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Volumn 84, Issue 10, 2015, Pages 981-988

Autologous hematopoietic stem cell transplantation in multiple sclerosis

(22)  Mancardi, Giovanni L a   Sormani, Maria P a   Gualandi, Francesca b   Saiz, Albert c   Carreras, Eric c   Merelli, Elisa d   Donelli, Amedea d   Lugaresi, Alessandra e   Di Bartolomeo, Paolo f   Rottoli, Maria R g   Rambaldi, Alessandro h   Amato, Maria P i   Massacesi, Luca i   Di Gioia, Massimo i   Vuolo, Luisa i   Currò, Daniela a   Roccatagliata, Luca a   Filippi, Massimo j   Aguglia, Umberto k   Iacopino, Pasquale l   more..


Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; CARMUSTINE; COTRIMOXAZOLE; CYCLOPHOSPHAMIDE; CYTARABINE; ETOPOSIDE; FILGRASTIM; GADOLINIUM; MELPHALAN; METHYLPREDNISOLONE; MITOXANTRONE; ANTINEOPLASTIC AGENT;

EID: 84924368416     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000001329     Document Type: Article
Times cited : (204)

References (39)
  • 1
    • 0345669108 scopus 로고
    • Rationale for bone marrow transplantation in the treatment of autoimmune diseases
    • Ikehara S, Good RA, Nakamura T, et al. Rationale for bone marrow transplantation in the treatment of autoimmune diseases. Proc Natl Acad Sci USA 1985;82:2483-2487.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 2483-2487
    • Ikehara, S.1    Good, R.A.2    Nakamura, T.3
  • 2
    • 0024791136 scopus 로고
    • Regression of adjuvant-induced arthritis in rats following bone marrow transplantation
    • Van Bekkum DW, Bohre EP, Houben PF, Knaan-Shanzer S. Regression of adjuvant-induced arthritis in rats following bone marrow transplantation. Proc Natl Acad Sci USA 1989;86: 10090-10094.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 10090-10094
    • Van Bekkum, D.W.1    Bohre, E.P.2    Houben, P.F.3    Knaan-Shanzer, S.4
  • 3
    • 0028118606 scopus 로고
    • Immune ablation followed by allogeneic or autologous bone marrow transplantation: A new treatment for severe autoimmune diseases?
    • Marmont AM. Immune ablation followed by allogeneic or autologous bone marrow transplantation: a new treatment for severe autoimmune diseases? Stem Cells 1994;12: 125-135.
    • (1994) Stem Cells , vol.12 , pp. 125-135
    • Marmont, A.M.1
  • 4
    • 20144386375 scopus 로고    scopus 로고
    • Thymic output generates a new and diverse TCR repertoire after autolo-gous stem cell transplantation in multiple sclerosis patients
    • Muraro PA, Douek DC, Packer A, et al. Thymic output generates a new and diverse TCR repertoire after autolo-gous stem cell transplantation in multiple sclerosis patients. J Exp Med 2005;201:805-816.
    • (2005) J Exp Med , vol.201 , pp. 805-816
    • Muraro, P.A.1    Douek, D.C.2    Packer, A.3
  • 5
    • 59449092041 scopus 로고    scopus 로고
    • Depletion of autor-eactive immunologic memory followed by autologous stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system
    • Alexander T, Thiel A, Rosen O, et al. Depletion of autor-eactive immunologic memory followed by autologous stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system. Blood 2009;113:214-223.
    • (2009) Blood , vol.113 , pp. 214-223
    • Alexander, T.1    Thiel, A.2    Rosen, O.3
  • 6
    • 78650327841 scopus 로고    scopus 로고
    • Resetting autoimmunity in the nervous system: The role of hematopoietic stem cell transplantation
    • Muraro PA, Abrahamsson SV. Resetting autoimmunity in the nervous system: the role of hematopoietic stem cell transplantation. Curr Opin Investig Drugs 2010;11: 1265-1275.
    • (2010) Curr Opin Investig Drugs , vol.11 , pp. 1265-1275
    • Muraro, P.A.1    Abrahamsson, S.V.2
  • 7
    • 84876479682 scopus 로고    scopus 로고
    • Diminished Th17 (Not Th1) responses underline multiple sclerosis disease abrogation after hematopoietic stem cell transplantation
    • Darlington P, Touil T, Doucet J, et al. Diminished Th17 (Not Th1) responses underline multiple sclerosis disease abrogation after hematopoietic stem cell transplantation. Ann Neurol 2013;73:341-354.
