The opposing forces of the intestinal microbiome and the emerging pathobiome

Surgical Clinics of North America

Volumn 94, Issue 6, 2014, Pages 1151-1161

  Defazio, Jennifer ^a   Fleming, Irma D ^a   Shakhsheer, Baddr ^a   Zaborina, Olga ^a   Alverdy, John C ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Anastomotic leak; Bacteria; Infection; Metabolomics; Microbiome; Proteomics; Sepsis

Indexed keywords

ANASTOMOSIS LEAKAGE; ANTIBIOTIC RESISTANCE; COLORECTAL SURGERY; GENOMICS; GUT DERIVED SEPSIS; HUMAN; INCIDENCE; INTESTINE FLORA; INTESTINE PREPARATION; METABOLOMICS; METAGENOMICS; MICROBIOME; NEXT GENERATION SEQUENCING; PRIORITY JOURNAL; PROTEOMICS; REVIEW; SEPSIS; SURGICAL INFECTION; ADVERSE EFFECTS; ANASTOMOTIC LEAK; ANTIBIOTIC PROPHYLAXIS; DRUG EFFECTS; GENETICS; INTESTINE; MICROBIOLOGY; MICROFLORA; POSTOPERATIVE COMPLICATIONS; PREOPERATIVE CARE; PROCEDURES; SURGERY; SURGICAL WOUND INFECTION;

LAXATIVE;

ANASTOMOTIC LEAK; ANTIBIOTIC PROPHYLAXIS; CATHARTICS; DRUG RESISTANCE, BACTERIAL; HUMANS; INTESTINES; METAGENOMICS; MICROBIOTA; POSTOPERATIVE COMPLICATIONS; PREOPERATIVE CARE; PROTEOMICS; SEPSIS; SURGICAL WOUND INFECTION;

EID: 84923658654     PISSN: 00396109     EISSN: 15583171     Source Type: Journal    
DOI: 10.1016/j.suc.2014.08.002     Document Type: Review

References (49)

