Reduced primary care respiratory infection visits following pregnancy and infancy vitamin D supplementation: A randomised controlled trial

Acta Paediatrica, International Journal of Paediatrics

Volumn 104, Issue 4, 2015, Pages 396-404

  Grant, Cameron C ^a   Kaur, Suhina ^a   Waymouth, Ellen ^a   Mitchell, Edwin A ^a   Scragg, Robert ^a   Ekeroma, Alec ^a   Stewart, Alistair ^a   Crane, Julian ^b   Trenholme, Adrian ^c   Camargo, Carlos A ^d  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c MIDDLEMORE HOSPITAL   (New Zealand)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Child; Clinical trial; Pregnancy; Respiratory tract infections; Vitamin D

Indexed keywords

COLECALCIFEROL; PLACEBO; VITAMIN; VITAMIN D;

ADULT; ARTICLE; BIRTH; CHILD; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG MEGADOSE; FEMALE; GESTATIONAL AGE; HUMAN; INFANT; INFECTION PREVENTION; LOW DRUG DOSE; MAJOR CLINICAL STUDY; NEW ZEALAND; NEWBORN; NUTRITIONAL STATUS; PREGNANCY; PREGNANT WOMAN; PRESCHOOL CHILD; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT INFECTION; VITAMIN SUPPLEMENTATION; ACUTE DISEASE; DIET SUPPLEMENTATION; PRIMARY HEALTH CARE; RESPIRATORY TRACT INFECTIONS; UTILIZATION;

ACUTE DISEASE; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; PREGNANCY; PRIMARY HEALTH CARE; RESPIRATORY TRACT INFECTIONS; VITAMIN D; VITAMINS;

EID: 84925260661     PISSN: 08035253     EISSN: 16512227     Source Type: Journal    
DOI: 10.1111/apa.12819     Document Type: Article

References (30)

