Chitosan-based electrospun nanofibrous mats, hydrogels and cast films: novel anti-bacterial wound dressing matrices

Journal of Materials Science: Materials in Medicine

Volumn 26, Issue 3, 2015, Pages 1-12

  Shahzad, Sohail ^a   Yar, Muhammad ^b   Siddiqi, Saadat Anwar ^b   Mahmood, Nasir ^c   Rauf, Abdul ^a   Qureshi, Zafar ul Ahsan ^d   Anwar, Muhammad Sabieh ^e   Afzaal, Shahida ^d  

^a THE ISLAMIA UNIVERSITY OF BAHAWALPUR   (Pakistan)

^b COMSATS Institute of Information Technology   (Pakistan)

^c UNIVERSITY OF HEALTH SCIENCES   (Pakistan)

^d Veterinary Research Institute   (Pakistan)

^e LAHORE UNIVERSITY OF MANAGEMENT SCIENCES   (Pakistan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CHITOSAN; DRUG PRODUCTS; HYDROGELS; HYDROXYAPATITE; NANOFIBERS; POLYVINYL ALCOHOLS; PORE SIZE; SCANNING ELECTRON MICROSCOPY; SWELLING; TARGETED DRUG DELIVERY;

AVERAGE DIAMETER; BACTERIAL STRAINS; COMPOSITE MATRICES; DEGREE OF SWELLING; PHOSPHATE BUFFER SALINES; SUSTAINED RELEASE; SYNTHESIZED MATERIALS; WOUND DRESSINGS;

CONTROLLED DRUG DELIVERY;

CEFIXIME; CHITOSAN; HYDROXYAPATITE; NANOFIBER; NEUTRAL RED; PHOSPHATE BUFFERED SALINE; POLYVINYL ALCOHOL; ANTIINFECTIVE AGENT; BIOMATERIAL; HYDROGEL;

ANTIBACTERIAL ACTIVITY; ARTICLE; BIOCOMPATIBILITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; ELECTROSPINNING; FILM; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HYDROGEL; IN VITRO STUDY; INFRARED SPECTROSCOPY; MORPHOLOGY; NONHUMAN; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SUSTAINED DRUG RELEASE; SYNTHESIS; WOUND DRESSING; BANDAGE; CHEMISTRY; WOUNDS AND INJURIES;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; POSIBACTERIA;

ANTI-BACTERIAL AGENTS; BANDAGES; BIOCOMPATIBLE MATERIALS; CHITOSAN; HYDROGELS; MICROSCOPY, ELECTRON, SCANNING; NANOFIBERS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; WOUNDS AND INJURIES;

EID: 84923804248     PISSN: 09574530     EISSN: 15734838     Source Type: Journal    
DOI: 10.1007/s10856-015-5462-y     Document Type: Article

References (52)