1. Morowitz M.J., Babrowski T., Carlisle E.M., et al. The human microbiome and surgical disease. Ann Surg 2011, 253(6):1094-1101. 10.1097/SLA.0b013e31821175d7.
2. Viaud S., Saccheri F., Mignot G., et al. The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide. Science 2013, 342(6161):971-976. 10.1126/science.1240537.
3. Iida N., Dzutsev A., Stewart C.A., et al. Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment. Science 2013, 342(6161):967-970. 10.1126/science.1240527.
4. Mangram A.J., Horan T.C., Pearson M.L., et al. Guideline for prevention of surgical sit infection, 1999. Surg Outcomes 1999, 27(2):98-134.
5. Alexander J. The contributions of infection control to a century of surgical progress. Ann Surg 1985, 201:423-428.
6. Wangensteen O., Wandensteen S., Klinger C. Surgical cleanliness, hospital salubrity, and surgical statistics, historically considered. Surgery 1972, 71:477-493.
7. Burke J. The effective period of preventive antibiotic action in experimental incision and dermal lesions. Surgery 1960, 50:161-168.
8. Bernard H., Cole W. The prophylaxis of surgical infection: the effect of prophylactic antimicrobial drugs on the incidence of infection following potentially contaminated operations. Surgery 2014, 56:151-159.
9. Nichols R. Surgery annual. Nyhus LM, editor. Vol 13. New York: Appleton-Century-Crofts; 1981.
10. Antimicrobial prophylaxis in surgery. Med Lett Drugs Ther 2014, 41:75-80.
11. Guenaga K.F., Matos D., Wille-Jorgensen P. Mechanical bowel preparation for elective colorectal surgery. Cochrane Database Syst Rev 2009, (1):CD001544.
12. Contant C.M., Hop W.C., van Sant H.P., et al. Mechanical bowel preparation for elective colorectal surgery: a multicentre randomised trial. The Lancet 2007, 370(9605):2112-2117. 10.1016/S0140-6736(07)61905-9.
13. Platell C., Hall J. What is the role of mechanical bowel preparation in patients undergoing colorectal surgery. Dis Colon Rectum 1998, 41(7):882-883.
14. Slim K., Vicaut E., Panis Y., et al. Meta-analysis of randomized clinical trials of colorectal surgery with or without mechanical bowel preparation. Br J Surg 2004, 91(9):1125-1130. 10.1002/bjs.4651.
15. van den Bogaard A., Weidema W., van Boven C., et al. Recolonization and colonization resistance of the large bowel after three methods of preoperative preparation of the gastrointestinal tract for elective colorectal surgery. JHyg 1986, 97:49-59.
16. Jung B., Matthiessen P., Smedh K., et al. Mechanical bowel preparation does not affect the intramucosal bacterial colony count. Int J Colorectal Dis 2010, 25(4):439-442. 10.1007/s00384-009-0863-3.
17. Arabi Y., Dimock F., Burdon D., et al. Influence of bowel preparation and antimicrobials on colonic microflora. Br J Surg 1978, 65(8):555-558.
18. Clarke J., Condon R., Barlett J. Preoperative oral antibiotics reduce septic complications of colon operations: results of prospective, randomized, double-blind clinical study. Ann Surg 1977, 186(3):251-259.
19. Blumetti J., Luu M., Sarosi G., et al. Surgical site infections after colorectal surgery: do risk factors vary depending on the type of infection considered?. Surgery 2007, 142(5):704-711. 10.1016/j.surg.2007.05.012.
20. Khan A.A., Wheeler J.M., Cunningham C., et al. The management and outcome of anastomotic leaks in colorectal surgery. Colorectal Dis 2008, 10(6):587-592. 10.1111/j.1463-1318.2007.01417.x.
21. Tytherleigh M.G., Bokey L., Chapuis P.H., et al. Is a minor clinical anastomotic leak clinically significant after resection of colorectal cancer?. JAm Coll Surg 2007, 205(5):648-653. 10.1016/j.jamcollsurg.2007.05.031.
22. Kirkland K.B., Meriwether R.A., MacKenzie W.R., et al. Clinician judgment as a tool for targeting HIV counseling and testing in North Carolina state mental hospitals, 1994. AIDS Patient Care STDS 1999, 13(8):473-479.
23. Sears C.L. Adynamic partnership: celebrating our gut flora. Anaerobe 2005, 11(5):247-251. 10.1016/j.anaerobe.2005.05.001.
24. Turnbaugh P.J., Ley R.E., Mahowald M.A., et al. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 2006, 444(7122):1027-1131. 10.1038/nature05414.
25. das U.N. Obesity: genes, brain, gut, and environment. Nutrition 2010, 26(5):459-473. 10.1016/j.nut.2009.09.020.
