Sepsis affects most routine and cell population data (CPD) obtained using the Sysmex XN-2000 blood cell analyzer: Neutrophil-related CPD NE-SFL and NE-WY provide useful information for detecting sepsis

International Journal of Laboratory Hematology

Volumn 37, Issue 2, 2015, Pages 190-198

  Park, S H ^a,b   Park, C J ^c   Lee, B R ^c   Nam, K S ^c   Kim, M J ^c   Han, M Y ^c   Kim, Y J ^c   Cho, Y U ^c   Jang, S ^c  

^a Pusan National University School of Medicine   (South Korea)

^b Pusan National University School of Medicine   (South Korea)

^c University of Ulsan College of Medicine   (South Korea)

Author keywords

Cell population data; NE SFL; NE WY; Neutrophil; Sepsis; Sysmex XN 2000

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; HEMOGLOBIN; LACTIC ACID; PROCALCITONIN;

ARTICLE; CELL POPULATION; CELL POPULATION DATA; CONTROLLED STUDY; DISEASE SEVERITY; ERYTHROCYTE; FLUORESCENT LIGHT DISTRIBUTION WIDTH OF THE NEUTROPHIL AREA ON THE WHITE BLOOD CELL SCATTERGRAM; FLUORESCENT LIGHT INTENSITY OF THE NEUTROPHIL AREA ON WHITE BLOOD CELL DIFFERENTIAL SCATTERGRAM; FLUORESCENT LIGHTING; GRANULOCYTE; GRANULOCYTE COUNT; HEMATOCRIT; HEMATOLOGICAL PARAMETERS; HEMATOLOGY ANALYZER; HUMAN; IMMATURE GRANULOCYTE; LEUKOCYTE COUNT; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MORTALITY; NEUTROPHIL; NEUTROPHIL COUNT; PRIORITY JOURNAL; RED CELL DISTRIBUTION WIDTH; RETICULOCYTE COUNT; SEPSIS; SURVIVOR; BLOOD; BLOOD CELL COUNT; CASE CONTROL STUDY; DEVICES; PATHOLOGY; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; STANDARDS; TIME;

BIOMARKERS; BLOOD CELL COUNT; CASE-CONTROL STUDIES; HUMANS; NEUTROPHILS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SEPSIS; SEVERITY OF ILLNESS INDEX; TIME FACTORS;

EID: 84924762247     PISSN: 17515521     EISSN: 1751553X     Source Type: Journal    
DOI: 10.1111/ijlh.12261     Document Type: Article

References (12)

1. Müller B, Becker KL, Schächinger H, Rickenbacher PR, Huber PR, Zimmerli W, Ritz R. Calcitonin precursors are reliable markers of sepsis in a medical intensive care unit. Crit Care Med 2000;28:977-83.
2. Harbarth S, Holeckova K, Froidevaux C, Pittet D, Ricou B, Grau GE, Vadas L, Pugin J; Geneva Sepsis Network. Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically Ill patients admitted with suspected sepsis. Am J Respir Crit Care Med 2001;164:396-402.
3. Reinhart K, Bauer M, Riedemann NC, Hartog CS. New approaches to sepsis: molecular diagnostics and biomarkers. Clin Microbiol Rev 2012;25:609-34.
4. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992;101:1644-55.
5. Park BH, Kang YA, Park MS, Jung WJ, Lee SH, Lee SK, Kim SY, Kim SK, Chang J, Jung JY, Kim YS. Delta neutrophil index as an early marker of disease severity in critically ill patients with sepsis. BMC Infect Dis 2011;11:299.
6. Seok Y, Choi JR, Kim J, Kim YK, Lee J, Song J, Kim SJ, Lee KA. Delta neutrophil index: a promising diagnostic and prognostic marker for sepsis. Shock 2012;37:242-6.
7. Nahm CH, Choi JW, Lee J. Delta neutrophil index in automated immature granulocyte counts for assessing disease severity of patients with sepsis. Ann Clin Lab Sci 2008;38:241-6.
8. Park DH, Park K, Park J, Park HH, Chae H, Lim J, Oh EJ, Kim Y, Park YJ, Han K. Screening of sepsis using leukocyte cell population data from the Coulter automatic blood cell analyzer DxH800. Int J Lab Hematol 2011;33:391-9.
9. Luo Y, Lin J, Chen H, Zhang J, Peng S, Kuang M. Utility of neut-X, neut-Y and neut-Z parameters for rapidly assessing sepsis in tumor patients. Clin Chim Acta 2013;422:5-9.
10. Briggs C, Longair I, Kumar P, Singh D, Machin SJ. Performance evaluation of the Sysmex haematology XN modular system. J Clin Pathol 2012;65:1024-30.
11. Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G; SCCM, ESICM, ACCP, ATS, SIS. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003;31:1250-6.
12. Vincent JL. Clinical sepsis and septic shock-definition, diagnosis and management principles. Langenbecks Arch Surg 2008;393:817-24.