1. Song A, Rane AA, Christman KL. Antibacterial and cell-adhesive polypeptide and poly (ethylene glycol) hydrogel as a potential scaffold for wound healing. Acta Biomater. 2012;8:41–50.
2. Lagana G, Anderson EH. Moisture dressings: the new standard in wound care. J Nurse Pract. 2010;6:366–70.
3. Pal K, Banthia AK, Majumdar DK. Polyvinyl alcohol–glycine composite membranes: preparation, characterization, drug release and cytocompatibility studies. Biomed Mater. 2006;1:49.
4. Yu H, Xu X, Chen X, Hao J, Jing X. Medicated wound dressings based on poly (vinyl alcohol)/poly (N-vinyl pyrrolidone)/chitosan hydrogels. J Appl Polym Sci. 2006;101:2453–63.
5. Majno G. The healing hand: man and wound in the ancient world. Cambridge: Harvard University Press; 1991.
6. Boateng JS, Pawar HV, Tetteh J. Polyox and carrageenan based composite film dressing containing anti-microbial and anti-inflammatory drugs for effective wound healing. Int J Pharm. 2013;441:181–91.
7. Fajardo AR, Lopes LC, Caleare AO, Britta EA, Nakamura CV, Rubira AF, et al. Silver sulfadiazine loaded chitosan/chondroitin sulfate films for a potential wound dressing application. Mater Sci Eng C. 2013;33:588–95.
8. Pawar H, Tetteh J, Boateng J. Preparation, optimisation and characterisation of novel wound healing film dressings loaded with streptomycin and diclofenac. Colloids Surf B. 2013;102:102–10.
9. Thu H-E, Zulfakar MH, Ng S-F. Alginate based bilayer hydrocolloid films as potential slow-release modern wound dressing. Int J Pharm. 2012;434:375–83.
10. De Cicco F, Reverchon E, Adami R, Auriemma G, Russo P, Calabrese EC, et al. In situ forming antibacterial dextran blend hydrogel for wound dressing: SAA technology vs. spray drying. Carbohydr Polym. 2014;101:1216–24.
11. Dias A, Braga M, Seabra I, Ferreira P, Gil M, De Sousa H. Development of natural-based wound dressings impregnated with bioactive compounds and using supercritical carbon dioxide. Int J Pharm. 2011;408:9–19.
12. Singh B, Pal L. Sterculia crosslinked PVA and PVA-poly (AAm) hydrogel wound dressings for slow drug delivery: mechanical, mucoadhesive, biocompatible and permeability properties. J Mech Behav Biomed Mater. 2012;9:9–21.
13. Wang T, Zhu X-K, Xue X-T, Wu D-Y. Hydrogel sheets of chitosan, honey and gelatin as burn wound dressings. Carbohydr Polym. 2012;88:75–83.
14. Shalumon K, Anulekha K, Nair SV, Nair S, Chennazhi K, Jayakumar R. Sodium alginate/poly(vinyl alcohol)/nano ZnO composite nanofibers for antibacterial wound dressings. Int J Biol Macromol. 2011;49:247–54.
15. Unnithan AR, Barakat NA, Tirupathi Pichiah P, Gnanasekaran G, Nirmala R, Cha Y-S, et al. Wound-dressing materials with antibacterial activity from electrospun polyurethane–dextran nanofiber mats containing ciprofloxacin HCl. Carbohydr Polym. 2012;90:1786–93.
16. Yang Y, Xia T, Zhi W, Wei L, Weng J, Zhang C, et al. Promotion of skin regeneration in diabetic rats by electrospun core-sheath fibers loaded with basic fibroblast growth factor. Biomaterials. 2011;32:4243–54.
17. Zhao Y, Zhou Y, Wu X, Wang L, Xu L, Wei S. A facile method for electrospinning of Ag nanoparticles/poly (vinyl alcohol)/carboxymethyl-chitosan nanofibers. Appl Surf Sci. 2012;258:8867–73.
18. Kenawy E-R, Layman JM, Watkins JR, Bowlin GL, Matthews JA, Simpson DG, et al. Electrospinning of poly (ethylene-co-vinyl alcohol) fibers. Biomaterials. 2003;24:907–13.
19. Khil MS, Cha DI, Kim HY, Kim IS, Bhattarai N. Electrospun nanofibrous polyurethane membrane as wound dressing. J Biomed Mater Res B. 2003;67:675–9.
20. Matsumoto H, Tanioka A. Functionality in electrospun nanofibrous membranes based on fiber’s size, surface area, and molecular orientation. Membranes. 2011;1:249–64.
21. Li C, Vepari C, Jin H-J, Kim HJ, Kaplan DL. Electrospun silk-BMP-2 scaffolds for bone tissue engineering. Biomaterials. 2006;27:3115–24.
22. Schneider A, Wang X, Kaplan D, Garlick J, Egles C. Biofunctionalized electrospun silk mats as a topical bioactive dressing for accelerated wound healing. Acta Biomater. 2009;5:2570–8.
23. Reneker DH, Yarin AL, Fong H, Koombhongse S. Bending instability of electrically charged liquid jets of polymer solutions in electrospinning. J Appl Phys. 2000;87:4531–47.
24. Haque MA, Kurokawa T, Gong JP. Super tough double network hydrogels and their application as biomaterials. Polymer. 2012;53:1805–22.
25. Ryu JH, Lee Y, Kong WH, Kim TG, Park TG, Lee H. Catechol-functionalized chitosan/pluronic hydrogels for tissue adhesives and hemostatic materials. Biomacromolecules. 2011;12:2653–9.
