Krill oil: Evidence of a new source of polyunsaturated fatty acids with high bioavailability

Clinical Lipidology

Volumn 10, Issue 1, 2015, Pages 1-4

  Cicero, Arrigo F G ^a   Colletti, Alessandro ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

brain function; DHA; EPA; fatty acids; fish oil; hyperlipidemia; inflammation; krill oil; non alcoholic fatty liver disease; omega 3; omega 6

Indexed keywords

ASTAXANTHIN; C REACTIVE PROTEIN; CHOLESTEROL; DOCOSAHEXAENOIC ACID; FISH OIL; IBUPROFEN; ICOSAPENTAENOIC ACID; KRILL OIL; LIPID; MENHADEN OIL; OMEGA 3 FATTY ACID; OXYGEN RADICAL; PARACETAMOL; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID; POLYUNSATURATED FATTY ACID; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

CARDIOVASCULAR DISEASE; CHOLESTEROL BLOOD LEVEL; COGNITION; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; EDITORIAL; EUPHAUSIA SUPERBA; HUMAN; HYPERCHOLESTEROLEMIA; INFLAMMATION; LIPID BLOOD LEVEL; MEMORY; MENSTRUATION DISORDER; OSTEOARTHRITIS; PREMENSTRUAL SYNDROME; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RHEUMATOID ARTHRITIS; TRIACYLGLYCEROL BLOOD LEVEL;

EUPHAUSIACEA;

EID: 84924119654     PISSN: 17584299     EISSN: 17584302     Source Type: Journal    
DOI: 10.2217/clp.14.67     Document Type: Editorial

References (20)

1. Cicero AF, De Sando V, Parini A, Borghi C. Polyunsaturated fatty acids application in internal medicine: beyond the established cardiovascular effects. Arch. Med. Sci. 8, 784-793 (2012).
2. Cicero AF, Ertek S, Borghi C. Omega-3 polyunsaturated fatty acids: their potential role in blood pressure prevention and management. Curr. Vasc. Pharmacol. 7, 330-337 (2009).
3. Cicero AF, Morbini M, Borghi C. Do we need "new" omega 3 polyunsaturated fatty acids formulations? Exp. Opin. Pharmacother. (2015) (In Press).
4. Ramprasath VR, Eyal I, Zchut S, Jones PJH. Enhanced increase of omega 3 index in healthy individuals with response to 4 week n-3 fatty acid supplementation from krill oil versus fish oil. Lipids Health Dis. 12, 178 (2013).
5. Naguib YM. Antioxidant activities of astaxanthin and related carotenoids. J. Agric. Food Chem. 48, 1150-1154 (2000).
6. Ulven SM, Kirkhus B, Lamglait A et al. Metabolic effects of krill oil are essentially similar to those of fish oil but at lower dose of EPA and DHA, in healthy volunteers. Lipids 46, 37-46 (2011).
7. Bunea R, El Farrah K, Deutsch L. Evaluation of the Effects of neptune krill oil on the clinical course of hyperlipidemia. Alt. Med. Rev. 9, 420-428 (2004).
8. Berge K, Piscitelli F, Hoem N et al. Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men. Lipids Health Dis. 12, 78 (2013).
9. Deutsch L. Evaluation of the effect of Neptune Krill Oil on chronic inflammation and arthritic symptoms. J. Am. Coll. Nutr. 26, 39-48 (2007).
10. Matias I, Petrosino S, Racioppi A, Capasso R, Izzo AA, Di Marzo V. Dysregulation of peripheral endocannabinoid levels in hyperglycemia and obesity: effect of high fat diets. Mol. Cell. Endocrinol. 286, S66-S78 (2008).
11. Annuzzi G, Piscitelli F, Di Marino L et al. Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients. Lipids Health Dis. 9, 43 (2010).
12. Di Marzo V, Cote M, Matias I et al. Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: associations with changes in metabolic risk factors. Diabetologia 52, 213-217 (2009).
13. Sipe JC, Scott TM, Murray S et al. Biomarkers of endocannabinoid system activation in severe obesity. PLoS ONE 5, e8792 (2010).
14. Banni S, Carta G, Murru E et al. Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects. Nutr. Metab. 8, 7 (2011).
15. Sampalis F, Bunea R, Pelland MF, Kowalski O, Duguet N, Dupuis S. Evaluation of the effects of Neptune Krill Oil™ on the Management of premenstrual syndrome and dysmenorrhea. Alt. Med. Rev. 8, 171-179 (2003).
16. Konagai C, Yanagimoto K, Hayamizu K, Han L, Tsuji T, Koga Y. Effects of krill oil containing n-3 polyunsaturated fatty acids in phospholipid form on human brain function: a randomized controlled trial in healthy elderly volunteers. Clin. Interv. Aging 8, 1247-1257 (2013).
17. Kidd PM. Omega-3 DHA and EPA for cognition, behavior, and mood: clinical findings and structural-functional synergies with cell membrane phospholipids. Alt. Med. Rev. 12, 207-227 (2007).
18. Westerhof W, van Ginkel CJ, Cohen EB, Mekkes JR. Prospective randomized study comparing the debriding effect of krill enzymes and a non-enzymatic treatment in venous leg ulcers. Dermatologica 181, 293-297 (1990).
19. Ferramosca A, Zara V. A krill oil supplemented diet reduces the activities of the mitochondrial tricarboxylate carrier and of the cytosolic lipogenic enzymes in rats. J. Anim. Physiol. Anim. Nutr. 96, 295-306 (2012).
20. Ferramosca A, Zara V. Modulation of hepatic steatosis by dietary fatty acids. World J. Gastroenterol. 20, 1746-1755 (2014).