-to-moderate pulmonary hypertension in patients with severe aortic valve stenosis undergoing aortic valve replacement
    • PID: 21969256
    • Zuern CS, Eick C, Rizas K et al (2012) Prognostic value of mild-to-moderate pulmonary hypertension in patients with severe aortic valve stenosis undergoing aortic valve replacement. Clin Res Cardiol 101:81–88
    • (2012) Clin Res Cardiol , vol.101 , pp. 81-88
    • Zuern, C.S.1    Eick, C.2    Rizas, K.3
  • 44
    • 79951850287 scopus 로고    scopus 로고
    • Wireless pulmonary artery haemodynamic monitoring in chronic heart failure: a randomised controlled trial
    • PID: 21315441
    • Abraham WT, Adamson PB, Bourge RC et al (2011) Wireless pulmonary artery haemodynamic monitoring in chronic heart failure: a randomised controlled trial. Lancet 377:658–666
    • (2011) Lancet , vol.377 , pp. 658-666
    • Abraham, W.T.1    Adamson, P.B.2    Bourge, R.C.3
  • 45
    • 84872186964 scopus 로고    scopus 로고
    • The transpulmonary pressure gradient for the diagnoisis of pulmonary vascular disease
    • Naejie R, Vachiéry JL, Vanderpool R (2013) The transpulmonary pressure gradient for the diagnoisis of pulmonary vascular disease. Eur Respir J 41:217–223
    • (2013) Eur Respir J , vol.41 , pp. 217-223
    • Naejie, R.1    Vachiéry, J.L.2    Vanderpool, R.3
  • 46
    • 84874970007 scopus 로고    scopus 로고
    • Diastolic pulmonary vascular pressure gradient. A predictor of prognosis in out-of-proportion pulmonary hypertension
    • PID: 23580984
    • Gerges C, Gerges M, Lang MB et al (2013) Diastolic pulmonary vascular pressure gradient. A predictor of prognosis in out-of-proportion pulmonary hypertension. Chest 143:758–766
    • (2013) Chest , vol.143 , pp. 758-766
    • Gerges, C.1    Gerges, M.2    Lang, M.B.3
  • 47
    • 84855395428 scopus 로고    scopus 로고
    • Pulmonary hypertension due to left heart disease: updated recommendations of the Cologne Consensus Conference 2011
    • PID: 22221972
    • Rosenkranz S, Bondermann D, Buerke M et al (2011) Pulmonary hypertension due to left heart disease: updated recommendations of the Cologne Consensus Conference 2011. Int J Cardiol 154(Suppl):S34–S44
    • (2011) Int J Cardiol , vol.154 , pp. 34-44
    • Rosenkranz, S.1    Bondermann, D.2    Buerke, M.3
  • 48
    • 84890771619 scopus 로고    scopus 로고
    • Pulmonary hypertension due to left heart diseases
    • PID: 24355634
    • Vachiery JL, Adir Y, Barbera JA et al (2013) Pulmonary hypertension due to left heart diseases. J Am Coll Cardiol 62(Suppl D):D100–D108
    • (2013) J Am Coll Cardiol , vol.62 , pp. 100-108
    • Vachiery, J.L.1    Adir, Y.2    Barbera, J.A.3
  • 49
    • 79960396933 scopus 로고    scopus 로고
    • Pulmonary hypertension in heart failure with preserved ejection fraction: a target of phosphodiesterase-5 inhibition in a 1-year study
    • COI: 1:CAS:528:DC%2BC3MXoslOktrc%3D, PID: 21709061
    • Guazzi M, Vicenzi M, Arena R, Guazzi MD (2011) Pulmonary hypertension in heart failure with preserved ejection fraction: a target of phosphodiesterase-5 inhibition in a 1-year study. Circulation 124:164–174
    • (2011) Circulation , vol.124 , pp. 164-174
    • Guazzi, M.1    Vicenzi, M.2    Arena, R.3    Guazzi, M.D.4
  • 50
    • 84855822103 scopus 로고    scopus 로고
    • Therapeutic potential of sildenafil in patients with heart failure and reactive pulmonary hypertension—results of compassionate care treatment
    • PID: 22104986
    • Dumitrescu D, Seck C, Möhle L, Erdmann E, Rosenkranz S (2012) Therapeutic potential of sildenafil in patients with heart failure and reactive pulmonary hypertension—results of compassionate care treatment. Int J Cardiol 154:205–206
    • (2012) Int J Cardiol , vol.154 , pp. 205-206
    • Dumitrescu, D.1    Seck, C.2    Möhle, L.3    Erdmann, E.4    Rosenkranz, S.5
  • 51
    • 84875531214 scopus 로고    scopus 로고
    • Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: a randomized clinical trial
    • COI: 1:CAS:528:DC%2BC3sXlvFSgs7Y%3D, PID: 23478662
    • Redfield MM, Chen HH, Borlaug BA et al (2013) Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: a randomized clinical trial. JAMA 309:1268–1277
