Probable warfarin interaction with menthol cough drops

Pharmacotherapy

Volumn 30, Issue 1, 2010, Pages

  Coderre, Karen ^a   Faria, Claudio ^a   Dyer, Earl ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Cough drop; Menthol; Warfarin

Indexed keywords

MENTHOL; WARFARIN; ANTICOAGULANT AGENT; NON PRESCRIPTION DRUG;

ADULT; ARTICLE; CASE REPORT; DRUG DOSE INCREASE; DRUG EFFECT; FOOD DRUG INTERACTION; HUMAN; HYPERTENSION; INTERNATIONAL NORMALIZED RATIO; MALE; MEDICAL HISTORY; MIDDLE AGED; OUTCOME ASSESSMENT; SLEEP DISORDERED BREATHING; VENOUS THROMBOEMBOLISM; AFRICAN AMERICAN; COUGHING; DRUG INTERACTION;

AFRICAN AMERICANS; ANTICOAGULANTS; COUGH; DRUG INTERACTIONS; HUMANS; INTERNATIONAL NORMALIZED RATIO; MALE; MENTHOL; MIDDLE AGED; NONPRESCRIPTION DRUGS; VENOUS THROMBOEMBOLISM; WARFARIN;

EID: 84925269975     PISSN: 02770008     EISSN: 18759114     Source Type: Journal    
DOI: 10.1592/phco.30.1.110     Document Type: Article

References (6)

1. Holbrook AM, Pereira JA, Labiris R, McDonald H, Douketis JD, Crowther M, et al. Systemic Overview of Warfarin and Its Drug and Food Interactions. Arch Intern Med 2005;165:1095-1106.
2. Kassebaum PJ, Shaw DL, Tomich DJ. Possible Warfarin Interaction with Menthol Cough Drops. Ann Pharmacother 2005;39:365-7.
3. Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-45.
4. Madyastha KM, Srivatsan V. Studies on the metabolism of l-menthol in rats. Drug Metab Dispos 1988;16:765-62.
5. De-Olivera ACAX, Fidalgo-Neto AA, Paumgartten FJR. In vitro inhibition of liver monooxygneases by B-ionone, 1,9-cineole, (-)-menthol and terpinol. Toxicology 1999;135:33-41.
6. Dresser GK, Wacher V, Wong S, Wong HT, Bailer DG. Evaluation of peppermint oil and ascorbyl palmitate as inhibitors of cytochrome P4503A4 activity in vitro and in vivo. Clin Pharmacol Ther 2002;72:247-55.