Orchidectomy enhances the expression of endothelin-1 and ETB receptors in rat portal vein

Journal of Smooth Muscle Research

Volumn 50, Issue 1, 2014, Pages 85-92

  de Rossignoli, Patrícia S ^a   De Labio, Roger W ^b   Payão, Spencer L M ^b   Pereira, Oduvaldo C M ^a   Chies, Agnaldo B ^b  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Endothelin 1; ETB receptor; Orchidectomy; Portal vein; Testosterone

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; TESTOSTERONE;

ANIMAL; ATROPHY; BLOOD; GENE EXPRESSION; GENETICS; MALE; ORCHIECTOMY; PATHOLOGY; PHYSIOLOGY; PORTAL VEIN; PROSTATE; RAT; SEMINAL VESICLE;

ANIMALS; ATROPHY; ENDOTHELIN-1; GENE EXPRESSION; MALE; ORCHIECTOMY; PORTAL VEIN; PROSTATE; RATS; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; SEMINAL VESICLES; TESTOSTERONE;

EID: 84924415403     PISSN: 09168737     EISSN: 18848796     Source Type: Journal    
DOI: 10.1540/jsmr.50.85     Document Type: Article

References (24)

1. Lopes RAM, Neves KB, Carneiro FS, Tostes RC. Testosterone and vascular function in aging. Front Physiol. 2012; 3: 89.
2. Bernini G, Versari D, Moretti A, Virdis A, Ghiadoni L, Bardini M. Vascular reactivity in congenital hypogonadal men before and after testosterone replacement therapy. J Clin Endocrinol Metab. 2006; 91(5): 1691-7.
3. Sader MA, Griffiths KA, Skilton MR, Wishart SM, Handelsman DJ, Celermajer DS. Physiological testosterone replacement and arterial endothelial function in men. Clin Endocrinol (Oxf). 2003; 59(1): 62-7.
4. Baum NH, Crespi CA. Testosterone replacement in elderly men. Geriatrics. 2007; 62(9): 15-8.
5. Seidman SN. Androgens and the aging male. Psychopharmacol Bull. 2007; 40(4): 205-18.
6. Hynes PG, Kelly K. Prostate cancer stem cells: The case for model systems. J Carcinog. 2012; 11: 6.
7. Polderman KH, Stehouwer CD, Van Kamp GJ, Dekker GA, Verheugt FW, Gooren LJ. Influence of sex hormones on plasma endothelin levels. Ann Intern Med. 1993; 118(6): 429-32.
8. van Kesteren PJ, Kooistra T, Lansink M, van Kamp GJ, Asscheman H, Gooren LJ, Emeis JJ, Vischer UM, Stehouwer CD. The effects of sex steroids on plasma levels of marker proteins of endothelial cell functioning. Thromb Haemost. 1998; 79(5): 1029-33.
9. Pearson LJ, Yandle TG, Nicholls MG, Evans JJ. Regulation of endothelin-1 release from human endothelial cells by sex steroids and angiotensin-II. Peptides. 2008; 29(6): 1057-61.
10. Ammar EM, Said SA, Hassan MS. Enhanced vasoconstriction and reduced vasorelaxation induced by testosterone and nandrolone in hypercholesterolemic rabbits. Pharmacol Res. 2004; 50(3): 253-9.
11. Kumanov P, Tomova A, Kirilov G. Testosterone replacement therapy in male hypogonadism is not associated with decrease of endotelin-1 levels. Int J Androl. 2007; 30(1): 41-7.
12. Rossignoli PS, Pereira OCM, Chies AB. Orchidectomy enhances the effects of phenylephrine in rat isolated portal vein. Clin Exp Pharmacol Physiol. 2010; 37(3): 368-74.
13. White RM, Rivera CO, Davison CA. Nitric oxide-dependent and-independent mechanisms account for gender differences in vasodilation to acetylcholine. J Pharmacol Exp Ther. 2000; 292(1): 375-80.
14. Valle RM, Abreu LC, Picarelli ZP, Valle JR. Influence of castration upon trophism and reactivity of rat seminal vesicles. Braz J Med Biol Res. 1982; 15(1): 49-53.
15. Yilmaz B, Canpolat S, Sandal S, Akpolat N, Kutlu S, Ilhan N, Kelestimur H. Paint thinner exposure inhibits testosterone synthesis and secretion in a reversible manner in the rat. Reprod Toxicol. 2006; 22(4): 791-6.
16. Matsuda K, Ruff A, Morinelli TA, Mathur RS, Halushka PV. Testosterone increases thromboxane A2 receptor density and responsiveness in rat aortas and platelets. Am J Physiol Heart Circ Physiol. 1994; 267(3): H887-93.
17. Henrion D, Laher I. Potentiation of norepinephrine-induced contractions by endothelin-1 in the rabbit aorta. Hypertension. 1993; 22(1): 78-83.
18. Thorin E, Cernacek P, Dupuis J. Endothelin-1 regulates tone of isolated small arteries in the rat: effect of hyperendothelinemia. Hypertension. 1998; 31(4): 1035-41.
19. Mazzuca MQ, Khalil RA. Vascular endothelin receptor type B: Structure, function and dysregulation in vascular disease. Biochem Pharmacol. 2012; 84(2): 147-62.
20. Takahashi W, Afiatpour P, Foster HE. The effect of castration on endothelins, their receptors and endothelin converting enzyme in rat prostate. Naunyn Schmiedebergs Arch Pharmacol. 2002; 366(2): 166-76.
21. Padley RJ, Dixon DB, Wu-Wong R. Effect of castration on endothelin receptors. ClinSci (Lond). 2002; 103 Suppl 48: 442S-445S.
22. Takahashi W, Yono M, Wada Y, Ikeda K, Weiss RM, Latifpour J. Regulatory effect of castration on endothelin, their receptors and endothelin-converting enzyme in rat seminal vesicle. BJU Int. 2003; 92(7): 803-9.
23. Hamzeh M, Robaire B. Identification of early response genes and pathway activated by androgens in the initial segment and caput regions of the regressed rat epididymis. Endocrinology. 2010; 151(9): 4504-14.
24. Kjekshus H, Risoe C, Scholz T, Smiseth OA. Methods for assessing hepatic distending pressure and changes in hepatic capacitance in pigs. Am J Physiol Heart Circ Physiol. 2000; 279(4): H1796-803.