The new histopathologic classification of ANCA-associated gn and its association with renal outcomes in childhood

Clinical Journal of the American Society of Nephrology

Volumn 9, Issue 10, 2014, Pages 1684-1691

  Noone, Damien G ^a   Twilt, Marinka ^a   Hayes, Wesley N ^a   Thorner, Paul S ^a   Benseler, Susanne ^a,b   Laxer, Ronald M ^a,b   Parekh, Rulan S ^a,b   Hebert, Diane ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; ANTIHYPERTENSIVE AGENT; AZATHIOPRINE; CREATININE; CYCLOPHOSPHAMIDE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HEMOGLOBIN; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RITUXIMAB; STEROID; NEUTROPHIL CYTOPLASMIC ANTIBODY;

ADOLESCENT; ANCA ASSOCIATED GLOMERULONEPHRITIS; ARTICLE; CHILD; CHILDHOOD; CLINICAL ARTICLE; COHORT ANALYSIS; DIALYSIS; DISEASE ASSOCIATION; DISEASE COURSE; END STAGE RENAL DISEASE; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; FOLLOW UP; GLOMERULONEPHRITIS; GLOMERULUS FILTRATION RATE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; KAPLAN MEIER METHOD; KIDNEY BIOPSY; KIDNEY FUNCTION; MALE; OUTCOME ASSESSMENT; PLASMAPHERESIS; PREDICTION; PROTEIN URINE LEVEL; RETROSPECTIVE STUDY; SCLEROSIS; SURVIVAL; TRANSITION TO ADULT CARE; AGE; BIOPSY; CANADA; CHRONIC KIDNEY FAILURE; CLASSIFICATION; FOCAL GLOMERULOSCLEROSIS; IMMUNOLOGY; KIDNEY; MORTALITY; PATHOLOGY; PATHOPHYSIOLOGY; PREDICTIVE VALUE; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; RENAL INSUFFICIENCY, CHRONIC; REPRODUCIBILITY; RISK FACTOR; TIME; VALIDATION STUDY;

ADOLESCENT; AGE FACTORS; ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; BIOPSY; CHILD; DISEASE PROGRESSION; FEMALE; GLOMERULAR FILTRATION RATE; GLOMERULONEPHRITIS; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; HUMANS; KAPLAN-MEIER ESTIMATE; KIDNEY; KIDNEY FAILURE, CHRONIC; MALE; ONTARIO; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RENAL INSUFFICIENCY, CHRONIC; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES; RISK FACTORS; TIME FACTORS;

EID: 84923793259     PISSN: 15559041     EISSN: 1555905X     Source Type: Journal    
DOI: 10.2215/CJN.01210214     Document Type: Article

References (25)

