Mutations in the 3c and 7b genes of feline coronavirus in spontaneously affected FIP cats

Research in Veterinary Science

Volumn 97, Issue 2, 2014, Pages 333-340

  Borschensky, C M ^a   Reinacher, M ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

3c gene; 7b gene; Cat; Coronavirus; Mutation

Indexed keywords

3C GENE; 7B GENE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONAVIRUS; FELINE INFECTIOUS PERITONITIS; GENE DELETION; GENE MUTATION; IMMUNOHISTOCHEMISTRY; MUTATIONAL ANALYSIS; NONHUMAN; OPEN READING FRAME; PHYLOGENETIC TREE; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; STOP CODON; VIRUS GENE; AMINO ACID SEQUENCE; ANIMAL; CAT; DNA SEQUENCE; FELINE CORONAVIRUS; GENETICS; MUTATION; RETROSPECTIVE STUDY; VIROLOGY;

CORONAVIRUS; FELIDAE; FELINE CORONAVIRUS; FELINE INFECTIOUS PERITONITIS VIRUS;

STOP CODON; VIRUS DNA;

AMINO ACID SEQUENCE; ANIMALS; CATS; CODON, TERMINATOR; CORONAVIRUS, FELINE; DNA, VIRAL; FELINE INFECTIOUS PERITONITIS; GENE DELETION; MUTATION; RETROSPECTIVE STUDIES; SEQUENCE ANALYSIS, DNA;

EID: 84925182505     PISSN: 00345288     EISSN: 15322661     Source Type: Journal    
DOI: 10.1016/j.rvsc.2014.07.016     Document Type: Article

References (44)

