Ethical concerns about adaptive randomization

Clinical Trials

Volumn 12, Issue 2, 2015, Pages 101-

  Begg, Colin B ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL RESEARCH; CLINICAL TRIAL (TOPIC); EDITORIAL; EQUIPOISE; ETHICS; HUMAN; PRIORITY JOURNAL; RANDOMIZATION; TREATMENT RESPONSE; METHODOLOGY; RANDOMIZED CONTROLLED TRIAL (TOPIC);

HUMANS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RESEARCH DESIGN;

EID: 84924858791     PISSN: 17407745     EISSN: 17407753     Source Type: Journal    
DOI: 10.1177/1740774515569613     Document Type: Editorial

References (4)

1. Gelber RD, Gelber S. Marvin Zelen, 1927-2014. Clin Trials.:
2. Zelen M. Play the winner rule and the controlled clinical trial. J Am Stat Assoc. 1969 ; 64: 131-146
3. Begg CB. On inferences from Wei's biased coin design for clinical trials (with discussion). Biometrika. 1990 ; 77: 467-484
4. Freedman B. Equipoise and the ethics of clinical research. N Engl J Med. 1987 ; 317: 141-145