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Volumn 125, Issue 12, 2015, Pages 1922-1931

DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features

(26)  Arribas, Alberto J a   Rinaldi, Andrea a   Mensah, Afua A a   Kwee, Ivo a,b   Cascione, Luciano a,c   Robles, Eloy F d   Martinez Climent, Jose A d   Oscier, David e   Arcaini, Luca f   Baldini, Luca g   Marasca, Roberto h   Thieblemont, Catherine i   Briere, Josette i   Forconi, Francesco j,k   Zamò, Alberto l   Bonifacio, Massimiliano l   Mollejo, Manuela m   Facchetti, Fabio n   Dirnhofer, Stephan o   Ponzoni, Maurilio p   more..


Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; POLYCOMB REPRESSIVE COMPLEX 2;

EID: 84925357071     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-08-596247     Document Type: Article
Times cited : (50)

References (51)
  • 2
    • 79551650559 scopus 로고    scopus 로고
    • Genomewide DNA profiling of marginal zone lymphomas identifies subtype-specific lesions with an impact on the clinical outcome
    • Rinaldi A, Mian M, Chigrinova E, et al. Genomewide DNA profiling of marginal zone lymphomas identifies subtype-specific lesions with an impact on the clinical outcome. Blood. 2011;117(5):1595-1604.
    • (2011) Blood , vol.117 , Issue.5 , pp. 1595-1604
    • Rinaldi, A.1    Mian, M.2    Chigrinova, E.3
  • 3
    • 77956592193 scopus 로고    scopus 로고
    • Cytogenetic aberrations and their prognostic value in a series of 330 splenic marginal zone B-cell lymphomas: A multicenter study of the Splenic B-Cell Lymphoma Group
    • Salido M, Baró C, Oscier D, et al. Cytogenetic aberrations and their prognostic value in a series of 330 splenic marginal zone B-cell lymphomas: a multicenter study of the Splenic B-Cell Lymphoma Group. Blood. 2010;116(9):1479-1488.
    • (2010) Blood , vol.116 , Issue.9 , pp. 1479-1488
    • Salido, M.1    Baró, C.2    Oscier, D.3
  • 4
    • 84866429139 scopus 로고    scopus 로고
    • The coding genome of splenic marginal zone lymphoma: Activation of NOTCH2 and other pathways regulating marginal zone development
    • Rossi D, Trifonov V, Fangazio M, et al. The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development. J Exp Med. 2012;209(9):1537-1551.
    • (2012) J Exp Med , vol.209 , Issue.9 , pp. 1537-1551
    • Rossi, D.1    Trifonov, V.2    Fangazio, M.3
  • 5
    • 84866392764 scopus 로고    scopus 로고
    • Whole-genome sequencing identifies recurrent somatic NOTCH2 mutations in splenic marginal zone lymphoma
    • Kiel MJ, Velusamy T, Betz BL, et al. Whole-genome sequencing identifies recurrent somatic NOTCH2 mutations in splenic marginal zone lymphoma. J Exp Med. 2012;209(9):1553-1565.
    • (2012) J Exp Med , vol.209 , Issue.9 , pp. 1553-1565
    • Kiel, M.J.1    Velusamy, T.2    Betz, B.L.3
  • 6
    • 84892529734 scopus 로고    scopus 로고
    • Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma
    • Parry M, Rose-Zerilli MJ, Gibson J, et al. Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma. PLoS ONE. 2013;8(12):e83244.
    • (2013) PLoS ONE , vol.8 , Issue.12 , pp. e83244
    • Parry, M.1    Rose-Zerilli, M.J.2    Gibson, J.3
  • 7
    • 84902121064 scopus 로고    scopus 로고
    • Whole-exome sequencing in splenic marginal zone lymphoma reveals mutations in genes involved in marginal zone differentiation
    • Martínez N, Almaraz C, Vaqué JP, et al. Whole-exome sequencing in splenic marginal zone lymphoma reveals mutations in genes involved in marginal zone differentiation. Leukemia. 2014;28(6):1334-1340.
    • (2014) Leukemia , vol.28 , Issue.6 , pp. 1334-1340
    • Martínez, N.1    Almaraz, C.2    Vaqué, J.P.3
  • 8
    • 84897498688 scopus 로고    scopus 로고
    • Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes
    • Chambwe N, Kormaksson M, Geng H, et al. Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes. Blood. 2014;123(11):1699-1708.
