Fresh frozen plasma resuscitation provides neuroprotection compared to normal saline in a large animal model of traumatic brain injury and polytrauma

Journal of Neurotrauma

Volumn 32, Issue 5, 2015, Pages 307-313

  Imam, Ayesha ^a   Jin, Guang ^b   Sillesen, Martin ^a,c   Dekker, Simone E ^b,d   Bambakidis, Ted ^b   Hwabejire, John O ^a   Jepsen, Cecilie H ^a   Halaweish, Ihab ^b   Alam, Hasan B ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c Mental Health Center Glostrup   (Denmark)

^d VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

brain; hemorrhage; plasma; resuscitation; trauma

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; FRESH FROZEN PLASMA; SODIUM CHLORIDE; NEUROPROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; BRAIN DAMAGE; BRAIN EDEMA; BRAIN PERFUSION; FEMALE; HEMODYNAMIC PARAMETERS; INTRACRANIAL PRESSURE; LIVER INJURY; MULTIPLE TRAUMA; NEUROPROTECTION; NONHUMAN; OXYGENATION; PERFUSION PRESSURE; PLASMA TRANSFUSION; RESUSCITATION; RIB FRACTURE; SOFT TISSUE INJURY; SWELLING; TRAUMATIC BRAIN INJURY; YORKSHIRE PIG; ANIMAL; BRAIN INJURIES; DISEASE MODEL; ENZYME LINKED IMMUNOSORBENT ASSAY; PATHOLOGY; PIG; PLASMA; PROCEDURES; SHOCK, HEMORRHAGIC;

ANIMALS; BRAIN INJURIES; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; MULTIPLE TRAUMA; NEUROPROTECTIVE AGENTS; PLASMA; RESUSCITATION; SHOCK, HEMORRHAGIC; SUS SCROFA;

EID: 84924161208     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2014.3535     Document Type: Article

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