Statins do not protect against cancer: Quite the opposite

Journal of Clinical Oncology

Volumn 33, Issue 7, 2015, Pages 810-811

  Ravnskov, Uffe ^a   Rosch, Paul J ^b   McCully, Kilmer S ^c,d  

^a New York Medical College American Institute of Stress ^*  (Sweden)

^b NEW YORK MEDICAL COLLEGE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

CANCER MORTALITY; CHOLESTEROL BLOOD LEVEL; HUMAN; LETTER; NEOPLASM; PRIMARY PREVENTION; PRIORITY JOURNAL; COLORECTAL NEOPLASMS; FEMALE; HEALTH SURVEY; MALE; PROCEDURES; REGISTER; STATISTICS AND NUMERICAL DATA;

COLORECTAL NEOPLASMS; FEMALE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MALE; POPULATION SURVEILLANCE; REGISTRIES;

EID: 84925255422     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2014.58.9564     Document Type: Letter

References (10)

1. Cardwell CR, Hicks BM, Hughes C, et al: Statin use after colorectal cancer diagnosis and survival: A population-based cohort study. J Clin Oncol 32:3177-3183, 2014
2. Ravnskov U, Rosch PJ, McCully KS: The statin-low cholesterol-cancer conundrum. QJM 105:383-388, 2012
3. Nielsen SF, Nordestgaard BG, Bojesen SE: Statin use and reduced cancer-related mortality. N Engl J Med 367:1792-1802, 2012
4. Jackevicius CA, Mamdani M, Tu JV: Adherence with statin therapy in elderly patients with and without acute coronary syndromes. JAMA 288:462-467, 2000
5. Matsuzaki M, Kita T, Mabuchi H, et al: Large scale cohort study of the relationship between serum cholesterol concentration and coronary events with low-dose simvastatin therapy in Japanese patients with hypercholesterolemia. Circ J 66:1087-1095, 2002
6. Rogers HW, Weinstock MA, Harris AR, et al: Incidence estimate of nonmelanoma skin cancer in the United States, 2006. Arch Dermatol 146:283-287, 2010
7. McDougall JA, Malone KE, Daling JR, et al: Long-term statin use and risk of ductal and lobular breast cancer among women 55 to 74 years of age. Cancer Epidemiol Biomarkers Prev 22:1529-1537, 2013
8. Ravnskov U: High cholesterol may protect against infections and atherosclerosis. QJM 96:927-934, 2003
9. Ravnskov U, McCully KM: Vulnerable plaque formation from obstruction of vasa vasorum by homocysteinylated and oxidized lipoprotein aggregates complexed with microbial remnants and LDL autoantibodies. Ann Clin Lab Sci 39:3-16, 2009
10. Antonic V, Stojadinovic A, Kester KE, et al: Significance of infectious agents in colorectal cancer development. J Cancer 4:227-240, 2013