Fraction of exhaled nitric oxide measurements and asthma control: Are the numbers starting to add up?

Journal of Allergy and Clinical Immunology

Volumn 135, Issue 3, 2015, Pages 689-690.e1

  Fleming, Louise ^a,b   Bush, Andrew ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b ROYAL BROMPTON AND HAREFIELD NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

asthma control; Asthma management; exhaled nitric oxide

Indexed keywords

CORTICOSTEROID; NITRIC OXIDE; ANTIASTHMATIC AGENT;

ASTHMA; CLINICAL DECISION MAKING; CLINICAL PRACTICE; CORTICOSTEROID THERAPY; COST EFFECTIVENESS ANALYSIS; EDITORIAL; EXHALATION; FORCED EXPIRATORY VOLUME; HUMAN; LUNG FUNCTION; PRIORITY JOURNAL; QUALITY ADJUSTED LIFE YEAR; ECONOMICS; FEMALE; MALE; METABOLISM;

ADRENAL CORTEX HORMONES; ANTI-ASTHMATIC AGENTS; ASTHMA; FEMALE; HUMANS; MALE; NITRIC OXIDE;

EID: 84924363129     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.12.1920     Document Type: Editorial

References (18)

1. Global Initiative for Asthma Global strategy for asthma management and prevention Available at: www.ginasthma.org 2014 Accessed October 2014
2. National Heart, Lung and Blood Institute. National Asthma Education and Prevention Program Expert Panel Report 3: guidelines for the diagnosis and management of asthma Available at: www.nhlbi.nih.gov/guidelines/asthma/asthgdln.htm 2007 Accessed July 2009
3. British Thoracic Society, Scottish Intercollegiate Guidelines Network British guideline on the management of asthma Thorax 69 suppl 1 2014 1 192
4. M.R. Partridge, T. van der Molen, S.E. Myrseth, and W.W. Busse Attitudes and actions of asthma patients on regular maintenance therapy: the INSPIRE study BMC Pulm Med 6 2006 13
5. E.D. Bateman, H.A. Boushey, J. Bousquet, W.W. Busse, T.J. Clark, and R.A. Pauwels Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma ControL study Am J Respir Crit Care Med 170 2004 836 844
6. P.J. Honkoop, R.J.B. Loijmans, E.H. Termeer, J.B. Snoeck-Stroband, W.B. van den Hout, and M.J. Bakker Symptom- and fraction of exhaled nitric oxide-driven strategies for asthma control: a cluster-randomized trial in primary care J Allergy Clin Immunol 135 2015 682 688
7. H.L. Petsky, C.J. Cates, T.J. Lasserson, A.M. Li, C. Turner, and J.A. Kynaston A systematic review and meta-analysis: tailoring asthma treatment on eosinophilic markers (exhaled nitric oxide or sputum eosinophils) Thorax 67 2012 199 208
8. H.L. Petsky, A.M. Li, C.T. Au, J.A. Kynaston, C. Turner, and A.B. Chang Management based on exhaled nitric oxide levels adjusted for atopy reduces asthma exacerbations in children: a dual centre randomized controlled trial Pediatr Pulmonol 2014 [Epub ahead of print]. doi:10.1002/ppul.23064
9. H. Powell, V.E. Murphy, D.R. Taylor, M.J. Hensley, K. McCaffery, and W. Giles Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: a double-blind, randomised controlled trial Lancet 378 2011 983 990
10. J. Syk, A. Malinovschi, G. Johansson, A.L. Unden, A. Andreasson, and M. Lekander Anti-inflammatory treatment of atopic asthma guided by exhaled nitric oxide: a randomized, controlled trial J Allergy Clin Immunol Pract 1 2013 639 648
11. Royal College of Physicians. Why asthma still kills: the national review of asthma deaths. Available at: https://www.rcplondon.ac.uk/sites/default/files/why-asthma-still-kills-full-report.pdf. Accessed October 31, 2014.
12. W.J. Calhoun, B.T. Ameredes, T.S. King, N. Icitovic, E.R. Bleecker, and M. Castro Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: the BASALT randomized controlled trial JAMA 308 2012 987 997
13. J.C. De Jongste, S. Carraro, W.C. Hop, and E. Baraldi Daily telemonitoring of exhaled nitric oxide and symptoms in the treatment of childhood asthma Am J Respir Crit Care Med 179 2009 93 97
14. M. Fritsch, S. Uxa, F. Horak Jr., B. Putschoegl, E. Dehlink, and Z. Szepfalusi Exhaled nitric oxide in the management of childhood asthma: a prospective 6-months study Pediatr Pulmonol 41 2006 855 862
15. M.W. Pijnenburg, E.M. Bakker, W.C. Hop, and J.C. De Jongste Titrating steroids on exhaled nitric oxide in children with asthma: a randomized controlled trial Am J Respir Crit Care Med 172 2005 831 836
16. D.E. Shaw, M.A. Berry, M. Thomas, R.H. Green, C.E. Brightling, and A.J. Wardlaw The use of exhaled nitric oxide to guide asthma management: a randomized controlled trial Am J Respir Crit Care Med 176 2007 231 237
17. A.D. Smith, J.O. Cowan, K.P. Brassett, G.P. Herbison, and D.R. Taylor Use of exhaled nitric oxide measurements to guide treatment in chronic asthma N Engl J Med 352 2005 2163 2173
18. S.J. Szefler, H. Mitchell, C.A. Sorkness, P.J. Gergen, G.T. O'Connor, and W.J. Morgan Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: a randomised controlled trial Lancet 372 2008 1065 1072