Pathogenic ischemic stroke phenotypes in the NINDS-stroke genetics network

Stroke

Volumn 45, Issue 12, 2014, Pages 3589-3596

  Ay, Hakan ^a,b   Arsava, Ethem Murat ^a   Andsberg, Gunnar ^c   Benner, Thomas ^a   Brown, Robert D ^d   Chapman, Sherita N ^e   Cole, John W ^g   Delavaran, Hossein ^c   Dichgans, Martin ^h   Engström, Gunnar ⁱ   Giralt Steinhauer, Eva ^j   Grewal, Raji P ^k   Gwinn, Katrina ^l   Jern, Christina ^m   Jimenez Conde, Jordi ^j   Jood, Katarina ⁿ   Katsnelson, Michael ^o   Kissela, Brett ^p   Kittner, Steven J ^g   Kleindorfer, Dawn O ^p   Labovitz, Daniel L ^q   Lanfranconi, Silvia ^r   Lee, Jin Moo ^s   Lehm, Manuel ^h   Lemmens, Robin ^t   Levi, Chris ^u   Li, Linxin ^v   Lindgren, Arne ^c   Markus, Hugh S ^w   McArdle, Patrick F ^g   Melander, Olle ^c   Norrving, Bo ^c,i   Peddareddygari, Leema Reddy ^k   Pedersén, Annie ^m   Pera, Joanna ^x   Rannikmäe, Kristiina ^y   Rexrode, Kathryn M ^z   Rhodes, David ^aa   Rich, Stephen S ^e   Roquer, Jaume ^b   Rosand, Jonathan ^j   Rothwell, Peter M ^v   Rundek, Tatjana ^o   Sacco, Ralph L ^o   Schmidt, Reinhold ^ab   Schürks, Markus ^ac   Seiler, Stephan ^ab   Sharma, Pankaj ^ad   Slowik, Agnieszka ^x   Sudlow, Cathie ^y   Thijs, Vincent ^t   Woodfield, Rebecca ^y   Worrall, Bradford B ^e,f   Meschia, James F ^ae   more..

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

^d MAYO CLINIC ROCHESTER   (United States)

^e UNIVERSITY OF VIRGINIA   (United States)

^f UNIVERSITY OF VIRGINIA   (United States)

^g UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^h LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

ⁱ LUND UNIVERSITY   (Sweden)

^j UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^k ST FRANCIS MEDICAL CENTER   (United States)

^l NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^m UNIVERSITY OF GOTHENBURG   (Sweden)

ⁿ UNIVERSITY OF GOTHENBURG   (Sweden)

^o UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^p UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^q ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^r FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^s WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^t UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^u UNIVERSITY OF NEWCASTLE   (Australia)

^v UNIVERSITY OF OXFORD   (United Kingdom)

^w UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^x JAGIELLONIAN UNIVERSITY   (Poland)

^y UNIVERSITY OF EDINBURGH   (United Kingdom)

^z BRIGHAM AND WOMEN S HOSPITAL   (United States)

^aa UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^ab MEDICAL UNIVERSITY OF GRAZ   (Austria)

^ac UNIVERSITY HOSPITAL ESSEN   (Germany)

^ad IMPERIAL COLLEGE LONDON   (United Kingdom)

^ae MAYO CLINIC   (United States)

more..

Author keywords

Classification; Pathogenesis; Phenotype

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; CLINICAL PROTOCOL; DISEASE CLASSIFICATION; EUROPEAN; FEMALE; GENETICS; GEOGRAPHIC DISTRIBUTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PHENOTYPE; PRIORITY JOURNAL; RACE DIFFERENCE; RELIABILITY; SEX DIFFERENCE; CLASSIFICATION; NATIONAL HEALTH ORGANIZATION; PATHOLOGY; STROKE; UNITED STATES; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; MALE; MIDDLE AGED; NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE; PHENOTYPE; STROKE; UNITED STATES;

EID: 84923882836     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.114.007362     Document Type: Article

