Propofol, midazolam, vancomycin and cyclosporine therapeutic drug monitoring in extracorporeal membrane oxygenation circuits primed with whole human blood

Critical Care

Volumn 19, Issue 1, 2015, Pages

  Lemaitre, Florian ^a,b,c,d   Hasni, Nesrine ^a   Leprince, Pascal ^f,g   Corvol, Emmanuel ^g   Belhabib, Ghassen ^a   Fillâtre, Pierre ^b,c,d   Luyt, Charles Edouard ^e,f   Leven, Cyril ^b,c,d   Farinotti, Robert ^a   Fernandez, Christine ^a,g   Combes, Alain ^e,f  

^a EA4123   (France)

^b RENNES UNIVERSITY HOSPITAL   (France)

^c UNIVERSITÉ DE RENNES 1   (France)

^d UNIVERSITÉ DE RENNES 1   (France)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^f SORBONNE UNIVERSITÉ   (France)

^g ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN; MIDAZOLAM; OXYGEN; POLYPROPYLENE; POLYVINYLCHLORIDE; PROPOFOL; VANCOMYCIN; ANTIINFECTIVE AGENT; HYPNOTIC SEDATIVE AGENT;

ARTICLE; BLOOD; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG MONITORING; EX VIVO STUDY; EXTRACORPOREAL OXYGENATION; HUMAN; PRIORITY JOURNAL; TEMPERATURE; BIOLOGICAL MODEL; CRITICAL ILLNESS; DEVICES;

ANTI-INFECTIVE AGENTS; BLOOD; CRITICAL ILLNESS; CYCLOSPORINE; DRUG MONITORING; EXTRACORPOREAL MEMBRANE OXYGENATION; HUMANS; HYPNOTICS AND SEDATIVES; MIDAZOLAM; MODELS, BIOLOGICAL; POLYVINYL CHLORIDE; PROPOFOL; VANCOMYCIN;

EID: 84924258306     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/s13054-015-0772-5     Document Type: Article

References (21)

1. Mulla H, Lawson G, von Anrep C, Burke MD, Upton DU, Firmin RK, et al. In vitro evaluation of sedative drug losses during extracorporeal membrane oxygenation. Perfusion. 2000;15:21-6.
2. Buck ML. Pharmacokinetic changes during extracorporeal membrane oxygenation: implications for drug therapy of neonates. Clin Pharmacokinet. 2003;42:403-17.
3. Dagan O, Klein J, Gruenwald C, Bohn D, Barker G, Koren G. Preliminary studies of the effects of extracorporeal membrane oxygenator on the disposition of common pediatric drugs. Ther Drug Monit. 1993;15:263-6.
4. Leprince P, Aubert S, Bonnet N, Rama A, Léger P, Bors V, et al. Peripheral extracorporeal membrane oxygenation (ECMO) in patients with posttransplant cardiac graft failure. Transplant Proc. 2005;37:2879-80.
5. Shekar K, Fraser JF, Smith MT, Roberts JA. Pharmacokinetic changes in patients receiving extracorporeal membrane oxygenation. J Crit Care. 2012;27(741):e9-18.
6. Wildschut ED, Ahsman MJ, Allegaert K, Mathot RAA, Tibboel D. Determinants of drug absorption in different ECMO circuits. Intensive Care Med. 2010;36:2109-16.
7. Lemaitre F, Luyt CE, Roullet-Renoleau F, Nieszkowska A, Zahr N, Corvol E, et al. Impact of extracorporeal membrane oxygenation and continuous venovenous hemodiafiltration on the pharmacokinetics of oseltamivir carboxylate in critically ill patients with pandemic (H1N1) influenza. Ther Drug Monit. 2012;34:171-5.
8. Lemaitre F, Luyt CE, Roullet-Renoleau F, Nieszkowska A, Zahr N, Fernandez C, et al. Oseltamivir carboxylate accumulation in a patient treated by haemodiafiltration and extracorporeal membrane oxygenation. Intensive Care Med. 2010;36:1273-4.
9. Spriet I, Annaert P, Meersseman P, Hermans G, Meersseman W, Verbesselt R, et al. Pharmacokinetics of caspofungin and voriconazole in critically ill patients during extracorporeal membrane oxygenation. J Antimicrob Chemother. 2009;63:767-70.
10. The R Project for Statistical Computing. http://www.r-project.org/ .
11. Shekar K, Roberts JA, Ghassabian S, Mullany DV, Ziegenfuss M, Smith MT, et al. Sedation during extracorporeal membrane oxygenation-why more is less. Anaesth Intensive Care. 2012;40:1067-9.
12. Shekar K, Roberts JA, Ghassabian S, Mullany DV, Wallis SC, Smith MT, et al. Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern? J Antimicrob Chemother. 2013;68:726-7.
13. Drug Bank: Propofol (DB00818). www.drugbank.ca/drugs/DB00818 . Accessed 1 Oct 2014.
14. Drug Bank: Midazolam (DB00683). www.drugbank.ca/drugs/DB00683 . Accessed 1 Oct 2014.
15. Drug Bank: Cyclosporine (DB00091). www.drugbank.ca/drugs/DB00091 . Accessed 1 Oct 2014.
16. Drug Bank: Vancomycin (DB00512). www.drugbank.ca/drugs/DB00512 . Accessed 1 Oct 2014.
17. Hynynen M, Hammarén E, Rosenberg PH. Propofol sequestration within the extracorporeal circuit. Can J Anaesth J Can Anesthésie. 1994;41:583-8.
18. Farinotti R. Physicochemical interactions and mode of storage of Diprivan. Ann Françaises Anesthèsie Rèanimation. 1994;13:453-6. French.
19. Shekar K, Roberts JA, McDonald CI, Fisquet S, Barnett AG, Mullany DV, et al. Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenation. Crit Care. 2012;16:R194.
20. Mehta NM, Halwick DR, Dodson BL, Thompson JE, Arnold JH. Potential drug sequestration during extracorporeal membrane oxygenation: results from an ex vivo experiment. Intensive Care Med. 2007;33:1018-24.
21. Shibata N, Ikuno Y, Tsubakimoto Y, Hoshino N, Minouchi T, Yoshio K, et al. Adsorption and pharmacokinetics of cyclosporin A in relation to mode of infusion in bone marrow transplant patients. Bone Marrow Transplant. 2000;25:633-8.