-
1
-
-
84866862867
-
Systemic juvenile idiopathic arthritis
-
Martini A: Systemic juvenile idiopathic arthritis. Autoimmun Rev 2012, 12:56-9. 10.1016/j.autrev.2012.07.022
-
(2012)
Autoimmun Rev
, vol.12
, pp. 56-59
-
-
Martini, A.1
-
2
-
-
84858658227
-
Systemic arthritis in children: a review of clinical presentation and treatment
-
Gurion R, Lehman TJ, Moorthy LN: Systemic arthritis in children: a review of clinical presentation and treatment. Int J Inflam 2012, 2012:271569.
-
(2012)
Int J Inflam
, vol.2012
-
-
Gurion, R.1
Lehman, T.J.2
Moorthy, L.N.3
-
3
-
-
84871321221
-
Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis
-
Ruperto N, Brunner HI, Quartier P, Constantin T, Wulffraat N, Horneff G, et al.: Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis. N Engl J Med 2012, 367:2396-406. 10.1056/NEJMoa1205099
-
(2012)
N Engl J Med
, vol.367
, pp. 2396-2406
-
-
Ruperto, N.1
Brunner, H.I.2
Quartier, P.3
Constantin, T.4
Wulffraat, N.5
Horneff, G.6
-
4
-
-
20144362101
-
Therapeutic efficacy of humanized recombinant anti-interleukin6receptor antibody in children with systemic-onset juvenile idiopathic arthritis
-
Yokota S, Miyamae T, Imagawa T, Iwata N, Katakura S, Mori M, et al.: Therapeutic efficacy of humanized recombinant anti-interleukin6receptor antibody in children with systemic-onset juvenile idiopathic arthritis. Arthritis Rheum 2005, 52:818-25. 10.1002/art.20944
-
(2005)
Arthritis Rheum
, vol.52
, pp. 818-825
-
-
Yokota, S.1
Miyamae, T.2
Imagawa, T.3
Iwata, N.4
Katakura, S.5
Mori, M.6
-
5
-
-
40749152243
-
Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomized, double-blind, placebo-controlled, withdrawal phase III trial
-
Yokota S, Imagawa T, Mori M, Miyamae T, Aihara Y, Takei S, et al.: Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomized, double-blind, placebo-controlled, withdrawal phase III trial. Lancet 2008, 371:998-1006. 10.1016/S0140-6736(08)60454-7
-
(2008)
Lancet
, vol.371
, pp. 998-1006
-
-
Yokota, S.1
Imagawa, T.2
Mori, M.3
Miyamae, T.4
Aihara, Y.5
Takei, S.6
-
6
-
-
84871318830
-
Randomized trial of tocilizumab in systemic juvenile idiopathic arthritis
-
De Benedetti F, Brunner HI, Ruperto N, Kenwright A, Wright S, Calvo I, et al.: Randomized trial of tocilizumab in systemic juvenile idiopathic arthritis. N Engl J Med 2012, 367:2385-95. 10.1056/NEJMoa1112802
-
(2012)
N Engl J Med
, vol.367
, pp. 2385-2395
-
-
De Benedetti, F.1
Brunner, H.I.2
Ruperto, N.3
Kenwright, A.4
Wright, S.5
Calvo, I.6
-
7
-
-
18644385243
-
Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1blockade
-
Pascual V, Allantaz F, Arce E, Punaro M, Banchereau J: Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1blockade. J Exp Med 2005, 201:1479-86. 10.1084/jem.20050473
-
(2005)
J Exp Med
, vol.201
, pp. 1479-1486
-
-
Pascual, V.1
Allantaz, F.2
Arce, E.3
Punaro, M.4
Banchereau, J.5
-
8
-
-
0026014522
-
