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Volumn 51, Issue 4, 2015, Pages 473-481

Capecitabine, oxaliplatin and irinotecan in combination, with bevacizumab (COI-B regimen) as first-line treatment of patients with advanced colorectal cancer. An Italian Trials of Medical Oncology phase II study

Author keywords

Bevacizumab; Capecitabine; Colorectal cancer; Triplet chemotherapy

Indexed keywords

BEVACIZUMAB; CAPECITABINE; IRINOTECAN; OXALIPLATIN; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; DEOXYCYTIDINE; FLUOROURACIL; MONOCLONAL ANTIBODY; PLATINUM COMPLEX;

EID: 84925012061     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2014.12.020     Document Type: Article
Times cited : (15)

References (30)
  • 2
    • 0014439920 scopus 로고
    • The natural history of primary and secondary malignant tumors of the liver. I. The prognosis for patients with hepatic metastases from colonic and rectal carcinoma by laparotomy
    • S. Bengmark, and L. Hafstrom The natural history of primary and secondary malignant tumors of the liver. I. The prognosis for patients with hepatic metastases from colonic and rectal carcinoma by laparotomy Cancer 23 1969 198 202
    • (1969) Cancer , vol.23 , pp. 198-202
    • Bengmark, S.1    Hafstrom, L.2
  • 3
    • 2142703727 scopus 로고    scopus 로고
    • Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment
    • A. Grothey, D. Sargent, and R.M. Goldberg Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment J Clin Oncol 22 2004 1209 1214
    • (2004) J Clin Oncol , vol.22 , pp. 1209-1214
    • Grothey, A.1    Sargent, D.2    Goldberg, R.M.3
  • 4
    • 1342290189 scopus 로고    scopus 로고
    • FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study
    • C. Tournigand, T. André, and E. Achille FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study J Clin Oncol 22 2004 229 237
    • (2004) J Clin Oncol , vol.22 , pp. 229-237
    • Tournigand, C.1    André, T.2    Achille, E.3
  • 5
    • 84872369732 scopus 로고    scopus 로고
    • Second-line therapy for advanced colorectal cancer
    • A.P. Guglielmi, and A.F. Sobrero Second-line therapy for advanced colorectal cancer Gastrointest Cancer Res 1 2007 57 63
    • (2007) Gastrointest Cancer Res , vol.1 , pp. 57-63
    • Guglielmi, A.P.1    Sobrero, A.F.2
  • 6
    • 34249000361 scopus 로고    scopus 로고
    • Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: The Gruppo Oncologico Nord Ovest
    • A. Falcone, S. Ricci, and I. Brunetti Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: the Gruppo Oncologico Nord Ovest J Clin Oncol 25 2007 1670 1676
    • (2007) J Clin Oncol , vol.25 , pp. 1670-1676
    • Falcone, A.1    Ricci, S.2    Brunetti, I.3
  • 7
    • 33645309877 scopus 로고    scopus 로고
    • FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): A multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG)
    • J. Souglakos, N. Androulakis, and K. Syrigos FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): a multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG) Br J Cancer 94 2006 798 805
    • (2006) Br J Cancer , vol.94 , pp. 798-805
    • Souglakos, J.1    Androulakis, N.2    Syrigos, K.3
  • 8
    • 38449107093 scopus 로고    scopus 로고
    • Capecitabine plus oxaliplatin and irinotecan regimen every other week: A phase I/II study in first-line treatment of metastatic colorectal cancer
    • E. Bajetta, L. Celio, and E. Ferrario Capecitabine plus oxaliplatin and irinotecan regimen every other week: a phase I/II study in first-line treatment of metastatic colorectal cancer Ann Oncol 18 2007 1810 1816
    • (2007) Ann Oncol , vol.18 , pp. 1810-1816
    • Bajetta, E.1    Celio, L.2    Ferrario, E.3
  • 9
    • 84925009643 scopus 로고    scopus 로고
