Distribution of enterovirus 71 RNA in inflammatory cells infiltrating different tissues in fatal cases of hand, foot, and mouth disease

Archives of Virology

Volumn 160, Issue 1, 2015, Pages 81-90

  Yu, Pin ^a   Gao, Zifen ^b   Zong, Yuanyuan ^c   Bao, Linlin ^a   Xu, Lili ^a   Deng, Wei ^a   Xu, Yanfeng ^a   Gao, Zhancheng ^d   Yao, Yanfeng ^a   Li, Fengdi ^a   Lv, Qi ^a   Qin, Chuan ^a  

^a BEIJING HOSPITAL   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

^d PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

Author keywords

Enterovirus 71; Fatal clinical cases; Hand, foot, and mouth disease; In situ hybridization; Inflammatory cell

Indexed keywords

VIRUS RNA;

CELLULAR IMMUNITY; ENTEROVIRUS; HAND FOOT AND MOUTH DISEASE; HUMAN; IN SITU HYBRIDIZATION; INFLAMMATION; ISOLATION AND PURIFICATION; MORTALITY; PHYSIOLOGY; TISSUE DISTRIBUTION; VIROLOGY; VIRUS GENOME;

ENTEROVIRUS A, HUMAN; GENOME, VIRAL; HAND, FOOT AND MOUTH DISEASE; HUMANS; IMMUNITY, CELLULAR; IN SITU HYBRIDIZATION; INFLAMMATION; RNA, VIRAL; TISSUE DISTRIBUTION;

EID: 84925285491     PISSN: 03048608     EISSN: 14328798     Source Type: Journal    
DOI: 10.1007/s00705-014-2233-x     Document Type: Article

References (25)