    • (2014) Blood , vol.123 , Issue.11 , pp. 1699-1708
    • Chambwe, N.1    Kormaksson, M.2    Geng, H.3
  • 9
    • 84911367433 scopus 로고    scopus 로고
    • Hypermethylation of p15 gene in diffuse - large B-cell lymphoma: Association with less aggressiveness of the disease
    • Krajnović M, Jovanović MP, Mihaljević B, et al. Hypermethylation of p15 gene in diffuse - large B-cell lymphoma: association with less aggressiveness of the disease. Clin Transl Sci. 2014;7(5):384-390.
    • (2014) Clin Transl Sci , vol.7 , Issue.5 , pp. 384-390
    • Krajnović, M.1    Jovanović, M.P.2    Mihaljević, B.3
  • 10
    • 84902952782 scopus 로고    scopus 로고
    • Quantification of DAPK1 promoter methylation in bone marrow and peripheral blood as a follicular lymphoma biomarker
    • Giachelia M, Bozzoli V, D'Alò F, et al. Quantification of DAPK1 promoter methylation in bone marrow and peripheral blood as a follicular lymphoma biomarker. J Mol Diagn. 2014;16(4):467-476.
    • (2014) J Mol Diagn , vol.16 , Issue.4 , pp. 467-476
    • Giachelia, M.1    Bozzoli, V.2    D'Alò, F.3
  • 11
    • 84880425891 scopus 로고    scopus 로고
    • Mechanisms of epigenetic deregulation in lymphoid neoplasms
    • Jiang Y, Hatzi K, Shaknovich R. Mechanisms of epigenetic deregulation in lymphoid neoplasms. Blood. 2013;121(21):4271-4279.
    • (2013) Blood , vol.121 , Issue.21 , pp. 4271-4279
    • Jiang, Y.1    Hatzi, K.2    Shaknovich, R.3
  • 12
    • 84874116695 scopus 로고    scopus 로고
    • Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain
    • James LI, Barsyte-Lovejoy D, Zhong N, et al. Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain. Nat Chem Biol. 2013;9(3):184-191.
    • (2013) Nat Chem Biol , vol.9 , Issue.3 , pp. 184-191
    • James, L.I.1    Barsyte-Lovejoy, D.2    Zhong, N.3
  • 13
    • 84884532954 scopus 로고    scopus 로고
    • Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer
    • Kim W, Bird GH, Neff T, et al. Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer. Nat Chem Biol. 2013;9(10):643-650.
    • (2013) Nat Chem Biol , vol.9 , Issue.10 , pp. 643-650
    • Kim, W.1    Bird, G.H.2    Neff, T.3
  • 14
    • 84903182870 scopus 로고    scopus 로고
    • The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells
    • Zhang J, Jima D, Moffitt AB, et al. The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells. Blood. 2014;123(19):2988-2996.
    • (2014) Blood , vol.123 , Issue.19 , pp. 2988-2996
    • Zhang, J.1    Jima, D.2    Moffitt, A.B.3
  • 15
    • 40749143143 scopus 로고    scopus 로고
    • Splenic marginal zone lymphoma proposals for a revision of diagnostic, staging and therapeutic criteria
    • Matutes E, Oscier D, Montalban C, et al. Splenic marginal zone lymphoma proposals for a revision of diagnostic, staging and therapeutic criteria. Leukemia. 2008;22(3):487-495.
    • (2008) Leukemia , vol.22 , Issue.3 , pp. 487-495
    • Matutes, E.1    Oscier, D.2    Montalban, C.3
  • 16
    • 84884988160 scopus 로고    scopus 로고
    • Promoter methylation patterns in Richter syndrome affect stem-cell maintenance and cell cycle regulation and differ from de novo diffuse large B-cell lymphoma
    • Rinaldi A, Mensah AA, Kwee I, et al. Promoter methylation patterns in Richter syndrome affect stem-cell maintenance and cell cycle regulation and differ from de novo diffuse large B-cell lymphoma. Br J Haematol. 2013;163(2):194-204.
