메뉴 건너뛰기




Volumn 2, Issue 2, 2015, Pages e75-e81

Rituximab plus standard of care for treatment of primary immune thrombocytopenia: A systematic review and meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; DEXAMETHASONE; IMMUNOGLOBULIN; PREDNISONE; RHESUS D ANTIBODY; RITUXIMAB;

EID: 84923788615     PISSN: None     EISSN: 23523026     Source Type: Journal    
DOI: 10.1016/S2352-3026(15)00003-4     Document Type: Article
Times cited : (106)

References (46)
  • 1
    • 78349306455 scopus 로고    scopus 로고
    • The efficacy of different dose intravenous immunoglobulin in treating acute idiopathic thrombocytopenic purpura: a meta-analysis of 13 randomized controlled trials
    • Qin YH, Zhou TB, Su LN, Lei FY, Zhao YJ, Huang WF The efficacy of different dose intravenous immunoglobulin in treating acute idiopathic thrombocytopenic purpura: a meta-analysis of 13 randomized controlled trials. Blood Coagul Fibrinolysis 2010, 21:713-721.
    • (2010) Blood Coagul Fibrinolysis , vol.21 , pp. 713-721
    • Qin, Y.H.1    Zhou, T.B.2    Su, L.N.3    Lei, F.Y.4    Zhao, Y.J.5    Huang, W.F.6
  • 2
    • 84861083164 scopus 로고    scopus 로고
    • Rhig for the treatment of immune thrombocytopenia: consensus and controversy (CME)
    • Despotovic JM, Lambert MP, Herman JH, et al. Rhig for the treatment of immune thrombocytopenia: consensus and controversy (CME). Transfusion 2012, 52:1126-1136.
    • (2012) Transfusion , vol.52 , pp. 1126-1136
    • Despotovic, J.M.1    Lambert, M.P.2    Herman, J.H.3
  • 3
    • 84876198697 scopus 로고    scopus 로고
    • Long-term treatment with romiplostim in patients with chronic immune thrombocytopenia: safety and efficacy
    • Kuter DJ, Bussel JB, Newland A, et al. Long-term treatment with romiplostim in patients with chronic immune thrombocytopenia: safety and efficacy. Br J Haematol 2013, 161:411-423.
    • (2013) Br J Haematol , vol.161 , pp. 411-423
    • Kuter, D.J.1    Bussel, J.B.2    Newland, A.3
  • 4
    • 84872582501 scopus 로고    scopus 로고
    • Safety and efficacy of eltrombopag for treatment of chronic immune thrombocytopenia: results of the long-term, open-label extend study
    • Saleh MN, Bussel JB, Cheng G, et al. Safety and efficacy of eltrombopag for treatment of chronic immune thrombocytopenia: results of the long-term, open-label extend study. Blood 2013, 121:537-545.
    • (2013) Blood , vol.121 , pp. 537-545
    • Saleh, M.N.1    Bussel, J.B.2    Cheng, G.3
  • 5
    • 79955984501 scopus 로고    scopus 로고
    • The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia
    • Neunert C, Lim W, Crowther M, Cohen A, Solberg L, Crowther MA The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia. Blood 2011, 117:4190-4207.
    • (2011) Blood , vol.117 , pp. 4190-4207
    • Neunert, C.1    Lim, W.2    Crowther, M.3    Cohen, A.4    Solberg, L.5    Crowther, M.A.6
  • 6
    • 7244232710 scopus 로고    scopus 로고
    • Splenectomy for adult patients with idiopathic thrombocytopenic purpura: a systematic review to assess long-term platelet count responses, prediction of response, and surgical complications
    • Kojouri K, Vesely SK, Terrell DR, George JN Splenectomy for adult patients with idiopathic thrombocytopenic purpura: a systematic review to assess long-term platelet count responses, prediction of response, and surgical complications. Blood 2004, 104:2623-2634.