    • (2013) Ann Neurol , vol.73 , pp. 341-354
    • Darlington, P.1    Touil, T.2    Doucet, J.3
  • 8
    • 84883442367 scopus 로고    scopus 로고
    • Non-myeloablative autologous haematopoietic stem cell transplantation expands regulatory cells and depletes IL-17 producing mucosal-associated invariant T cells in multiples sclerosis
    • Abrahamsson SV, Angelini DF, Dubinsky AN, et al. Non-myeloablative autologous haematopoietic stem cell transplantation expands regulatory cells and depletes IL-17 producing mucosal-associated invariant T cells in multiples sclerosis. Brain 2013;136:2888-2903.
    • (2013) Brain , vol.136 , pp. 2888-2903
    • Abrahamsson, S.V.1    Angelini, D.F.2    Dubinsky, A.N.3
  • 9
    • 84896775850 scopus 로고    scopus 로고
    • T cell repertoire following autologous stem cell transplantation for multiple sclerosis
    • Muraro P, Robins H, Malhotra S, et al. T cell repertoire following autologous stem cell transplantation for multiple sclerosis. J Clin Invest 2014;124:1168-1172.
    • (2014) J Clin Invest , vol.124 , pp. 1168-1172
    • Muraro, P.1    Robins, H.2    Malhotra, S.3
  • 10
    • 76549116862 scopus 로고    scopus 로고
    • Autologous hema-topoietic stem cell transplantation for autoimmune diseases: An observational study on 12 years' experience from the European Group for Blood and Marrow Transplantation Working Party on Autoimmune Diseases
    • Farge D, Labopin M, Tyndall A, et al. Autologous hema-topoietic stem cell transplantation for autoimmune diseases: an observational study on 12 years' experience from the European Group for Blood and Marrow Transplantation Working Party on Autoimmune Diseases. Hae-matologica 2010;95:284-292.
    • (2010) Hae-matologica , vol.95 , pp. 284-292
    • Farge, D.1    Labopin, M.2    Tyndall, A.3
  • 11
    • 84862184679 scopus 로고    scopus 로고
    • Haematopoietic SCT in severe autoimmune diseases: Updated guidelines of the European Group for Blood and Marrow Transplantation
    • Snowden JA, Saccardi R, Allez M, et al. Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant 2012;47:770-790.
    • (2012) Bone Marrow Transplant , vol.47 , pp. 770-790
    • Snowden, J.A.1    Saccardi, R.2    Allez, M.3
  • 12
    • 0030714110 scopus 로고    scopus 로고
    • Peripheral blood stem cell transplantation in the treatment of progressive multiple sclerosis: First results of a pilot study
    • Fassas A, Anagnostopoulos A, Kazis A, et al. Peripheral blood stem cell transplantation in the treatment of progressive multiple sclerosis: first results of a pilot study. Bone Marrow Transplant 1997;20:631-638.
    • (1997) Bone Marrow Transplant , vol.20 , pp. 631-638
    • Fassas, A.1    Anagnostopoulos, A.2    Kazis, A.3
  • 13
    • 0141816715 scopus 로고    scopus 로고
    • High-dose immunosuppressive therapy and autologous peripheral blood stem cell transplantation for severe multiple sclerosis
    • Nash RA, Bowen JD, McSweeney PA, et al. High-dose immunosuppressive therapy and autologous peripheral blood stem cell transplantation for severe multiple sclerosis. Blood 2003;102:2364-2372.
    • (2003) Blood , vol.102 , pp. 2364-2372
    • Nash, R.A.1    Bowen, J.D.2    McSweeney, P.A.3
  • 14
    • 20144368500 scopus 로고    scopus 로고
    • Autologous HSCT for severe progressive multiple sclerosis in a multi-center trial: Impact on disease activity and quality of life
    • Saccardi R, Mancardi GL, Solari A, et al. Autologous HSCT for severe progressive multiple sclerosis in a multi-center trial: impact on disease activity and quality of life. Blood 2005;105:2601-2607.
    • (2005) Blood , vol.105 , pp. 2601-2607
    • Saccardi, R.1    Mancardi, G.L.2    Solari, A.3
  • 15
    • 0034060611 scopus 로고    scopus 로고
    • High-dose immu-nosuppressive therapy with PBPC support in the treatment of poor risk multiple sclerosis
    • Kozák T, Havrdová E, Pit'ha J, et al. High-dose immu-nosuppressive therapy with PBPC support in the treatment of poor risk multiple sclerosis. Bone Marrow Transplant 2000;25:525-531.
