Simvastatin plus capecitabine-cisplatin versus placebo plus capecitabine-cisplatin in patients with previously untreated advanced gastric cancer: A double-blind randomised phase 3 study

European Journal of Cancer

Volumn 50, Issue 16, 2014, Pages 2822-2830

  Kim, Seung Tae ^a   Kang, Jung Hun ^b   Lee, Jeeyun ^a   Park, Se Hoon ^a   Park, Joon Oh ^a   Park, Young Suk ^a   Lim, Ho Yeong ^a   Hwang, In Gyu ^c   Lee, Sang Cheol ^d   Park, Keon Woo ^e   Lee, Hyo Rak ^f   Kang, Won Ki ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Gyeongsang National University   (South Korea)

^c Chung Ang University   (South Korea)

^d Soonchunhyang University   (South Korea)

^e Dankook University   (South Korea)

^f Korea Cancer Center Hospital   (South Korea)

Author keywords

A (HMG CoA); Gastric cancer; Simvastatin; Synthetic 3 hydroxy 3 methyglutaryl coenzyme

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CAPECITABINE; CISPLATIN; CREATINE KINASE; PLACEBO; SIMVASTATIN; 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A; ACYL COENZYME A; ANTINEOPLASTIC AGENT; DEOXYCYTIDINE; FLUOROURACIL;

ADULT; ADVANCED CANCER; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANEMIA; ANOREXIA; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CANCER COMBINATION CHEMOTHERAPY; CANCER GROWTH; CANCER SURVIVAL; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DIARRHEA; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; FEBRILE NEUTROPENIA; FEMALE; HAND FOOT SYNDROME; HUMAN; HYPERTRANSAMINASEMIA; KOREA; MAJOR CLINICAL STUDY; MALE; MUCOSA INFLAMMATION; MULTICENTER STUDY; MULTIPLE CYCLE TREATMENT; NAUSEA; NEUROPATHY; NEUTROPENIA; OVERALL SURVIVAL; PAIN; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; STOMACH ADENOCARCINOMA; THROMBOCYTOPENIA; TREATMENT DURATION; TREATMENT OUTCOME; VOMITING; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CLINICAL TRIAL; DISEASE FREE SURVIVAL; MIDDLE AGED; PROSPECTIVE STUDY; STOMACH NEOPLASMS; YOUNG ADULT;

ACYL COENZYME A; ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CISPLATIN; DEOXYCYTIDINE; DISEASE-FREE SURVIVAL; DOUBLE-BLIND METHOD; FEMALE; FLUOROURACIL; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SIMVASTATIN; STOMACH NEOPLASMS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84924234737     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2014.08.005     Document Type: Article

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