-
1
-
-
84860679595
-
Asthma phenotypes: The evolution from clinical to molecular approaches
-
Wenzel SE (2012) Asthma phenotypes: The evolution from clinical to molecular approaches. Nat Med 18: 716-725.
-
(2012)
Nat Med
, vol.18
, pp. 716-725
-
-
Wenzel, S.E.1
-
2
-
-
84860691114
-
The airway epithelium in asthma
-
Lambrecht BN, Hammad H (2012) The airway epithelium in asthma. Nat Med 18: 684-692.
-
(2012)
Nat Med
, vol.18
, pp. 684-692
-
-
Lambrecht, B.N.1
Hammad, H.2
-
3
-
-
79959369140
-
The sentinel role of the airway epithelium in asthma pathogenesis
-
Holgate ST (2011) The sentinel role of the airway epithelium in asthma pathogenesis. Immunol Rev 242: 205-219.
-
(2011)
Immunol Rev
, vol.242
, pp. 205-219
-
-
Holgate, S.T.1
-
4
-
-
0029820378
-
Allergen-specific IgE levels and mite allergen exposure in children with acute asthma first seen in an emergency department and in nonasthmatic control subjects
-
Nelson RP Jr, DiNicolo R, Fernandez-Caldas E, Seleznick MJ, Lockey RF, et al. (1996) Allergen-specific IgE levels and mite allergen exposure in children with acute asthma first seen in an emergency department and in nonasthmatic control subjects. J Allergy Clin Immunol 98: 258-263. (Pubitemid 26326118)
-
(1996)
Journal of Allergy and Clinical Immunology
, vol.98
, Issue.2
, pp. 258-263
-
-
Nelson Jr., R.P.1
DiNicolo, R.2
Fernandez-Caldas, E.3
Seleznick, M.J.4
Lockey, R.F.5
Good, R.A.6
-
5
-
-
80051930931
-
Orchestrating house dust mite-associated allergy in the lung
-
Gregory LG, Lloyd CM (2011) Orchestrating house dust mite-associated allergy in the lung. Trends Immunol 32: 402-411.
-
(2011)
Trends Immunol
, vol.32
, pp. 402-411
-
-
Gregory, L.G.1
Lloyd, C.M.2
-
6
-
-
79955062468
-
Alternaria alternata serine proteases induce lung inflammation and airway epithelial cell activation via PAR2
-
Boitano S, Flynn AN, Sherwood CL, Schulz SM, Hoffman J, et al. (2011) Alternaria alternata serine proteases induce lung inflammation and airway epithelial cell activation via PAR2. Am J Physiol Lung Cell Mol Physiol 300: L605-14.
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.300
-
-
Boitano, S.1
Flynn, A.N.2
Sherwood, C.L.3
Schulz, S.M.4
Hoffman, J.5
-
7
-
-
47349102541
-
Mite and cockroach allergens activate protease-activated receptor 2 and delay epidermal permeability barrier recovery
-
DOI 10.1038/jid.2008.13, PII JID200813
-
Jeong SK, Kim HJ, Youm JK, Ahn SK, Choi EH, et al. (2008) Mite and cockroach allergens activate protease-activated receptor 2 and delay epidermal permeability barrier recovery. J Invest Dermatol 128: 1930-1939. (Pubitemid 352001196)
-
(2008)
Journal of Investigative Dermatology
, vol.128
, Issue.8
, pp. 1930-1939
-
-
Jeong, S.K.1
Kim, H.J.2
Youm, J.-K.3
Ahn, S.K.4
Choi, E.H.5
Sohn, M.H.6
Kim, K.-E.7
Hong, J.H.8
Shin, D.M.9
Lee, S.H.10
-
8
-
-
64149087970
-
House dust mite allergen induces asthma via toll-like receptor 4 triggering of airway structural cells
-
Hammad H, Chieppa M, Perros F, Willart MA, Germain RN, et al. (2009) House dust mite allergen induces asthma via toll-like receptor 4 triggering of airway structural cells. Nat Med 15: 410-416.
-
(2009)
Nat Med
, vol.15
, pp. 410-416
-
-
Hammad, H.1
Chieppa, M.2
Perros, F.3
Willart, M.A.4
Germain, R.N.5
-
9
-
-
61549104474
-
Innate immune responses of airway epithelium to house dust mite are mediated through beta-glucan-dependent pathways
-
Nathan AT, Peterson EA, Chakir J, Wills-Karp M (2009) Innate immune responses of airway epithelium to house dust mite are mediated through beta-glucan-dependent pathways. J Allergy Clin Immunol 123: 612-618.