    • (2000) Bone Marrow Transplant , vol.25 , pp. 525-531
    • Kozák, T.1    Havrdová, E.2    Pit'Ha, J.3
  • 16
    • 33750345757 scopus 로고    scopus 로고
    • Autologous peripheral blood stem cell transplantation for severe multiple sclerosis
    • Su L, Xu J, Ji BX, et al. Autologous peripheral blood stem cell transplantation for severe multiple sclerosis. Int J Hematol 2006;84:276-281.
    • (2006) Int J Hematol , vol.84 , pp. 276-281
    • Su, L.1    Xu, J.2    Ji, B.X.3
  • 17
    • 33745627452 scopus 로고    scopus 로고
    • Autolo-gous hematopoietic stem cell transplantation for progressive multiple sclerosis: Report of efficacy and safety at three yr of follow up in 21 patients
    • Ni XS, Ouyang J, Zhu WH, Wang C, Chen B. Autolo-gous hematopoietic stem cell transplantation for progressive multiple sclerosis: report of efficacy and safety at three yr of follow up in 21 patients. Clin Transplant 2006;20: 485-489.
    • (2006) Clin Transplant , vol.20 , pp. 485-489
    • Ni, X.S.1    Ouyang, J.2    Zhu, W.H.3    Wang, C.4    Chen, B.5
  • 18
    • 84867405187 scopus 로고    scopus 로고
    • Autolo-gous hematopoietic stem cell transplantation with reduced-intensity conditioning in multiple sclerosis
    • Shevchenko JL, Kuznetsov AN, Ionova TI, et al. Autolo-gous hematopoietic stem cell transplantation with reduced-intensity conditioning in multiple sclerosis. Exp Hematol 2012;40:892-898.
    • (2012) Exp Hematol , vol.40 , pp. 892-898
    • Shevchenko, J.L.1    Kuznetsov, A.N.2    Ionova, T.I.3
  • 19
    • 20144364694 scopus 로고    scopus 로고
    • Autologous stem cell transplantation as rescue therapy in malignant forms of multiple sclerosis
    • Mancardi GL, Murialdo A, Rossi P, et al. Autologous stem cell transplantation as rescue therapy in malignant forms of multiple sclerosis. Mult Scler 2005;11:367-371.
    • (2005) Mult Scler , vol.11 , pp. 367-371
    • Mancardi, G.L.1    Murialdo, A.2    Rossi, P.3
  • 20
    • 43149097417 scopus 로고    scopus 로고
    • Autologous stem-cell transplantation in malignant multiple sclerosis: A case with a favorable long-term outcome
    • Kimiskidis V, Sakellari I, Tsimourtou V, et al. Autologous stem-cell transplantation in malignant multiple sclerosis: a case with a favorable long-term outcome. Mult Scler 2008; 14:278-283.
    • (2008) Mult Scler , vol.14 , pp. 278-283
    • Kimiskidis, V.1    Sakellari, I.2    Tsimourtou, V.3
  • 21
    • 84908335130 scopus 로고    scopus 로고
    • Autologous haematopoietic stem cell transplantation for aggressive multiple sclerosis. The Swedish experience
    • Burman J, Iacobaeus E, Svenningsson A, et al. Autologous haematopoietic stem cell transplantation for aggressive multiple sclerosis. The Swedish experience. J Neurol Neu-rosurg 2014;85:1116-1121.
    • (2014) J Neurol Neu-rosurg , vol.85 , pp. 1116-1121
    • Burman, J.1    Iacobaeus, E.2    Svenningsson, A.3
  • 22
    • 34250648076 scopus 로고    scopus 로고
    • Autologous hematopoietic stem cell transplantation for very active relapsing-remitting multiple sclerosis: Report of two cases
    • Portaccio E, Amato MP, Siracusa G, et al. Autologous hematopoietic stem cell transplantation for very active relapsing-remitting multiple sclerosis: report of two cases. Mult Scler 2007;13:676-678.
    • (2007) Mult Scler , vol.13 , pp. 676-678
    • Portaccio, E.1    Amato, M.P.2    Siracusa, G.3
  • 23
    • 0020686503 scopus 로고
    • New diagnostic criteria for multiple sclerosis: Guidelines for research protocols
    • Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983;13:227-231.