    • (2013) Br J Haematol , vol.163 , Issue.2 , pp. 194-204
    • Rinaldi, A.1    Mensah, A.A.2    Kwee, I.3
  • 17
    • 84865572178 scopus 로고    scopus 로고
    • High-throughput sequencing analysis of the chromosome 7q32 deletion reveals IRF5 as a potential tumour suppressor in splenic marginalzone lymphoma
    • Fresquet V, Robles EF, Parker A, et al. High-throughput sequencing analysis of the chromosome 7q32 deletion reveals IRF5 as a potential tumour suppressor in splenic marginalzone lymphoma. Br J Haematol. 2012;158(6):712-726.
    • (2012) Br J Haematol , vol.158 , Issue.6 , pp. 712-726
    • Fresquet, V.1    Robles, E.F.2    Parker, A.3
  • 18
    • 78349301947 scopus 로고    scopus 로고
    • Immunogenetics features and genomic lesions in splenic marginal zone lymphoma
    • Rinaldi A, Forconi F, Arcaini L, et al. Immunogenetics features and genomic lesions in splenic marginal zone lymphoma. Br J Haematol. 2010;151(5):435-439.
    • (2010) Br J Haematol , vol.151 , Issue.5 , pp. 435-439
    • Rinaldi, A.1    Forconi, F.2    Arcaini, L.3
  • 19
    • 25444502962 scopus 로고    scopus 로고
    • In vitro activity of cyclin-dependent kinase inhibitor CYC202 (Seliciclib, R-roscovitine) in mantle cell lymphomas
    • Lacrima K, Valentini A, Lambertini C, et al. In vitro activity of cyclin-dependent kinase inhibitor CYC202 (Seliciclib, R-roscovitine) in mantle cell lymphomas. Ann Oncol. 2005;16(7):1169-1176.
    • (2005) Ann Oncol , vol.16 , Issue.7 , pp. 1169-1176
    • Lacrima, K.1    Valentini, A.2    Lambertini, C.3
  • 20
    • 81555196342 scopus 로고    scopus 로고
    • HDAC inhibitors and decitabine are highly synergistic and associated with unique gene-expression and epigenetic profiles in models of DLBCL
    • Kalac M, Scotto L, Marchi E, et al. HDAC inhibitors and decitabine are highly synergistic and associated with unique gene-expression and epigenetic profiles in models of DLBCL. Blood. 2011;118(20):5506-5516.
    • (2011) Blood , vol.118 , Issue.20 , pp. 5506-5516
    • Kalac, M.1    Scotto, L.2    Marchi, E.3
  • 21
    • 84856306090 scopus 로고    scopus 로고
    • Genome-wide DNA methylation profiling using Infinium® assay
    • Bibikova M, Le J, Barnes B, et al. Genome-wide DNA methylation profiling using Infinium® assay. Epigenomics. 2009;1(1):177-200.
    • (2009) Epigenomics , vol.1 , Issue.1 , pp. 177-200
    • Bibikova, M.1    Le, J.2    Barnes, B.3
  • 22
    • 27644464861 scopus 로고    scopus 로고
    • EXPANDER - an integrative program suite for microarray data analysis
    • Shamir R, Maron-Katz A, Tanay A, et al. EXPANDER - an integrative program suite for microarray data analysis. BMC Bioinformatics. 2005;6:232.
    • (2005) BMC Bioinformatics , vol.6 , pp. 232
    • Shamir, R.1    Maron-Katz, A.2    Tanay, A.3
  • 23
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc. 2009;4(1):44-57.
    • (2009) Nat Protoc , vol.4 , Issue.1 , pp. 44-57
    • Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 24
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA. 2005;102(43):15545-15550.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.43 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3
  • 26
    • 0242490780 scopus 로고    scopus 로고
    • Cytoscape: A software environment for integrated models of biomolecular interaction networks
    • Shannon P, Markiel A, Ozier O, et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res. 2003;13(11):2498-2504.
    • (2003) Genome Res , vol.13 , Issue.11 , pp. 2498-2504
    • Shannon, P.1    Markiel, A.2    Ozier, O.3
  • 27
    • 84886737842 scopus 로고    scopus 로고
    • Transcriptional landscapes of emerging autoimmunity: Transient aberrations in the targeted tissue's extracellular milieu precede immune responses in Sjögren's syndrome
    • Delaleu N, Nguyen CQ, Tekle KM, Jonsson R, Peck AB. Transcriptional landscapes of emerging autoimmunity: transient aberrations in the targeted tissue's extracellular milieu precede immune responses in Sjögren's syndrome. Arthritis Res Ther. 2013;15(5):R174.