26. Zhang H, Qadeer A, Chen W. In situ gelable interpenetrating double network hydrogel formulated from binary components: thiolated chitosan and oxidized dextran. Biomacromolecules. 2011;12:1428–37.
27. Kao WJ. Evaluation of protein-modulated macrophage behavior on biomaterials: designing biomimetic materials for cellular engineering. Biomaterials. 1999;20:2213–21.
28. Ruszczak Z. Effect of collagen matrices on dermal wound healing. Adv Drug Deliv Rev. 2003;55:1595–611.
29. Cho Y-W, Han S-S, Ko S-W. PVA containing chito-oligosaccharide side chain. Polymer. 2000;41:2033–9.
30. Kim SJ, Shin SR, Kim NG, Kim SI. Swelling behavior of semi-interpenetrating polymer network hydrogels based on chitosan and poly(acryl amide). J Macromol Sci A. 2005;42:1073–83.
31. Liang S, Liu L, Huang Q, Yam KL. Preparation of single or double-network chitosan/poly (vinyl alcohol) gel films through selectively cross-linking method. Carbohydr Polym. 2009;77:718–24.
32. Yang E, Qin X, Wang S. Electrospun crosslinked polyvinyl alcohol membrane. Mater Lett. 2008;62:3555–7.
33. Chandy T, Sharma CP. Prostaglandin E1-immobilized poly (vinyl alcohol)-blended chitosan membranes: blood compatibility and permeability properties. J Appl Polym Sci. 1992;44:2145–56.
34. Jegal J, Lee KH. Nanofiltration membranes based on poly (vinyl alcohol) and ionic polymers. J Appl Polym Sci. 1999;72:1755–62.
35. Sarvestani AS, Jabbari E. Modeling and experimental investigation of rheological properties of injectable poly (lactide ethylene oxide fumarate)/hydroxyapatite nanocomposites. Biomacromolecules. 2006;7:1573–80.
36. Sugawara A, Yamane S, Akiyoshi K. Nanogel-templated mineralization: polymer-calcium phosphate hybrid nanomaterials. Macromol Rapid Commun. 2006;27:441–6.
37. Sung Y-M, Shin Y-K, Ryu J-J. Preparation of hydroxyapatite/zirconia bioceramic nanocomposites for orthopaedic and dental prosthesis applications. Nanotechnology. 2007;18:065602.
38. Gomez-Vega J, Saiz E, Tomsia A, Marshall G, Marshall S. Bioactive glass coatings with hydroxyapatite and Bioglass particles on Ti-based implants. 1. Processing. Biomaterials. 2000;21:105–11.
39. Rizzi SC, Heath D, Coombes A, Bock N, Textor M, Downes S. Biodegradable polymer/hydroxyapatite composites: surface analysis and initial attachment of human osteoblasts. J Biomed Mater Res. 2001;55:475–86.
40. Lin HR, Yeh YJ. Porous alginate/hydroxyapatite composite scaffolds for bone tissue engineering: preparation, characterization, and in vitro studies. J Biomed Mater Res B. 2004;71:52–65.
41. Queiroz A, Santos JD, Monteiro F. Adsorption isotherm of sodium ampicillin onto dense and porous hydroxyapatite. Key Eng Mater. 2005;284:387–90.
42. Rauschmann MA, Wichelhaus TA, Stirnal V, Dingeldein E, Zichner L, Schnettler R, et al. Nanocrystalline hydroxyapatite and calcium sulphate as biodegradable composite carrier material for local delivery of antibiotics in bone infections. Biomaterials. 2005;26:2677–84.
43. Santos JD, Monteiro F, Queiroz A. Porous HA scaffolds for drug releasing. Key Eng Mater. 2005;284:407–10.
44. Arshad HM, Mohiuddin OA, Azmi MB. Comparative in vitro antibacterial analysis of different brands of cefixime against clinical isolates of Staphylococcus aureus and Escherichia coli. J Appl Pharm Sci. 2012;2:109–13.
45. Bergeron MG, Turcotte A. Penetration of cefixime into fibrin clots and in vivo efficacy against Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus. Antimicrob Agents Chemother. 1986;30:913–6.
46. Knapp CC, Sierra-Madero J, Washington JA. Antibacterial activities of cefpodoxime, cefixime, and ceftriaxone. Antimicrob Agents Chemother. 1988;32:1896–8.
47. Sweetman SC. Martindale: the complete drug reference. 35th ed. London: Pharmaceutical Press; 2007.
48. McMillan A, Young H. The treatment of pharyngeal gonorrhoea with a single oral dose of cefixime. Int J STD AIDS. 2007;18:253–4.
49. Huang M, Zhao X-L. Pharmacokinetics and bioavailability of oral cefiximein healthy adult volunteers. Chin Pharmacol Bull. 1994:01.
50. Murtaza G, Ahmad M, Khan SA, Hussain I. Evaluation of cefixime-loaded chitosan microspheres: analysis of dissolution data using DDSolver. Dissolut Technol. 2012;19:13–9.
51. Reddy AT, Kiran JV, Duraival S, Pragathi Kumar B. Formulation and in-vitro evaluation of cefixime trihydrate sustained release matrix tablets. Int J Curr Pharm Rev Res. 2013;3:110–29.
52. Repetto G, del Peso A, Zurita JL. Neutral red uptake assay for the estimation of cell viability/cytotoxicity. Nat Protoc. 2008;3:1125–31.