Correlation of serum interleukin-6 with joint involvement and thrombocytosis in systemic juvenile rheumatoid arthritis
-
De Benedetti F, Massa M, Robbioni P, Ravelli A, Burgio GR, Martini A: Correlation of serum interleukin-6 with joint involvement and thrombocytosis in systemic juvenile rheumatoid arthritis. Arthritis Rheum 1991, 34:1158-63. 10.1002/art.1780340912
-
(1991)
Arthritis Rheum
, vol.34
, pp. 1158-1163
-
-
De Benedetti, F.1
Massa, M.2
Robbioni, P.3
Ravelli, A.4
Burgio, G.R.5
Martini, A.6
-
9
-
-
0028345082
-
Serum soluble interleukin 6 (IL-6) receptor and IL-6/soluble IL-6 receptor complex in systemic juvenile rheumatoid arthritis
-
De Benedetti F, Massa M, Pignatti P, Albani S, Novick D, Martini A: Serum soluble interleukin 6 (IL-6) receptor and IL-6/soluble IL-6 receptor complex in systemic juvenile rheumatoid arthritis. J Clin Invest 1994, 93:2114-9. 10.1172/JCI117206
-
(1994)
J Clin Invest
, vol.93
, pp. 2114-2119
-
-
De Benedetti, F.1
Massa, M.2
Pignatti, P.3
Albani, S.4
Novick, D.5
Martini, A.6
-
10
-
-
84875536558
-
Tocilizumab for systemic juvenile idiopathic arthritis
-
De Benedetti F: Tocilizumab for systemic juvenile idiopathic arthritis. N Engl J Med 2013, 368:1256-7.
-
(2013)
N Engl J Med
, vol.368
, pp. 1256-1257
-
-
De Benedetti, F.1
-
11
-
-
31544451391
-
Open label phase II trial of single, ascending doses of MRA in Caucasianchildren with severe systemic juvenile idiopathic arthritis: proof of principle of the efficacy of IL-6 receptor blockade in this type of arthritis and demonstration of prolonged clinical improvement
-
Woo P, Wilkinson N, Prieur AM, Southwood T, Leone V, Livermore P, et al.: Open label phase II trial of single, ascending doses of MRA in Caucasianchildren with severe systemic juvenile idiopathic arthritis: proof of principle of the efficacy of IL-6 receptor blockade in this type of arthritis and demonstration of prolonged clinical improvement. Arthritis Res Ther 2005, 7:R1281-8. 10.1186/ar1826
-
(2005)
Arthritis Res Ther
, vol.7
, pp. R1281-R1288
-
-
Woo, P.1
Wilkinson, N.2
Prieur, A.M.3
Southwood, T.4
Leone, V.5
Livermore, P.6
-
12
-
-
33749363027
-
Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate
-
Maini RN, Taylor PC, Szechinski J, Pavelka K, Bröll J, Balint G, et al.: Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate. Arthritis Rheum 2006, 54:2817-29. 10.1002/art.22033
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2817-2829
-
-
Maini, R.N.1
Taylor, P.C.2
Szechinski, J.3
Pavelka, K.4
Bröll, J.5
Balint, G.6
-
13
-
-
84924129278
-
Efficacy and Safety Of Tocilizumab In Patients With Polyarticular-Course Juvenile Idiopathic Arthritis: 2-YearData From Cherish
-
Brunner HI, Ruperto N, Zuber Z, Cuttica RJ, Xavier R, Calvo I, et al.: Efficacy and Safety Of Tocilizumab In Patients With Polyarticular-Course Juvenile Idiopathic Arthritis: 2-YearData From Cherish. Arthritis Rheum 2013, 65:S335.