1. Balint, A., Farsang, A., Zadori, Z., Hornyak, A., Dencso, L., Almazan, F., et al., 2012. Molecular characterization of feline infectious peritonitis virus strain DF-2 and studies on the role of ORF3abc in viral cell tropism. Journal of Virology 86, 6258-6267.
2. Battilani, M., Coradin, T., Scagliarini, A., Ciulli, S., Ostanello, F., Prosperi, S., et al., 2003. Quasispecies composition and phylogenetic analysis of feline coronaviruses (FCoVs) in naturally infected cats. FEMS Immunology and Medical Microbiology 39, 141-147.
3. Benetka, V., Kübber-Heiss, A., Kolodziejek, J., Nowotny, N., Hofmann-Parisot, M., Möstl, K., 2004. Prevalence of feline coronavirus types I and II in cats with histopathologically verified feline infectious peritonitis. Veterinary Microbiology 99, 31-42.
4. Brown, M.A., Troyer, J.L., Pecon-Slattery, J., Roelke, M.E., O'Brien, S.J., 2009. Genetics and pathogenesis of feline infectious peritonitis virus. Emerging Infectious Diseases 15, 1445-1452.
5. Chang, H.W., de Groot, R.J., Egberink, H.F., Rottier, P.J., 2010. Feline infectious peritonitis: insights into feline coronavirus pathobiogenesis and epidemiology based on genetic analysis of the viral 3c gene. Journal of General Virology 91, 415-420.
6. Chang, H.W., Egberink, H.F., Halpin, R., Spiro, D.J., Rottier, P.J.M., 2012. Spike protein fusion peptide and feline coronavirus virulence. Emerging Infectious Diseases 18, 1089-1095.
7. De Groot, R.J., Andeweg, A.C., Horzinek, M.C., Spaan,W.J.M., 1988. Sequence analysis of the 3'end of the feline coronavirus FIPV 79-1146 genome: comparison with the genome of porcine coronavirus TGEV reveals large insertions. Virology 167, 370-376.
8. Dedeurwaerder, A., Desmarets, L.M., Olyslaegers, D.A., Vermeulen, B.L., Dewerchin, H.L., Nauwynck, H.J., 2013. The role of accessory proteins in the replication of feline infectious peritonitis virus in peripheral blood monocytes. Veterinary Microbiology 162, 447-455.
9. Dedeurwaerder, A., Olyslaegers, D.A., Desmarets, L.M., Roukaerts, I.D., Theuns, S., Nauwynck, H.J., 2014. ORF 7-encoded accessory protein 7a of feline infectious peritonitis virus as a counteragent against IFN-alpha-induced antiviral response. Journal of General Virology 95, 393-402.
10. Dewerchin, H.L., Cornelissen, E., Nauwynck, H.J., 2005. Replication of feline coronaviruses in peripheral blood monocytes. Archives of Virology 150, 2483-2500.
11. Gunn-Moore, D.A., Gruffydd-Jones, T.J., Harbour, D.A., 1998. Detection of feline coronaviruses by culture and reverse transcriptase-polymerase chain reaction of blood samples from healthy cats and cats with clinical feline infectious peritonitis. Veterinary Microbiology 62, 193-205.
12. Gunn-Moore, D.A., Gunn-Moore, F.J., Gruffyd-Jones, T.J., Harbour, D.A., 1999. Detection of FCoV quasispecies using denaturing gradient gel electrophoresis. Veterinary Microbiology 69, 127-130.
13. Herrewegh, A.A., Mähler, M., Hedrich, H.J., Haagmans, B.L., Egberink, H.F., Horzinek, M.C., et al., 1997. Persistence and evolution of feline coronaviruses in a closed cat-breeding colony. Virology 234, 349-363.
14. Herrewegh, A.A.P.M., de Groot, R.J., Cepica, A., Egberink, H.F., Horzinek, M.C., Rottier, P.J.M., 1995a. Detection of feline coronavirus RNA in feces, tissues, and body fluids of naturally infected cats by reverse transcriptase PCR. Journal of Clinical Microbiology 33, 684-689.
15. Herrewegh, A.A.P.M., Vennema, H., Horzinek, M.C., Rottier, P.J.M., de Groot, R.J., 1995b. The molecular genetics of feline coronaviruses: comparative sequence analysis of the ORF 7a/7b transcription unit of different biotypes. Virology 212, 622-631.
16. Herrewegh, A.A.P.M., Smeenk, I., Horzinek, M.C., Rottier, P.J.M., de Groot, R.J., 1998. Feline coronavirus type II strains 79-1683 and 79-1146 originate from a double recombination between feline coronavirus type I and canine coronavirus. Journal of Virology 72, 4508-4514.
17. Hohdatsu, T., Okada, S., Ishizuka, Y., Yamada, H., Koyama, H., 1992. The prevalence of types I and II feline coronavirus infections in cats. Journal of VeterinaryMedical Science 54, 557-562.
18. Kennedy, M., Boedeker, N., Gibbs, P., Kania, S., 2001. Deletions in the 7a ORF of feline coronavirus associated with an epidemic of feline infectious peritonitis. Veterinary Microbiology 81, 227-234.
19. Kennedy, M., Moore, E., Wilkes, R.P., Citino, S.B., Kania, S.A., 2006. Analysis of genetic mutations in the 7a7b open reading frame of coronavirus of cheetahs (Acinonyx jubatus). American Journal of Veterinary Research 67, 627-632.
20. Kipar, A., Bellmann, S., Gunn-Moore, D.A., Leukert, W., Köhler, K., Menger, S., et al., 1999. Histopathological alterations of lymphatic tissues in cats without feline infectious peritonitis after long-term exposure to FIP virus. Veterinary Microbiology 69, 131-137.
21. Kipar, A., Meli, M.L., Baptiste, K.E., Bowker, L.J., Lutz, H., 2010. Sites of feline coronavirus persistence in healthy cats. Journal of General Virology 91, 1698-1707.
