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Volumn 29, Issue 1, 2015, Pages 70-74

Why are spousal caregivers more prevalent than nonspousal caregivers as study partners in AD dementia clinical trials?

Author keywords

Alzheimer disease; caregiver; clinical trial recruitment; research attitudes; research ethics

Indexed keywords

ADULT; AGE; AGED; ALZHEIMER DISEASE; ARTICLE; ATTITUDE; CAREGIVER; CAREGIVER BURDEN; DOMESTIC PARTNERSHIP; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PREVALENCE; PRIORITY JOURNAL; QUESTIONNAIRE; RESEARCH ATTITUDES QUESTIONNAIRE; RESEARCH ETHICS; SPOUSE; ATTITUDE TO HEALTH; CONTROLLED STUDY; MIDDLE AGED; PATIENT PARTICIPATION; PSYCHOLOGY; RANDOMIZED CONTROLLED TRIAL; TRENDS; VERY ELDERLY;

EID: 84924279007     PISSN: 08930341     EISSN: None     Source Type: Journal    
DOI: 10.1097/WAD.0000000000000047     Document Type: Article
Times cited : (37)

References (22)
  • 1
    • 78650728457 scopus 로고    scopus 로고
    • Addressing the challenges to successful recruitment and retention in Alzheimer's disease clinical trials
    • Grill JD, Karlawish J. Addressing the challenges to successful recruitment and retention in Alzheimer's disease clinical trials. Alz Res Ther. 2010;2:34.
    • (2010) Alz Res Ther , vol.2 , pp. 34
    • Grill, J.D.1    Karlawish, J.2
  • 2
    • 0035500741 scopus 로고    scopus 로고
    • Effect of early patient enrollment on the time to completion and publication of randomized controlled trials
    • Haidich AB, Ioannidis JP. Effect of early patient enrollment on the time to completion and publication of randomized controlled trials. Am J Epidemiol. 2001;154:873-880.
    • (2001) Am J Epidemiol , vol.154 , pp. 873-880
    • Haidich, A.B.1    Ioannidis, J.P.2
  • 3
    • 0037125417 scopus 로고    scopus 로고
    • The continuing unethical conduct of underpowered clinical trials
    • Halpern SD, Karlawish JH, Berlin JA. The continuing unethical conduct of underpowered clinical trials. JAMA. 2002;288:358-362.
    • (2002) JAMA , vol.288 , pp. 358-362
    • Halpern, S.D.1    Karlawish, J.H.2    Berlin, J.A.3
  • 4
    • 0035957250 scopus 로고    scopus 로고
    • How do AD patients and their caregivers decide whether to enroll in a clinical trial?
    • Karlawish JHT, Casarett D, Klocinksi J, et al. How do AD patients and their caregivers decide whether to enroll in a clinical trial? Neurology. 2001;56:789-792.
    • (2001) Neurology , vol.56 , pp. 789-792
    • Karlawish, J.H.T.1    Casarett, D.2    Klocinksi, J.3
  • 5
    • 0036901261 scopus 로고    scopus 로고
    • Alzheimer's disease patients' and caregivers' capacity, competency, and reasons to enroll in an early-phase Alzheimer's disease clinical trial
    • Karlawish JH, Casarett DJ, James BD. Alzheimer's disease patients' and caregivers' capacity, competency, and reasons to enroll in an early-phase Alzheimer's disease clinical trial. J Am Geriatr Soc. 2002;50:2019-2024.
    • (2002) J Am Geriatr Soc , vol.50 , pp. 2019-2024
    • Karlawish, J.H.1    Casarett, D.J.2    James, B.D.3
  • 6
    • 33744900086 scopus 로고    scopus 로고
    • Optimal design of clinical trials for drugs designed to slow the course of Alzheimer's disease
    • Mohs RC, Kawas C, Carrillo MC. Optimal design of clinical trials for drugs designed to slow the course of Alzheimer's disease. Alzheimers Dement. 2006;2:131-139.
    • (2006) Alzheimers Dement , vol.2 , pp. 131-139
    • Mohs, R.C.1    Kawas, C.2    Carrillo, M.C.3
  • 7
    • 84858225391 scopus 로고    scopus 로고
    • 2012 Alzheimer's disease facts and figures
    • Alzheimer's Association
    • Alzheimer's Association. 2012 Alzheimer's disease facts and figures. Alzheimers Dement. 2012;8:131-168.
    • (2012) Alzheimers Dement , vol.8 , pp. 131-168
  • 8
    • 29744461778 scopus 로고    scopus 로고
    • Alzheimer's Association and National Alliance for Caregiving Available at Accessed May 29, 2009
    • Alzheimer's Association and National Alliance for Caregiving. Families care: Alzheimer's caregiving in the United States. 2004. Available at: http://www.alz.org/national/documents/report-familiescare.pdf. Accessed May 29, 2009.
    • (2004) Families Care: Alzheimer's Caregiving in the United States
  • 9
    • 84873670904 scopus 로고    scopus 로고
    • Effect of study partner on the conduct of Alzheimer disease clinical trials
    • Grill JD, Raman R, Ernstrom K, et al. Effect of study partner on the conduct of Alzheimer disease clinical trials. Neurology. 2013;80:282-288.
    • (2013) Neurology , vol.80 , pp. 282-288
    • Grill, J.D.1    Raman, R.2    Ernstrom, K.3
  • 10
    • 60349125615 scopus 로고    scopus 로고
    • Older adults' attitudes toward noncompetent subjects participating in Alzheimer's research
