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Volumn 33, Issue 4, 2015, Pages 448-454

Efficacy and safety of odanacatib treatment for patients with osteoporosis: a meta-analysis

Author keywords

Bone mineral density; Meta analysis; Odanacatib; Osteoporosis; Safety

Indexed keywords

ALENDRONIC ACID; ODANACATIB; BIPHENYL DERIVATIVE; BONE DENSITY CONSERVATION AGENT;

EID: 84924364538     PISSN: 09148779     EISSN: 14355604     Source Type: Journal    
DOI: 10.1007/s00774-014-0609-3     Document Type: Article
Times cited : (15)

References (25)
  • 1
    • 84982286925 scopus 로고    scopus 로고
    • Clinician’s guide to prevention and treatment of osteoporosis
    • National Osteoporosis Foundation (2010) Clinician’s guide to prevention and treatment of osteoporosis. Available at: http://www.nof.org/sites/default/files/pdfs/NOF_ClinicianGuide2009_v7pdf
    • (2010) Available at:
  • 2
    • 33750209491 scopus 로고    scopus 로고
    • An estimate of the worldwide prevalence and disability associated with osteoporotic fractures
    • COI: 1:STN:280:DC%2BD28nitVSksQ%3D%3D, PID: 16983459
    • Johnell O, Kanis JA (2006) An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int 17:1726–1733
    • (2006) Osteoporos Int , vol.17 , pp. 1726-1733
    • Johnell, O.1    Kanis, J.A.2
  • 3
    • 33745700042 scopus 로고    scopus 로고
    • Less frequent dosing of bisphosphonates in osteoporosis: focus on ibandronate
    • COI: 1:CAS:528:DC%2BD28XnsFGhsbc%3D, PID: 16846543
    • Simonelli C, Burke MS (2006) Less frequent dosing of bisphosphonates in osteoporosis: focus on ibandronate. Curr Med Res Opin 22:1101–1108
    • (2006) Curr Med Res Opin , vol.22 , pp. 1101-1108
    • Simonelli, C.1    Burke, M.S.2
  • 4
    • 84863116822 scopus 로고    scopus 로고
    • Odanacatib treatment increases hip bone mass and cortical thickness by preserving endocortical bone formation and stimulating periosteal bone formation in the ovariectomized adult rhesus monkey
    • COI: 1:CAS:528:DC%2BC38XisFejt7o%3D, PID: 22113921
    • Cusick T, Chen CM, Pennypacker BL, Pickarski M, Kimmel DB et al (2012) Odanacatib treatment increases hip bone mass and cortical thickness by preserving endocortical bone formation and stimulating periosteal bone formation in the ovariectomized adult rhesus monkey. J Bone Miner Res 27:524–537
    • (2012) J Bone Miner Res , vol.27 , pp. 524-537
    • Cusick, T.1    Chen, C.M.2    Pennypacker, B.L.3    Pickarski, M.4    Kimmel, D.B.5
  • 5
    • 84863116889 scopus 로고    scopus 로고
    • Odanacatib reduces bone turnover and increases bone mass in the lumbar spine of skeletally mature ovariectomized rhesus monkeys
    • COI: 1:CAS:528:DC%2BC38XisFejtL8%3D, PID: 22113859
    • Masarachia PJ, Pennypacker BL, Pickarski M, Scott KR, Wesolowski GA et al (2012) Odanacatib reduces bone turnover and increases bone mass in the lumbar spine of skeletally mature ovariectomized rhesus monkeys. J Bone Miner Res 27:509–523
    • (2012) J Bone Miner Res , vol.27 , pp. 509-523
    • Masarachia, P.J.1    Pennypacker, B.L.2    Pickarski, M.3    Scott, K.R.4    Wesolowski, G.A.5
  • 6
    • 77953510486 scopus 로고    scopus 로고
    • Odanacatib, a cathepsin-K inhibitor for osteoporosis: a two-year study in postmenopausal women with low bone density
    • PID: 19874198
    • Bone HG, McClung MR, Roux C, Recker RR, Eisman JA et al (2010) Odanacatib, a cathepsin-K inhibitor for osteoporosis: a two-year study in postmenopausal women with low bone density. J Bone Miner Res 25:937–947
    • (2010) J Bone Miner Res , vol.25 , pp. 937-947
    • Bone, H.G.1    McClung, M.R.2    Roux, C.3    Recker, R.R.4    Eisman, J.A.5