    • (2013) Arthritis Res Ther , vol.15 , Issue.5 , pp. R174
    • Delaleu, N.1    Nguyen, C.Q.2    Tekle, K.M.3    Jonsson, R.4    Peck, A.B.5
  • 28
    • 36448962694 scopus 로고    scopus 로고
    • MethylScreen: DNA methylation density monitoring using quantitative PCR
    • Holemon H, Korshunova Y, Ordway JM, et al. MethylScreen: DNA methylation density monitoring using quantitative PCR. Biotechniques. 2007;43(5):683-693.
    • (2007) Biotechniques , vol.43 , Issue.5 , pp. 683-693
    • Holemon, H.1    Korshunova, Y.2    Ordway, J.M.3
  • 29
    • 33745066935 scopus 로고    scopus 로고
    • Integruppo Italiano Linfomi. Splenic marginal zone lymphoma: A prognostic model for clinical use
    • Arcaini L, Lazzarino M, Colombo N, et al Integruppo Italiano Linfomi. Splenic marginal zone lymphoma: a prognostic model for clinical use. Blood. 2006;107(12):4643-4649.
    • (2006) Blood , vol.107 , Issue.12 , pp. 4643-4649
    • Arcaini, L.1    Lazzarino, M.2    Colombo, N.3
  • 30
    • 84879994377 scopus 로고    scopus 로고
    • Splenic marginal zone lymphoma: Comprehensive analysis of gene expression and miRNA profiling
    • Arribas AJ, Gómez-Abad C, Sánchez-Beato M, et al. Splenic marginal zone lymphoma: comprehensive analysis of gene expression and miRNA profiling. Mod Pathol. 2013;26(7):889-901.
    • (2013) Mod Pathol , vol.26 , Issue.7 , pp. 889-901
    • Arribas, A.J.1    Gómez-Abad, C.2    Sánchez-Beato, M.3
  • 31
    • 80855133512 scopus 로고    scopus 로고
    • Alteration of BIRC3 and multiple other NF-κB pathway genes in splenic marginal zone lymphoma
    • Rossi D, Deaglio S, Dominguez-Sola D, et al. Alteration of BIRC3 and multiple other NF-κB pathway genes in splenic marginal zone lymphoma. Blood. 2011;118(18):4930-4934.
    • (2011) Blood , vol.118 , Issue.18 , pp. 4930-4934
    • Rossi, D.1    Deaglio, S.2    Dominguez-Sola, D.3
  • 32
    • 66549086135 scopus 로고    scopus 로고
    • The NF-KB negative regulator TNFAIP3 (A20) is commonly inactivated by somatic mutations and genomic deletions in marginal zone B-cell lymphomas
    • Novak U, Rinaldi A, Kwee I, et al. The NF-KB negative regulator TNFAIP3 (A20) is commonly inactivated by somatic mutations and genomic deletions in marginal zone B-cell lymphomas. Blood. 2009;113(20):4918-4921.
    • (2009) Blood , vol.113 , Issue.20 , pp. 4918-4921
    • Novak, U.1    Rinaldi, A.2    Kwee, I.3
  • 33
    • 8744307100 scopus 로고    scopus 로고
    • Constitutive expression of the AP-1 transcription factors c-jun, junD, junB, and c-fos and the marginal zone B-cell transcription factor Notch2 in splenic marginal zone lymphoma
    • Trøen G, Nygaard V, Jenssen TK, et al. Constitutive expression of the AP-1 transcription factors c-jun, junD, junB, and c-fos and the marginal zone B-cell transcription factor Notch2 in splenic marginal zone lymphoma. J Mol Diagn. 2004;6(4):297-307.
    • (2004) J Mol Diagn , vol.6 , Issue.4 , pp. 297-307
    • Trøen, G.1    Nygaard, V.2    Jenssen, T.K.3
  • 34
    • 75749124332 scopus 로고    scopus 로고
    • Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
    • Morin RD, Johnson NA, Severson TM, et al. Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nat Genet. 2010;42(2):181-185.
    • (2010) Nat Genet , vol.42 , Issue.2 , pp. 181-185
    • Morin, R.D.1    Johnson, N.A.2    Severson, T.M.3
  • 35
    • 57649124289 scopus 로고    scopus 로고
    • Repression of E-cadherin by the polycomb group protein EZH2 in cancer
    • Cao Q, Yu J, Dhanasekaran SM, et al. Repression of E-cadherin by the polycomb group protein EZH2 in cancer. Oncogene. 2008;27(58):7274-7284.