    • (2004) Blood , vol.104 , pp. 2623-2634
    • Kojouri, K.1    Vesely, S.K.2    Terrell, D.R.3    George, J.N.4
  • 7
    • 84911945652 scopus 로고    scopus 로고
    • Understanding why patients with immune thrombocytopenia are deeply divided on splenectomy
    • Wang KK, Charles C, Heddle NM, Arnold E, Molnar L, Arnold DM Understanding why patients with immune thrombocytopenia are deeply divided on splenectomy. Health Expect 2012, 17:809-817.
    • (2012) Health Expect , vol.17 , pp. 809-817
    • Wang, K.K.1    Charles, C.2    Heddle, N.M.3    Arnold, E.4    Molnar, L.5    Arnold, D.M.6
  • 8
    • 84864555317 scopus 로고    scopus 로고
    • How I treat immune thrombocytopenia: the choice between splenectomy or a medical therapy as a second-line treatment
    • Ghanima W, Godeau B, Cines DB, Bussel JB How I treat immune thrombocytopenia: the choice between splenectomy or a medical therapy as a second-line treatment. Blood 2012, 120:960-969.
    • (2012) Blood , vol.120 , pp. 960-969
    • Ghanima, W.1    Godeau, B.2    Cines, D.B.3    Bussel, J.B.4
  • 9
    • 84874984825 scopus 로고    scopus 로고
    • Rituximab for thrombotic thrombocytopenic purpura: Benefit of early administration during acute episodes and use of prophylaxis to prevent relapse
    • Westwood JP, Webster H, McGuckin S, McDonald V, Machin SJ, Scully M Rituximab for thrombotic thrombocytopenic purpura: Benefit of early administration during acute episodes and use of prophylaxis to prevent relapse. J Thromb Haemost 2013, 11:481-490.
    • (2013) J Thromb Haemost , vol.11 , pp. 481-490
    • Westwood, J.P.1    Webster, H.2    McGuckin, S.3    McDonald, V.4    Machin, S.J.5    Scully, M.6
  • 10
    • 80054110272 scopus 로고    scopus 로고
    • Evidence-based focused review of the treatment of idiopathic warm immune hemolytic anemia in adults
    • Crowther M, Chan YL, Garbett IK, Lim W, Vickers MA, Crowther MA Evidence-based focused review of the treatment of idiopathic warm immune hemolytic anemia in adults. Blood 2011, 118:4036-4040.
    • (2011) Blood , vol.118 , pp. 4036-4040
    • Crowther, M.1    Chan, Y.L.2    Garbett, I.K.3    Lim, W.4    Vickers, M.A.5    Crowther, M.A.6
  • 11
    • 33846918681 scopus 로고    scopus 로고
    • Systematic review: efficacy and safety of rituximab for adults with idiopathic thrombocytopenic purpura
    • Arnold DM, Dentali F, Crowther MA, et al. Systematic review: efficacy and safety of rituximab for adults with idiopathic thrombocytopenic purpura. Ann Intern Med 2007, 146:25-33.
    • (2007) Ann Intern Med , vol.146 , pp. 25-33
    • Arnold, D.M.1    Dentali, F.2    Crowther, M.A.3
  • 12
    • 84859001212 scopus 로고    scopus 로고
    • The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
    • Higgins JP, Altman DG, Gotzsche PC, et al. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ 2011, 343:d5928.
    • (2011) BMJ , vol.343 , pp. d5928
    • Higgins, J.P.1    Altman, D.G.2    Gotzsche, P.C.3
  • 13
    • 0029914622 scopus 로고    scopus 로고
    • Assessing the quality of reports of randomized clinical trials: is blinding necessary?
    • Jadad AR, Moore RA, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary?. Control Clin Trials 1996, 17:1-12.
    • (1996) Control Clin Trials , vol.17 , pp. 1-12
    • Jadad, A.R.1    Moore, R.A.2    Carroll, D.3
  • 15
    • 0017360990 scopus 로고
    • The measurement of observer agreement for categorical data
    • Landis JR, Koch GG The measurement of observer agreement for categorical data. Biometrics 1977, 33:159-174.
