Novel vaccination approach for dengue infection based on recombinant immune complex universal platform

Vaccine

Volumn 33, Issue 15, 2015, Pages 1830-1838

  Kim, Mi Young ^a,c   Reljic, Rajko ^c   Kilbourne, Jacquelyn ^a   Ceballos Olvera, Ivonne ^b   Yang, Moon Sik ^d   Reyes del Valle, Jorge ^b   Mason, Hugh S ^a,b  

^a ARIZONA STATE UNIVERSITY   (United States)

^b ARIZONA STATE UNIVERSITY   (United States)

^c ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^d Chonbuk National University   (South Korea)

Author keywords

Dengue; Ebola; Immune complexes; Plants; Vaccine infection

Indexed keywords

DENGUE VACCINE; VIRUS ENVELOPE PROTEIN; ANTIGEN ANTIBODY COMPLEX; COMPLEMENT COMPONENT C1Q; EPITOPE; IMMUNOLOGICAL ADJUVANT; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; VIRUS ANTIBODY;

AFFINITY CHROMATOGRAPHY; ANIMAL EXPERIMENT; ANTIGEN ANTIBODY COMPLEX; ARTICLE; DENGUE; DENGUE VIRUS 2; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPRESSION VECTOR; IMMUNIZATION; IMMUNOGENICITY; MOUSE; NICOTIANA BENTHAMIANA; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; WESTERN BLOTTING; ADMINISTRATION AND DOSAGE; ANIMAL; CELL LINE; DENGUE VIRUS; EBOLAVIRUS; GEMINIVIRIDAE; GENETICS; HUMAN; HUMORAL IMMUNITY; IMMUNOLOGY; ISOLATION AND PURIFICATION; PLANT LEAF; PROCEDURES; TOBACCO; VACCINATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; ANTIGEN-ANTIBODY COMPLEX; CELL LINE; COMPLEMENT C1Q; DENGUE; DENGUE VACCINES; DENGUE VIRUS; EBOLAVIRUS; EPITOPES; GEMINIVIRIDAE; HUMANS; IMMUNITY, HUMORAL; MICE; PLANT LEAVES; TOBACCO; VACCINATION; VIRAL ENVELOPE PROTEINS;

EID: 84925335479     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2015.02.036     Document Type: Article

References (27)