    • Karlawish J, Rubright J, Casarett D, et al. Older adults' attitudes toward noncompetent subjects participating in Alzheimer's research. Am J Psychiatry. 2009;166:182-188.
    • (2009) Am J Psychiatry , vol.166 , pp. 182-188
    • Karlawish, J.1    Rubright, J.2    Casarett, D.3
  • 11
    • 60549105569 scopus 로고    scopus 로고
    • Surrogate consent for dementia research: A national survey of older Americans
    • Kim SYH, Kim HM, Langa KM, et al. Surrogate consent for dementia research: a national survey of older Americans. Neurology. 2009;72:149-155.
    • (2009) Neurology , vol.72 , pp. 149-155
    • Kim, S.Y.H.1    Kim, H.M.2    Langa, K.M.3
  • 12
    • 79951891312 scopus 로고    scopus 로고
    • Clinical research participation among aging adults enrolled in an Alzheimer's Disease Center research registry
    • Jefferson AL, Lambe S, Chaisson C, et al. Clinical research participation among aging adults enrolled in an Alzheimer's Disease Center research registry. J Alzheimers Dis. 2011; 23:443-452.
    • (2011) J Alzheimers Dis , vol.23 , pp. 443-452
    • Jefferson, A.L.1    Lambe, S.2    Chaisson, C.3
  • 13
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease. Report of the NINCDSADRDA work group under auspices of the Department of Health and Human Services Task Force on Alzheimer's disease
    • McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease. Report of the NINCDSADRDA work group under auspices of the Department of Health and Human Services Task Force on Alzheimer's disease. Neurology. 1984;34:939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3
  • 14
    • 62849097580 scopus 로고    scopus 로고
    • How redesigning AD clinical trials might increase study partners' willingness to participate
    • Karlawish J, Cary MS, Rubright J, et al. How redesigning AD clinical trials might increase study partners' willingness to participate. Neurology. 2008;71:1883-1888.
    • (2008) Neurology , vol.71 , pp. 1883-1888
    • Karlawish, J.1    Cary, M.S.2    Rubright, J.3
  • 15
    • 1642572165 scopus 로고
    • Studies of illness in the aged. The Index of ADL: A standardized measure of biological and psychosocial function
    • Katz S, Ford AB, Moskowitz RW, et al. Studies of illness in the aged. The Index of ADL: a standardized measure of biological and psychosocial function. JAMA. 1963;185: 914-919.
    • (1963) JAMA , vol.185 , pp. 914-919
    • Katz, S.1    Ford, A.B.2    Moskowitz, R.W.3
  • 16
    • 0014579432 scopus 로고
    • Assessment of older people: Selfmaintaining and instrumental activities of daily living
    • Lawton MP, Brody EM. Assessment of older people: Selfmaintaining and instrumental activities of daily living. Gerontologist. 1969;9:179-186.
    • (1969) Gerontologist , vol.9 , pp. 179-186
    • Lawton, M.P.1    Brody, E.M.2
  • 17
    • 0034028609 scopus 로고    scopus 로고
    • Validation of the NPI-Q, a brief clinical form of the Neuropsychiatric Inventory
    • Kaufer DI, Cummings JL, Ketchel P, et al. Validation of the NPI-Q, a brief clinical form of the Neuropsychiatric Inventory. J Neuropsychiatry Clin Neurosci. 2000;12:233-239.
    • (2000) J Neuropsychiatry Clin Neurosci , vol.12 , pp. 233-239
    • Kaufer, D.I.1    Cummings, J.L.2    Ketchel, P.3
  • 18
    • 0022826675 scopus 로고
    • Geriatric Depression Scale (GDS): Recent evidence and development of a shorter version
    • Brink TL, ed. New York, NY: The Haworth Press
    • Sheikh JI, Yesavage JA. Geriatric Depression Scale (GDS): recent evidence and development of a shorter version. In: Brink TL, ed. Clinical Gerontology: A Guide to Assessment and Intervention. New York, NY: The Haworth Press; 1986:165-173.
    • (1986) Clinical Gerontology: A Guide to Assessment and Intervention , pp. 165-173
    • Sheikh, J.I.1    Yesavage, J.A.2
  • 19
    • 6944222854 scopus 로고    scopus 로고
    • The development of a rapid screen for caregiver burden
    • Hirschman KB, Shea J, Xie SX, et al. The development of a rapid screen for caregiver burden. J Am Geriatr Soc. 2004;52: 1724-1729.
    • (2004) J Am Geriatr Soc , vol.52 , pp. 1724-1729
    • Hirschman, K.B.1    Shea, J.2    Xie, S.X.3
  • 20
    • 84924264218 scopus 로고    scopus 로고
    • Erratum
    • Erratum in: J Am Geriatr Soc. 2005;1753:1556.
    • (2005) J Am Geriatr Soc. , vol.1753 , pp. 1556
  • 21
    • 79954512388 scopus 로고    scopus 로고
    • Measuring how people view biomedical research: Reliability and validity analysis of the Research Attitudes Questionnaire
    • Rubright JD, Cary MS, Karlawish JH, et al. Measuring how people view biomedical research: reliability and validity analysis of the Research Attitudes Questionnaire. J Empir Res Hum Res Ethics. 2011;6:63-68.
    • (2011) J Empir Res Hum Res Ethics , vol.6 , pp. 63-68
    • Rubright, J.D.1    Cary, M.S.2    Karlawish, J.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.