    • (1977) Biometrics , vol.33 , pp. 159-174
    • Landis, J.R.1    Koch, G.G.2
  • 16
    • 84877594229 scopus 로고    scopus 로고
    • Rituximab and dexamethasone vs dexamethasone monotherapy in newly diagnosed patients with primary immune thrombocytopenia
    • Gudbrandsdottir S, Birgens HS, Frederiksen H, et al. Rituximab and dexamethasone vs dexamethasone monotherapy in newly diagnosed patients with primary immune thrombocytopenia. Blood 2013, 121:1976-1981.
    • (2013) Blood , vol.121 , pp. 1976-1981
    • Gudbrandsdottir, S.1    Birgens, H.S.2    Frederiksen, H.3
  • 17
    • 77950974675 scopus 로고    scopus 로고
    • Dexamethasone plus rituximab yields higher sustained response rates than dexamethasone monotherapy in adults with primary immune thrombocytopenia
    • Zaja F, Baccarani M, Mazza P, et al. Dexamethasone plus rituximab yields higher sustained response rates than dexamethasone monotherapy in adults with primary immune thrombocytopenia. Blood 2010, 115:2755-2762.
    • (2010) Blood , vol.115 , pp. 2755-2762
    • Zaja, F.1    Baccarani, M.2    Mazza, P.3
  • 18
    • 84863116186 scopus 로고    scopus 로고
    • A pilot randomized trial of adjuvant rituximab or placebo for nonsplenectomized patients with immune thrombocytopenia
    • Arnold DM, Heddle NM, Carruthers J, et al. A pilot randomized trial of adjuvant rituximab or placebo for nonsplenectomized patients with immune thrombocytopenia. Blood 2012, 119:1356-1362.
    • (2012) Blood , vol.119 , pp. 1356-1362
    • Arnold, D.M.1    Heddle, N.M.2    Carruthers, J.3
  • 19
    • 78751580375 scopus 로고    scopus 로고
    • Low-dose rituximab combined with short-term glucocorticoids up-regulates Treg cell levels in patients with immune thrombocytopenia
    • Li Z, Mou W, Lu G, et al. Low-dose rituximab combined with short-term glucocorticoids up-regulates Treg cell levels in patients with immune thrombocytopenia. Int J Hematol 2011, 93:91-98.
    • (2011) Int J Hematol , vol.93 , pp. 91-98
    • Li, Z.1    Mou, W.2    Lu, G.3
  • 20
    • 84933279873 scopus 로고    scopus 로고
    • Rituximab as second-line treatment for adult immune thrombocytopenia (the RITP trial): a multicentre, randomised, double-blind, placebo-controlled trial
    • published online Feb 5.
    • Ghanima W, Khelif A, Waage A, et al. Rituximab as second-line treatment for adult immune thrombocytopenia (the RITP trial): a multicentre, randomised, double-blind, placebo-controlled trial. Lancet 2015, published online Feb 5. http://dx.doi.org/10.1016/S0140-6736(14)61495-1.
    • (2015) Lancet
    • Ghanima, W.1    Khelif, A.2    Waage, A.3
  • 21
    • 21244451036 scopus 로고    scopus 로고
    • Assessment of a therapeutic strategy for adults with severe autoimmune thrombocytopenic purpura based on a bleeding score rather than platelet count
    • Khellaf M, Michel M, Schaeffer A, Bierling P, Godeau B Assessment of a therapeutic strategy for adults with severe autoimmune thrombocytopenic purpura based on a bleeding score rather than platelet count. Haematologica 2005, 90:829-832.
    • (2005) Haematologica , vol.90 , pp. 829-832
    • Khellaf, M.1    Michel, M.2    Schaeffer, A.3    Bierling, P.4    Godeau, B.5
  • 22
    • 34250886503 scopus 로고    scopus 로고
    • The immune thrombocytopenic purpura (ITP) bleeding score: assessment of bleeding in patients with ITP
    • Page LK, Psaila B, Provan D, et al. The immune thrombocytopenic purpura (ITP) bleeding score: assessment of bleeding in patients with ITP. Br J Haematol 2007, 138:245-248.
    • (2007) Br J Haematol , vol.138 , pp. 245-248
    • Page, L.K.1    Psaila, B.2    Provan, D.3
  • 23
    • 84923793347 scopus 로고    scopus 로고
    • Severe bleeding events in adults and children with primary immune thrombocytopenia: a systematic review
    • published online Dec 12.
