Modulation of a pore in the capsid of jc polyomavirus reduces infectivity and prevents exposure of the minor capsid proteins

Journal of Virology

Volumn 89, Issue 7, 2015, Pages 3910-3921

  Nelson, Christian D S ^a   Ströh, Luisa J ^b   Gee, Gretchen V ^a   O'Hara, Bethany A ^a   Stehle, Thilo ^b,c   Atwood, Walter J ^a  

^a BROWN UNIVERSITY   (United States)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN VP1; PROTEIN VP2; CAPSID PROTEIN; MACROMOLECULE; MUTANT PROTEIN; VP1 PROTEIN, POLYOMAVIRUS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; HYDROPHOBICITY; JC VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STABILITY; VIRUS ASSEMBLY; VIRUS CAPSID; VIRUS ENTRY; VIRUS INFECTIVITY; VIRUS REPLICATION; CHEMISTRY; GENETICS; GROWTH, DEVELOPMENT AND AGING; MACROMOLECULE; METABOLISM; PHYSIOLOGY; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); JC POLYOMAVIRUS; MIRIDAE; POLYOMAVIRUS;

AMINO ACID SUBSTITUTION; CAPSID; CAPSID PROTEINS; CRYSTALLOGRAPHY, X-RAY; HUMANS; JC VIRUS; MACROMOLECULAR SUBSTANCES; MUTANT PROTEINS; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; VIRUS ASSEMBLY; VIRUS INTERNALIZATION;

EID: 84924787742     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00089-15     Document Type: Article

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