    • Bevacizumab summary of product characteristics. (last entry 09.04.14)
    • Bevacizumab summary of product characteristics. Available at: < http://www.accessdata.fda.gov/drugsatfda-docs/label/2009/125085s0169lbl.pdf > (last entry 09.04.14).
  • 10
    • 77956189945 scopus 로고    scopus 로고
    • Bevacizumab with FOLFOXIRI (irinotecan, oxaliplatin, fluorouracil, and folinate) as first-line treatment for metastatic colorectal cancer: A phase 2 trial
    • G. Masi, F. Loupakis, and L. Salvatore Bevacizumab with FOLFOXIRI (irinotecan, oxaliplatin, fluorouracil, and folinate) as first-line treatment for metastatic colorectal cancer: a phase 2 trial Lancet Oncol 11 2010 845 852
    • (2010) Lancet Oncol , vol.11 , pp. 845-852
    • Masi, G.1    Loupakis, F.2    Salvatore, L.3
  • 11
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • P. Therasse, S.G. Arbuck, and E.A. Eisenhauer New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada J Natl Cancer Inst 92 2000 205 216
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3
  • 12
    • 84902544715 scopus 로고    scopus 로고
    • Lack of KRAS, NRAS, BRAF and TP53 mutations improves outcome of elderly metastatic colorectal cancer patients treated with cetuximab, oxaliplatin and UFT
    • on behalf of Italian Trials in Medical Oncology (ITMO) Group
    • M. Di Bartolomeo, F. Pietrantonio, F. Perrone on behalf of Italian Trials in Medical Oncology (ITMO) Group Lack of KRAS, NRAS, BRAF and TP53 mutations improves outcome of elderly metastatic colorectal cancer patients treated with cetuximab, oxaliplatin and UFT Target Oncol 9 2014 155 162
    • (2014) Target Oncol , vol.9 , pp. 155-162
    • Di Bartolomeo, M.1    Pietrantonio, F.2    Perrone, F.3
  • 13
    • 79960435101 scopus 로고    scopus 로고
    • Increased detection sensitivity for KRAS mutations enhances the prediction of anti-EGFR monoclonal antibody resistance in metastatic colorectal cancer
    • F. Molinari, L. Felicioni, and M. Buscarino Increased detection sensitivity for KRAS mutations enhances the prediction of anti-EGFR monoclonal antibody resistance in metastatic colorectal cancer Clin Cancer Res 17 2011 4901 4914
    • (2011) Clin Cancer Res , vol.17 , pp. 4901-4914
    • Molinari, F.1    Felicioni, L.2    Buscarino, M.3
  • 15
    • 0024536437 scopus 로고
    • Optimal two-stage design for phase II clinical trials
    • R. Simon Optimal two-stage design for Phase II clinical trials Control Clin Trials 10 1989 1 10
    • (1989) Control Clin Trials , vol.10 , pp. 1-10
    • Simon, R.1
  • 16
    • 33847333193 scopus 로고    scopus 로고
    • Importance of histological tumor response assessment in predicting the outcome in patients with colorectal liver metastases treated with neo-adjuvant chemotherapy followed by liver surgery
    • L. Rubbia-Brandt, E. Giostra, and C. Brezault Importance of histological tumor response assessment in predicting the outcome in patients with colorectal liver metastases treated with neo-adjuvant chemotherapy followed by liver surgery Ann Oncol 18 2007 299 304
    • (2007) Ann Oncol , vol.18 , pp. 299-304
    • Rubbia-Brandt, L.1    Giostra, E.2    Brezault, C.3
  • 17
    • 84918818370 scopus 로고    scopus 로고
    • Incidence and relative risk of grade 3 and 4 diarrhea in patients treated with capecitabine or 5-fluorouracil. A meta-analysis of published trials
    • [Epub ahead of print]
    • R. Iacovelli, F. Pietrantonio, and A. Palazzo Incidence and relative risk of grade 3 and 4 diarrhea in patients treated with capecitabine or 5-fluorouracil. A meta-analysis of published trials Br J Clin Pharmacol 24 2014 [Epub ahead of print]
    • (2014) Br J Clin Pharmacol , vol.24
    • Iacovelli, R.1    Pietrantonio, F.2    Palazzo, A.3
