-
1
-
-
55549147508
-
Dabigatran etexilate: an oral direct thrombin inhibitor for prophylaxis and treatment of thromboembolic diseases
-
Baetz BE, Spinler SA. Dabigatran etexilate: an oral direct thrombin inhibitor for prophylaxis and treatment of thromboembolic diseases. Pharmacotherapy 2001;28:1354-73.
-
(2001)
Pharmacotherapy
, vol.28
, pp. 1354-1373
-
-
Baetz, B.E.1
Spinler, S.A.2
-
2
-
-
77949421739
-
Influence of renal impairment on the pharmacokinetics and pharmacodynamics of oral dabigatran etexilate: an open-label, parallel-group, single-centre study
-
Stangier J, Rathgen K, Stahle H, Mazur D. Influence of renal impairment on the pharmacokinetics and pharmacodynamics of oral dabigatran etexilate: an open-label, parallel-group, single-centre study. Clin Pharmacokinet 2010;49:259-68.
-
(2010)
Clin Pharmacokinet
, vol.49
, pp. 259-268
-
-
Stangier, J.1
Rathgen, K.2
Stahle, H.3
Mazur, D.4
-
3
-
-
84857853180
-
Bleeding risk with dabigatran in the frail elderly
-
Harper P, Young L, Merriman E. Bleeding risk with dabigatran in the frail elderly. N Engl J Med 2012;366:864-6.
-
(2012)
N Engl J Med
, vol.366
, pp. 864-866
-
-
Harper, P.1
Young, L.2
Merriman, E.3
-
4
-
-
79960955075
-
The use of dabigatran in elderly patients
-
Legrand M, Mateo J, Aribaud A, Ginisty S, Eftekhari P, Huy PT, Drouet L, Payen D. The use of dabigatran in elderly patients. Arch Intern Med 2011;171:1285-6.
-
(2011)
Arch Intern Med
, vol.171
, pp. 1285-1286
-
-
Legrand, M.1
Mateo, J.2
Aribaud, A.3
Ginisty, S.4
Eftekhari, P.5
Huy, P.T.6
Drouet, L.7
Payen, D.8
-
5
-
-
84863660210
-
Dabigatran: uncharted waters and potential harms
-
Radecki RP. Dabigatran: uncharted waters and potential harms. Ann Intern Med 2012;157:66-8.
-
(2012)
Ann Intern Med
, vol.157
, pp. 66-68
-
-
Radecki, R.P.1
-
6
-
-
84859788384
-
Dabigatran etexilate for stroke prevention in patients with atrial fibrillation: resolving uncertainties in routine practice
-
Huisman MV, Lip GY, Diener HC, Brueckmann M, van Ryn J, Clemens A. Dabigatran etexilate for stroke prevention in patients with atrial fibrillation: resolving uncertainties in routine practice. Thromb Haemost 2012;107:838-47.
-
(2012)
Thromb Haemost
, vol.107
, pp. 838-847
-
-
Huisman, M.V.1
Lip, G.Y.2
Diener, H.C.3
Brueckmann, M.4
van Ryn, J.5
Clemens, A.6
-
7
-
-
4644224760
-
-
eMC. (Last update on eMC:30/04/2012).
-
eMC. Summary of Product Characteristics: Prada. 2012 (Last update on eMC:30/04/2012); http://www.medicines.org.uk/emc/medicine/24839/SPC.
-
(2012)
Summary of Product Characteristics: Prada
-
-
-
8
-
-
85011116329
-
A detailed comparison of the performance of the standard versus the Nijmegen modification of the Bethesda assay in detecting factor VIII: C inhibitors in the haemophilia A population of Canada. Association of Hemophilia Centre Directors of Canada. Factor VIII/IX Subcommittee of Scientific and Standardization Committee of International Society on Thrombosis and Haemostasis
-
Giles AR, Verbruggen B, Rivard GE, Teitel J, Walker I. A detailed comparison of the performance of the standard versus the Nijmegen modification of the Bethesda assay in detecting factor VIII: C inhibitors in the haemophilia A population of Canada. Association of Hemophilia Centre Directors of Canada. Factor VIII/IX Subcommittee of Scientific and Standardization Committee of International Society on Thrombosis and Haemostasis. Thromb Haemost 1992;79:872-5.