-
(2013)
Arthritis Rheum
, vol.65
, pp. S335
-
-
Brunner, H.I.1
Ruperto, N.2
Zuber, Z.3
Cuttica, R.J.4
Xavier, R.5
Calvo, I.6
-
14
-
-
84861479447
-
Safety and efficacy of tocilizumab, an anti-IL-6-receptor monoclonal antibody, in patients with polyarticular-course juvenile idiopathic arthritis
-
Imagawa T, Yokota S, Mori M, Miyamae T, Takei S, Imanaka H, et al.: Safety and efficacy of tocilizumab, an anti-IL-6-receptor monoclonal antibody, in patients with polyarticular-course juvenile idiopathic arthritis. Mod Rheumatol 2012, 22:109-15. 10.3109/s10165-011-0481-0
-
(2012)
Mod Rheumatol
, vol.22
, pp. 109-115
-
-
Imagawa, T.1
Yokota, S.2
Mori, M.3
Miyamae, T.4
Takei, S.5
Imanaka, H.6
-
15
-
-
10744230484
-
International League ofAssociations for Rheumatology. International League of Associations for Rheumatologyclassification of juvenile idiopathic arthritis: second revision, Edmonton 2001
-
Petty RE, Southwood TR, Manners P, Baum J, Glass DN, Goldenberg J, et al.: International League ofAssociations for Rheumatology. International League of Associations for Rheumatologyclassification of juvenile idiopathic arthritis: second revision, Edmonton 2001. J Rheumatol 2004, 31:390-2.
-
(2004)
J Rheumatol
, vol.31
, pp. 390-392
-
-
Petty, R.E.1
Southwood, T.R.2
Manners, P.3
Baum, J.4
Glass, D.N.5
Goldenberg, J.6
-
16
-
-
0030960980
-
Preliminary definition of improvement in juvenile arthritis
-
Giannini EH, Ruperto N, Ravelli A, Lovell DJ, Felson DT, Martini A: Preliminary definition of improvement in juvenile arthritis. Arthritis Rheum 1997, 40:1202-9. 10.1002/1529-0131(199707)40:7<1202::AID-ART3>3.0.CO;2-R
-
(1997)
Arthritis Rheum
, vol.40
, pp. 1202-1209
-
-
Giannini, E.H.1
Ruperto, N.2
Ravelli, A.3
Lovell, D.J.4
Felson, D.T.5
Martini, A.6
-
17
-
-
0036707740
-
Macrophage activation syndrome
-
Ravelli A: Macrophage activation syndrome. Curr Opin Rheumatol 2002, 14:548-52. 10.1097/00002281-200209000-00012
-
(2002)
Curr Opin Rheumatol
, vol.14
, pp. 548-552
-
-
Ravelli, A.1
-
18
-
-
18144367693
-
Preliminary diagnostic guidelines for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis
-
Ravelli A, Magni-Manzoni S, Pistorio A, Besana C, Foti T, Ruperto N, et al.: Preliminary diagnostic guidelines for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis. J Pediatr 2005, 146:598-604. 10.1016/j.jpeds.2004.12.016
-
(2005)
J Pediatr
, vol.146
, pp. 598-604
-
-
Ravelli, A.1
Magni-Manzoni, S.2
Pistorio, A.3
Besana, C.4
Foti, T.5
Ruperto, N.6
-
19
-
-
7544222361
-
Preliminary criteria for clinical remission for select categories of juvenile idiopathic arthritis. Childhood Arthritis and Rheumatology Research Alliance; Pediatric Rheumatology International Trials Organization; Pediatric Rheumatology Collaborative Study Group
-
Wallace CA, Ruperto N, Giannini E: Preliminary criteria for clinical remission for select categories of juvenile idiopathic arthritis. Childhood Arthritis and Rheumatology Research Alliance; Pediatric Rheumatology International Trials Organization; Pediatric Rheumatology Collaborative Study Group. J Rheumatol 2004, 31:2290-4.