1. Phoolcharoen W., Dye J.M., Kilbourne J., Piensook K., Pratt W.D., Arntzen C.J., et al. A nonreplicating subunit vaccine protects mice against lethal Ebola virus challenge. Proc Natl Acad Sci USA 2011, 108(Dec (51)):20695-20700.
2. Lam S.K. Challenges in reducing dengue burden; diagnostics, control measures and vaccines. Expert Rev Vaccines 2013, 12(Sep (9)):995-1010.
3. Beckett C.G., Tjaden J., Burgess T., Danko J.R., Tamminga C., Simmons M., et al. Evaluation of a prototype dengue-1 DNA vaccine in a Phase 1 clinical trial. Vaccine 2011, 29(Jan (5)):960-968.
4. Coller B.A., Clements D.E. Dengue vaccines: progress and challenges. Curr Opin Immunol 2011, 23(Jan (3)):391-398.
5. Danko J.R., Beckett C.G., Porter K.R. Development of dengue DNA vaccines. Vaccine 2011, 29(Sep (42)):7261-7266.
6. Guy B., Barrere B., Malinowski C., Saville M., Teyssou R., Lang J. From research to phase III: preclinical, industrial and clinical development of the Sanofi Pasteur tetravalent dengue vaccine. Vaccine 2011, 29(Sep (42)):7229-7241.
7. Lindow J.C., Durbin A.P., Whitehead S.S., Pierce K.K., Carmolli M.P., Kirkpatrick B.D. Vaccination of volunteers with low-dose, live-attenuated, dengue viruses leads to serotype-specific immunologic and virologic profiles. Vaccine 2013, 31(Jul (33)):3347-3352.
8. Murphy B.R., Whitehead S.S. Immune response to dengue virus and prospects for a vaccine. Annu Rev Immunol 2011, 29:587-619.
9. Osorio J.E., Huang C.Y., Kinney R.M., Stinchcomb D.T. Development of DENVax: a chimeric dengue-2 PDK-53-based tetravalent vaccine for protection against dengue fever. Vaccine 2011, 29(Sep (42)):7251-7260.
10. Sabchareon A., Sirivichayakul C., Limkittikul K., Chanthavanich P., Suvannadabba S., Jiwariyavej V., et al. Dengue infection in children in Ratchaburi, Thailand: a cohort study. I. Epidemiology of symptomatic acute dengue infection in children, 2006-2009. PLoS Negl Trop Dis 2012, 6(7):e1732.
11. Sabchareon A., Wallace D., Sirivichayakul C., Limkittikul K., Chanthavanich P., Suvannadabba S., et al. Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial. Lancet 2012, 380(Nov (9853)):1559-1567.
12. Sirivichayakul C., Limkittikul K., Chanthavanich P., Jiwariyavej V., Chokejindachai W., Pengsaa K., et al. Dengue infection in children in Ratchaburi, Thailand: a cohort study. II. Clinical manifestations. PLoS Negl Trop Dis 2012, 6(2):e1520.
13. Halstead S.B. Identifying protective dengue vaccines: guide to mastering an empirical process. Vaccine 2013, 31(Sep (41)):4501-4507.
14. Chen H.W., Liu S.J., Li Y.S., Liu H.H., Tsai J.P., Chiang C.Y., et al. A consensus envelope protein domain III can induce neutralizing antibody responses against serotype 2 of dengue virus in non-human primates. Arch Virol 2013, 158(7):1523-1531.
15. Chiang C.Y., Hsieh C.H., Chen M.Y., Tsai J.P., Liu H.H., Liu S.J., et al. Recombinant lipidated dengue-4 envelope protein domain III elicits protective immunity. Vaccine 2014, 32(Mar (12)):1346-1353.
16. Leng C.H., Liu S.J., Tsai J.P., Li Y.S., Chen M.Y., Liu H.H., et al. A novel dengue vaccine candidate that induces cross-neutralizing antibodies and memory immunity. Microbes Infect 2009, 11(2):288-295.
17. Hioe C.E., Visciano M.L., Kumar R., Liu J., Mack E.A., Simon R.E., et al. The use of immune complex vaccines to enhance antibody responses against neutralizing epitopes on HIV-1 envelope gp120. Vaccine 2009, 28(Dec (2)):352-360.
18. Kumar R., Tuen M., Li H., Tse D.B., Hioe C.E. Improving immunogenicity of HIV-1 envelope gp120 by glycan removal and immune complex formation. Vaccine 2011, 29(Nov (48)):9064-9074.
19. Kumar R., Tuen M., Liu J., Nadas A., Pan R., Kong X., et al. Elicitation of broadly reactive antibodies against glycan-modulated neutralizing V3 epitopes of HIV-1 by immune complex vaccines. Vaccine 2013, 31(Nov (46)):5413-5421.
20. Chargelegue D., Drake P.M., Obregon P., Prada A., Fairweather N., Ma J.K. Highly immunogenic and protective recombinant vaccine candidate expressed in transgenic plants. Infect Immun 2005, 73(9):5915-5922.
21. Phoolcharoen W., Bhoo S.H., Lai H., Ma J., Arntzen C.J., Chen Q., et al. Expression of an immunogenic Ebola immune complex in Nicotiana benthamiana. Plant Biotechnol J 2011, 9(Sep (7)):807-816.
22. Pepponi I., Diogo G.R., Stylianou E., van Dolleweerd C.J., Drake P.M., Paul M.J., et al. Plant-derived recombinant immune complexes as self-adjuvanting TB immunogens for mucosal boosting of BCG. Plant Biotechnol J 2014, 12(7):840-850.
23. Huang Z., Phoolcharoen W., Lai H., Piensook K., Cardineau G., Zeitlin L., et al. High-level rapid production of full-size monoclonal antibodies in plants by a single-vector DNA replicon system. Biotechnol Bioeng 2010, 106(May (1)):9-17.
24. Mor T.S., Moon Y.S., Palmer K.E., Mason H.S. Geminivirus vectors for high-level expression of foreign proteins in plant cells. Biotechnol Bioeng 2003, 81(Feb (4)):430-437.
25. Kim M.Y., Yang M.S., Kim T.G. Expression of a consensus dengue virus envelope protein domain III in transgenic callus of rice. Plant Cell Tissue Organ Cult 2012, 109(Jan (3)):509-515.
26. Chen Q., He J., Phoolcharoen W., Mason H.S. Geminiviral vectors based on bean yellow dwarf virus for production of vaccine antigens and monoclonal antibodies in plants. Hum Vaccin 2011, 7(3):331-338.
27. Laufs J., Jupin I., David C., Schumacher S., Heyraud-Nitschke F., Gronenborn B. Geminivirus replication: genetic and biochemical characterization of Rep protein function, a review. Biochimie 1995, 77(10):765-773.