    • (2013) JAMA , vol.309 , pp. 1268-1277
    • Redfield, M.M.1    Chen, H.H.2    Borlaug, B.A.3
  • 52
    • 84881102246 scopus 로고    scopus 로고
    • Riociguat for patients with pulmonary hypertension caused by systolic left ventricular dysfunction: a phase IIb double-blind, randomized, placebo-controlled, dose-ranging hemodynamic study
    • COI: 1:CAS:528:DC%2BC3sXht1Slu7jL, PID: 23775260
    • Bonderman D, Ghio S, Felix SB, For the LEPHT Investigators et al (2013) Riociguat for patients with pulmonary hypertension caused by systolic left ventricular dysfunction: a phase IIb double-blind, randomized, placebo-controlled, dose-ranging hemodynamic study. Circulation 128:502–511
    • (2013) Circulation , vol.128 , pp. 502-511
    • Bonderman, D.1    Ghio, S.2    Felix, S.B.3    For the LEPHT Investigators4
  • 53
    • 84855381329 scopus 로고    scopus 로고
    • Pulmonary hypertension due to chronic lung disease. Updated recommendations of the cologne consensus conference 2011
    • PID: 22221973
    • Hoeper MM, Andreas S, Bastian A et al (2011) Pulmonary hypertension due to chronic lung disease. Updated recommendations of the cologne consensus conference 2011. Int J Cardiol 154(Suppl):S45–S53
    • (2011) Int J Cardiol , vol.154 , pp. 45-53
    • Hoeper, M.M.1    Andreas, S.2    Bastian, A.3
  • 54
    • 84865605188 scopus 로고    scopus 로고
    • Ventilatory and cardiocirculatory exercise profiles in COPD: the role of pulmonary hypertension
    • PID: 22556320
    • Boerrigter BG, Bogaard HJ, Trip P et al (2012) Ventilatory and cardiocirculatory exercise profiles in COPD: the role of pulmonary hypertension. Chest 142:1166–1174
    • (2012) Chest , vol.142 , pp. 1166-1174
    • Boerrigter, B.G.1    Bogaard, H.J.2    Trip, P.3
  • 55
    • 84890783241 scopus 로고    scopus 로고
    • Pulmonary hypertension in chronic lung diseases
    • PID: 24355635
    • Seeger W, Adir Y, Barbera JA et al (2013) Pulmonary hypertension in chronic lung diseases. J Am Coll Cardiol 62(Suppl D):D109–D116
    • (2013) J Am Coll Cardiol , vol.62 , pp. 109-116
    • Seeger, W.1    Adir, Y.2    Barbera, J.A.3
  • 56
    • 79951727777 scopus 로고    scopus 로고
    • Surgical management and outcome of patients with chronic thromboembolic pulmonary hypertension: results from an international prospective registry
    • PID: 21335128
    • Mayer E, Jenkins D, Lindner J et al (2011) Surgical management and outcome of patients with chronic thromboembolic pulmonary hypertension: results from an international prospective registry. J Thorac Cardiovasc Surg 141:702–710
    • (2011) J Thorac Cardiovasc Surg , vol.141 , pp. 702-710
    • Mayer, E.1    Jenkins, D.2    Lindner, J.3
  • 57
    • 84890688177 scopus 로고    scopus 로고
    • Chronic thromboembolic pulmonary hypertension
    • PID: 24355646
    • Kim NH, Delcroix M, Jenkins DP et al (2013) Chronic thromboembolic pulmonary hypertension. J Am Coll Cardiol 62(Suppl D):D92–D99
    • (2013) J Am Coll Cardiol , vol.62 , pp. 92-99
    • Kim, N.H.1    Delcroix, M.2    Jenkins, D.P.3
  • 58
    • 84862843592 scopus 로고    scopus 로고
    • Pulmonary endarterectomy: recent changes in a single institution´s experience of more than 2,700 patients
    • PID: 22626752
    • Madani MM, Auger WR, Pretorius V et al (2012) Pulmonary endarterectomy: recent changes in a single institution´s experience of more than 2,700 patients. Ann Thorac Surg 94:97–103
    • (2012) Ann Thorac Surg , vol.94 , pp. 97-103
    • Madani, M.M.1    Auger, W.R.2    Pretorius, V.3
  • 59
    • 84856239291 scopus 로고    scopus 로고
    • Percutaneous transluminal pulmonary angioplasty markedly improves pulmonary hemodynamics and long-term prognosis in patients with chronic thromboembolic pulmonary hypertension
    • PID: 22185711
    • Sugimura K, Fukumoto Y, Satoh K et al (2012) Percutaneous transluminal pulmonary angioplasty markedly improves pulmonary hemodynamics and long-term prognosis in patients with chronic thromboembolic pulmonary hypertension. Circ J 76:485–488
    • (2012) Circ J , vol.76 , pp. 485-488
    • Sugimura, K.1    Fukumoto, Y.2    Satoh, K.3


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