1. Brown BA, Pallansch MA (1995) Complete nucleotide sequence of enterovirus 71 is distinct from poliovirus. Virus Res 39:195–205
2. Chan KP, Goh KT, Chong CY, Teo ES, Lau G, Ling AE (2003) Epidemic hand, foot and mouth disease caused by human enterovirus 71, Singapore. Emerg Infect Dis 9:78–85
3. Chan LG, Parashar UD, Lye MS, Ong FG, Zaki SR, Alexander JP, Ho KK, Han LL, Pallansch MA, Suleiman AB, Jegathesan M, Anderson LJ (2000) Deaths of children during an outbreak of hand, foot, and mouth disease in Sarawak, Malaysia: clinical and pathological characteristics of the disease. For the Outbreak Study Group. Clin Infect Dis 31:678–683
4. Chang LY, Huang LM, Gau SS, Wu YY, Hsia SH, Fan TY, Lin KL, Huang YC, Lu CY, Lin TY (2007) Neurodevelopment and cognition in children after enterovirus 71 infection. N Engl J Med 356:1226–1234
5. Chatproedprai S, Theanboonlers A, Korkong S, Thongmee C, Wananukul S, Poovorawan Y (2010) Clinical and molecular characterization of hand-foot-and-mouth disease in Thailand, 2008–2009. Jpn J Infect Dis 63:229–233
6. Chung PW, Huang YC, Chang LY, Lin TY, Ning HC (2001) Duration of enterovirus shedding in stool. J Microbiol Immunol Infect 34:167–170
7. Herrero LJ, Lee CS, Hurrelbrink RJ, Chua BH, Chua KB, McMinn PC (2003) Molecular epidemiology of enterovirus 71 in peninsular Malaysia, 1997–2000. Arch Virol 148:1369–1385
8. Ho M (2000) Enterovirus 71: the virus, its infections and outbreaks. J Microbiol Immunol Infect 33:205–216
9. Hsu SM, Raine L, Fanger H (1981) Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 29:577–580
10. Hsueh C, Jung SM, Shih SR, Kuo TT, Shieh WJ, Zaki S, Lin TY, Chang LY, Ning HC, Yen DC (2000) Acute encephalomyelitis during an outbreak of enterovirus type 71 infection in Taiwan: report of an autopsy case with pathologic, immunofluorescence, and molecular studies. Mod Pathol 13:1200–1205
11. Huang CC, Liu CC, Chang YC, Chen CY, Wang ST, Yeh TF (1999) Neurologic complications in children with enterovirus 71 infection. N Engl J Med 341:936–942
12. Jiang M, Wei D, Ou WL, Li KX, Luo DZ, Li YQ, Chen E, Nong GM (2012) Autopsy findings in children with hand, foot, and mouth disease. N Engl J Med 367:91–92
13. Li L, He Y, Yang H, Zhu J, Xu X, Dong J, Zhu Y, Jin Q (2005) Genetic characteristics of human enterovirus 71 and coxsackievirus A16 circulating from 1999 to 2004 in Shenzhen, People’s Republic of China. J Clin Microbiol 43:3835–3839
14. Lum LC, Wong KT, Lam SK, Chua KB, Goh AY, Lim WL, Ong BB, Paul G, AbuBakar S, Lambert M (1998) Fatal enterovirus 71 encephalomyelitis. J Pediatr 133:795–798
15. McMinn P, Lindsay K, Perera D, Chan HM, Chan KP, Cardosa MJ (2001) Phylogenetic analysis of enterovirus 71 strains isolated during linked epidemics in Malaysia, Singapore, and Western Australia. J Virol 75:7732–7738
16. Schmidt NJ, Lennette EH, Ho HH (1974) An apparently new enterovirus isolated from patients with disease of the central nervous system. J Infect Dis 129:304–309
17. Solomon T, Lewthwaite P, Perera D, Cardosa MJ, McMinn P, Ooi MH (2010) Virology, epidemiology, pathogenesis, and control of enterovirus 71. Lancet Infect Dis 10:778–790
18. Tu PV, Thao NT, Perera D, Huu TK, Tien NT, Thuong TC, How OM, Cardosa MJ, McMinn PC (2007) Epidemiologic and virologic investigation of hand, foot, and mouth disease, southern Vietnam, 2005. Emerg Infect Dis 13:1733–1741
19. Wang JR, Tuan YC, Tsai HP, Yan JJ, Liu CC, Su IJ (2002) Change of major genotype of enterovirus 71 in outbreaks of hand-foot-and-mouth disease in Taiwan between 1998 and 2000. J Clin Microbiol 40:10–15
20. Wong SS, Yip CC, Lau SK, Yuen KY (2010) Human enterovirus 71 and hand, foot and mouth disease. Epidemiol Infect 138:1071–1089
21. Xing W, Liao Q, Viboud C, Zhang J, Sun J, Wu JT, Chang Z, Liu F, Fang VJ, Zheng Y, Cowling BJ, Varma JK, Farrar JJ, Leung GM, Yu H (2014) Hand, foot, and mouth disease in China, 2008–12: an epidemiological study. Lancet Infect Dis 14:308–318
22. Yang Y, Wang H, Gong E, Du J, Zhao X, McNutt MA, Wang S, Zhong Y, Gao Z, Zheng J (2009) Neuropathology in 2 cases of fatal enterovirus type 71 infection from a recent epidemic in the People’s Republic of China: a histopathologic, immunohistochemical, and reverse transcription polymerase chain reaction study. Hum Pathol 40:1288–1295
23. Yu P, Gao Z, Zong Y, Bao L, Xu L, Deng W, Li F, Lv Q, Xu Y, Yao Y, Qin C (2014) Histopathological features and distribution of EV71 antigens and SCARB2 in human fatal cases and a mouse model of enterovirus 71 infection. Virus Res 189C:121–132
24. Zhang Y, Tan XJ, Wang HY, Yan DM, Zhu SL, Wang DY, Ji F, Wang XJ, Gao YJ, Chen L, An HQ, Li DX, Wang SW, Xu AQ, Wang ZJ, Xu WB (2009) An outbreak of hand, foot, and mouth disease associated with subgenotype C4 of human enterovirus 71 in Shandong, China. J Clin Virol 44:262–267
25. Zhang Y, Zhu Z, Yang W, Ren J, Tan X, Wang Y, Mao N, Xu S, Zhu S, Cui A, Yan D, Li Q, Dong X, Zhang J, Zhao Y, Wan J, Feng Z, Sun J, Wang S, Li D, Xu W (2010) An emerging recombinant human enterovirus 71 responsible for the 2008 outbreak of hand foot and mouth disease in Fuyang city of China. Virol J 7:94