22. Kiss, I., Kecskeméti, S., Tanyi, J., Klingeborn, B., Belák, S., 2000. Preliminary studies on feline coronavirus distribution in naturally and experimentally infected cats. Research in Veterinary Science 68, 237-242.
23. Kummrow, M., Meli, M.L., Haessig, M., Goenczi, E., Poland, A., Pedersen, N.C., et al., 2005. Feline coronavirus serotypes 1 and 2: seroprevalence and association with disease in Switzerland. Clinical and Diagnostic Laboratory Immunology 12, 1209-1215.
24. Lai, M.M.C., Cavanagh, D., 1997. The molecular biology of coronaviruses. Advances in Virus Research 48, 1-100.
25. Lai, M.M.C., Perlman, S., Anderson, L.J., 2007. Coronaviridae. In: Knipe, D.M., Howley, P.M. (Eds.), Fields Virology, vol. 1. Lippincott Williams & Wilkins, Philadelphia, New York, pp. 1305-1333.
26. Lin, C.-N., Su, B.-L.,Wang, C.-H., Hsieh, M.-W., Chueh, T.-J., Chueh, L.-L., 2009a. Genetic diversity and correlation with feline infectious peritonitis of feline coronavirus type I and II: a 5-year study in Taiwan. Veterinary Microbiology 136, 233-239.
27. Lin, C.-N., Su, B.-L., Huang, H.-P., Lee, J.-J., Hsieh, M.-W., Chueh, L.-L., 2009b. Field strain feline coronaviruses with small deletions in ORF7b associated with both enteric infection and feline infectious peritonitis. Journal of Feline Medicine and Surgery 11, 413-419.
28. Masters, P.S., 2006. The molecular biology of coronaviruses. Advances in Virus Research 66, 193-292.
29. Motokawa, K., Hohdatsu, T., Hashimoto, H., Koyama, H., 1996. Comparison of the amino acid sequence and phylogenetic analysis of the peplomer, integral membrane and nucleocapsid proteins of feline, canine and porcine coronaviruses. Microbiology and Immunology 40, 425-433.
30. Pedersen, N.C., Boyle, J.F., Floyd, K., Fudge, A., Barker, J., 1981. An enteric coronavirus infection of cats and its relationship to feline infectious peritonitis. American Journal of Veterinary Research 42, 368-377.
31. Pedersen, N.C., Evermann, J.F., McKeirnan, A.J., Ott, R.L., 1984. Pathogenicity studies of feline coronavirus isolates 79-1146 and 79-1683. American Journal of Veterinary Research 45, 2580-2585.
32. Pedersen, N.C., Liu, H., Dodd, K.A., Pesavento, P.A., 2009. Significance of coronavirus mutants in feces and diseased tissues of cats suffering from feline infectious peritonitis. Viruses 1, 166-184.
33. Pedersen, N.C., Liu, H., Scarlett, J., Leutenegger, C.M., Golovko, L., Kennedy, H., et al., 2012. Feline infectious peritonitis: role of the feline coronavirus 3c gene in intestinal tropism and pathogenicity based upon isolates from resident and adopted shelter cats. Virus Research 165, 17-28.
34. Poland, A.M., Vennema, H., Foley, J.E., Pedersen, N.C., 1996. Two related strains of feline infectious peritonitis virus isolated from immunocompromised cats infected with a feline enteric coronavirus. Journal of Clinical Microbiology 34, 3180-3184.
35. Porter, E., Tasker, S., Day, M.J., Harley, R., Kipar, A., Siddell, S.G., et al., 2014. Amino acid changes in the spike protein of feline coronavirus correlate with systemic spread of virus from the intestine and not with feline infectious peritonitis. Veterinary Research 45, 49. doi:10.1186/1297-9716-45-49.
36. Rottier, P.J.M., Nakamura, K., Schellen, P., Volders, H., Haijema, B.J., 2005. Acquisition of macrophage tropism during the pathogenesis of feline infectious peritonitis is determined by mutations in the feline coronavirus spike protein. Journal of Virology 79, 14122-14130.
37. Stoddart, C.A., Scott, F.W., 1989. Intrinsic resistance of feline peritoneal macrophages to coronavirus infection correlates with in vivo virulence. Journal of Virology 63, 436-440.
38. Stoddart, M.E., Gaskell, R.M., Harbour, D.A., Pearson, G.R., 1988. The sites of early viral replication in feline infectious peritonitis. Veterinary Microbiology 18, 259-271.
39. Tekes, G., Hofmann-Lehmann, R., Stallkamp, I., Thiel, V., Thiel, H.-J., 2008. Genome organization and reverse genetic analysis of a type I feline coronavirus. Journal of Virology 82, 1851-1859.
40. Tekes, G., Spies, D., Bank-Wolf, B., Thiel, V., Thiel, H.J., 2012. A reverse genetic approach to study feline infectious peritonitis. Journal of Virology 86, 6994-6998.
41. Vennema, H., 1999. Genetic drift and genetic shift during feline coronavirus evolution. Veterinary Microbiology 69, 139-141.
42. Vennema, H., Heijnen, L., Rottier, P.J.M., Horzinek, M.C., Spaan, W.J.M., 1992a. A novel glycoprotein of feline infectious peritonitis coronavirus contains a KDEL-like endoplasmic reticulum retention signal. Journal of Virology 66, 4951-4956.
43. Vennema, H., Rossen, J.W.A., Wesseling, J., Horzinek, M.C., Rottier, P.J.M., 1992b. Genomic organization and expression of the 3'end of the canine and feline enteric coronaviruses. Virology 191, 134-140.
44. Vennema, H., Poland, A., Foley, J., Pedersen, N.C., 1998. Feline infectious peritonitis viruses arise by mutation from endemic feline enteric coronaviruses. Virology 243, 150-157.