Overexpression of E2F1 in human gastric carcinoma is involved in anti-cancer drug resistance

BMC Cancer

Volumn 14, Issue 1, 2014, Pages

  Yan, Lin Hai ^a   Wei, Wei Yuan ^b   Cao, Wen Long ^b   Zhang, Xiao Shi ^b   Xie, Yu Bo ^b   Xiao, Qiang ^b  

^a GUANGXI MEDICAL UNIVERSITY   (China)

^b FIRST AFFILIATED HOSPITAL OF GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

Drug resistance; E2F1 transcription factor; Gastric carcinoma; Lentiviral vector; Murine model

Indexed keywords

CASPASE 3; CASPASE 9; CISPLATIN; DOXORUBICIN; EOSIN; FLUOROURACIL; HEMATOXYLIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN P53; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR ZEB1; ABCB1 PROTEIN, HUMAN; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIBIOTIC; DNA BINDING PROTEIN; E2F1 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; MEOX2 PROTEIN, HUMAN; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1; NUCLEAR PROTEIN; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN P73; ZEB1 PROTEIN, HUMAN; ZEB2 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARCINOMA CELL LINE; CELL CYCLE PROGRESSION; CELL GROWTH; CONTROLLED STUDY; DRUG TRANSPORT; FLOW CYTOMETRY; GAX GENE; GENE; GENE EXPRESSION REGULATION; HUMAN; IC50; IN VITRO STUDY; IN VIVO STUDY; MALE; MDR1 GENE; MOLECULAR DYNAMICS; MOUSE; MRP GENE; MULTIDRUG RESISTANCE; NICK END LABELING; NONHUMAN; NUDE MOUSE; PROTEIN EXPRESSION; PROTEIN FUNCTION; S PHASE CELL CYCLE CHECKPOINT; STOMACH ADENOCARCINOMA; STOMACH CARCINOMA; TAP73 GENE; TUMOR VOLUME; UPREGULATION; WESTERN BLOTTING; ZEB1 GENE; ZEB2 GENE; ANIMAL; BAGG ALBINO MOUSE; CARCINOMA; DRUG RESISTANCE; GENETICS; METABOLISM; STOMACH NEOPLASMS; TUMOR CELL LINE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA; CELL LINE, TUMOR; CISPLATIN; DNA-BINDING PROTEINS; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; E2F1 TRANSCRIPTION FACTOR; HOMEODOMAIN PROTEINS; HUMANS; INHIBITORY CONCENTRATION 50; MALE; MICE; MICE, INBRED BALB C; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NUCLEAR PROTEINS; P-GLYCOPROTEINS; REPRESSOR PROTEINS; STOMACH NEOPLASMS; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 84924373949     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-904     Document Type: Article

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