1. Jolliffe DA, Griffiths CJ, Martineau AR,. Vitamin D in the prevention of acute respiratory infection: systematic review of clinical studies. J Steroid Biochem Mol Biol 2013; 136: 321-9.
2. Muhe L, Lulseged S, Mason KE, Simoes EA,. Case-control study of the role of nutritional rickets in the risk of developing pneumonia in Ethiopian children. Lancet 1997; 349: 1801-4.
3. Wayse V, Yousafzai A, Mogale K, Filteau S,. Association of subclinical vitamin D deficiency with severe acute lower respiratory infection in Indian children under 5 y. Eur J Clin Nutr 2004; 58: 563-7.
4. Manaseki-Holland S, Maroof Z, Bruce J, Mughal MZ, Masher MI, Bhutta ZA, et al. Effect on the incidence of pneumonia of vitamin D supplementation by quarterly bolus dose to infants in Kabul: a randomised controlled superiority trial. Lancet 2012; 379: 1419-27.
5. Kumar GT, Sachdev HS, Chellani H, Rehman AM, Singh V, Arora H, et al. Effect of weekly vitamin D supplements on mortality, morbidity, and growth of low birthweight term infants in India up to age 6 months: randomised controlled trial. BMJ 2011; 342: d2975.
6. Bergman P, Lindh AU, Bjorkhem-Bergman l, Lindh JD,. Vitamin D and respiratory tract infections: a systematic review and meta-analysis of randomized controlled trials. PLoS One [Electronic Resource] 2013; 8: e65835.
7. Kimball S, Vieth R, Dosch HM, Bar-Or A, Cheung R, Gagne D, et al. Cholecalciferol plus calcium suppresses abnormal PBMC reactivity in patients with multiple sclerosis. J Clin Endocrinol Metab 2011; 96: 2826-34.
8. Black RE, Allen LH, Bhutta ZA, Caulfield LE, de Onis M, Ezzati M, et al. Maternal and child undernutrition: global and regional exposures and health consequences. Lancet 2008; 371: 243-60.
9. Grant CC, Wall CR, Gibbons MJ, Morton SM, Santosham M, Black RE,. Child nutrition and lower respiratory tract disease burden in New Zealand: A global context for a national perspective. J Paediatr Child Health 2011; 47: 497-504.
10. Grant CC, Wall CR, Crengle S, Scragg R,. Vitamin D deficiency in early childhood: prevalent in the sunny South Pacific. Public Health Nutr 2009; 12: 1893-901.
11. Camargo CA Jr, Ingham T, Wickens K, Thadhani RI, Silvers KM, Epton MJ, et al. Vitamin D status of newborns in New Zealand. Br J Nutr 2010; 104: 1051-7.
12. Grant CC, Stewart AW, Scragg R, Milne T, Rowden J, Ekeroma A, et al. Vitamin D during pregnancy and infancy and infant serum 25-hydroxyvitamin D concentration. Pediatrics 2014; 133: e143-53.
13. Ministry of Health. Companion statement on vitamin D and sun exposure in pregnancy and infancy in New Zealand. Wellington: Ministry of Health, 2013.
14. Vieth R,. Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety. Am J Clin Nutr 1999; 69: 842-56.
15. National Health Board Business Unit. National minimum dataset (hospital events) data dictionary. Wellington: Ministry of Health, 2010.
16. Laupacis A, Sackett DL, Roberts RS,. An assessment of clinically useful measures of the consequences of treatment. N Engl J Med 1988; 318: 1728-33.
17. Urashima M, Segawa T, Okazaki M, Kurihara M, Wada Y, Ida H,. Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren. Am J Clin Nutr 2010; 91: 1255-60.
18. Camargo CA Jr, Ganmaa D, Frazier AL, Kirchberg FF, Stuart JJ, Kleinman K, et al. Randomized trial of vitamin D supplementation and risk of acute respiratory infection in Mongolia. Pediatrics 2012; 130: e561-7.
19. Goldring ST, Griffiths CJ, Martineau AR, Robinson S, Yu C, Poulton S, et al. Prenatal vitamin D supplementation and child respiratory health: a randomised controlled trial. PLoS One [Electronic Resource] 2013; 8: e66627.
20. Manaseki-Holland S, Qader G, Isaq Masher M, Bruce J, Zulf Mughal M, Chandramohan D, et al. Effects of vitamin D supplementation to children diagnosed with pneumonia in Kabul: a randomised controlled trial. Trop Med Int Health 2010; 15: 1148-55.
21. Roth DE, Jones AB, Prosser C, Robinson JL, Vohra S,. Vitamin D receptor polymorphisms and the risk of acute lower respiratory tract infection in early childhood. J Infect Dis 2008; 197: 676-80.
22. Martineau AR, Timms PM, Bothamley GH, Hanifa Y, Islam K, Claxton AP, et al. High-dose vitamin D3 during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial. Lancet 2011; 377: 242-50.
23. Zosky GR, Berry LJ, Elliot JG, James AL, Gorman S, Hart PH,. Vitamin D deficiency causes deficits in lung function and alters lung structure. Am J Respir Crit Care Med 2011; 183: 1336-43.
24. Gaultier C, Harf A, Balmain N, Cuisinier-Gleizes P, Mathieu H,. Lung mechanics in rachitic rats. Am Rev Respir Dis 1984; 130: 1108-10.
25. Abu-Mouch S, Fireman Z, Jarchovsky J, Zeina AR, Assy N,. Vitamin D supplementation improves sustained virologic response in chronic hepatitis C (genotype 1)-naive patients. World J Gastroenterol 2011; 17: 5184-90.
26. Australian Government Department of Health and Ageing, National Health and Medical Research Council, New Zealand Ministry of Health. Nutrient reference values for Australia and New Zealand including recommended dietary intakes. Canberra: Commonwealth of Australia, 2006.
27. Scientific Advisory Committee on Nutrition. Update on vitamin D. Position statement by the Scientific Advisory Committee on Nutrition. London: The Stationery Office, 2007.
28. Doets EL, de Wit LS, Dhonukshe-Rutten RA, Cavelaars AE, Raats MM, Timotijevic L, et al. Current micronutrient recommendations in Europe: towards understanding their differences and similarities. Eur J Nutr 2008; 47 (Suppl 1): 17-40.
29. Institute of Medicine. Dietary reference intakes for calcium and vitamin D. Washington, DC: The National Academies Press, 2011.
30. Wagner CL, Greer FR,. American Acaemy of Pediatrics Section on Breastfeeding and Committee on Nutrition. Prevention of rickets and vitamin D deficiency in infants, children, and adolescents. Pediatrics 2008; 122: 1142-52.