-
(2009)
J Allergy Clin Immunol
, vol.123
, pp. 612-618
-
-
Nathan, A.T.1
Peterson, E.A.2
Chakir, J.3
Wills-Karp, M.4
-
10
-
-
0033545627
-
A protective role for protease-activated receptors in the airways
-
Cocks TM, Fong B, Chow JM, Anderson GP, Frauman AG, et al. (1999) A protective role for protease-activated receptors in the airways. Nature 398: 156-160.
-
(1999)
Nature
, vol.398
, pp. 156-160
-
-
Cocks, T.M.1
Fong, B.2
Chow, J.M.3
Anderson, G.P.4
Frauman, A.G.5
-
11
-
-
0035184146
-
Protease-activated receptors in human airways: Upregulation of PAR-2 in respiratory epithelium from patients with asthma
-
DOI 10.1067/mai.2001.119025
-
Knight DA, Lim S, Scaffidi AK, Roche N, Chung KF, et al. (2001) Protease-activated receptors in human airways: Upregulation of PAR-2 in respiratory epithelium from patients with asthma. J Allergy Clin Immunol 108: 797-803. (Pubitemid 33096213)
-
(2001)
Journal of Allergy and Clinical Immunology
, vol.108
, Issue.5
, pp. 797-803
-
-
Knight, D.A.1
Lim, S.2
Scaffidi, A.K.3
Roche, N.4
Chung K.Fan5
Stewart, G.A.6
Thompson, P.J.7
-
12
-
-
14844290334
-
Proteinase-activated receptor 2 activation in the airways enhances antigen-mediated airway inflammation and airway hyperresponsiveness through different pathways
-
DOI 10.1016/j.jaci.2004.11.042
-
Ebeling C, Forsythe P, Ng J, Gordon JR, Hollenberg M, et al. (2005) Proteinase-activated receptor 2 activation in the airways enhances antigen-mediated airway inflammation and airway hyperresponsiveness through different pathways. J Allergy Clin Immunol 115: 623-630. (Pubitemid 40341720)
-
(2005)
Journal of Allergy and Clinical Immunology
, vol.115
, Issue.3
, pp. 623-630
-
-
Ebeling, C.1
Forsythe, P.2
Ng, J.3
Gordon, J.R.4
Hollenberg, M.5
Vliagoftis, H.6
-
13
-
-
33745074367
-
House dust mite major allergens der p 1 and der p 5 activate human airway-derived epithelial cells by protease-dependent and protease-independent mechanisms
-
Kauffman HF, Tamm M, Timmerman JA, Borger P (2006) House dust mite major allergens der p 1 and der p 5 activate human airway-derived epithelial cells by protease-dependent and protease-independent mechanisms. Clin Mol Allergy 4: 5.
-
(2006)
Clin Mol Allergy
, vol.4
, pp. 5
-
-
Kauffman, H.F.1
Tamm, M.2
Timmerman, J.A.3
Borger, P.4
-
14
-
-
0037108373
-
House dust mite allergens induce proinflammatory cytokines from respiratory epithelial cells: The cysteine protease allergen, Der p 1, activates protease-activated receptor (PAR)-2 and inactivates PAR-1
-
Asokananthan N, Graham PT, Stewart DJ, Bakker AJ, Eidne KA, et al. (2002) House dust mite allergens induce proinflammatory cytokines from respiratory epithelial cells: The cysteine protease allergen, der p 1, activates protease-activated receptor (PAR)-2 and inactivates PAR-1. J Immunol 169: 4572-4578. (Pubitemid 35178236)
-
(2002)
Journal of Immunology
, vol.169
, Issue.8
, pp. 4572-4578
-
-
Asokananthan, N.1
Graham, P.T.2
Stewart, D.J.3
Bakker, A.J.4
Eidne, K.A.5
Thompson, P.J.6
Stewart, G.A.7
-
15
-
-
38449122657
-
Proteinase-activated receptor-2 promotes allergic sensitization to an inhaled antigen through a TNF-mediated pathway
-
Ebeling C, Lam T, Gordon JR, Hollenberg MD, Vliagoftis H (2007) Proteinase-activated receptor-2 promotes allergic sensitization to an inhaled antigen through a TNF-mediated pathway. J Immunol 179: 2910-2917.