    • (1983) Ann Neurol , vol.13 , pp. 227-231
    • Poser, C.M.1    Paty, D.W.2    Scheinberg, L.3
  • 24
    • 0031040238 scopus 로고    scopus 로고
    • Therapeutic effect of mitoxantrone combined with methylprednisolone in multiple sclerosis: A randomised multicentre study of active disease using MRI and clinical criteria
    • Edan G, Miller D, Clanet M, et al. Therapeutic effect of mitoxantrone combined with methylprednisolone in multiple sclerosis: a randomised multicentre study of active disease using MRI and clinical criteria. J Neurol Neuro-surg Psychiatry 1997;62:112-118.
    • (1997) J Neurol Neuro-surg Psychiatry , vol.62 , pp. 112-118
    • Edan, G.1    Miller, D.2    Clanet, M.3
  • 25
    • 0035838312 scopus 로고    scopus 로고
    • Autologous hematopoietic stem cell transplantation suppresses Gd-enhanced MRI activity in MS
    • Mancardi GL, Saccardi R, Filippi M, et al. Autologous hematopoietic stem cell transplantation suppresses Gd-enhanced MRI activity in MS. Neurology 2001;57:62-68.
    • (2001) Neurology , vol.57 , pp. 62-68
    • Mancardi, G.L.1    Saccardi, R.2    Filippi, M.3
  • 26
    • 0842347341 scopus 로고    scopus 로고
    • Clinical and MRI outcome after autologous hematopoietic stem cell transplantation in MS
    • Saiz A, Blanco Y, Carreras E, et al. Clinical and MRI outcome after autologous hematopoietic stem cell transplantation in MS. Neurology 2004;62:282-284.
    • (2004) Neurology , vol.62 , pp. 282-284
    • Saiz, A.1    Blanco, Y.2    Carreras, E.3
  • 27
    • 59649121664 scopus 로고    scopus 로고
    • Use of mitoxan-trone in early multiple sclerosis with malignant disease course: Observational study in 30 patients with clinical and MRI outcomes after one year
    • Ory S, Debouverie M, Le Page E, et al. Use of mitoxan-trone in early multiple sclerosis with malignant disease course: observational study in 30 patients with clinical and MRI outcomes after one year. Rev Neurol 2008;164: 1028-1034.
    • (2008) Rev Neurol , vol.164 , pp. 1028-1034
    • Ory, S.1    Debouverie, M.2    Le Page, E.3
  • 28
    • 49949094900 scopus 로고    scopus 로고
    • Immune ablation and autologous stem cell transplantation for aggressive multiple sclerosis: Interim 5 year report
    • Freedman MS, Atkins DL, Arnold A, et al. Immune ablation and autologous stem cell transplantation for aggressive multiple sclerosis: interim 5 year report. Mult Scler 2007; 13:S22. Abstract.
    • (2007) Mult Scler , vol.13 , pp. S22
    • Freedman, M.S.1    Atkins, D.L.2    Arnold, A.3
  • 29
    • 0037153729 scopus 로고    scopus 로고
    • Mitoxantrone in progressive multiple sclerosis: A placebo-controlled, double blind, randomised, multicentre trial
    • Hartung HP, Gonsette R, Konig N, et al. Mitoxantrone in progressive multiple sclerosis: a placebo-controlled, double blind, randomised, multicentre trial. Lancet 2002;360: 2018-2025.
    • (2002) Lancet , vol.360 , pp. 2018-2025
    • Hartung, H.P.1    Gonsette, R.2    Konig, N.3
  • 30
    • 31544467633 scopus 로고    scopus 로고
    • The window of therapeutic opportunity in multiple sclerosis: Evidence from monoclonal antibody therapy
    • Coles AJ, Cox A, Le Page E, et al. The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy. J Neurol 2006;253:98-108.
    • (2006) J Neurol , vol.253 , pp. 98-108
    • Coles, A.J.1    Cox, A.2    Le Page, E.3
  • 31
    • 60049083956 scopus 로고    scopus 로고
    • Autologous non-myeloablative haemopoietic stem cell transplantation in relapsing-remitting multiple sclerosis: A phase I/II study
    • Burt RK, Loh Y, Cohen B, et al. Autologous non-myeloablative haemopoietic stem cell transplantation in relapsing-remitting multiple sclerosis: a phase I/II study. Lancet Neurol 2009;8:244-253.
    • (2009) Lancet Neurol , vol.8 , pp. 244-253
    • Burt, R.K.1    Loh, Y.2    Cohen, B.3
  • 32
    • 77953735863 scopus 로고    scopus 로고
    • High-dose im-munoablation with autologous haematopoietic stem cell transplantation in aggressive multiple sclerosis: A single centre 10-year experience
    • Krasulová E, Trneny M, Kozák T, et al. High-dose im-munoablation with autologous haematopoietic stem cell transplantation in aggressive multiple sclerosis: a single centre 10-year experience. Mult Scler 2010;16:685-693.