    • (2008) Oncogene , vol.27 , Issue.58 , pp. 7274-7284
    • Cao, Q.1    Yu, J.2    Dhanasekaran, S.M.3
  • 36
    • 0142105414 scopus 로고    scopus 로고
    • EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
    • Bracken AP, Pasini D, Capra M, Prosperini E, Colli E, Helin K. EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer. EMBO J. 2003;22(20):5323-5335.
    • (2003) EMBO J , vol.22 , Issue.20 , pp. 5323-5335
    • Bracken, A.P.1    Pasini, D.2    Capra, M.3    Prosperini, E.4    Colli, E.5    Helin, K.6
  • 37
    • 84888803072 scopus 로고    scopus 로고
    • A key role for EZH2 in epigenetic silencing of HOX genes in mantle cell lymphoma
    • Kanduri M, Sander B, Ntoufa S, et al. A key role for EZH2 in epigenetic silencing of HOX genes in mantle cell lymphoma. Epigenetics. 2013;8(12):1280-1288.
    • (2013) Epigenetics , vol.8 , Issue.12 , pp. 1280-1288
    • Kanduri, M.1    Sander, B.2    Ntoufa, S.3
  • 38
    • 77956579875 scopus 로고    scopus 로고
    • KLF4 is a tumor suppressor in B-cell non-Hodgkin lymphoma and in classic Hodgkin lymphoma
    • Guan H, Xie L, Leithäuser F, et al. KLF4 is a tumor suppressor in B-cell non-Hodgkin lymphoma and in classic Hodgkin lymphoma. Blood. 2010;116(9):1469-1478.
    • (2010) Blood , vol.116 , Issue.9 , pp. 1469-1478
    • Guan, H.1    Xie, L.2    Leithäuser, F.3
  • 39
    • 84904886249 scopus 로고    scopus 로고
    • Expression of KLF4 is a predictive marker for survival in pediatric Burkitt lymphoma
    • Valencia-Hipólito A, Hernandez-Atenógenes M, Vega GG, et al. Expression of KLF4 is a predictive marker for survival in pediatric Burkitt lymphoma. Leuk Lymphoma. 2014;55(8):1806-1814.
    • (2014) Leuk Lymphoma , vol.55 , Issue.8 , pp. 1806-1814
    • Valencia-Hipólito, A.1    Hernandez-Atenógenes, M.2    Vega, G.G.3
  • 40
    • 78149470355 scopus 로고    scopus 로고
    • KLF4 promotes hydrogenperoxide-induced apoptosis of chronic myeloid leukemia cells involving the bcl-2/bax pathway
    • Li Z, Zhao J, Li Q, et al. KLF4 promotes hydrogenperoxide-induced apoptosis of chronic myeloid leukemia cells involving the bcl-2/bax pathway. Cell Stress Chaperones. 2010;15(6):905-912.
    • (2010) Cell Stress Chaperones , vol.15 , Issue.6 , pp. 905-912
    • Li, Z.1    Zhao, J.2    Li, Q.3
  • 41
    • 20144385625 scopus 로고    scopus 로고
    • Differential gene expression in anaplastic lymphoma kinase-positive and anaplastic lymphoma kinase-negative anaplastic large cell lymphomas
    • Thompson MA, Stumph J, Henrickson SE, et al. Differential gene expression in anaplastic lymphoma kinase-positive and anaplastic lymphoma kinase-negative anaplastic large cell lymphomas. Hum Pathol. 2005;36(5):494-504.
    • (2005) Hum Pathol , vol.36 , Issue.5 , pp. 494-504
    • Thompson, M.A.1    Stumph, J.2    Henrickson, S.E.3
  • 42
    • 0028918388 scopus 로고
    • Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6
    • Hirai H, Roussel MF, Kato JY, Ashmun RA, Sherr CJ. Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6. Mol Cell Biol. 1995;15(5):2672-2681.
    • (1995) Mol Cell Biol , vol.15 , Issue.5 , pp. 2672-2681
    • Hirai, H.1    Roussel, M.F.2    Kato, J.Y.3    Ashmun, R.A.4    Sherr, C.J.5
  • 43
    • 84885360790 scopus 로고    scopus 로고
    • RUNX family participates in the regulation of p53-dependent DNA damage response
    • Ozaki T, Nakagawara A, Nagase H. RUNX family participates in the regulation of p53-dependent DNA damage response. Int J Genomics. 2013;2013:271347.
