Protection against multiple subtypes of influenza viruses by virus-like particle vaccines based on a hemagglutinin conserved epitope

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Chen, Shaoheng ^a   Zheng, Dan ^a   Li, Changgui ^b   Zhang, Wenjie ^c   Xu, Wenting ^a   Liu, Xueying ^a   Fang, Fang ^d   Chen, Ze ^a,d  

^a Shanghai Institute of Biological Products   (China)

^b NATIONAL INSTITUTES FOR FOOD AND DRUG CONTROL   (China)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

^d HUNAN NORMAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; HEPATITIS B CORE ANTIGEN; INFLUENZA VIRUS HEMAGGLUTININ; LONG ALPHA HELIX HEPATITIS B VIRUS CORE VIRUS LIKE PARTICLE VACCINE; UNCLASSIFIED DRUG; VIRUS LIKE PARTICLE VACCINE; CORE PROTEIN; HEMAGGLUTININ; INFLUENZA VACCINE; RECOMBINANT PROTEIN; VIRUS ANTIBODY;

2009 H1N1 INFLUENZA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; IMMUNE RESPONSE; IMMUNIZATION; INFLUENZA A; INFLUENZA A VIRUS (A/PUERTO RICO/8/1934(H1N1)); INFLUENZA VIRUS A H9N2; MAJOR IMMUNODOMINANT REGION; MOUSE; NONHUMAN; PROTEIN STRUCTURE; ANIMAL; BAGG ALBINO MOUSE; GENETICS; HEPATITIS B VIRUS; IMMUNOLOGY; INFLUENZA A VIRUS; ORTHOMYXOVIRUS INFECTION; PROCEDURES; VACCINATION;

AVES; HEPATITIS B VIRUS; MUS; ORTHOMYXOVIRIDAE;

ANIMALS; ANTIBODIES, VIRAL; EPITOPES; ESCHERICHIA COLI; FEMALE; HEMAGGLUTININS; HEPATITIS B VIRUS; IMMUNIZATION; INFLUENZA A VIRUS; INFLUENZA VACCINES; MICE; MICE, INBRED BALB C; ORTHOMYXOVIRIDAE INFECTIONS; RECOMBINANT PROTEINS; VACCINATION; VACCINES, VIRUS-LIKE PARTICLE; VIRAL CORE PROTEINS;

EID: 84924129301     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/901817     Document Type: Article

References (27)

