Genomic imbalances in circulating DNA in Hodgkin's lymphoma

The Lancet Haematology

Volumn 2, Issue 2, 2015, Pages e48-e49

  Hohaus, Stefan ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CIRCULATING CELL FREE DNA; DNA; JANUS KINASE 2; NIVOLUMAB; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 LIGAND 2; UNCLASSIFIED DRUG;

CELL INTERACTION; CHROMOSOME DISORDER; DISEASE ACTIVITY; DNA EXTRACTION; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC HETEROGENEITY; GENETIC PARAMETERS; GENOMIC IMBALANCE; HIGH THROUGHPUT SEQUENCING; HODGKIN DISEASE; HUMAN; MEDIASTINUM MASS; MOLECULAR CLONING; NODULAR SCLEROSIS HODGKIN LYMPHOMA; NON INVASIVE PRENATAL TEST; NOTE; PRIORITY JOURNAL; REED STERNBERG CELL; T LYMPHOCYTE; GENETICS; GENOMICS; LARGE CELL LYMPHOMA; NONHODGKIN LYMPHOMA;

DNA; GENOMICS; HODGKIN DISEASE; HUMANS; LYMPHOMA, LARGE B-CELL, DIFFUSE; LYMPHOMA, NON-HODGKIN;

EID: 84923830321     PISSN: None     EISSN: 23523026     Source Type: Journal    
DOI: 10.1016/S2352-3026(14)00042-8     Document Type: Note

References (8)

1. Vandenberghe P, Wlodarska P, Tousseyn T, et al. Non-invasive detection of genomic imbalances in Hodgkin/Reed-Sternberg cells in early and advanced stage Hodgkin's lymphoma by sequencing of circulating cell-free DNA. Lancet Haematol 2015, published online Jan 20. http://dx.doi.org/10.1016/S2352-3026(14)00039-8.
2. Lo YM, Corbetta N, Chamberlain PF, et al. Presence of fetal DNA in maternal plasma and serum. Lancet 1997, 350:485-487.
3. Schwarzenbach H, Hoon DS, Pantel K Cell-free nucleic acids as biomarkers in cancer patients. Nat Rev Cancer 2011, 11:426-437.
4. Hohaus S, Giachelia M, Massini G, et al. Cell-free circulating DNA in Hodgkin's and non-Hodgkin's lymphomas. Ann Oncol 2009, 20:1408-1413.
5. Kornacker M, Jox A, Vockerodt M, et al. Detection of a Hodgkin/Reed-Sternberg cell specific immunoglobulin gene rearrangement in the serum DNA of a patient with Hodgkin's disease. Br J Haematol 1999, 106:528-531.
6. Murtaza M, Dawson SJ, Tsui DW, et al. Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA. Nature 2013, 497:108-112.
7. Green MR, Monti S, Rodig SJ, et al. Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma. Blood 2010, 116:3268-3277.
8. Ansell SM, Lesokhin AM, Borrello I, et al. PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma. N Engl J Med 2014, published online Dec 6. 10.1056/NEJMoa1411087.