    • (2013) Int J Genomics , vol.2013 , pp. 271347
    • Ozaki, T.1    Nakagawara, A.2    Nagase, H.3
  • 44
    • 0028569767 scopus 로고
    • Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen
    • Smith ML, Chen IT, Zhan Q, et al. Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen. Science. 1994;266(5189):1376-1380.
    • (1994) Science , vol.266 , Issue.5189 , pp. 1376-1380
    • Smith, M.L.1    Chen, I.T.2    Zhan, Q.3
  • 45
    • 84878186386 scopus 로고    scopus 로고
    • Concise drug review: Azacitidine and decitabine
    • Derissen EJ, Beijnen JH, Schellens JH. Concise drug review: azacitidine and decitabine. Oncologist. 2013;18(5):619-624.
    • (2013) Oncologist , vol.18 , Issue.5 , pp. 619-624
    • Derissen, E.J.1    Beijnen, J.H.2    Schellens, J.H.3
  • 46
    • 84925375324 scopus 로고    scopus 로고
    • The BET Bromodomain inhibitor OTX015 affects pathogenetic pathways in pre-clinical B-cell tumor models and synergizes with targeted drugs
    • Boi M, Gaudio E, Bonetti P, et al. The BET Bromodomain inhibitor OTX015 affects pathogenetic pathways in pre-clinical B-cell tumor models and synergizes with targeted drugs. Clin Cancer Res. 2015.
    • (2015) Clin Cancer Res
    • Boi, M.1    Gaudio, E.2    Bonetti, P.3
  • 47
    • 84925375323 scopus 로고    scopus 로고
    • Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response
    • Mensah AA, Kwee I, Gaudio E, et al. Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response. Oncotarget. 2014.
    • (2014) Oncotarget
    • Mensah, A.A.1    Kwee, I.2    Gaudio, E.3
  • 48
    • 84924983348 scopus 로고    scopus 로고
    • Preclinical antitumor activity of ST7612AA1: A novel second generation oral histone deacetylase (HDAC) inhibitor
    • Vesci L, Bernasconi E, Milazzo FM, et al. Preclinical antitumor activity of ST7612AA1: a novel second generation oral histone deacetylase (HDAC) inhibitor. Oncotarget. 2014.
    • (2014) Oncotarget
    • Vesci, L.1    Bernasconi, E.2    Milazzo, F.M.3
  • 49
    • 84871806385 scopus 로고    scopus 로고
    • Bruton tyrosine kinase inhibitor ibrutinib (PCI-32765) has significant activity in patients with relapsed/refractory B-cell malignancies
    • Advani RH, Buggy JJ, Sharman JP, et al. Bruton tyrosine kinase inhibitor ibrutinib (PCI-32765) has significant activity in patients with relapsed/refractory B-cell malignancies. J Clin Oncol. 2013;31(1):88-94.
    • (2013) J Clin Oncol , vol.31 , Issue.1 , pp. 88-94
    • Advani, R.H.1    Buggy, J.J.2    Sharman, J.P.3
  • 50
    • 84901703641 scopus 로고    scopus 로고
    • Idelalisib, a selective inhibitor of phosphatidylinositol 3-kinase-δ, as therapy for previously treated indolent non-Hodgkin lymphoma
    • Flinn IW, Kahl BS, Leonard JP, et al. Idelalisib, a selective inhibitor of phosphatidylinositol 3-kinase-δ, as therapy for previously treated indolent non-Hodgkin lymphoma. Blood. 2014;123(22):3406-3413.
    • (2014) Blood , vol.123 , Issue.22 , pp. 3406-3413
    • Flinn, I.W.1    Kahl, B.S.2    Leonard, J.P.3
  • 51
    • 77449160650 scopus 로고    scopus 로고
    • Results of a phase 2 study of bortezomib in patients with relapsed or refractory indolent lymphoma
    • Di Bella N, Taetle R, Kolibaba K, et al. Results of a phase 2 study of bortezomib in patients with relapsed or refractory indolent lymphoma. Blood. 2010;115(3):475-480.
    • (2010) Blood , vol.115 , Issue.3 , pp. 475-480
    • Di Bella, N.1    Taetle, R.2    Kolibaba, K.3


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