Null mutation of the nicotinamide adenine dinucleotide phosphate-oxidase subunit p67phox protects the Dahl-S rat from salt-induced reductions in medullary blood flow and glomerular filtration rate

Hypertension

Volumn 65, Issue 3, 2015, Pages 561-568

  Evans, Louise C ^a   Ryan, Robert P ^a   Broadway, Elizabeth ^a   Skelton, Meredith M ^a   Kurth, Theresa ^a   Cowley, Allen W ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

hypertension; inbred Dahl rats; kidney; NADPH oxidase

Indexed keywords

CREATININE; FLUORESCEIN ISOTHIOCYANATE; GLASS FIBER; PROTEIN P67; PROTEIN P67 PHOX; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG; OXIDOREDUCTASE; P67PHOX PROTEIN, RAT; REACTIVE OXYGEN METABOLITE; SALT INTAKE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD FLOW; BLOOD PRESSURE; CONTROLLED STUDY; CREATININE CLEARANCE; CREATININE URINE LEVEL; DAHL SALT SENSITIVE RAT; GENE MUTATION; GLOMERULUS FILTRATION RATE; HISTOLOGY; HYPERTENSION; KIDNEY BLOOD FLOW; KIDNEY MEDULLA; KNOCKOUT RAT; LASER DOPPLER FLOWMETRY; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; NULL MUTATION; PRIORITY JOURNAL; PROTEIN URINE LEVEL; PROTEINURIA; RAT; SALT INTAKE; TELEMETRY; WILD TYPE RAT; ADVERSE EFFECTS; ANIMAL; DAHL RAT; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; GENETICS; METABOLISM; MUTANT RAT STRAIN; MUTATION; PATHOPHYSIOLOGY; PHARMACOLOGY; PHYSIOLOGY; VASCULARIZATION;

ANIMALS; BLOOD PRESSURE; CREATININE; DISEASE MODELS, ANIMAL; GLOMERULAR FILTRATION RATE; HYPERTENSION; KIDNEY MEDULLA; MALE; MUTATION; NADH, NADPH OXIDOREDUCTASES; PROTEINURIA; RATS; RATS, INBRED DAHL; RATS, MUTANT STRAINS; REACTIVE OXYGEN SPECIES; REGIONAL BLOOD FLOW; SODIUM CHLORIDE, DIETARY;

EID: 84924233263     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.114.04468     Document Type: Article

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