1. Rottem M, Fauci AS, Hallahan CW, Kerr GS, Lebovics R, Leavitt RY, Hoffman GS: Wegener granulomatosis in children and adolescents: Clinical presentation and outcome. J Pediatr 122: 26–31, 1993.
2. Akikusa JD, Schneider R, Harvey EA, Hebert D, Thorner PS, Laxer RM, Silverman ED: Clinical features and outcome of pediatric Wegener’s granulomatosis. Arthritis Rheum 57: 837–844, 2007.
3. Peco-Antic A, Bonaci-Nikolic B, Basta-Jovanovic G, Kostic M, Markovic-Lipkovski J, Nikolic M, Spasojevic B: Childhood microscopic polyangiitis associated with MPO-ANCA. Pediatr Nephrol 21: 46–53, 2006.
4. Arulkumaran N, Jawad S, Smith SW, Harper L, Brogan P, Pusey CD, Salama AD: Long- term outcome of paediatric patients with ANCA vasculitis. Pediatr Rheumatol Online J 9: 12, 2011.
5. Berden AE, Ferrario F, Hagen EC, Jayne DR, Jennette JC, Joh K, Neumann I, Noël L-H, Pusey CD, Waldherr R, Bruijn JA, Bajema IM: Histopathologic classification of ANCA-associated glomerulonephritis. J Am Soc Nephrol 21: 1628–1636, 2010.
6. Jayne D, Rasmussen N, Andrassy K, Bacon P, Tervaert JW, Dadoniene´ J, Ekstrand A, Gaskin G, Gregorini G, de Groot K, Gross W, Hagen EC, Mirapeix E, Pettersson E, Siegert C, Sinico A, Tesar V, Westman K, Pusey C; European Vasculitis StudyGroup: A randomized trial of maintenance therapy for vasculitis associated with antineutrophil cytoplasmic autoantibodies. N Engl J Med 349: 36–44, 2003.
7. Jayne DR, Gaskin G, Rasmussen N, Abramowicz D, Ferrario F, Guillevin L, Mirapeix E, Savage CO, Sinico RA, Stegeman CA, Westman KW, van der Woude FJ, de Lind van Wijngaarden RA, Pusey CD; European Vasculitis StudyGroup: Randomized trial of plasma exchange or high-dosage methylprednisolone as adjunctive therapy for severe renal vasculitis. J AmSocNephrol 18: 2180–2188, 2007.
8. Aasarød K, Bostad L, Hammerstrøm J, Jørstad S, Iversen BM: Renal histopathology and clinical course in 94 patients with Wegener’s granulomatosis. Nephrol Dial Transplant 16: 953– 960, 2001.
9. de Lind van Wijngaarden RA, Hauer HA, Wolterbeek R, Jayne DR, Gaskin G, Rasmussen N, Noël LH, Ferrario F, Waldherr R, Hagen EC, Bruijn JA, Bajema IM: Clinical and histologic determinants of renal outcome in ANCA-associated vasculitis: A prospective analysis of 100 patients with severe renal involvement. J Am Soc Nephrol 17: 2264–2274, 2006.
10. Hauer HA, Bajema IM, Van Houwelingen HC, Ferrario F, Noe¨ l LH, Waldherr R, Jayne DR, Rasmussen N, Bruijn JA, Hagen EC; European Vasculitis Study Group (EUVAS): Determinants of outcome in ANCA-associated glomerulonephritis: A prospective clinico-histopathological analysis of 96 patients. Kidney Int 62: 1732–1742, 2002.
11. Roberts IS, Cook HT, Troyanov S, Alpers CE, Amore A, Barratt J, Berthoux F, Bonsib S, Bruijn JA, Cattran DC, Coppo R, D’Agati V, D’Amico G, Emancipator S, Emma F, Feehally J, Ferrario F, Fervenza FC, Florquin S, Fogo A, Geddes CC, Groene HJ, Haas M, Herzenberg AM, Hill PA, Hogg RJ, Hsu SI, Jennette JC, Joh K, Julian BA, Kawamura T, Lai FM, Li LS, Li PK, Liu ZH, Mackinnon B, Mezzano S, Schena FP, Tomino Y, Walker PD, Wang H, Weening JJ, Yoshikawa N, Zhang H; Working Group of the International IgA Nephropathy Network and the Renal Pathology Society: The Oxford classification of IgA nephropathy: Pathology definitions, correlations, and reproducibility. Kidney Int 76: 546–556, 2009.
12. Herzenberg AM, Fogo AB, Reich HN, Troyanov S, Bavbek N, Massat AE, Hunley TE, Hladunewich MA, Julian BA, Fervenza FC, Cattran DC: Validation of the Oxford classification of IgA nephropathy. Kidney Int 80: 310–317, 2011.