26. Backhed F., Manchester J.K., Semenkovich C.F., et al. Mechanisms underlying the resistance to diet-induced obesity in germ-free mice. Proc Natl Acad Sci USA 2007, 104(3):979-984. 10.1073/pnas.0605374104.
27. Backhed F., Ding H., Wang T., et al. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci USA 2004, 101(44):15718-15723. 10.1073/pnas.0407076101.
28. Wostmann B., Larkin C., Moriarty A., et al. Dietary intake, energy metabolism, and excretory losses of adult male germfree Wistar rats. Lab Anim Sci 1983, 33(1):46-50.
29. Ley R., Turnbaugh P.J., Klein S., et al. Microbial ecology: human gut microbes associated with obesity. Nature 2006, 444(21):1-2. 10.1038/nature4441021a.
30. Zhang H., DiBaise J.K., Zuccolo A., et al. Human gut microbiota in obesity and after gastric bypass. Proc Natl Acad Sci USA 2009, 106(7):2365-2370. 10.1073/pnas.0812600106.
31. Vaishnava S., Behrendt C., Ismail A., et al. Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc Natl Acad Sci USA 2008, 105:20858-20863.
32. Littman D., Pamer E. Role of the commensal microbiota in normal and pathogenic host immune responses. Cell Host Microbe 2011, 10(4):311-323. 10.1016/j.chom.2011.10.004.
33. Peterson J., Garges S., Giovanni M., et al. The NIH human microbiome project. Genome Res 2009, 19(12):2317-2323. 10.1101/gr.096651.109.
34. Zoetendal E.G., Rajilic-Stojanovic M., de Vos W.M. High-throughput diversity and functionality analysis of the gastrointestinal tract microbiota. Gut 2008, 57(11):1605-1615. 10.1136/gut.2007.133603.
35. Gosalbes M.J., Durbán A., Pignatelli M., et al. Metatranscriptomic approach to analyze the functional human gut microbiota. PLoS One 2011, 6(3):e17447. 10.1371/journal.pone.0017447.
36. Jansson J., Willing B., Lucio M., et al. Metabolomics reveals metabolic biomarkers of Crohn's disease. PLoS One 2009, 4(7):e6386. 10.1371/journal.pone.0006386.
37. Kolmeder C.A., Vos W.M., de Vos W.M. Metaproteomics of our microbiome - developing insight in function and activity in man and model systems. JProteomics 2014, 97:3-16. 10.1016/j.jprot.2013.05.018.
38. Cohn I., Rives J. Antibiotic protection of colon anastomosis. Ann Surg 1955, 141(5):707-717.
39. Cohen S., Cornell C., Collins M., et al. Healing of ischemic colonic anastomoses in the rat: role of antibiotic preparation. Surgery 1985, 97(4):443-446.
40. Shimizu K., Ogura H., Asahara T., et al. Probiotic symbiotic therapy for treating critically ill patients from a gut microbiota perspective. Dig Dis Sci 2012, 58:23-32.
41. Jones R. Microbial etiologies of hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia. Clin Infect Dis 2010, 51(Suppl 1):S81-S87.
42. Fenandez-Guerrero M., Verdejo C., Azofra J., et al. Hospital-acquired infectious endocarditis not associated with cardiac surgery: an emerging problem. Clin Infect Dis 1995, 20:16-23.
43. Hussein K., Raz-Pasteur A., Finkelztein R., et al. Impact of carbapenem resistance on the outcome of patients' hospital acquired bacteraemia caused by Klebsiella pneumoniae. JHosp Infect 2013, 83:307-313.
44. Zaborin A., Defazio J.R., Kade M., et al. Phosphate-containing polyethylene glycol polymers prevent lethal sepsis by multidrug-resistant pathogens. Antimicrobial Agents Chemother 2014, 58(2):966-977. 10.1128/AAC.02183-13.
45. Nhien Y.S., Kaloostian C., Abbas M.A., et al. The surgical care improvement project (SCIP) initiative to reduce infection in elective colorectal surgery: which performance measures affect outcome?. Am Surg 2008, 74(10):1012-1016.
46. Thompson K.M., Oldenburg W.A., Deschamps C., et al. Chasing zero. Ann Surg 2011, 254(3):430-437. 10.1097/SLA.0b013e31822cc0ad.
47. Kardas P., Devine S., Golembesky A., et al. Asystematic review and meta-analysis of misuse of antibiotic therapies in the community. Int J Antimicrob Agents 2005, 26(2):106-113. 10.1016/j.ijantimicag.2005.04.017.
48. Falagas M., Barefoot L., Griffith J. Risk factors leading to clinical failure in the treatment of intra-abdominal or skin/soft tissue infections. Eur J Clin Microbiol Infect Dis 1996, 15(12):913-921.
49. Eagye K.J., Kim A., Laohavaleeson S., et al. Surgical site infections: does inadequate antibiotic therapy affect patient outcomes?. Surg Infect (Larchmt) 2009, 10(4):323-331. 10.1089/sur.2008.053.