-
(2004)
J Rheumatol
, vol.31
, pp. 2290-2294
-
-
Wallace, C.A.1
Ruperto, N.2
Giannini, E.3
-
20
-
-
31544465967
-
Systemic juvenile idiopathic arthritis: diagnosis, management, and outcome
-
Woo P: Systemic juvenile idiopathic arthritis: diagnosis, management, and outcome. Nat ClinPract Rheumatol 2006, 2:28-34. 10.1038/ncprheum0084
-
(2006)
Nat ClinPract Rheumatol
, vol.2
, pp. 28-34
-
-
Woo, P.1
-
21
-
-
84863428204
-
Consensus treatment plans for new-onset systemic juvenile idiopathic arthritis. Juvenile Idiopathic Arthritis Disease-specific Research Committee of Childhood Arthritis Rheumatology and Research Alliance
-
DeWitt EM, Kimura Y, Beukelman T, Nigrovic PA, Onel K, Prahalad S, et al.: Consensus treatment plans for new-onset systemic juvenile idiopathic arthritis. Juvenile Idiopathic Arthritis Disease-specific Research Committee of Childhood Arthritis Rheumatology and Research Alliance. Arthritis Care Res (Hoboken) 2012, 64:1001-10.
-
(2012)
Arthritis Care Res (Hoboken)
, vol.64
, pp. 1001-1010
-
-
DeWitt, E.M.1
Kimura, Y.2
Beukelman, T.3
Nigrovic, P.A.4
Onel, K.5
Prahalad, S.6
-
22
-
-
43949116263
-
The pattern of response to anti-interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis
-
Gattorno M, Piccini A, Lasigliè D, Tassi S, Brisca G, Carta S, et al.: The pattern of response to anti-interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis. Arthritis Rheum 2008, 58:1505-15. 10.1002/art.23437
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1505-1515
-
-
Gattorno, M.1
Piccini, A.2
Lasigliè, D.3
Tassi, S.4
Brisca, G.5
Carta, S.6
-
23
-
-
0024459013
-
Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease
-
Yoshizaki K, Matsuda T, Nishimoto N, Kuritani T, Taeho L, Aozasa K, et al.: Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease. Blood 1989, 74:1360-7.
-
(1989)
Blood
, vol.74
, pp. 1360-1367
-
-
Yoshizaki, K.1
Matsuda, T.2
Nishimoto, N.3
Kuritani, T.4
Taeho, L.5
Aozasa, K.6
-
24
-
-
27144488346
-
Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease
-
Nishimoto N, Kanakura Y, Aozasa K, Johkoh T, Nakamura M, Nakano S, et al.: Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease. Blood 2005, 106:2627-32. 10.1182/blood-2004-12-4602
-
(2005)
Blood
, vol.106
, pp. 2627-2632
-
-
Nishimoto, N.1
Kanakura, Y.2
Aozasa, K.3
Johkoh, T.4
Nakamura, M.5
Nakano, S.6
-
25
-
-
0030755904
-
Differences in synovial fluid cytokine levels between juvenile and adult rheumatoid arthritis
-
De Benedetti F, Pignatti P, Gerloni V, Massa M, Sartirana P, Caporali R, et al.: Differences in synovial fluid cytokine levels between juvenile and adult rheumatoid arthritis. J Rheumatol 1997, 24:1403-9.
-
(1997)
J Rheumatol
, vol.24
, pp. 1403-1409
-
-
De Benedetti, F.1
Pignatti, P.2
Gerloni, V.3
Massa, M.4
Sartirana, P.5
Caporali, R.6
-
26
-
-
84865441040
-
Risk of significant cytopenias after treatment with tocilizumab in systemic juvenile arthritis patients with a history of macrophage activation syndrome
-
Kessler EA, Vora SS, Verbsky JW: Risk of significant cytopenias after treatment with tocilizumab in systemic juvenile arthritis patients with a history of macrophage activation syndrome. Pediatr Rheumatol Online J 2012, 10:30. 10.1186/1546-0096-10-30
-
(2012)
Pediatr Rheumatol Online J
, vol.10
, pp. 30
-
-
Kessler, E.A.1
Vora, S.S.2
Verbsky, J.W.3
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