Role of sphingosine-1-phosphate receptor 1 and sphingosine-1-phosphate receptor 2 in hyperglycemia-induced endothelial cell dysfunction

International Journal of Molecular Medicine

Volumn 35, Issue 4, 2015, Pages 1103-1108

  Chen, Shuhua ^a   Yang, Jie ^a   Xiang, Hong ^a   Chen, Wei ^a   Zhong, Hua ^a   Yang, Guoping ^a   Fang, Ting ^a   Deng, Hao ^a   Yuan, Hong ^a   Chen, Alex F ^a,b   Lu, Hongwei ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Endothelial cells; Hyperglycemia; Oxidative stress; Sphingosine 1 phosphate receptor 1; Sphingosine 1 phosphate receptor 2

Indexed keywords

ADENOVIRUS VECTOR; GLUCOSE; MATRIGEL; MESSENGER RNA; NITRATE REDUCTASE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 1; SPHINGOSINE 1 PHOSPHATE RECEPTOR 2; UNCLASSIFIED DRUG; S1PR1 PROTEIN, HUMAN; S1PR2 PROTEIN, HUMAN;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENDOTHELIAL CELL DYSFUNCTION; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; FLOW CYTOMETRY; GENE OVEREXPRESSION; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; MORPHOGENESIS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSIENT TRANSFECTION; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

CELLS, CULTURED; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; GLUCOSE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYPERGLYCEMIA; NITRIC OXIDE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RECEPTORS, LYSOSPHINGOLIPID;

EID: 84923700005     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2015.2100     Document Type: Article

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