-
(2007)
J Immunol
, vol.179
, pp. 2910-2917
-
-
Ebeling, C.1
Lam, T.2
Gordon, J.R.3
Hollenberg, M.D.4
Vliagoftis, H.5
-
16
-
-
0036840959
-
Protease-activated receptor 2 mediates eosinophil infiltration and hyperreactivity in allergic inflammation of the airway
-
Schmidlin F, Amadesi S, Dabbagh K, Lewis DE, Knott P, et al. (2002) Protease-activated receptor 2 mediates eosinophil infiltration and hyperreactivity in allergic inflammation of the airway. J Immunol 169: 5315-5321. (Pubitemid 35217205)
-
(2002)
Journal of Immunology
, vol.169
, Issue.9
, pp. 5315-5321
-
-
Schmidlin, F.1
Amadesi, S.2
Dabbagh, K.3
Lewis, D.E.4
Knott, P.5
Bunnett, N.W.6
Gater, P.R.7
Geppetti, P.8
Bertrand, C.9
Stevens, M.E.10
-
17
-
-
84861883125
-
The composition of house dust mite is critical for mucosal barrier dysfunction and allergic sensitisation
-
Post S, Nawijn MC, Hackett TL, Baranowska M, Gras R, et al. (2012) The composition of house dust mite is critical for mucosal barrier dysfunction and allergic sensitisation. Thorax 67: 488-495.
-
(2012)
Thorax
, vol.67
, pp. 488-495
-
-
Post, S.1
Nawijn, M.C.2
Hackett, T.L.3
Baranowska, M.4
Gras, R.5
-
18
-
-
45149085743
-
Strain-specific requirement for eosinophils in the recruitment of T cells to the lung during the development of allergic asthma
-
DOI 10.1084/jem.20071836
-
Walsh ER, Sahu N, Kearley J, Benjamin E, Kang BH, et al. (2008) Strain-specific requirement for eosinophils in the recruitment of T cells to the lung during the development of allergic asthma. J Exp Med 205: 1285-1292. (Pubitemid 351831486)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.6
, pp. 1285-1292
-
-
Walsh, E.R.1
Sahu, N.2
Kearley, J.3
Benjamin, E.4
Boo, H.K.5
Humbles, A.6
August, A.7
-
19
-
-
34250159407
-
Down-regulation of E-cadherin in human bronchial epithelial cells leads to epidermal growth factor receptor-dependent Th2 cell-promoting activity
-
Heijink IH, Kies PM, Kauffman HF, Postma DS, van Oosterhout AJ, et al. (2007) Down-regulation of E-cadherin in human bronchial epithelial cells leads to epidermal growth factor receptor-dependent Th2 cell-promoting activity. J Immunol 178: 7678-7685. (Pubitemid 46898038)
-
(2007)
Journal of Immunology
, vol.178
, Issue.12
, pp. 7678-7685
-
-
Heijink, I.H.1
Kies, P.M.2
Kauffman, H.F.3
Postma, D.S.4
Van Oosterhout, A.J.M.5
Vellenga, E.6
-
20
-
-
20444365526
-
Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity
-
Ying S, O'Connor B, Ratoff J, Meng Q, Mallett K, et al. (2005) Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity. J Immunol 174: 8183-8190. (Pubitemid 40806330)
-
(2005)
Journal of Immunology
, vol.174
, Issue.12
, pp. 8183-8190
-
-
Ying, S.1
O'Connor, B.2
Ratoff, J.3
Meng, Q.4
Mallett, K.5
Cousins, D.6
Robinson, D.7
Zhang, G.8
Zhao, J.9
Lee, T.H.10
Corrigan, C.11
-
21
-
-
84861854150
-
Mucosal exposure to cockroach extract induces allergic sensitization and allergic airway inflammation
-
Arizmendi NG, Abel M, Puttagunta L, Asaduzzaman M, Davidson C, et al. (2011) Mucosal exposure to cockroach extract induces allergic sensitization and allergic airway inflammation. Allergy Asthma Clin Immunol 7: 22.