  • 18
    • 77955229256 scopus 로고    scopus 로고
    • Review of benefits and risks of second-line irinotecan monotherapy for advanced colorectal cancer
    • L.J. Oostendorp, P.F. Stalmeier, and P.C. Pasker-de Jong Review of benefits and risks of second-line irinotecan monotherapy for advanced colorectal cancer Anticancer Drugs 21 2010 749 758
    • (2010) Anticancer Drugs , vol.21 , pp. 749-758
    • Oostendorp, L.J.1    Stalmeier, P.F.2    Pasker-De Jong, P.C.3
  • 19
    • 43049126513 scopus 로고    scopus 로고
    • Irinotecan combined with infusional 5-fluorouracil/folinic acid or capecitabine plus celecoxib or placebo in the first-line treatment of patients with metastatic colorectal cancer. EORTC study 40015
    • C.H. Köhne, J. De Greve, and J.T. Hartmann Irinotecan combined with infusional 5-fluorouracil/folinic acid or capecitabine plus celecoxib or placebo in the first-line treatment of patients with metastatic colorectal cancer. EORTC study 40015 Ann Oncol 19 2008 920 926
    • (2008) Ann Oncol , vol.19 , pp. 920-926
    • Köhne, C.H.1    De Greve, J.2    Hartmann, J.T.3
  • 20
    • 36048960109 scopus 로고    scopus 로고
    • Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: Results from the BICC-C study
    • C.S. Fuchs, J. Marshall, and E. Mitchell Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: results from the BICC-C study J Clin Oncol 25 2007 4779 4786
    • (2007) J Clin Oncol , vol.25 , pp. 4779-4786
    • Fuchs, C.S.1    Marshall, J.2    Mitchell, E.3
  • 21
    • 77954346705 scopus 로고    scopus 로고
    • Advanced colorectal cancer: ESMO clinical practice guidelines for treatment
    • ESMO Guidelines Working Group
    • E. Van Cutsem, B. Nordlinger, A. Cervantes ESMO Guidelines Working Group Advanced colorectal cancer: ESMO clinical practice guidelines for treatment Ann Oncol 21 suppl. 5 2010 93 97
    • (2010) Ann Oncol , vol.21 , pp. 93-97
    • Van Cutsem, E.1    Nordlinger, B.2    Cervantes, A.3
  • 22
    • 84925009642 scopus 로고    scopus 로고
    • Prospective observational study for DPYD and UGT1A1 deficiency-associated toxicity in patients with metastatic colorectal cancer (mCRC) receiving triplet chemotherapy with capecitabine, irinotecan and oxaliplatin (COI)
    • [Abstr 532P]
    • F.S. Falvella, S. Cheli, and C. Maggi Prospective observational study for DPYD and UGT1A1 deficiency-associated toxicity in patients with metastatic colorectal cancer (mCRC) receiving triplet chemotherapy with capecitabine, irinotecan and oxaliplatin (COI) Ann Oncol 25 suppl. 4 2014 [Abstr 532P]
    • (2014) Ann Oncol , vol.25
    • Falvella, F.S.1    Cheli, S.2    Maggi, C.3
  • 23
    • 0035099803 scopus 로고    scopus 로고
    • Ternary combination of irinotecan, fluorouracil-folinic acid and oxaliplatin: Results on human colon cancer cell lines
    • J.L. Fischel, P. Rostagno, and P. Formento Ternary combination of irinotecan, fluorouracil-folinic acid and oxaliplatin: results on human colon cancer cell lines Br J Cancer 84 2001 579 585
    • (2001) Br J Cancer , vol.84 , pp. 579-585
    • Fischel, J.L.1    Rostagno, P.2    Formento, P.3
  • 24
    • 84894598632 scopus 로고    scopus 로고
    • Randomized, phase II study of bevacizumab with mFOLFOX6 or FOLFOXIRI in patients with initially unresectable liver metastases from colorectal cancer: Resectability and safety in OLIVIA
    • [abstr 3619]
    • T. Gruenberger, J.A. Bridgewater, and I. Chau Randomized, phase II study of bevacizumab with mFOLFOX6 or FOLFOXIRI in patients with initially unresectable liver metastases from colorectal cancer: resectability and safety in OLIVIA J Clin Oncol 24 suppl. 2013 [abstr 3619]
    • (2013) J Clin Oncol , vol.24