13. Shima Y, Nakanishi K, Hama T, Mukaiyama H, Togawa H, Hashimura Y, Kaito H, SakoM, Iijima K, YoshikawaN: Validity of the Oxford classification of IgA nephropathy in children. Pediatr Nephrol 27: 783–792, 2012.
14. Le W, Zeng CH, Liu Z, Liu D, Yang Q, Lin RX, Xia ZK, Fan ZM, Zhu G, Wu Y, Xu H, Zhai Y, Ding Y, Yang X, Liang S, Chen H, Xu F, Huang Q, Shen H, Wang J, Fogo AB, Liu ZH: Validation of the Oxford classification of IgA nephropathy for pediatric patients from China. BMC Nephrol 13: 158, 2012.
15. Coppo R, Troyanov S, Camilla R, Hogg RJ, Cattran DC, Cook HT, Feehally J, Roberts IS, Amore A, Alpers CE, Barratt J, Berthoux F, Bonsib S, Bruijn JA, D’Agati V, D’Amico G, Emancipator SN, Emma F, Ferrario F, Fervenza FC, Florquin S, Fogo AB, Geddes CC, Groene HJ, Haas M, Herzenberg AM, Hill PA, Hsu SI, Jennette JC, Joh K, Julian BA, Kawamura T, Lai FM, Li LS, Li PK, Liu ZH, Mezzano S, Schena FP, Tomino Y, Walker PD, Wang H, Weening JJ, Yoshikawa N, Zhang H; Working Group of the International IgA Nephropathy Network and the Renal Pathology Society: The Oxford IgA nephropathy clinicopathological classification is valid for children as well as adults. Kidney Int 77: 921–927, 2010.
16. Ozen S, Ruperto N, Dillon MJ, Bagga A, Barron K, Davin JC, Kawasaki T, Lindsley C, Petty RE, Prieur AM, Ravelli A, Woo P: EULAR/PReS endorsed consensus criteria for the classification of childhood vasculitides. Ann Rheum Dis 65: 936–941, 2006.
17. Schwartz GJ, Muñoz A, Schneider MF, Mak RH, Kaskel F, Warady BA, Furth SL: New equations to estimate GFR in children with CKD. J Am Soc Nephrol 20: 629–637, 2009.
18. Chang DY, Wu LH, Liu G, Chen M, Kallenberg CGM, Zhao MH: Re-evaluation of the histopathologic classification of ANCAassociated glomerulonephritis: A study of 121 patients in a single center. Nephrol Dial Transplant 27: 2343–2349, 2012.
19. Muso E, Endo T, Itabashi M, Kakita H, Iwasaki Y, Tateishi Y, Komiya T, Ihara T, Yumura W, Sugiyama T, Joh K, Suzuki K: Evaluation of the newly proposed simplified histological classification in Japanese cohorts of myeloperoxidase-anti-neutrophil cytoplasmic antibody-associated glomerulonephritis in comparisonwith other Asian and European cohorts. Clin Exp Nephrol 17: 659–662, 2013.
20. Hilhorst M, Wilde B, van Paassen P, Winkens B, van Breda Vriesman P, Cohen Tervaert JW; Limburg Renal Registry: Improved outcome in anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis: A 30-year follow-up study. Nephrol Dial Transplant 28: 373–379, 2013.
21. Togashi M, Komatsuda A, Nara M, Omokawa A, Okuyama S, Sawada K, Wakui H: Validation of the 2010 histopathological classification of ANCA-associated glomerulonephritis in a Japanese single-center cohort [published online ahead of print April 12, 2013]. Mod Rheumatol doi: 10.1007/s10165-013- 0877-0.
22. Renaudineau Y, Le Meur Y: Renal involvement in Wegener’s granulomatosis. Clin Rev Allergy Immunol 35: 22–29, 2008.
23. Bajema IM, Hagen EC, Hermans J, Noël LH, Waldherr R, Ferrario F, Van Der Woude FJ, Bruijn JA: Kidney biopsy as a predictor for renal outcome in ANCA-associated necrotizing glomerulonephritis. Kidney Int 56: 1751–1758, 1999.
24. Hauer HA, Bajema IM, van Houwelingen HC, Ferrario F, Noe¨ l LH, Waldherr R, Jayne DR, Rasmussen N, Bruijn JA, Hagen EC; European Vasculitis Study Group (EUVAS): Renal histology in ANCA-associated vasculitis: differences between diagnostic and serologic subgroups. Kidney Int 61: 80–89, 2002.
25. Berden AE, Jones RB, Erasmus DD, Walsh M, Noël LH, Ferrario F, Waldherr R, Bruijn JA, Jayne DR, Bajema IM; European Vasculitis Society: Tubular lesions predict renal outcome in antineutrophil cytoplasmic antibody-associated glomerulonephritis after rituximab therapy. J Am Soc Nephrol 23: 313–321, 2012