    • Neunert C, Noroozi N, Norman G, et al. Severe bleeding events in adults and children with primary immune thrombocytopenia: a systematic review. J Thromb Haemost 2014, published online Dec 12. 10.1111/jth.12813.
    • (2014) J Thromb Haemost
    • Neunert, C.1    Noroozi, N.2    Norman, G.3
  • 24
    • 84863826816 scopus 로고    scopus 로고
    • Rituximab before splenectomy in adults with primary idiopathic thrombocytopenic purpura: a meta-analysis
    • Auger S, Duny Y, Rossi JF, Quittet P Rituximab before splenectomy in adults with primary idiopathic thrombocytopenic purpura: a meta-analysis. Br J Haematol 2012, 158:386-398.
    • (2012) Br J Haematol , vol.158 , pp. 386-398
    • Auger, S.1    Duny, Y.2    Rossi, J.F.3    Quittet, P.4
  • 25
    • 84861616693 scopus 로고    scopus 로고
    • Rituximab for children with immune thrombocytopenia: a systematic review
    • Liang Y, Zhang L, Gao J, Hu D, Ai Y Rituximab for children with immune thrombocytopenia: a systematic review. PLoS One 2012, 7:e36698.
    • (2012) PLoS One , vol.7 , pp. e36698
    • Liang, Y.1    Zhang, L.2    Gao, J.3    Hu, D.4    Ai, Y.5
  • 26
    • 50949104584 scopus 로고    scopus 로고
    • Rituximab efficacy and safety in adult splenectomy candidates with chronic immune thrombocytopenic purpura: results of a prospective multicenter phase 2 study
    • Godeau B, Porcher R, Fain O, et al. Rituximab efficacy and safety in adult splenectomy candidates with chronic immune thrombocytopenic purpura: results of a prospective multicenter phase 2 study. Blood 2008, 112:999-1004.
    • (2008) Blood , vol.112 , pp. 999-1004
    • Godeau, B.1    Porcher, R.2    Fain, O.3
  • 27
    • 84862739912 scopus 로고    scopus 로고
    • Outcomes 5 years after response to rituximab therapy in children and adults with immune thrombocytopenia
    • Patel VL, Mahevas M, Lee SY, et al. Outcomes 5 years after response to rituximab therapy in children and adults with immune thrombocytopenia. Blood 2012, 119:5989-5995.
    • (2012) Blood , vol.119 , pp. 5989-5995
    • Patel, V.L.1    Mahevas, M.2    Lee, S.Y.3
  • 28
    • 84865359222 scopus 로고    scopus 로고
    • Long-term follow-up analysis after rituximab salvage therapy in adult patients with immune thrombocytopenia
    • Zaja F, Volpetti S, Chiozzotto M, et al. Long-term follow-up analysis after rituximab salvage therapy in adult patients with immune thrombocytopenia. Am J Hematol 2012, 87:886-889.
    • (2012) Am J Hematol , vol.87 , pp. 886-889
    • Zaja, F.1    Volpetti, S.2    Chiozzotto, M.3
  • 29
    • 84903579618 scopus 로고    scopus 로고
    • Rituximab and three dexamethasone cycles provide responses similar to splenectomy in women and those with immune thrombocytopenia of less than two years duration
    • Bussel JB, Lee CS, Seery C, et al. Rituximab and three dexamethasone cycles provide responses similar to splenectomy in women and those with immune thrombocytopenia of less than two years duration. Haematologica 2014, 99:1264-1271.
    • (2014) Haematologica , vol.99 , pp. 1264-1271
    • Bussel, J.B.1    Lee, C.S.2    Seery, C.3
  • 30
    • 0024517811 scopus 로고
    • Platelet survival and turnover: important factors in predicting response to splenectomy in immune thrombocytopenic purpura
    • Siegel RS, Rae JL, Barth S, et al. Platelet survival and turnover: important factors in predicting response to splenectomy in immune thrombocytopenic purpura. Am J Hematol 1989, 30:206-212.
