Visceral adiposity index and insulin secretion and action in first-degree relatives of subjects with type 2 diabetes

Diabetes/Metabolism Research and Reviews

Volumn 31, Issue 3, 2015, Pages 315-321

  Yang, Yumei ^a,b   Feng, Yan ^c   Ma, Xuesong ^d   Chen, Kaiting ^c   Wu, Nannan ^c   Wang, Dongmei ^d   Li, Pengjie ^a   Wang, Minnan ^a   Li, Qiang ^a   Zhang, Jinchao ^a  

^a Second Affiliated Hospital of Harbin Mecical University   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c HARBIN MEDICAL UNIVERSITY   (China)

^d Second Hospital of Mudanjiang City   (China)

Author keywords

First degree relatives; Insulin; Resistance; Type 2 diabetes; Visceral adiposity index; cell function

Indexed keywords

HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL; GLUCOSE BLOOD LEVEL; INSULIN;

ADULT; ARTICLE; CELL FUNCTION; FEMALE; FIRST DEGREE RELATIVE; GLUCOSE METABOLISM; HUMAN; HYPERGLYCEMIA; IMPAIRED GLUCOSE TOLERANCE; INSULIN RELEASE; LIPID STORAGE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; WAIST CIRCUMFERENCE; ABDOMINAL OBESITY; AGED; ANALYSIS; CROSS-SECTIONAL STUDY; FAMILY; FOLLOW UP; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; MIDDLE AGED; PATHOPHYSIOLOGY; PROGNOSIS; SECRETION (PROCESS); YOUNG ADULT;

ADIPOSITY; ADULT; AGED; BLOOD GLUCOSE; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; FAMILY; FEMALE; FOLLOW-UP STUDIES; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; MALE; MIDDLE AGED; OBESITY, ABDOMINAL; PREDIABETIC STATE; PROGNOSIS; YOUNG ADULT;

EID: 84924337105     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.2615     Document Type: Article

References (34)