  • 7
    • 84873684246 scopus 로고    scopus 로고
    • Bone density, turnover, and estimated strength in postmenopausal women treated with odanacatib: a randomized trial
    • COI: 1:CAS:528:DC%2BC3sXjtlOks74%3D, PID: 23337728
    • Brixen K, Chapurlat R, Cheung AM, Keaveny TM, Fuerst T et al (2013) Bone density, turnover, and estimated strength in postmenopausal women treated with odanacatib: a randomized trial. J Clin Endocrinol Metab 98:571–580
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. 571-580
    • Brixen, K.1    Chapurlat, R.2    Cheung, A.M.3    Keaveny, T.M.4    Fuerst, T.5
  • 8
    • 84891839676 scopus 로고    scopus 로고
    • Effect of the cathepsin K inhibitor odanacatib administered once weekly on bone mineral density in Japanese patients with osteoporosis—a double-blind, randomized, dose-finding study
    • COI: 1:CAS:528:DC%2BC2cXjtlCksQ%3D%3D, PID: 23716037
    • Nakamura T, Shiraki M, Fukunaga M, Tomomitsu T, Santora AC et al (2014) Effect of the cathepsin K inhibitor odanacatib administered once weekly on bone mineral density in Japanese patients with osteoporosis—a double-blind, randomized, dose-finding study. Osteoporos Int 25:367–376
    • (2014) Osteoporos Int , vol.25 , pp. 367-376
    • Nakamura, T.1    Shiraki, M.2    Fukunaga, M.3    Tomomitsu, T.4    Santora, A.C.5
  • 9
    • 84889847492 scopus 로고    scopus 로고
    • Effects of odanacatib on BMD and safety in the treatment of osteoporosis in postmenopausal women previously treated with alendronate: a randomized placebo-controlled trial
    • COI: 1:CAS:528:DC%2BC3sXhvF2ksrzK, PID: 24064689
    • Bonnick S, De Villiers T, Odio A, Palacios S, Chapurlat R et al (2013) Effects of odanacatib on BMD and safety in the treatment of osteoporosis in postmenopausal women previously treated with alendronate: a randomized placebo-controlled trial. J Clin Endocrinol Metab 98:4727–4735
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. 4727-4735
    • Bonnick, S.1    De Villiers, T.2    Odio, A.3    Palacios, S.4    Chapurlat, R.5
  • 10
    • 68049137869 scopus 로고    scopus 로고
    • The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration
    • PID: 19621070
    • Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC et al (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med 6:e1000100
    • (2009) PLoS Med , vol.6 , pp. e1000100
    • Liberati, A.1    Altman, D.G.2    Tetzlaff, J.3    Mulrow, C.4    Gøtzsche, P.C.5
  • 11
    • 84859001212 scopus 로고    scopus 로고
    • The Cochrane collaboration’s tool for assessing risk of bias in randomised trials
    • PID: 22008217
    • Higgins JP, Altman DG, Gøtzsche PC, Jüni P, Moher D et al (2011) The Cochrane collaboration’s tool for assessing risk of bias in randomised trials. BMJ 343:d5928
    • (2011) BMJ , vol.343 , pp. d5928
    • Higgins, J.P.1    Altman, D.G.2    Gøtzsche, P.C.3    Jüni, P.4    Moher, D.5
  • 12
    • 85100415918 scopus 로고    scopus 로고
    • Cochrane handbook for systematic reviews of interventions 4.2.6
    • Wiley, Chichester (updated September
    • Higgins JP, Green S (eds) (2006) Cochrane handbook for systematic reviews of interventions 4.2.6. In: The Cochrane Library, Issue 4. Wiley, Chichester (updated September 2006)
    • (2006) The Cochrane Library, Issue , vol.4 , pp. 2006
    • Higgins, J.P.1
  • 13
    • 33745773090 scopus 로고    scopus 로고
    • Comparison of weekly treatment of postmenopausal osteoporosis with alendronate versus risedronate over two years
    • COI: 1:CAS:528:DC%2BD28XntFWgtL4%3D, PID: 16636120
