The enigmatic reception of DEET - The gold standard of insect repellents

Current Opinion in Insect Science

Volumn 6, Issue , 2014, Pages 93-98

  Leal, Walter S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CULEX PIPIENS QUINQUEFASCIATUS; HEXAPODA;

EID: 84923807002     PISSN: 22145745     EISSN: 22145753     Source Type: Journal    
DOI: 10.1016/j.cois.2014.10.007     Document Type: Review

References (26)

1. S.J. Moore, and M. Debboun History of insect repellents M. Debboun, S.P. Frances, D. Strickmann, Insect Repellents: Principles, Methods, and Uses 2007 CRC Press Boca Raton, FL 1 29
2. V.G. Dethier, L.B. Browne, and C.N. Smith The designation of chemicals in terms of the responses they elicit from insects J Econ Entomol 53 1960 134 136
3. J.R. Miller, P.Y. Siegert, F.A. Amimo, and E.D. Walker Designation of chemicals in terms of the locomotor responses they elicit from insects: an update of Dethier et al. (1960) J Econ Entomol 102 2009 2056 2060
4. S.I. Gertler N,N-Diethylbenzamide as an Insect Repellent 1944
5. R.K. Gupta, and A.K. Bhattacharjee History of insect repellents M. Debboun, S.P. Frances, D. Strickmann, Insect Repellents: Principles, Methods, and Uses 2007 CRC Press Boca Raton, FL 195 228
6. E.T. McCabe, W.F. Barthell, S.I. Gertler, and S.A. Hall Insect repellents: N,N-dimethylamides J Org Chem 19 1954 493 498
7. D. Jackson, B. Luukinen, K. Buhl, and D. Stone DEET Technical Fact Sheet 2008 National Pesticide Information Center, Oregon State University Extension Services
8. M. Klier, and F. Kuhlow Neue Insektenabwehrmittel - am Stickstoff disubstitutierte ß-Alaninderivative J Soc Cosmet Chem 27 1976 141 153
9. J. Boeckh, H. Breer, M. Geier, F.-P. Hoever, B.W. Kruger, G. Nentwig, and H. Sass Acylated 1,3-aminopropanols as repellents against bloodsucking arthropods Pest Sci 48 1996 359 373
10. Y. Lee, S.H. Kim, and C. Montell Avoiding DEET through insect gustatory receptors Neuron 67 2010 555 561
11. J.P. Grieco, N.L. Achee, T. Chareonviriyaphap, W. Suwonkerd, K. Chauhan, M.R. Sardelis, and D.R. Roberts A new classification system for the actions of IRS chemicals traditionally used for malaria control PLoS ONE 2 2007 e716
12. S.N. Tikar, R. Yadav, M.J. Mendki, A.N. Rao, D. Sukumaran, and B.D. Parashar Oviposition deterrent activity of three mosquito repellents diethyl phenyl acetamide (DEPA), diethyl m-toluamide (DEET), and diethyl benzamide (DEB) on Aedes aegypti, Aedes albopictus, and Culex quinquefasciatus Parasitol Res 113 2014 101 106
13. W.S. Leal Odorant reception in insects: roles of receptors, binding proteins, and degrading enzymes Annu Rev Entomol 58 2013 373 391
14. C. Costantini, M.A. Birkett, G. Gibson, J. Ziesmann, N.F. Sagnon, H.A. Mohammed, M. Coluzzi, and J.A. Pickett Electroantennogram and behavioural responses of the malaria vector Anopheles gambiae to human-specific sweat components Med Vet Entomol 15 2001 259 266
15. W.S. Leal Molecular-based prospecting of mosquito attractants and repellents M. Debboun, S.P. Frances, D. Strickmann, Insect Repellents: Principles, Methods, and Uses 2007 CRC Press Boca Raton, FL 229 242
16. W.S. Leal, and K. Uchida Application of GC-EAD to the determination of mosquito repellents derived from a plant Cymbopogon citratus J Asia-Pac Entomol 1 1998 217 221
17. Z. Syed, and W.S. Leal Mosquitoes smell and avoid the insect repellent DEET Proc Natl Acad Sci U S A 105 2008 13598 13603
18. N.M. Stanczyk, J.F. Brookfield, R. Ignell, J.G. Logan, and L.M. Field Behavioral insensitivity to DEET in Aedes aegypti is a genetically determined trait residing in changes in sensillum function Proc Natl Acad Sci U S A 107 2010 8575 8580
19. E.E. Davis Insect repellents: concepts of their mode of action relative to potential sensory mechanisms in mosquitoes (Diptera: Culicidae) J Med Entomol 22 1985 237 243
20. M. Ditzen, M. Pellegrino, and L.B. Vosshall Insect odorant receptors are molecular targets of the insect repellent DEET Science 319 2008 1838 1842
21. M. Pellegrino, N. Steinbach, M.C. Stensmyr, B.S. Hansson, and L.B. Vosshall A natural polymorphism alters odour and DEET sensitivity in an insect odorant receptor Nature 478 2011 511 514
22. M. DeGennaro, C.S. McBride, L. Seeholzer, T. Nakagawa, E.J. Dennis, C. Goldman, N. Jasinskiene, A.A. James, and L.B. Vosshall orco mutant mosquitoes lose strong preference for humans and are not repelled by volatile DEET Nature 498 2013 487 491
23. P. Kain, S.M. Boyle, S.K. Tharadra, T. Guda, C. Pham, A. Dahanukar, and A. Ray Odour receptors and neurons for DEET and new insect repellents Nature 502 2013 507 512
24. R. Rytz, V. Croset, and R. Benton Ionotropic receptors (IRs): chemosensory ionotropic glutamate receptors in Drosophila and beyond Insect Biochem Mol Biol 43 2013 888 897
25. W.S. Leal, Y.M. Choo, P. Xu, C.S. da Silva, and C. Ueira-Vieira Differential expression of olfactory genes in the southern house mosquito and insights into unique odorant receptor gene isoforms Proc Natl Acad Sci U S A 110 2013 18704 18709
26. P. Xu, Y.M. Choo, A. De La Rosa, and W.S. Leal Mosquito odorant receptor for DEET and methyl jasmonate Proc Natl Acad Sci U S A 2014 10.1073/pnas.1417244111