-
(1992)
Thromb Haemost
, vol.79
, pp. 872-875
-
-
Giles, A.R.1
Verbruggen, B.2
Rivard, G.E.3
Teitel, J.4
Walker, I.5
-
9
-
-
84878661546
-
-
Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.
-
Product information. Pradaxa (Dabigatran Etexilate Mesylate). Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2012.
-
(2012)
Pradaxa (Dabigatran Etexilate Mesylate)
-
-
-
10
-
-
41949116970
-
Clinical pharmacokinetics and pharmacodynamics of the oral direct thrombin inhibitor dabigatran etexilate
-
Stangier J. Clinical pharmacokinetics and pharmacodynamics of the oral direct thrombin inhibitor dabigatran etexilate. Clin Pharmacokinet 2008;47:285-95.
-
(2008)
Clin Pharmacokinet
, vol.47
, pp. 285-295
-
-
Stangier, J.1
-
11
-
-
77952167209
-
Pharmacology, pharmacokinetics, and pharmacodynamics of dabigatran etexilate, an oral direct thrombin inhibitor
-
Stangier J, Clemens A. Pharmacology, pharmacokinetics, and pharmacodynamics of dabigatran etexilate, an oral direct thrombin inhibitor. Clin Appl Thromb Hemost 2009;15:9S-16S.
-
(2009)
Clin Appl Thromb Hemost
, vol.15
, pp. 9S-16S
-
-
Stangier, J.1
Clemens, A.2
-
12
-
-
17644400166
-
Pharmacokinetic profile of the oral direct thrombin inhibitor dabigatran etexilate in healthy volunteers and patients undergoing total hip replacement
-
Stangier J, Eriksson BI, Dahl OE, Ahnfelt L, Nehmiz G, Stahle H, Rathgen K, Svard R. Pharmacokinetic profile of the oral direct thrombin inhibitor dabigatran etexilate in healthy volunteers and patients undergoing total hip replacement. J Clin Pharmacol 2005;45:555-63.
-
(2005)
J Clin Pharmacol
, vol.45
, pp. 555-563
-
-
Stangier, J.1
Eriksson, B.I.2
Dahl, O.E.3
Ahnfelt, L.4
Nehmiz, G.5
Stahle, H.6
Rathgen, K.7
Svard, R.8
-
13
-
-
34548031359
-
The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects
-
Stangier J, Rathgen K, Stahle H, Gansser D, Roth W. The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects. Br J Clin Pharmacol 2007;64:292-303.
-
(2007)
Br J Clin Pharmacol
, vol.64
, pp. 292-303
-
-
Stangier, J.1
Rathgen, K.2
Stahle, H.3
Gansser, D.4
Roth, W.5
-
14
-
-
70349306707
-
Dabigatran versus warfarin in patients with atrial fibrillation
-
Connolly S, Ezekowitz M, Yusuf S, Eikelboom J, Oldgren J, Parekh A, Pogue J, Reilly PA, Themeles E, Varrone J, Wang S, Alings M, Xavier D, Zhu J, Diaz R, Lewis BS, Darius H, Diener HC, Joyner CD, Wallentin L, RE-LY Steering Committee and Investigators. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009;361:1139-51.
-
(2009)
N Engl J Med
, vol.361
, pp. 1139-1151
-
-
Connolly, S.1
Ezekowitz, M.2
Yusuf, S.3
Eikelboom, J.4
Oldgren, J.5
Parekh, A.6
Pogue, J.7
Reilly, P.A.8
Themeles, E.9
Varrone, J.10
Wang, S.11
Alings, M.12
Xavier, D.13
Zhu, J.14
Diaz, R.15
Lewis, B.S.16
Darius, H.17
Diener, H.C.18
Joyner, C.D.19
Wallentin, L.20
more..