    • (1989) Am J Hematol , vol.30 , pp. 206-212
    • Siegel, R.S.1    Rae, J.L.2    Barth, S.3
  • 31
    • 84873828057 scopus 로고    scopus 로고
    • B cell depletion in immune thrombocytopenia reveals splenic long-lived plasma cells
    • Mahevas M, Patin P, Huetz F, et al. B cell depletion in immune thrombocytopenia reveals splenic long-lived plasma cells. J Clin Invest 2013, 123:432-442.
    • (2013) J Clin Invest , vol.123 , pp. 432-442
    • Mahevas, M.1    Patin, P.2    Huetz, F.3
  • 32
    • 35548960551 scopus 로고    scopus 로고
    • Response to B-cell depleting therapy with rituximab reverts the abnormalities of T-cell subsets in patients with idiopathic thrombocytopenic purpura
    • Stasi R, Del Poeta G, Stipa E, et al. Response to B-cell depleting therapy with rituximab reverts the abnormalities of T-cell subsets in patients with idiopathic thrombocytopenic purpura. Blood 2007, 110:2924-2930.
    • (2007) Blood , vol.110 , pp. 2924-2930
    • Stasi, R.1    Del Poeta, G.2    Stipa, E.3
  • 33
    • 84904579644 scopus 로고    scopus 로고
    • Clinical practice. Care of the asplenic patient
    • Rubin LG, Schaffner W Clinical practice. Care of the asplenic patient. N Engl J Med 2014, 371:349-356.
    • (2014) N Engl J Med , vol.371 , pp. 349-356
    • Rubin, L.G.1    Schaffner, W.2
  • 34
    • 84919587816 scopus 로고
    • Splenectomy and subsequent mortality in veterans of the 1939-45 war
    • Robinette CD, Fraumeni JF Splenectomy and subsequent mortality in veterans of the 1939-45 war. Lancet 1977, 2:127-129.
    • (1977) Lancet , vol.2 , pp. 127-129
    • Robinette, C.D.1    Fraumeni, J.F.2
  • 35
    • 77954502194 scopus 로고    scopus 로고
    • Risk of venous thromboembolism in splenectomized patients compared with the general population and appendectomized patients: a 10-year nationwide cohort study
    • Thomsen RW, Schoonen WM, Farkas DK, Riis A, Fryzek JP, Sorensen HT Risk of venous thromboembolism in splenectomized patients compared with the general population and appendectomized patients: a 10-year nationwide cohort study. J Thromb Haemost 2010, 8:1413-1416.
    • (2010) J Thromb Haemost , vol.8 , pp. 1413-1416
    • Thomsen, R.W.1    Schoonen, W.M.2    Farkas, D.K.3    Riis, A.4    Fryzek, J.P.5    Sorensen, H.T.6
  • 36
    • 47649096922 scopus 로고    scopus 로고
    • Delayed adverse vascular events after splenectomy in hereditary spherocytosis
    • Schilling RF, Gangnon RE, Traver MI Delayed adverse vascular events after splenectomy in hereditary spherocytosis. J Thromb Haemost 2008, 6:1289-1295.
    • (2008) J Thromb Haemost , vol.6 , pp. 1289-1295
    • Schilling, R.F.1    Gangnon, R.E.2    Traver, M.I.3
  • 37
    • 84886249145 scopus 로고    scopus 로고
    • FDA: Increased HBV reactivation risk with ofatumumab or rituximab
    • Mitka M FDA: Increased HBV reactivation risk with ofatumumab or rituximab. JAMA 2013, 310:1664.
    • (2013) JAMA , vol.310 , pp. 1664
    • Mitka, M.1
  • 38
    • 66549130454 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the research on adverse drug events and reports project
    • Carson KR, Evens AM, Richey EA, et al. Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the research on adverse drug events and reports project. Blood 2009, 113:4834-4840.
    • (2009) Blood , vol.113 , pp. 4834-4840
    • Carson, K.R.1    Evens, A.M.2    Richey, E.A.3
  • 39
    • 84892872044 scopus 로고    scopus 로고
    • Rituximab versus splenectomy in persistent or chronic adult primary immune thrombocytopenia: an adjusted comparison of mortality and morbidity
    • Moulis G, Sailler L, Sommet A, Lapeyre-Mestre M, Derumeaux H, Adoue D Rituximab versus splenectomy in persistent or chronic adult primary immune thrombocytopenia: an adjusted comparison of mortality and morbidity. Am J Hematol 2014, 89:41-46.
