Butyrfentanyl overdose resulting in diffuse alveolar hemorrhage

Pediatrics

Volumn 135, Issue 3, 2015, Pages e740-e743

  Cole, Jon B ^a   Dunbar, John F ^b   McIntire, Sarah A ^c   Regelmann, Warren E ^c   Slusher, Tina M ^d  

^a Hennepin Regional Poison Center   (United States)

^b HENNEPIN COUNTY MEDICAL CENTER   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d Division of Critical Care   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRFENTANYL; FENTANYL DERIVATIVE; NALOXONE; OPIATE DERIVATIVE; UNCLASSIFIED DRUG; FENTANYL; NARCOTIC ANALGESIC AGENT;

ACUTE LUNG INJURY; ADULT; ARTICLE; BREATHING DISORDER; BRONCHOSCOPY; CASE REPORT; DRUG OVERDOSE; DYSPNEA; ECHOCARDIOGRAPHY; EMERGENCY WARD; FALSE POSITIVE RESULT; GAS CHROMATOGRAPHY; HEART EJECTION FRACTION; HEMOPTYSIS; HEROIN DEPENDENCE; HUMAN; IMMUNOASSAY; INTRAVENOUS DRUG ABUSE; INTUBATION; LABORATORY TEST; LENGTH OF STAY; LUNG HEMORRHAGE; LUNG LAVAGE; MALE; MASS SPECTROMETRY; PHYSICAL EXAMINATION; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RESPIRATORY FAILURE; THORAX RADIOGRAPHY; UNCONSCIOUSNESS; VENTILATOR ASSOCIATED PNEUMONIA; VITAL SIGN; YOUNG ADULT; ANALOGS AND DERIVATIVES; COMPLICATION; DIFFERENTIAL DIAGNOSIS; LUNG ALVEOLUS; VASCULARIZATION;

ANALGESICS, OPIOID; BRONCHOSCOPY; DIAGNOSIS, DIFFERENTIAL; DRUG OVERDOSE; FENTANYL; HEMOPTYSIS; HUMANS; MALE; PULMONARY ALVEOLI; RADIOGRAPHY, THORACIC; YOUNG ADULT;

EID: 84924326319     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2014-2878     Document Type: Article

References (13)

1. Kuehn BM. Poisonings top crashes for injury-related deaths. JAMA. 2012;307(3):242
2. Centers for Disease Control and Prevention (CDC). Vital signs: overdoses of prescription opioid pain relievers - United States, 1999-2008. MMWR Morb Mortal Wkly Rep. 2011;60(43):1487-1492
3. Centers for Disease Control and Prevention (CDC). Acetyl fentanyl overdose fatalities - Rhode Island, March-May 2013. MMWR Morb Mortal Wkly Rep. 2013;62(34):703-704
4. Higashikawa Y, Suzuki S. Studies on 1-(2-phenethyl)-4-(N-propionylanilino) piperidine (fentanyl) and its related compounds. VI. Structure-analgesic activity relationship for fentanyl, methylsubstituted fentanyls and other analogues. Forensic Toxicol. 1998;26(1):1-5
5. Duberstein JL, Kaufman DM. A clinical study of an epidemic of heroin intoxication and heroin-induced pulmonary edema. Am J Med. 1971;51(6): 704-714
6. Porter R, O'Reilly H. Pulmonary hemorrhage: a rare complication of opioid overdose. Pediatr Emerg Care. 2011;27(8):742-744
7. Mills CA, Flacke JW, Miller JD, Davis LJ, Bloor BC, Flacke WE. Cardiovascular effects of fentanyl reversal by naloxone at varying arterial carbon dioxide tensions in dogs. Anesth Analg. 1988; 67(8):730-736
8. Mills CA, Flacke JW, Flacke WE, Bloor BC, Liu MD. Narcotic reversal in hypercapnic dogs: comparison of naloxone and nalbuphine. Can J Anaesth. 1990;37(2):238-244
9. Prough DS, Roy R, Bumgarner J, Shannon G. Acute pulmonary edema in healthy teenagers following conservative doses of intravenous naloxone. Anesthesiology. 1984;60(5): 485-486
10. Osler W. Oedema of the left lung-Morphia poisoning. Montreal Gen Hosp Rep. 1880; 1:291-293
11. Schwartz DR, Maroo A, Malhotra A, Kesselman H. Negative pressure pulmonary hemorrhage. Chest. 1999; 115(4):1194-1197
12. Alburges ME, Hanson GR, Gibb JW, Sakashita CO, Rollins DE. Fentanyl receptor assay. II. Utilization of a radioreceptor assay for the analysis of fentanyl analogs in urine. J Anal Toxicol. 1992;16(1):36-41
13. Ruangyuttikarn W, Law MY, Rollins DE, Moody DE. Detection of fentanyl and its analogs by enzyme-linked immunosorbent assay. J Anal Toxicol. 1990;14(3):160-164