    • (2010) Mult Scler , vol.16 , pp. 685-693
    • Krasulová, E.1    Trneny, M.2    Kozák, T.3
  • 33
    • 79953208669 scopus 로고    scopus 로고
    • Long-term results of stem cell transplantation for MS: A single-center experience
    • Fassas A, Kimiskidis VK, Sakellari I, et al. Long-term results of stem cell transplantation for MS: a single-center experience. Neurology 2011;76:1066-1070.
    • (2011) Neurology , vol.76 , pp. 1066-1070
    • Fassas, A.1    Kimiskidis, V.K.2    Sakellari, I.3
  • 34
    • 84861811380 scopus 로고    scopus 로고
    • Autolo-gous haematopoietic stem cell transplantation with an intermediate intensity conditioning regimen in multiple sclerosis: The Italian multi-centre experience
    • Mancardi GL, Sormani MP, Di Gioia M, et al. Autolo-gous haematopoietic stem cell transplantation with an intermediate intensity conditioning regimen in multiple sclerosis: the Italian multi-centre experience. Mult Scler 2012;18:835-842.
    • (2012) Mult Scler , vol.18 , pp. 835-842
    • Mancardi, G.L.1    Sormani, M.P.2    Di Gioia, M.3
  • 35
    • 84863727030 scopus 로고    scopus 로고
    • Autologous hae matopoietic stem cell Transplantation following high-dose immunosuppressive therapy for advanced multiple sclero sis: Long-term results
    • Bowen JD, Kraft GH, Wundes A, et al. Autologous hae matopoietic stem cell Transplantation following high-dose immunosuppressive therapy for advanced multiple sclero sis: long-term results. Bone Marrow Transplant 2012;47: 946-951.
    • (2012) Bone Marrow Transplant , vol.47 , pp. 946-951
    • Bowen, J.D.1    Kraft, G.H.2    Wundes, A.3
  • 36
    • 0141593519 scopus 로고    scopus 로고
    • Hematopoietic stem cell transplantation for progressive multiple sclerosis: Failure of a total body irradiation-based conditioning regimen to prevent disease progression in patients with high disability scores
    • Burt RK, Cohen BA, Russell E, et al. Hematopoietic stem cell transplantation for progressive multiple sclerosis: failure of a total body irradiation-based conditioning regimen to prevent disease progression in patients with high disability scores. Blood 2003;102:2373-2378.
    • (2003) Blood , vol.102 , pp. 2373-2378
    • Burt, R.K.1    Cohen, B.A.2    Russell, E.3
  • 37
    • 84879017576 scopus 로고    scopus 로고
    • MRI lesions as a surrogate for relapses in multiple sclerosis: A meta-analysis of randomized trials
    • Sormani MP, Bruzzi P. MRI lesions as a surrogate for relapses in multiple sclerosis: a meta-analysis of randomized trials. Lancet Neurol 2013;12:669-676.
    • (2013) Lancet Neurol , vol.12 , pp. 669-676
    • Sormani, M.P.1    Bruzzi, P.2
  • 38
    • 77955137180 scopus 로고    scopus 로고
    • Surrogate endpoints for EDSS worsening in multiple sclerosis: A meta-analytic approach
    • Sormani MP, Bonzano L, Roccatagliata L, et al. Surrogate endpoints for EDSS worsening in multiple sclerosis: a meta-analytic approach. Neurology 2010;75:302-309.
    • (2010) Neurology , vol.75 , pp. 302-309
    • Sormani, M.P.1    Bonzano, L.2    Roccatagliata, L.3
  • 39
    • 84861802589 scopus 로고    scopus 로고
    • A prospective randomized controlled trial of autologous haematopoietic stem cell transplantation for aggressive multiple sclerosis: A position paper
    • Saccardi R, Freedman MS, Sormani MP, et al; European Blood and Marrow Transplantation Group, Center for International Blood and Marrow Research, HSCT in MS International Study Group. A prospective, randomized, controlled trial of autologous haematopoietic stem cell transplantation for aggressive multiple sclerosis: a position paper. Mult Scler 2012;18:825-834.
    • (2012) Mult Scler , vol.18 , pp. 825-834
    • Saccardi, R.1    Freedman, M.S.2    Sormani, M.P.3


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