1. WHO. Diabetes Mellitus Fact Sheet. Geneva:WHO., 2002; 138.
2. Bozorgmanesh MR, Hadaegh F, Padyab M, Mehrabi Y, Azizi F. Temporal changes in anthropometric parameters and lipid profile according to body mass index among an adult Iranian urban population. Ann Nutr Metab 2008; 53: 13-22.
3. Pontiroli AE, Monti LD, Costa S, et al. In middle-aged siblings of patients with type 2 diabetes mellitus normal glucose tolerance is associated with insulin resistance and with increased insulin secretion. The SPIDER study. Eur J Endocrinol 2000; 143: 681-686.
4. Jensen CC, Cnop M, Hull RL, Fujimoto WY, Kahn SE. Beta-cell function is a major contributor to oral glucose tolerance in high-risk relatives of four ethnic groups in the U.S. Diabetes 2002; 51: 2170-2178.
5. Fernandez-Castaner M, Biarnes J, Camps I, Ripolles J, Gomez N, Soler J. Beta-cell dysfunction in first-degree relatives of patients with non-insulin-dependent diabetes mellitus. Diabet Med 1996; 13: 953-959.
6. Humphriss DB, Stewart MW, Berrish TS, et al. Multiple metabolic abnormalities in normal glucose tolerant relatives of NIDDM families. Diabetologia 1997; 40: 1185-1190.
7. Despres JP. Intra-abdominal obesity: an untreated risk factor for Type 2 diabetes and cardiovascular disease. J Endocrinol Invest 2006; 29: 77-82.
8. Bruunsgaard H, Pedersen BK. Age-related inflammatory cytokines and disease. Immunol Allergy Clin North Am 2003; 23: 15-39.
9. DeNino WF, Tchernof A, Dionne IJ, et al. Contribution of abdominal adiposity to age-related differences in insulin sensitivity and plasma lipids in healthy nonobese women. Diabetes Care 2001; 24: 925-932.
10. Amato MC, Giordano C, Galia M, et al. Visceral Adiposity Index: a reliable indicator of visceral fat function associated with cardiometabolic risk. Diabetes Care 2010; 33: 920-922.
11. Elisha B, Messier V, Karelis A, et al. The Visceral Adiposity Index: Relationship with cardiometabolic risk factors in obese and overweight postmenopausal women - A MONET group study. Appl Physiol Nutr Metab 2013; 38: 892-899.
12. Amato MC, Giordano C, Pitrone M, Galluzzo A. Cut-off points of the visceral adiposity index (VAI) identifying a visceral adipose dysfunction associated with cardiometabolic risk in a Caucasian Sicilian population. Lipids Health Dis 2011; 10: 183.
13. Amato MC, Guarnotta V, Giordano C. Body composition assessment for the definition of cardiometabolic risk. J Endocrinol Invest 2013; 36: 537-543.
14. Zhang X, Shu XO, Li H, et al. Visceral adiposity and risk of coronary heart disease in relatively lean Chinese adults. Int J Cardiol 2013; 168: 2141-2145.
15. Kushner RF, Roth JL. Assessment of the obese patient. Endocrinol Metab Clin North Am 2003; 32: 915-933.
16. Pemmtt MA. Genetics of NIDDM. Diabetes Care 1990; 13: 1150.
17. Pan XR, Yang WY, Li GW, Liu J. Prevalence of diabetes and its risk factors in China, 1994. National Diabetes Prevention and Control Cooperative Group. Diabetes Care 1997; 20: 1664-1669.
18. Abdul-Ghani MA, Jenkinson CP, Richardson DK, Tripathy D, DeFronzo RA. Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose tolerance: results from the Veterans Administration Genetic Epidemiology Study. Diabetes 2006; 55: 1430-1435.
19. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-419.
20. Phillips DI, Clark PM, Hales CN, Osmond C. Understanding oral glucose tolerance: comparison of glucose or insulin measurements during the oral glucose tolerance test with specific measurements of insulin resistance and insulin secretion. Diabet Med 1994; 11: 286-292.
21. Bergman RN, Phillips LS, Cobelli C. Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose. J Clin Invest 1981; 68: 1456-1467.
22. Ryder E, Gomez ME, Fernandez V, et al. Presence of impaired insulin secretion and insulin resistance in normoglycemic male subjects with family history of type 2 diabetes. Diabetes Res Clin Pract 2003; 60: 95-103.
23. Kahn HS. The lipid accumulation product performs better than the body mass index for recognizing cardiovascular risk: a population-based comparison. BMC Cardiovasc Disord 2005; 5: 26.
24. Al-Daghri NM, Al-Attas OS, Alokail MS, et al. Visceral adiposity index is highly associated with adiponectin values and glycaemic disturbances. Eur J Clin Invest 2013; 43: 183-189.
25. Al-Daghri NM, Al-Attas OS, Alokail M, et al. Does visceral adiposity index signify early metabolic risk in children and adolescents?: Association with insulin resistance, adipokines, and subclinical inflammation. Pediatr Res 2014; 75: 459-463.
26. Oh JY, Sung YA, Lee HJ. The visceral adiposity index as a predictor of insulin resistance in young women with polycystic ovary syndrome. Obesity (Silver Spring) 2013; 21: 1690-1694.
27. Stepien M, Stepien A, Wlazel RN, et al. Predictors of insulin resistance in patients with obesity: a pilot study. Angiology 2014; 65: 22-30.
28. Ciresi A, Amato MC, Pizzolanti G, Giordano Galluzzo C. Visceral adiposity index is associated with insulin sensitivity and adipocytokine levels in newly diagnosed acromegalic patients. J Clin Endocrinol Metab 2012; 97: 2907-2915.
29. Wajchenberg BL. beta-cell failure in diabetes and preservation by clinical treatment. Endocr Rev 2007; 28: 187-218.
30. Cnop M. Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes. Biochem Soc Trans 2008; 36: 348-352.
31. Bedogni G, Kahn HS, Bellentani S, Tiribelli C. A simple index of lipid overaccumulation is a good marker of liver steatosis. BMC Gastroenterol 2010; 10: 98.
32. Szendroedi J, Roden M. Ectopic lipids and organ function. Curr Opin Lipidol 2009; 20: 50-56.
33. Bozorgmanesh M, Hadaegh F, Azizi F. Predictive performance of the visceral adiposity index for a visceral adiposity-related risk: type 2 diabetes. Lipids Health Dis 2011; 10: 88.
34. Du T, Sun X, Huo R, Yu X. Visceral adiposity index, hypertriglyceridemic waist and risk of diabetes: the China Health and Nutrition Survey 2009. Int J Obes (Lond) 2014; 38: 840-847.