    • Bonnick S, Saag KG, Kiel DP, McClung M, Hochberg M et al (2006) Comparison of weekly treatment of postmenopausal osteoporosis with alendronate versus risedronate over two years. J Clin Endocrinol Metab 91:2631–2637
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 2631-2637
    • Bonnick, S.1    Saag, K.G.2    Kiel, D.P.3    McClung, M.4    Hochberg, M.5
  • 14
    • 40449130463 scopus 로고    scopus 로고
    • A comparison of the effect of alendronate and risedronate on bone mineral density in postmenopausal women with osteoporosis: 24-month results from FACTS-international
    • COI: 1:CAS:528:DC%2BC3cXktFGgtbw%3D, PID: 18324951
    • Reid DM, Hosking D, Kendler D, Brandi ML, Wark JD et al (2008) A comparison of the effect of alendronate and risedronate on bone mineral density in postmenopausal women with osteoporosis: 24-month results from FACTS-international. Int J Clin Pract 62:575–584
    • (2008) Int J Clin Pract , vol.62 , pp. 575-584
    • Reid, D.M.1    Hosking, D.2    Kendler, D.3    Brandi, M.L.4    Wark, J.D.5
  • 15
    • 0034097152 scopus 로고    scopus 로고
    • Therapeutic equivalence of alendronate 70 mg once weekly and alendronate 10 mg daily in the treatment of osteoporosis
    • COI: 1:CAS:528:DC%2BD3cXitVCns7g%3D
    • Schnitzer T, Bone HG, Crepaldi G, Adami S, McClung M et al (2000) Therapeutic equivalence of alendronate 70 mg once weekly and alendronate 10 mg daily in the treatment of osteoporosis. Aging Clin Exp Res 12:1–12
    • (2000) Aging Clin Exp Res , vol.12
    • Schnitzer, T.1    Bone, H.G.2    Crepaldi, G.3    Adami, S.4    McClung, M.5
  • 16
    • 3242762388 scopus 로고    scopus 로고
    • Differential effects of teriparatide on BMD after treatment with raloxifene or alendronate
    • COI: 1:CAS:528:DC%2BD2cXktFGksrk%3D, PID: 15068497
    • Ettinger B, San Martin J, Crans G, Pavo I (2004) Differential effects of teriparatide on BMD after treatment with raloxifene or alendronate. J Bone Miner Res 19:745–751
    • (2004) J Bone Miner Res , vol.19 , pp. 745-751
    • Ettinger, B.1    San Martin, J.2    Crans, G.3    Pavo, I.4
  • 17
    • 53749105039 scopus 로고    scopus 로고
    • Early responsiveness of women with osteoporosis to teriparatide after therapy with alendronate or risedronate
    • COI: 1:CAS:528:DC%2BD1cXht1Gmur%2FN, PID: 18682511
    • Miller PD, Delmas PD, Lindsay R, Watts NB, Luckey M et al (2008) Early responsiveness of women with osteoporosis to teriparatide after therapy with alendronate or risedronate. J Clin Endocrinol Metab 93:3785–3793
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 3785-3793
    • Miller, P.D.1    Delmas, P.D.2    Lindsay, R.3    Watts, N.B.4    Luckey, M.5
  • 18
    • 40849124001 scopus 로고    scopus 로고
    • Effects of prior antiresorptive therapy on the bone mineral density response to two years of teriparatide treatment in postmenopausal women with osteoporosis
    • COI: 1:CAS:528:DC%2BD1cXjsFynurg%3D, PID: 18160462
    • Boonen S, Marin F, Obermayer-Pietsch B, Simões ME, Barker C et al (2008) Effects of prior antiresorptive therapy on the bone mineral density response to two years of teriparatide treatment in postmenopausal women with osteoporosis. J Clin Endocrinol Metab 93:852–860
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 852-860
    • Boonen, S.1    Marin, F.2    Obermayer-Pietsch, B.3    Simões, M.E.4    Barker, C.5
  • 19
    • 70349897684 scopus 로고    scopus 로고
    • Effects of teriparatide in postmenopausal women with osteoporosis on prior alendronate or raloxifene: differences between stopping and continuing the antiresorptive agent
    • COI: 1:CAS:528:DC%2BD1MXht12ru7jO, PID: 19584192
