Role of G-CSF GM-CSF in the management of infections in preterm newborns: An update

Early Human Development

Volumn 90, Issue , 2014, Pages S15-S17

  Castagnola, Elio ^a   Dufour, Carlo ^a  

^a G GASLINI INSTITUTE   (Italy)

Author keywords

G CSF; GM CSF; Growth factor; Neonate; Neutropenia; Sepsis

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

HUMAN; INFECTION PREVENTION; LOW BIRTH WEIGHT; NEUTROPENIA; NEUTROPHIL COUNT; NEWBORN; NEWBORN INFECTION; POLYMORPHONUCLEAR CELL; PREMATURITY; REVIEW; SMALL FOR DATE INFANT; SEPSIS;

GRANULOCYTE COLONY-STIMULATING FACTOR; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; NEUTROPENIA; SEPSIS;

EID: 84923869471     PISSN: 03783782     EISSN: 18726232     Source Type: Journal    
DOI: 10.1016/S0378-3782(14)50005-9     Document Type: Article

References (16)

1. Fioredda F., Calvillo M., Bonanomi S., Coliva T., Tucci F., Farruggia P., et al. Congenital and acquired neutropenia consensus guidelines on diagnosis from the Neutropenia Committee of the Marrow Failure Syndrome Group of the AIEOP (Associazione Italiana Emato-Oncologia Pediatrica). Pediatr Blood Cancer 2011, 57:10-17.
2. Christensen R.D., Henry E., Wiedmeier S.E., Stoddard R.A., Lambert D.K. Low blood neutrophil concentrations among extremely low birth weight neonates: data from a multihospital health-care system. J Perinatol 2006, 26:682-687.
3. Funke A., Berner R., Traichel B., Schmeisser D., Leititis J.U., Niemeyer C.M. Frequency, natural course, and outcome of neonatal neutropenia. Pediatrics 2000, 106:45-51.
4. Del Vecchio A., Christensen R.D. Neonatal neutropenia: what diagnostic evaluation is needed and when is treatment recommended?. Early Hum Dev 2012, 88(Suppl 2):S19-S24.
5. Molloy E.J., O'Neill A.J., Grantham J.J., Sheridan-Pereira M., Fitzpatrick J.M., Webb D.W., et al. Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor have differential effects on neonatal and adult neutrophil survival and function. Pediatr Res 2005, 57:806-812.
6. Ahmad M., Fleit H.B., Golightly M.G., La Gamma E.F. In vivo effect of recombinant human granulocyte colony-stimulating factor on phagocytic function and oxidative burst activity in septic neutropenic neonates. Biol Neonate 2004, 86:48-54.
7. Carr R., Modi N., Dore C. G-CSF and GM-CSF for treating or preventing neonatal infections. Cochrane Database Syst Rev. 2003, 3. CD003066.
8. Kuhn P., Messer J., Paupe A., Espagne S., Kacet N., Mouchnino G., et al. A multicenter, randomized, placebo-controlled trial of prophylactic recombinant granulocyte-colony stimulating factor in preterm neonates with neutropenia. J Pediatr 2009, 155:324-330.
9. Carr R., Brocklehurst P., Dore C., Modi N. Granulocyte-macrophage colony stimulating factor administered as prophylaxis for reduction of sepsis in extremely preterm, small for gestational age neonates (the PROGRAMS trial): a single-blind, multicentre, randomised controlled trial. Lancet 2009, 373:226-233.
10. Marlow N., Morris T., Brocklehurst P., Carr R., Cowan F.M., Patel N., et al. A randomised trial of granulocyte-macrophage colony-stimulating factor for neonatal sepsis: outcomes at 2 years. Arch Dis Child Fetal Neonatal Ed 2013, 98:F46-F53.
11. Bedford Russell A.R., Emmerson A.J., Wilkinson N., Chant T., Sweet D.G., Halliday H.L., et al. A trial of recombinant human granulocyte colony stimulating factor for the treatment of very low birthweight infants with presumed sepsis and neutropenia. Arch Dis Child Fetal Neonatal Ed 2001, 84:F172-F176.
12. Miura E., Procianoy R.S., Bittar C., Miura C.S., Miura M.S., Mello C., et al. A randomized, double-masked, placebo-controlled trial of recombinant granulocyte colony-stimulating factor administration to preterm infants with the clinical diagnosis of early-onset sepsis. Pediatrics 2001, 107:30-35.
13. Nayeri F., Soheili H., Kaveh M., Oloomi Yazdi Z., Shariat M., Dalili H. Comparison of two regimens of RhG-CSF in neutropenic neonatal septicemia: a randomized clinical trial. Acta Med Iran 2011, 49:575-578.
14. Gathwala G., Walia M., Bala H., Singh S. Recombinant human granulocyte colony-stimulating factor in preterm neonates with sepsis and relative neutropenia: a randomized, single-blind, non-placebo-controlled trial. J Trop Pediatr 2012, 58:12-18.
15. Venkateswaran L., Wilimas J.A., Dancy R., Wang W.C., Korones S., Hayden J., et al. Granulocyte-macrophage colony-stimulating factor in the treatment of neonates with neutropenia and sepsis. Pediatr Hematol Oncol 2000, 17:469-473.
16. Ahmad A., Laborada G., Bussel J., Nesin M. Comparison of recombinant granulocyte colony-stimulating factor, recombinant human granulocyte-macrophage colony-stimulating factor and placebo for treatment of septic preterm infacts. Pediatr Infect Dis J 2002, 21:1061-1065.