1. L. C. Lambert and A. S. Fauci, "Influenza vaccines for the future," New England Journal of Medicine, vol. 363, no. 21, pp. 2036-2044, 2010.
2. J. Fan, X. Liang, M. S. Horton et al., "Preclinical study of influenza virus aM2 peptide conjugate vaccines in mice, ferrets, and rhesusmonkeys," Vaccine, vol. 22, no. 23-24, pp. 2993-3003, 2004.
3. D. C. Wraith, A. E. Vessey, and B. A. Askonas, "Purified influenza virus nucleoprotein protects mice from lethal infection," Journal of General Virology, vol. 68, no. 2, pp. 433-440, 1987.
4. Z. Sui, Q. Chen, R. Wu et al., "Cross-protection against influenza virus infection by intranasal administration of M2-based vaccine with chitosan as an adjuvant," Archives of Virology, vol. 155, no. 4, pp. 535-544, 2010.
5. L. Guo, M. Zheng, Y. Ding et al., "Protection against multiple influenza A virus subtypes by intranasal administration of recombinant nucleoprotein," Archives of Virology, vol. 155, no. 11, pp. 1765-1775, 2010.
6. Q. Chen, H. Kuang, H. Wang et al., "Comparing the ability of a series of viral protein-expressing plasmid DNAs to protect against H5N1 influenza virus," Virus Genes, vol. 38, no. 1, pp. 30-38, 2009.
7. Z. Sui, Q. Chen, F. Fang, M. Zheng, and Z. Chen, "Crossprotection against influenza virus infection by intranasal administration of M1-based vaccine with chitosan as an adjuvant," Vaccine, vol. 28, no. 48, pp. 7690-7698, 2010.
8. D. C. Ekiert, G. Bhabha, M.-A. Elsliger et al., "Antibody recognition of a highly conserved influenza virus epitope," Science, vol. 324, no. 5924, pp. 246-251, 2009.
9. J. Sui, W. C. Hwang, S. Perez et al., "Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses," Nature Structural and Molecular Biology, vol. 16, no. 3, pp. 265-273, 2009.
10. C. Dreyfus, N. S. Laursen, T. Kwaks et al., "Highly conserved protective epitopes on influenza B viruses," Science, vol. 337, no. 6100, pp. 1343-1348, 2012.
11. G. Bommakanti, M. P. Citron, R. W. Hepler et al., "Design of an HA2-based Escherichia coli expressed influenza immunogen that protects mice from pathogenic challenge," Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 31, pp. 13701-13706, 2010.
12. J. Steel, A. C. Lowen, T. T. Wang et al., "Influenza virus vaccine based on the conserved hemagglutinin stalk domain," mBio, vol. 1, no. 1, 2010.
13. C.-J. Wei, J. C. Boyington, P. M. McTamney et al., "Induction of broadly neutralizing H1N1 influenza antibodies by vaccination," Science, vol. 329, no. 5995, pp. 1060-1064, 2010.
14. Y. Okuno, Y. Isegawa, F. Sasao, and S. Ueda, "A common neutralizing epitope conserved between the hemagglutinins of influenza A virus H1 and H2 strains," Journal of Virology, vol. 67, no. 5, pp. 2552-2558, 1993.
15. G. Bommakanti, X. Lu, M. P. Citronet al., "Designof Escherichia coli-expressed stalk domain immunogens of H1N1 hemagglutinin that protect mice from lethal challenge," Journal of Virology, vol. 86, no. 24, pp. 13434-13444, 2012.
16. A. Schneemann, J. A. Speir, G. S. Tan et al., "A virus-like particle that elicits cross-reactive antibodies to the conserved stem of influenza virus hemagglutinin," Journal of Virology, vol. 86, no. 21, pp. 11686-11697, 2012.
17. V. V. A. Mallajosyula, M. Citron, X. Lu, J. T. Meulen, R. Varadarajan, and X. Liang, "In vitro and in vivo characterization of designed immunogens derived from the CD-helix of the stem of influenza hemagglutinin," Proteins: Structure, Function and Bioinformatics, vol. 81, no. 10, pp. 1759-1775, 2013.
18. E. Bianchi, X. Liang, P. Ingallinella et al., "Universal influenza B vaccine based on the maturational cleavage site of the hemagglutinin precursor," Journal of Virology, vol. 79, no. 12, pp. 7380-7388, 2005.
19. P. Pumpens and E. Grens, "HBV core particles as a carrier for B cell/T cell epitopes," Intervirology, vol. 44, no. 2-3, pp. 98-114, 2001.
20. R. Lamb and R. Krug, "Orthomyxoviridae: the viruses and their replication," in Fields Virology, B. Fields, D. Knipe, and PHowley, Eds., Lippincott-Raven, Philadelphia, Pa, USA, 1996.
21. R. G. Webster, W. J. Bean, O. T. Gorman, T. M. Chambers, and Y. Kawaoka, "Evolution and ecology of influenza a viruses," Microbiological Reviews, vol. 56, no. 1, pp. 152-179, 1992.
22. S. Tong, X. Zhu, Y. Li, M. Shi, J. Zhang, and M. Bourgeoisetal, "New world bats harbor diverse inluenza A viruses," PLoS Pathogens, vol. 9, no. 10, Article ID e1003657, 12 pages, 2013.
23. F. S. Dawood, S. Jain, L. Finelli et al., "Emergence of a novel swine-origin influenza A (H1N1) virus in humans," The New England Journal of Medicine, vol. 360, no. 25, pp. 2605-2615, 2009.
24. G. Chowell, S. M. Bertozzi, M. A. Colchero et al., "Severe respiratory disease concurrent with the circulation of H1N1 influenza," The New England Journal of Medicine, vol. 361, no. 7, pp. 674-679, 2009.
25. K. Subbarao, A. Klimov, J. Katz et al., "Characterization of an avian influenza A (H5N1) virus isolated froma child with a fatal respiratory illness," Science, vol. 279, no. 5349, pp. 393-396, 1998.
26. A.-N. Abdel-Ghafar, T. Chotpitayasunondh, Z. Gao et al., "Update on avian influenza A (H5N1) virus infection in humans," The New England Journal of Medicine, vol. 358, no. 3, pp. 220-273, 2008.
27. K. M. Butt, G. J. D. Smith, H. Chen et al., "Human infection with an avian H9N2 influenza A virus in Hong Kong in 2003," Journal of Clinical Microbiology, vol. 43, no. 11, pp. 5760-5767, 2005.