    • Gruenberger, T.1    Bridgewater, J.A.2    Chau, I.3
  • 25
    • 84891629487 scopus 로고    scopus 로고
    • FOLFOXIRI plus bevacizumab as first-line treatment in BRAF mutant metastatic colorectal cancer
    • F. Loupakis, C. Cremolini, and L. Salvatore FOLFOXIRI plus bevacizumab as first-line treatment in BRAF mutant metastatic colorectal cancer Eur J Cancer 50 1 2014 57 63
    • (2014) Eur J Cancer , vol.50 , Issue.1 , pp. 57-63
    • Loupakis, F.1    Cremolini, C.2    Salvatore, L.3
  • 26
    • 84908139591 scopus 로고    scopus 로고
    • Initial therapy with FOLFOXIRI and bevacizumab for metastatic colorectal cancer
    • F. Loupakis, C. Cremolini, and G. Masi Initial therapy with FOLFOXIRI and bevacizumab for metastatic colorectal cancer N Engl J Med 371 2014 1609 1618
    • (2014) N Engl J Med , vol.371 , pp. 1609-1618
    • Loupakis, F.1    Cremolini, C.2    Masi, G.3
  • 27
    • 84892367773 scopus 로고    scopus 로고
    • Bevacizumab continuation versus no continuation after first-line chemo-bevacizumab therapy in patients with metastatic colorectal cancer: A randomized phase III noninferiority trial (SAKK 41/06)
    • [abstr 3503]
    • D. Koeberle, D.C. Betticher, and R. Von Moos Bevacizumab continuation versus no continuation after first-line chemo-bevacizumab therapy in patients with metastatic colorectal cancer: a randomized phase III noninferiority trial (SAKK 41/06) J Clin Oncol 31 suppl. 2013 [abstr 3503]
    • (2013) J Clin Oncol , vol.31
    • Koeberle, D.1    Betticher, D.C.2    Von Moos, R.3
  • 28
    • 84911463475 scopus 로고    scopus 로고
    • Final results and subgroup analyses of the phase 3 CAIRO3 study: Maintenance treatment with capecitabine + bevacizumab versus observation after induction treatment with chemotherapy + bevacizumab in metastatic colorectal cancer (mCRC)
    • [abstr 3504]
    • M. Koopman, L.H. Simkens, and A.M. May Final results and subgroup analyses of the phase 3 CAIRO3 study: maintenance treatment with capecitabine + bevacizumab versus observation after induction treatment with chemotherapy + bevacizumab in metastatic colorectal cancer (mCRC) J Clin Oncol 32 suppl. 5 2014 [abstr 3504]
    • (2014) J Clin Oncol , vol.32
    • Koopman, M.1    Simkens, L.H.2    May, A.M.3
  • 29
    • 84907027295 scopus 로고    scopus 로고
    • Maintenance strategy with fluoropyrimidines (FP) plus bevacizumab (Bev), Bev alone, or no treatment, following a standard combination of FP, oxaliplatin (Ox), and Bev as first-line treatment for patients with metastatic colorectal cancer (mCRC): A phase III non-inferiority trial (AIO KRK 0207)
    • [abstr 3503]
    • D. Arnold, U. Graeven, and C.A. Lerchenmuller Maintenance strategy with fluoropyrimidines (FP) plus bevacizumab (Bev), Bev alone, or no treatment, following a standard combination of FP, oxaliplatin (Ox), and Bev as first-line treatment for patients with metastatic colorectal cancer (mCRC): a phase III non-inferiority trial (AIO KRK 0207) J Clin Oncol 32 suppl. 5 2014 [abstr 3503]
    • (2014) J Clin Oncol , vol.32
    • Arnold, D.1    Graeven, U.2    Lerchenmuller, C.A.3
  • 30
    • 84869406393 scopus 로고    scopus 로고
    • Continuing single-agent bevacizumab as maintenance therapy after induction XELOX(or FOLFOX) plus bevacizumab in first-line treatment of metastatic colorectal cancer
    • E. Díaz-Rubio, F. Pietrantonio, and F. de Braud Continuing single-agent bevacizumab as maintenance therapy after induction XELOX(or FOLFOX) plus bevacizumab in first-line treatment of metastatic colorectal cancer Oncologist 17 2012 1426 1428
    • (2012) Oncologist , vol.17 , pp. 1426-1428
    • Díaz-Rubio, E.1    Pietrantonio, F.2    De Braud, F.3


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