The Choice of normative pediatric reference database changes spine bone mineral density Z-scores but not the relationship between bone mineral density and prevalent vertebral fractures

Journal of Clinical Endocrinology and Metabolism

Volumn 100, Issue 3, 2015, Pages 1018-1027

  Ma, Jinhui ^a   Siminoski, Kerry ^b   Alos, Nathalie ^c   Halton, Jacqueline ^d   Ho, Josephine ^e   Lentle, Brian ^f   Matzinger, MaryAnn ^d   Shenouda, Nazih ^d   Atkinson, Stephanie ^g   Barr, Ronald ^g   Cabral, David A ^f   Couch, Robert ^b   Cummings, Elizabeth A ^h   Fernandez, Conrad V ^h   Grant, Ronald M ⁱ   Rodd, Celia ^j   Sbrocchi, Anne Marie ^k   Scharke, Maya ^a   Rauch, Frank ^k   Ward, Leanne M ^d  

^a CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d UNIVERSITY OF OTTAWA   (Canada)

^e UNIVERSITY OF CALGARY   (Canada)

^f UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^g MCMASTER UNIVERSITY   (Canada)

^h DALHOUSIE UNIVERSITY   (Canada)

ⁱ UNIVERSITY OF TORONTO   (Canada)

^j UNIVERSITY OF MANITOBA   (Canada)

^k MCGILL UNIVERSITY   (Canada)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; AGE DISTRIBUTION; AREA UNDER THE CURVE; ARTICLE; BONE DENSITY; BONE FRAGILITY; CALIBRATION; CHILD; CHILDHOOD LEUKEMIA; COHORT ANALYSIS; CONTROLLED STUDY; DATA ANALYSIS SOFTWARE; DISEASE ASSOCIATION; DISEASE SEVERITY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; HUMAN; LUMBAR SPINE BONE MINERAL DENSITY Z SCORE; MAJOR CLINICAL STUDY; MALE; MUSCULOSKELETAL SYSTEM PARAMETERS; NEWBORN; PREDICTIVE VALUE; PRESCHOOL CHILD; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; REFERENCE DATABASE; SCHOOL CHILD; SCORING SYSTEM; SPINE FRACTURE; SPINE RADIOGRAPHY; VALIDITY; DECISION MAKING; FACTUAL DATABASE; INFANT; INJURIES; LUMBAR VERTEBRA; METHODOLOGY; PHOTON ABSORPTIOMETRY; PREVALENCE; RADIOGRAPHY; REFERENCE VALUE; SPINAL FRACTURES; STANDARDS;

ABSORPTIOMETRY, PHOTON; ADOLESCENT; BONE DENSITY; CHILD; CHILD, PRESCHOOL; CHOICE BEHAVIOR; DATABASES, FACTUAL; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; LUMBAR VERTEBRAE; MALE; PREVALENCE; REFERENCE VALUES; RESEARCH DESIGN; ROC CURVE; SPINAL FRACTURES;

EID: 84924957017     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2014-3096     Document Type: Article

References (34)

