Temozolomide in low-grade gliomas: Living longer and better

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 86, Issue 4, 2015, Pages 359-360

  Rees, Jeremy ^a  

^a NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

TEMOZOLOMIDE; ALKYLATING AGENT; DACARBAZINE;

BRAIN SURGERY; CANCER CHEMOTHERAPY; CANCER GRADING; CANCER PROGNOSIS; CANCER RADIOTHERAPY; CANCER SURVIVAL; CHROMOSOME 1P; CHROMOSOME DELETION; CLINICAL FEATURE; DISEASE CONTROL; EPILEPSY; FOCAL EPILEPSY; GLIOMA; HISTOPATHOLOGY; HUMAN; LONG TERM SURVIVAL; NOTE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; QUALITY OF LIFE; SURVIVAL TIME; TREATMENT OUTCOME; TUMOR MICROENVIRONMENT; ANALOGS AND DERIVATIVES; BRAIN NEOPLASMS; COMPLICATION; FEMALE; MALE; SEIZURES;

ANTINEOPLASTIC AGENTS, ALKYLATING; BRAIN NEOPLASMS; DACARBAZINE; FEMALE; GLIOMA; HUMANS; MALE; SEIZURES;

EID: 84925345366     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp-2014-308880     Document Type: Note

References (9)

1. Pallud J, Audureau E, Blonski M, et al. Epileptic seizures in diffuse low-grade gliomas in adults. Brain 2014;137:449-62.
2. Van Breemen MSM, Rijsman RM, Taphoorn MJB, et al. Efficacy of anti-epileptic drugs in patients with gliomas and seizures. J Neurology 2009;256:1519-26.
3. Koekkoek JA, Dirven L, Heimans JJ, et al. Seizure reduction in a low-grade glioma: more than a beneficial side effect of temozolomide. J Neurol Neurosurg Psychiatry 2015;86:366-73.
4. Van den Bent MJ, Afra D, de Witte O, et al. Long-term ef ficacy of early versus delayed radiotherapy for low-grade astrocytoma and oligodendroglioma in adults: the EORTC 22845 randomised trial. Lancet 2005;366:985-90.
5. Baumert BG, Mason WP, Ryan G, et al. Temozolomide chemotherapy versus radiotherapy in molecularly characterized (1p loss) low-grade glioma: a randomized phase III intergroup study by the EORTC/NCIC-CTG/TROG/MRC-CTU (EORTC 22033-26033). J Clin Oncol 2013. (suppl; abstr 2007).
6. Chang EF, Potts MB, Keles GE, et al. Seizure characteristics and control following resection in 332 patients with low-grade gliomas. J Neurosurg 2008;108:227-35.
7. Rudà R, Magliola U, Bertero L, et al. Seizure control following radiotherapy in patients with diffuse gliomas: a retrospective study. Neuro Oncol 2013;15:1739-49.
8. Pace A, Vidiri A, Galie E, et al. Temozolomide chemotherapy for progressive low-grade glioma: clinical benefits and radiological response. Ann Oncol 2003;14:1722-6.
9. Liubinas SV, D'Abaco GM, Moffat BM, et al. IDH1 mutation is associated with seizures and protoplasmic subtype in patients with low-grade gliomas. Epilepsia 2014. Published online first. doi:10.1111/epi.12662.