    • (2014) Am J Hematol , vol.89 , pp. 41-46
    • Moulis, G.1    Sailler, L.2    Sommet, A.3    Lapeyre-Mestre, M.4    Derumeaux, H.5    Adoue, D.6
  • 40
    • 64049085194 scopus 로고    scopus 로고
    • Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group
    • Rodeghiero F, Stasi R, Gernsheimer T, et al. Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group. Blood 2009, 113:2386-2393.
    • (2009) Blood , vol.113 , pp. 2386-2393
    • Rodeghiero, F.1    Stasi, R.2    Gernsheimer, T.3
  • 41
    • 84878117957 scopus 로고    scopus 로고
    • High response rate to low-dose rituximab plus high-dose dexamethasone as frontline therapy in adult patients with primary immune thrombocytopenia
    • Gomez-Almaguer D, Tarin-Arzaga L, Moreno-Jaime B, et al. High response rate to low-dose rituximab plus high-dose dexamethasone as frontline therapy in adult patients with primary immune thrombocytopenia. Eur J Haematol 2013, 90:494-500.
    • (2013) Eur J Haematol , vol.90 , pp. 494-500
    • Gomez-Almaguer, D.1    Tarin-Arzaga, L.2    Moreno-Jaime, B.3
  • 42
    • 37049016216 scopus 로고    scopus 로고
    • Activity and safety profile of low-dose rituximab for the treatment of autoimmune cytopenias in adults
    • Provan D, Butler T, Evangelista ML, Amadori S, Newland AC, Stasi R Activity and safety profile of low-dose rituximab for the treatment of autoimmune cytopenias in adults. Haematologica 2007, 92:1695-1698.
    • (2007) Haematologica , vol.92 , pp. 1695-1698
    • Provan, D.1    Butler, T.2    Evangelista, M.L.3    Amadori, S.4    Newland, A.C.5    Stasi, R.6
  • 43
    • 77956973924 scopus 로고    scopus 로고
    • Low-dose rituximab in adult patients with primary immune thrombocytopenia
    • Zaja F, Vianelli N, Volpetti S, et al. Low-dose rituximab in adult patients with primary immune thrombocytopenia. Eur J Haematol 2010, 85:329-334.
    • (2010) Eur J Haematol , vol.85 , pp. 329-334
    • Zaja, F.1    Vianelli, N.2    Volpetti, S.3
  • 44
    • 44949126978 scopus 로고    scopus 로고
    • Lower dose rituximab is active in adults patients with idiopathic thrombocytopenic purpura
    • Zaja F, Battista ML, Pirrotta MT, et al. Lower dose rituximab is active in adults patients with idiopathic thrombocytopenic purpura. Haematologica 2008, 93:930-933.
    • (2008) Haematologica , vol.93 , pp. 930-933
    • Zaja, F.1    Battista, M.L.2    Pirrotta, M.T.3
  • 45
    • 84883493782 scopus 로고    scopus 로고
    • Clinical efficacy of lower dose rituximab for chronic refractory immune thrombocytopenic purpura
    • Li Y, Wang XM, Mao M, et al. Clinical efficacy of lower dose rituximab for chronic refractory immune thrombocytopenic purpura. Chin J Hematol 2012, 33:204-206.
    • (2012) Chin J Hematol , vol.33 , pp. 204-206
    • Li, Y.1    Wang, X.M.2    Mao, M.3
  • 46
    • 84908393112 scopus 로고    scopus 로고
    • Efficacy and safety of low-dose rituximab combined with different dosage of glucocorticoids for immune thrombocytopenia
    • Xing WW, Li ZY, Yan ZL, et al. Efficacy and safety of low-dose rituximab combined with different dosage of glucocorticoids for immune thrombocytopenia. Chin J Hematol 2013, 34:409-412.
    • (2013) Chin J Hematol , vol.34 , pp. 409-412
    • Xing, W.W.1    Li, Z.Y.2    Yan, Z.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.