-
15
-
-
71849117615
-
Dabigatran versus warfarin in the treatment of acute venous thromboembolism
-
Schulman S, Kearon C, Kakkar AK, Mismetti P, Schellong S, Eriksson H, Baanstra D, Schnee J, Goldhaber SZ, RE-COVER Study Group. Dabigatran versus warfarin in the treatment of acute venous thromboembolism. N Engl J Med 2009;361:2342-52.
-
(2009)
N Engl J Med
, vol.361
, pp. 2342-2352
-
-
Schulman, S.1
Kearon, C.2
Kakkar, A.K.3
Mismetti, P.4
Schellong, S.5
Eriksson, H.6
Baanstra, D.7
Schnee, J.8
Goldhaber, S.Z.9
-
17
-
-
84876459325
-
Novel anticoagulants and laboratory testing
-
Eby C. Novel anticoagulants and laboratory testing. Int J Lab Hematol 2013;35:262-8.
-
(2013)
Int J Lab Hematol
, vol.35
, pp. 262-268
-
-
Eby, C.1
-
18
-
-
84884985467
-
Clinical use of new oral anticoagulant drugs: dabigatran and rivaroxaban
-
Baglin T. Clinical use of new oral anticoagulant drugs: dabigatran and rivaroxaban. Br J Haematol 2013;163:160-7.
-
(2013)
Br J Haematol
, vol.163
, pp. 160-167
-
-
Baglin, T.1
-
19
-
-
34147189996
-
Drug-induced anti-factor VIII antibodies: a systemic review
-
Franchini M, Capra F, Nicolini N, Veneri D, Manzato F, Baudo F, Lippi G. Drug-induced anti-factor VIII antibodies: a systemic review. Med Sci Monit 2007;13:RA55-61.
-
(2007)
Med Sci Monit
, vol.13
, pp. RA55-RA61
-
-
Franchini, M.1
Capra, F.2
Nicolini, N.3
Veneri, D.4
Manzato, F.5
Baudo, F.6
Lippi, G.7
-
20
-
-
84856593171
-
Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatran
-
Stangier J, Feuring M. Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatran. Blood Coagul Fibrinolysis 2012;23:138-43.
-
(2012)
Blood Coagul Fibrinolysis
, vol.23
, pp. 138-143
-
-
Stangier, J.1
Feuring, M.2
-
21
-
-
84892791560
-
The acute management of haemorrhage, surgery and overdose in patients receiving dabigatran
-
Alikhan R, Rayment R, Keeling D, et al. The acute management of haemorrhage, surgery and overdose in patients receiving dabigatran. Emerg Med J 2014;2:163-8.
-
(2014)
Emerg Med J
, vol.2
, pp. 163-168
-
-
Alikhan, R.1
Rayment, R.2
Keeling, D.3
-
22
-
-
84876666915
-
Reversing dabigatran in life-threatening bleeding occurring during cardiac ablation with factor eight inhibitor bypassing activity
-
Dager WE, Gosselin RC, Roberts AJ. Reversing dabigatran in life-threatening bleeding occurring during cardiac ablation with factor eight inhibitor bypassing activity. Crit Care Med 2013;41:e42-6.
-
(2013)
Crit Care Med
, vol.41
, pp. e42-e46
-
-
Dager, W.E.1
Gosselin, R.C.2
Roberts, A.J.3
-
23
-
-
84897895391
-
How I treat target-specific oral anticoagulant-associated bleeding
-
Siegel DM, Gracia DA, Crowther MA. How I treat target-specific oral anticoagulant-associated bleeding. Blood 2014;123:1152-8.
-
(2014)
Blood
, vol.123
, pp. 1152-1158
-
-
Siegel, D.M.1
Gracia, D.A.2
Crowther, M.A.3
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