    • Cosman F, Wermers RA, Recknor C, Mauck KF, Xie L et al (2009) Effects of teriparatide in postmenopausal women with osteoporosis on prior alendronate or raloxifene: differences between stopping and continuing the antiresorptive agent. J Clin Endocrinol Metab 94:3772–3780
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 3772-3780
    • Cosman, F.1    Wermers, R.A.2    Recknor, C.3    Mauck, K.F.4    Xie, L.5
  • 20
    • 78049522060 scopus 로고    scopus 로고
    • Odanacatib in the treatment of postmenopausal women with low bone mineral density: three-year continued therapy and resolution of effect
    • COI: 1:CAS:528:DC%2BC3MXjt1Wru7g%3D, PID: 20740685
    • Eisman JA, Bone HG, Hosking DJ, McClung MR, Reid IR et al (2011) Odanacatib in the treatment of postmenopausal women with low bone mineral density: three-year continued therapy and resolution of effect. J Bone Miner Res 26:242–251
    • (2011) J Bone Miner Res , vol.26 , pp. 242-251
    • Eisman, J.A.1    Bone, H.G.2    Hosking, D.J.3    McClung, M.R.4    Reid, I.R.5
  • 21
    • 79952698455 scopus 로고    scopus 로고
    • Denosumab and bisphosphonates: different mechanisms of action and effects
    • COI: 1:CAS:528:DC%2BC3MXjs12jtb4%3D, PID: 21145999
    • Baron R, Ferrari S, Russell RG (2011) Denosumab and bisphosphonates: different mechanisms of action and effects. Bone 48:677–692
    • (2011) Bone , vol.48 , pp. 677-692
    • Baron, R.1    Ferrari, S.2    Russell, R.G.3
  • 22
    • 69049083492 scopus 로고    scopus 로고
    • Denosumab for prevention of fractures in postmenopausal women with osteoporosis
    • COI: 1:CAS:528:DC%2BD1MXhtVWls7nF, PID: 19671655
    • Cummings SR, San Martin J, McClung MR, Siris ES, Eastell R et al (2009) Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med 361:756–765
    • (2009) N Engl J Med , vol.361 , pp. 756-765
    • Cummings, S.R.1    San Martin, J.2    McClung, M.R.3    Siris, E.S.4    Eastell, R.5
  • 23
    • 0004851872 scopus 로고    scopus 로고
    • Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture intervention trial research group
    • COI: 1:CAS:528:DyaK2sXisFCktQ%3D%3D, PID: 8950879
    • Black DM, Cummings SR, Karpf DB, Cauley JA, Thompson DE et al (1996) Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture intervention trial research group. Lancet 348:1535–1541
    • (1996) Lancet , vol.348 , pp. 1535-1541
    • Black, D.M.1    Cummings, S.R.2    Karpf, D.B.3    Cauley, J.A.4    Thompson, D.E.5
  • 24
    • 0033552255 scopus 로고    scopus 로고
    • Effects of risedronate treatment on vertebral and non vertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial
    • COI: 1:CAS:528:DyaK1MXmvFansr0%3D, PID: 10527181
    • Harris ST, Watts NB, Genant HK, McKeever CD, Hangartner T et al (1999) Effects of risedronate treatment on vertebral and non vertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. JAMA 282:1344–1352
    • (1999) JAMA , vol.282 , pp. 1344-1352
    • Harris, S.T.1    Watts, N.B.2    Genant, H.K.3    McKeever, C.D.4    Hangartner, T.5
  • 25
    • 84863620654 scopus 로고    scopus 로고
    • Efficacy of monthly oral ibandronate is sustained over 5 years: the MOBILE long-term extension study
    • COI: 1:CAS:528:DC%2BC38Xnt12msL8%3D, PID: 21953471
    • Miller PD, Recker RR, Reginster JY, Riis BJ, Czerwinski E et al (2012) Efficacy of monthly oral ibandronate is sustained over 5 years: the MOBILE long-term extension study. Osteoporos Int 23:1747–1756
    • (2012) Osteoporos Int , vol.23 , pp. 1747-1756
    • Miller, P.D.1    Recker, R.R.2    Reginster, J.Y.3    Riis, B.J.4    Czerwinski, E.5


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