1. Kilpinen-Loisa P, Paasio T, Soiva M, et al. Lowbone mass in patients with motor disability: prevalence and risk factors in 59 Finnish children. Dev Med Child Neurol. 2010;52:276-282.
2. King WM, Ruttencutter R, Nagaraja HN, et al. Orthopedic outcomes of long-term daily corticosteroid treatment in Duchenne muscular dystrophy. Neurology. 2007;68:1607-1613.
3. Högler W, Wehl G, van Staa T, Meister B, Klein-Franke A, Kropshofer G. Incidence of skeletal complications during treatment of childhood acute lymphoblastic leukemia: comparison of fracture risk with the General Practice Research Database. Pediatr Blood Cancer. 2007;48:21-27.
4. Burnham JM, Shults J, Weinstein R, Lewis JD, Leonard MB. Childhood onset arthritis is associated with an increased risk of fracture: a population based study using the General Practice Research Database. Ann Rheum Dis. 2006;65:1074-1079.
5. Rodd C, Lang B, Ramsay T, et al. Incident vertebral fractures among children with rheumatic disorders 12 months after glucocorticoid initiation: a national observational study. Arthritis Care Res (Hoboken). 2012;64:122-131.
6. Halton J, Gaboury I, Grant R, et al. Advanced vertebral fracture among newly diagnosed children with acute lymphoblastic leukemia: results of the Canadian Steroid-Associated Osteoporosis in the Pediatric Population (STOPP) research program. J Bone Miner Res. 2009;24:1326-1334.
7. Alos N, Grant RM, Ramsay T, et al. High incidence of vertebral fractures in children with acute lymphoblastic leukemia 12 months after the initiation of therapy. J Clin Oncol. 2012;30:2760-2767.
8. Ben Amor IM, Roughley P, Glorieux FH, Rauch F. Skeletal clinical characteristics of osteogenesis imperfecta caused by haploinsufficiency mutations in COL1A1. J Bone Miner Res. 2013;28:2001-2007.
9. Henderson RC, Berglund LM, May R, et al. The relationship between fractures and DXA measures of BMD in the distal femur of children and adolescents with cerebral palsy or muscular dystrophy. J Bone Miner Res. 2010;25:520-526.
10. Leonard MB, Propert KJ, Zemel BS, Stallings VA, Feldman HI. Discrepancies in pediatric bone mineral density reference data: potential for misdiagnosis of osteopenia. J Pediatr. 1999;135:182-188.
11. Kocks J, Ward K, Mughal Z, Moncayo R, Adams J, Högler W. Z-score comparability of bone mineral density reference databases for children. J Clin Endocrinol Metab. 2010;95:4652-4659.
12. Bishop N, Arundel P, Clark E, et al. Fracture prediction and the definition of osteoporosis in children and adolescents: the ISCD 2013 pediatric official positions. J Clin Densitom. 2014;17:275-280.
13. Siminoski K, Lee KC, Jen H, et al. Anatomical distribution of vertebral fractures: comparison of pediatric and adult spines. Osteoporos Int. 2012;23:1999-2008.
14. Genant HK, Wu CY, van Kuijk C, Nevitt MC. Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res. 1993;8:1137-1148.
15. Hologic Inc: Hologic Apex 3.1 Normative Database. Summary of Hologic Reference Data - Apex 3.1. Bedford, MA: Hologic, Inc; 2010.
16. Zemel BS, Kalkwarf HJ, Gilsanz V, et al. Revised reference curves for bone mineral content and areal bone mineral density according to age and sex for black and non-black children: results of the bone mineral density in childhood study. J Clin Endocrinol Metab. 2011;96:3160-3169.
17. Zemel BS, Kalkwarf HJ, Gilsanz V, et al. Revised reference curves for bone mineral content and areal bone mineral density according to age and sex for black and non-black children: results of the bone mineral density in childhood study [published erratum appears in Erratum in: J Clin Endocrinol Metab. 2013;98:420]. J Clin Endocrinol Metab. 2011;96:96:3160-3169.
18. Cochran WG. The combination of estimates from different experiments. Biometrics. 1954;10:110-129.
19. Leening MJ, Vedder MM, Witteman JC, Pencina MJ, Steyerberg EW. Net reclassification improvement: computation, interpretation, and controversies: a literature review and clinician's guide. Ann Intern Med. 2014;160:122-131.
20. Bonnick SL. Hologic 12.3. In: Bonnick SL, ed. Bone Densitometry in Clinical Practice: Application and Interpretation. 2nd ed. Totowa, NJ: Humana; 2004:483-492.
21. Kalkwarf HJ, Zemel BS, Yolton K, Heubi JE. Bone mineral content and density of the lumbar spine of infants and toddlers: influence of age, sex, race, growth, and human milk feeding. J Bone Miner Res. 2013;28:206-212.
22. Bachrach LK, Hastie T, Wang MC, Narasimhan B, Marcus R. Bone mineral acquisition in healthy Asian, Hispanic, black, and Caucasian youth: a longitudinal study. J Clin Endocrinol Metab. 1999;84:4702-4712.
23. Webber CE, Beaumont LF, Morrison J, Sala A, Barr RD. Age-predicted values for lumbar spine, proximal femur, and whole-body bone mineral density: results from a population of normal children aged 3 to 18 years. Can Assoc Radiol J. 2007;58:37-45.
24. del Rio L, Carrascosa A, Pons F, Gusinyé M, Yeste D, Domenech FM. Bone mineral density of the lumbar spine in white Mediterranean Spanish children and adolescents: changes related to age, sex, and puberty. Pediatr Res. 1994;35:362-366.
25. van der Sluis IM, de Ridder MA, Boot AM, Krenning EP, de Muinck Keizer-Schrama SM. Reference data for bone density and body composition measured with dual energy x ray absorptiometry in white children and young adults. Arch Dis Child. 2002;87:341-347; discussion 341-347.
26. Pludowski P, Matusik H, Olszaniecka M, Lebiedowski M, Lorenc RS. Reference values for the indicators of skeletal and muscular status of healthy Polish children. J Clin Densitom. 2005;8:164-177.
27. Lunar enCORE pediatric reference data supplement; revision 1 Nov-2010 LU44662. Madison, WI: Lunar GE Healthcare; 2010.
28. Faulkner RA, Bailey DA, Drinkwater DT, McKay HA, Arnold C, Wilkinson AA. Bone densitometry in Canadian children 8-17 years of Age. Calcif Tissue Int. 1996;59:344-351.
29. Rauch F, Plotkin H, DiMeglio L, et al. Fracture prediction and the definition of osteoporosis in children and adolescents: the ISCD 2007 Pediatric Official Positions. J Clin Densitom. 2008;11:22-28.
30. Kanis JA, Oden A, Johansson H, Borgström F, Ström O, McCloskey E. FRAX and its applications to clinical practice. Bone. 2009;44:734-743.
31. Faulkner KG, Glüer CC, Estilo M, Genant HK. Cross-calibration of DXA equipment: upgrading from a Hologic QDR 1000/W to a QDR 2000. Calcif Tissue Int. 1993;52:79-84.
32. Fonseca AS, Szejnfeld VL, Terreri MT, Goldenberg J, Ferraz MB, Hilário MO. Bone mineral density of the lumbar spine of Brazilian children and adolescents aged 6 to 14 years. Braz J Med Biol Res. 2001;34:347-352.
33. Kalkwarf HJ, Zemel BS, Gilsanz V, et al. The bone mineral density in childhood study: bone mineral content and density according to age, sex, and race. J Clin Endocrinol Metab. 2007;92:2087-2099.
34. Kelly TL, Specker BL, Binkely T, et al. Pediatric BMD reference database for US white children. Bone. 2005;36:S102.