-
(2011)
Allergy Asthma Clin Immunol
, vol.7
, pp. 22
-
-
Arizmendi, N.G.1
Abel, M.2
Puttagunta, L.3
Asaduzzaman, M.4
Davidson, C.5
-
22
-
-
33751506710
-
Interleukin-17 is a negative regulator of established allergic asthma
-
DOI 10.1084/jem.20061401
-
Schnyder-Candrian S, Togbe D, Couillin I, Mercier I, Brombacher F, et al. (2006) Interleukin-17 is a negative regulator of established allergic asthma. J Exp Med 203: 2715-2725. (Pubitemid 44833347)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.12
, pp. 2715-2725
-
-
Schnyder-Candrian, S.1
Togbe, D.2
Couillin, I.3
Mercier, I.4
Brombacher, F.5
Quesniaux, V.6
Fossiez, F.7
Ryffel, B.8
Schnyder, B.9
-
23
-
-
0019505760
-
Inhibition of specific IgE responses in mice by pre-exposure to inhaled antigen
-
Holt PG, Batty JE, Turner KJ (1981) Inhibition of specific IgE responses in mice by pre-exposure to inhaled antigen. Immunology 42: 409-417. (Pubitemid 11094416)
-
(1981)
Immunology
, vol.42
, Issue.3
, pp. 409-417
-
-
Holt, P.G.1
Batty, J.E.2
Turner, K.J.3
-
24
-
-
0043123373
-
Proteolytic activity of the house dust mite allergen Der p 1 enhances allergenicity in a mouse inhalation model
-
DOI 10.1046/j.1365-2222.2003.01716.x
-
Gough L, Campbell E, Bayley D, Van Heeke G, Shakib F (2003) Proteolytic activity of the house dust mite allergen der p 1 enhances allergenicity in a mouse inhalation model. Clin Exp Allergy 33: 1159-1163. (Pubitemid 36976244)
-
(2003)
Clinical and Experimental Allergy
, vol.33
, Issue.8
, pp. 1159-1163
-
-
Gough, L.1
Campbell, E.2
Bayley, D.3
Van Heeke, G.4
Shakib, F.5
-
25
-
-
33646368158
-
The house dust mite allergen Der p 1, unlike Der p 3, stimulates the expression of interleukin-8 in human airway epithelial cells via a proteinase-activated receptor-2-independent mechanism
-
DOI 10.1074/jbc.M507140200
-
Adam E, Hansen KK, Astudillo Fernandez O, Coulon L, Bex F, et al. (2006) The house dust mite allergen der p 1, unlike der p 3, stimulates the expression of interleukin-8 in human airway epithelial cells via a proteinase-activated receptor-2-independent mechanism. J Biol Chem 281: 6910-6923. (Pubitemid 43847453)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.11
, pp. 6910-6923
-
-
Adam, E.1
Hansen, K.K.2
Astudillo, O.F.3
Coulon, L.4
Bex, F.5
Duhant, X.6
Jaumotte, E.7
Hollenberg, M.D.8
Jacquet, A.9
-
26
-
-
67650450510
-
The non-proteolytic house dust mite allergen der p 2 induce NF-kappaB and MAPK dependent activation of bronchial epithelial cells
-
Osterlund C, Gronlund H, Polovic N, Sundstrom S, Gafvelin G, et al. (2009) The non-proteolytic house dust mite allergen der p 2 induce NF-kappaB and MAPK dependent activation of bronchial epithelial cells. Clin Exp Allergy 39: 1199-1208.
-
(2009)
Clin Exp Allergy
, vol.39
, pp. 1199-1208
-
-
Osterlund, C.1
Gronlund, H.2
Polovic, N.3
Sundstrom, S.4
Gafvelin, G.5
-
27
-
-
54049117260
-
Analysis of proteinase-activated receptor 2 and TLR4 signal transduction: A novel paradigm for receptor cooperativity
-
Rallabhandi P, Nhu QM, Toshchakov VY, Piao W, Medvedev AE, et al. (2008) Analysis of proteinase-activated receptor 2 and TLR4 signal transduction: A novel paradigm for receptor cooperativity. J Biol Chem 283: 24314-24325.
-
(2008)
J Biol Chem
, vol.283
, pp. 24314-24325
-
-
Rallabhandi, P.1
Nhu, Q.M.2
Toshchakov, V.Y.3
Piao, W.4
Medvedev, A.E.5
-
28
-
-
80051573599
-
Purinergic receptor type 6 contributes to airway inflammation and remodeling in experimental allergic airway inflammation
-
Vieira RP, Muller T, Grimm M, von Gernler V, Vetter B, et al. (2011) Purinergic receptor type 6 contributes to airway inflammation and remodeling in experimental allergic airway inflammation. Am J Respir Crit Care Med 184: 215-223.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 215-223
-
-
Vieira, R.P.1
Muller, T.2
Grimm, M.3
Von Gernler, V.4
Vetter, B.5
-
29
-
-
0036754255
-
Antigen-specific T cell sensitization is impaired in Il-17-deficient mice, causing suppression of allergic cellular and humoral responses
-
DOI 10.1016/S1074-7613(02)00391-6
-
Nakae S, Komiyama Y, Nambu A, Sudo K, Iwase M, et al. (2002) Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity 17: 375-387. (Pubitemid 35279557)
-
(2002)
Immunity
, vol.17
, Issue.3
, pp. 375-387
-
-
Nakae, S.1
Komiyama, Y.2
Nambu, A.3
Sudo, K.4
Iwase, M.5
Homma, I.6
Sekikawa, K.7
Asano, M.8
Iwakura, Y.9
-
30
-
-
80052963798
-
Reciprocal expression of IL-25 and IL-17A is important for allergic airways hyperreactivity
-
Barlow JL, Flynn RJ, Ballantyne SJ, McKenzie AN (2011) Reciprocal expression of IL-25 and IL-17A is important for allergic airways hyperreactivity. Clin Exp Allergy 41: 1447-1455.
