Complex patterns of abnormal heartbeats

Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics

Volumn 66, Issue 3, 2002, Pages

  Schulte Frohlinde, Verena ^a,b   Ashkenazy, Yosef ^a,c   Goldberger, Ary L ^b   Ivanov, Plamen Ch ^a   Costa, Madalena ^b   Morley Davies, Adrian ^d   Stanley, H Eugene ^a   Glass, Leon ^e  

^a Boston University   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d Department of Clinical Radiology   (United Kingdom)

^e MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARTIFICIAL HEART PACEMAKER; BIOPHYSICS; CARDIOVASCULAR FUNCTION; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGY; HEART; HEART ARRHYTHMIA; HEART DISEASES; HEART RATE; HUMAN; PHYSIOLOGY; PROCEDURES; TIME;

ARRHYTHMIAS, CARDIAC; BIOPHYSICAL PHENOMENA; BIOPHYSICS; CARDIOVASCULAR PHYSIOLOGICAL PHENOMENA; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGY; HEART; HEART DISEASES; HEART RATE; HUMANS; PACEMAKER, ARTIFICIAL; TIME FACTORS;

EID: 84924094022     PISSN: 1063651X     EISSN: None     Source Type: Journal    
DOI: 10.1103/PhysRevE.66.031901     Document Type: Article

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30. The sinus beat interval is computed from the average of four consecutive sinus beats where concealed sinus beats are included. Since not all sinus beat intervals are equally probable, we normalized each line in each of the gray scale plots by dividing by the corresponding value in the sinus beat interval histogram. In constructing the gray scale plots, we collect all episodes with the same sinus beat interval independent of the time of day at which they occur. For long sinus beat intervals, both in the clinical records and in the models to follow, it often happens that the sinus beat following an ectopic beat is not blocked. Such beats are called interpolated sinus beats. When counting the numbers of sinus beats between ectopic beats, we do not include the interpolated beats in this count.
31. Numerical simulations of the models are carried out for each mechanism with sinus cycle lengths from 0.5 s to 1.25 s. Each sinus cycle length is simulated for 1000 beats and then increased by (Formula presented), the typical resolution of clinical records. This amounts to 96 000 sinus beats, which span a time period of 83 625 s (that is almost (Formula presented). As refractory time we choose (Formula presented), a value typically found in clinical data.
32. To realize a random distribution of V beats we choose equally distributed random numbers between 0 and 1, sort them, and then multiply them with the length of the time period under consideration (Formula presented). We choose to have a probability of V beats of 0.5 per second, and therefore we generate (Formula presented) V beats.
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