References (16)

1. Gschwendtner A, Bevan S, Cole JW, Plourde A, Matarin M, Ross-Adams H, et al; International Stroke Genetics Consortium. Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke. Ann Neurol. 2009;65:531-539.
2. International Stroke Genetics Consortium (ISGC), Wellcome Trust Case Control Consortium 2 (WTCCC2), Bellenguez C, Bevan S, Gschwendtner A, Spencer CC, et al. Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet. 2012;44:328-333.
3. Holliday EG, Maguire JM, Evans TJ, Koblar SA, Jannes J, Sturm JW, et al; Australian Stroke Genetics Collaborative; International Stroke Genetics Consortium; Wellcome Trust Case Control Consortium 2 Common variants at 6p21.1 are associated with large artery atherosclerotic stroke. Nat Genet. 2012;44:1147-1151.
4. Lubitz SA, Yi BA, Ellinor PT. Genetics of atrial fibrillation. Heart Fail Clin. 2010;6:239-247.
5. Gudbjartsson DF, Arnar DO, Helgadottir A, Gretarsdottir S, Holm H, Sigurdsson A, et al. Variants conferring risk of atrial fibrillation on chromosome 4q25. Nature. 2007;448:353-357.
6. Goldstein LB, Jones MR, Matchar DB, Edwards LJ, Hoff J, Chilukuri V, et al. Improving the reliability of stroke subgroup classification using the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) criteria. Stroke. 2001;32:1091-1098.
7. Gordon DL, Bendixen BH, Adams HP Jr, Clarke W, Kappelle LJ, Woolson RF. Interphysician agreement in the diagnosis of subtypes of acute ischemic stroke: implications for clinical trials. The TOAST Investigators. Neurology. 1993;43:1021-1027.
8. Lindley RI, Warlow CP, Wardlaw JM, Dennis MS, Slattery J, Sandercock PA. Interobserver reliability of a clinical classification of acute cerebral infarction. Stroke. 1993;24:1801-1804.
9. Atiya M, Kurth T, Berger K, Buring JE, Kase CS; Women's Health Study. Interobserver agreement in the classification of stroke in the Women's Health Study. Stroke. 2003;34:565-567.
10. Selvarajah JR, Glaves M, Wainwright J, Jha A, Vail A, Tyrrell PJ. Classification of minor stroke: intra- and inter-observer reliability. Cerebrovasc Dis. 2009;27:209-214.
11. Meschia JF, Barrett KM, Chukwudelunzu F, Brown WM, Case LD, Kissela BM, et al; Siblings with Ischemic Stroke Study (SWISS) Investigators. Interobserver agreement in the trial of org 10172 in acute stroke treatment classification of stroke based on retrospective medical record review. J Stroke Cerebrovasc Dis. 2006;15:266-272.
12. Ay H, Furie KL, Singhal A, Smith WS, Sorensen AG, Koroshetz WJ. An evidence-based causative classification system for acute ischemic stroke. Ann Neurol. 2005;58:688-697.
13. Ay H, Benner T, Arsava EM, Furie KL, Singhal AB, Jensen MB, et al. A computerized algorithm for etiologic classification of ischemic stroke: the Causative Classification of Stroke System. Stroke. 2007;38:2979-2984.
14. Arsava EM, Ballabio E, Benner T, Cole JW, Delgado-Martinez MP, Dichgans M, et al; International Stroke Genetics Consortium. The Causative Classification of Stroke system: an international reliability and optimization study. Neurology. 2010;75:1277-1284.
15. Meschia JF, Arnett DK, Ay H, Brown RD Jr, Benavente OR, Cole JW, et al; NINDS SiGN Study. Stroke Genetics Network (SiGN) study: design and rationale for a genome-wide association study of ischemic stroke subtypes. Stroke. 2013;44:2694-2702.
16. Cohen J. A coefficient of agreement for nominal scales. Educ Psychol Meas. 1960;20:37-46.