-
(2011)
Clin Exp Allergy
, vol.41
, pp. 1447-1455
-
-
Barlow, J.L.1
Flynn, R.J.2
Ballantyne, S.J.3
McKenzie, A.N.4
-
31
-
-
70349120838
-
Inhaled house dust mite induces pulmonary T helper 2 cytokine production
-
Gregory LG, Causton B, Murdoch JR, Mathie SA, O'Donnell V, et al. (2009) Inhaled house dust mite induces pulmonary T helper 2 cytokine production. Clin Exp Allergy 39: 1597-1610.
-
(2009)
Clin Exp Allergy
, vol.39
, pp. 1597-1610
-
-
Gregory, L.G.1
Causton, B.2
Murdoch, J.R.3
Mathie, S.A.4
O'Donnell, V.5
-
32
-
-
80053174196
-
Protease-activated receptor 2 activation of myeloid dendritic cells regulates allergic airway inflammation
-
Lewkowich IP, Day SB, Ledford JR, Zhou P, Dienger K, et al. (2011) Protease-activated receptor 2 activation of myeloid dendritic cells regulates allergic airway inflammation. Respir Res 12: 122.
-
(2011)
Respir Res
, vol.12
, pp. 122
-
-
Lewkowich, I.P.1
Day, S.B.2
Ledford, J.R.3
Zhou, P.4
Dienger, K.5
-
33
-
-
83555164860
-
German cockroach proteases and protease-activated receptor-2 regulate chemokine production and dendritic cell recruitment
-
Day SB, Ledford JR, Zhou P, Lewkowich IP, Page K (2012) German cockroach proteases and protease-activated receptor-2 regulate chemokine production and dendritic cell recruitment. J Innate Immun 4: 100-110.
-
(2012)
J Innate Immun
, vol.4
, pp. 100-110
-
-
Day, S.B.1
Ledford, J.R.2
Zhou, P.3
Lewkowich, I.P.4
Page, K.5
-
34
-
-
77956669276
-
Mucosal sensitization to german cockroach involves protease-activated receptor-2
-
Page K, Ledford JR, Zhou P, Dienger K, Wills-Karp M (2010) Mucosal sensitization to german cockroach involves protease-activated receptor-2. Respir Res 11: 62.
-
(2010)
Respir Res
, vol.11
, pp. 62
-
-
Page, K.1
Ledford, J.R.2
Zhou, P.3
Dienger, K.4
Wills-Karp, M.5
-
35
-
-
73549099955
-
Straindependent activation of NF-kappaB in the airway epithelium and its role in allergic airway inflammation
-
Alcorn JF, Ckless K, Brown AL, Guala AS, Kolls JK, et al. (2010) Straindependent activation of NF-kappaB in the airway epithelium and its role in allergic airway inflammation. Am J Physiol Lung Cell Mol Physiol 298: L57-66.
-
(2010)
Am J Physiol Lung Cell Mol Physiol
, vol.298
-
-
Alcorn, J.F.1
Ckless, K.2
Brown, A.L.3
Guala, A.S.4
Kolls, J.K.5
-
36
-
-
84890391893
-
Epithelial NF-kappaB orchestrates house dust mite-induced airway inflammation, hyperresponsiveness, and fibrotic remodeling
-
Tully JE, Hoffman SM, Lahue KG, Nolin JD, Anathy V, et al. (2013) Epithelial NF-kappaB orchestrates house dust mite-induced airway inflammation, hyperresponsiveness, and fibrotic remodeling. J Immunol 191: 5811-5821.
-
(2013)
J Immunol
, vol.191
, pp. 5811-5821
-
-
Tully, J.E.1
Hoffman, S.M.2
Lahue, K.G.3
Nolin, J.D.4
Anathy, V.5
|