Exploring dangerous connections between Klebsiella pneumoniae biofilms and healthcare-associated infections

Pathogens

Volumn 3, Issue 3, 2014, Pages 720-731

  Bandeira, Maria ^a   Carvalho, Patricia Almeida ^a   Duarte, Aida ^b   Jordao, Luisa ^c  

^a INSTITUTO SUPERIOR TÉCNICO   (Portugal)

^b RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^c NATIONAL INSTITUTE OF HEALTH DR RICARDO JORGE   (Portugal)

Author keywords

Antibiotic resistance; Biofilm; Healthcare associated infections (HAI); Scanning electron microscopy (SEM)

Indexed keywords

ADHESIN; AMOXICILLIN; FOSFOMYCIN; GENTAMICIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BIOFILM; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FIMBRIA; HEALTHCARE ASSOCIATED INFECTION; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY;

EID: 84923997523     PISSN: None     EISSN: 20760817     Source Type: Journal    
DOI: 10.3390/pathogens3030720     Document Type: Article

References (23)

1. European Centre for Disease Prevention and Control. Annual Epidemiological Report 2012, Reporting on 2010 Surveillance Data and 2011 Epidemic Intelligence Data; ECDC: Stockholm, Sweden, 2013.
2. European Centre for Disease Prevention and Control. Surveillance of Surgical Site Infections in European Hospitals-HAISSI Protocol, Protocol Version 1.02; ECDC: Stockholm, Sweden, 2012.
3. Donlan, R.M. Biofilms: Microbial life on surfaces. Emerg. Infect. Dis. J. 2002, 8, 881-890.
4. Donlan, R.M.; Costerton, J.W. Biofilms: Survival mechanisms of clinically relevant microorganisms. Clin. Microbiol. Rev. 2002, 15, 167-193.
5. Peleg, A.Y.; Hooper, D.C. Hospital-Acquired Infections Due to Gram-Negative Bacteria. N. Engl. J. Med. 2010, 362, 1804-1813.
6. Bales, P.M.; Renke, E.M.; May, S.L.; Shen, Y.; Nelson, D.C. Purification and characterization of biofilm-associated EPS Exopolysaccharides from ESKAPE organisms and other pathogens. PLoS One 2013, 8, e67950.
7. Pomakov, A.O.; Hsiao, C.-B.; Beanan, J.M.; Olson, R.; MacDonald, U.; Keynan, Y.; Russo, T.A. Clinical and phenotypic differences between classic and hypervirulent Klebsiella pneumonia: An emerging and under-recognized pathogenic variant. Eur. J. Clin. Microbiol. Infect. Dis. 2012, 31, 981-989.
8. Chen, P.; Seth, A.K.; Abercrombie, J.J.; Mustoe, T.A.; Leung, K.P. Activity of Imipenem against Klebsiella pneumoniae Biofilms In Vitro and In Vivo. Antimicrob. Agents Chemother. 2014, 58, 1208-1213.
9. Schroll, C.; Barken, K.B.; Karen, A.K.; Struve, C. Role of type1 and type 3 fimbriae in Klebsiella pneumoniae biofilm formation. BMC Microbiol. 2010, 10, 179-188.
10. Stahlhut, S.G.; Chattopadhyay, S.; Kisiela, D.I.; Hvidtfeldt, K.; Clegg, S.; Struve, C.; Sokurenko, E.V.; Krogfelta, K.A. Structural and Population Characterization of MrkD, the Adhesive Subunit of Type 3 Fimbriae. J. Bacteriol. 2013, 195, 5602-5613.
11. Watnick, P.; Kolter, R. Biofilm, city of microbes. J. Bacteriol. 2000, 182, 2675-2679.
12. Reichelt, M.; Joubert, L.; Perrino, J.; Koh, A.L.; Phanwar, I.; Arvin, A.M. 3D reconstruction of VZV infected cell nuclei and PML nuclear cages by serial section array scanning electron microscopy and electron tomography. PLoS Pathog. 2012, 8, e1002740.
13. Jefferson, K.K. What drives bacteria to produce a biofilm? FEMS Microbiol. Lett. 2004, 236, 163-173.
14. Høiby, N.; Bjarnsholt, T.; Givskov, M.; Molin, S.; Ciofu, O. Antibiotic resistance of bacterial biofilms. Int. J. Antimicrob. Agents 2010, 35, 322-332.
15. Lewis, K. Riddle of biofilm resistance. Antimicrob. Agents Chemother. 2001, 45, 999-1007.
16. Antonia, C.K.; Petros, I.R.; Vouloumanou, E.K.; Gkegkes, I.D.; Falagas, M.E. Synergy of fosfomycin with other antibiotics for Gram-positive and Gram-negative bacteria. Eur. J. Clin. Pharmacol. 2010, 66, 359-368.
17. Caneiras, C.; Calisto, F.; Narciso, A.; Arriaga, S.; Melo-Cristino, J.; Duarte, A. Resistance and Virulence Characterisation of CTX-M15 and KPC-3 Klebsiella pneumoniae Clinical Isolates. In Proceedings of the 21st European Congress of Clinical Microbiology and Infectious Diseases, Milan, Italy, 7-10 May, 2011.
18. Endimiani, A.; Patel, G.; Hujer, K.M.; Swaminathan, M.; Perez, F.; Rice, L.B.; Jacobs, M.R.; Bonomo, R.A. In vitro activity of fosfomycin against blaKPC-containing Klebsiella pneumoniae isolates, including those nonsusceptible to tigecycline and/or colistin. Antimicrob. Agents Chemother. 2010, 54, 526-529.
19. De Araujo, C.; Balestrino, D.; Roth, L.; Charbonnel, N.; Forestier, C. Quorum sensing affects biofilm formation through lipopolysaccharide synthesis in Klebsiella pneumoniae. Res. Microbiol. 2010, 161, 595-603.
20. Wu, K.M.; Li, L.H.; Yan, J.J.; Tsao, N.; Liao, T.L.; Tsai, H.C.; Fung, C.P.; Chen, H.J.; Liu, Y.M.; Wang, J.T., et al. Genome sequencing and comparative analysis of Klebsiella pneumoniae NTUH-K2044, a strain causing liver abscess and meningitis. J. Bacteriol. 2009, 191, 4492-4501.
21. Arakawa, Y.; Wacharotayankun, R.; Nagatsuka, T.; Ito, H.; Kato, N.; Ohta, M. Genomic Organization of the Klebsiella pneumoniae cps Region Responsible for Serotype K2 Capsular Polysaccharide Synthesis in the Virulent Strain Chedid. J. Bacteriol. 1995, 177, 1788-1796.
22. Stepanovic, S.; Vukovic, D.; Dakic, I.; Savic, B.; Svabic-Vlahovic, M. A modified microtiter-plate test for quantification of staphylococcal biofilm formation. J. Microbiol. Methods 2000, 40, 175-179.
23. Etienne, G.; Laval, F.; Villeneuve, C.; Dinadayala, P.; Abouwarda, A.; Zerbib, D.; Galamba, A.; Daffé, M. The cell envelope structure and properties of Mycobacterium smegmatis mc2 155: Is there a clue for the unique transformability of the strain? Microbiology 2005, 151, 2075-2086.