Clinical analysis of fever of unknown origin in children: A 10-year experience in a northern Taiwan medical center

Journal of Microbiology, Immunology and Infection

Volumn 50, Issue 1, 2017, Pages 40-45

  Cho, Ching Yi ^a   Lai, Chou Cheng ^a   Lee, Ming Luen ^a   Hsu, Chien Lun ^a   Chen, Chun Jen ^a   Chang, Lo Yi ^a   Lo, Chiao Wei ^a   Chiang, Sheng Fong ^a   Wu, Keh Gong ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Children; Fever of unknown origin; FUO; Infectious disease; Taiwan

Indexed keywords

IMMUNOMODULATING AGENT; METHYLPREDNISOLONE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ANTIBIOTIC THERAPY; APLASTIC ANEMIA; ARTICLE; CENTRAL NERVOUS SYSTEM INFECTION; CHILD; CHOLANGITIS; CYTOMEGALOVIRUS INFECTION; ENTEROCOCCUS; EPSTEIN BARR VIRUS INFECTION; ESCHERICHIA COLI; FEMALE; FEVER; HEMOPHAGOCYTIC SYNDROME; HISTIOCYTOSIS; HUMAN; JUVENILE RHEUMATOID ARTHRITIS; KLEBSIELLA; LYMPHADENITIS; LYMPHOMA; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MUCOCUTANEOUS LYMPH NODE SYNDROME; MYCOPLASMOSIS; MYELODYSPLASTIC SYNDROME; PATHOGENESIS; PSEUDOMONAS AERUGINOSA; PYREXIA IDIOPATHICA; RETROSPECTIVE STUDY; STEROID THERAPY; SYSTEMIC LUPUS ERYTHEMATOSUS; TAIWAN; UPPER RESPIRATORY TRACT INFECTION; URINARY TRACT INFECTION; COMMUNICABLE DISEASES; FEVER OF UNKNOWN ORIGIN; GENERAL HOSPITAL; INFANT; PATHOLOGY; PRESCHOOL CHILD; PUBLIC HOSPITAL;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; COMMUNICABLE DISEASES; FEMALE; FEVER OF UNKNOWN ORIGIN; HOSPITALS, GENERAL; HOSPITALS, VETERANS; HUMANS; INFANT; MALE; TAIWAN;

EID: 84923620915     PISSN: 16841182     EISSN: 19959133     Source Type: Journal    
DOI: 10.1016/j.jmii.2015.01.001     Document Type: Article

References (28)

1. 1 Petersdorf, R.G., Beeson, P.B., Fever of unexplained origin: report on 100 cases. Medicine (Baltimore) 40 (1961), 1–30.
2. 2 Chow, A., Robinson, J.L., Fever of unknown origin in children: a systematic review. World J Pediatr 7 (2010), 5–10.
3. 3 Chouchane, S., Chouchane, C.H., Ben Meriem, C.H., Selet, B., Hammami, S., Nouri, S., et al. Prolonged fever in children. Retrospective study of 67 cases. Arch Pediatr 11 (2004), 1319–1325.
4. 4 Seashore, C.J., Lohr, J.A., Fever of unknown origin in children. Pediatr Ann 40 (2011), 26–30.
5. 5 Tolan, R.W., Fever of unknown origin: a diagnostic approach to this vexing problem. Clin Pediatr 49 (2010), 207–213.
6. 6 Akpede, G.O., Akenzua, G.I., Management of children with prolonged fever of unknown origin and difficulties in the management of fever of unknown origin in children in developing countries. Paediatr Drugs 3 (2001), 247–262.
7. 7 Jacobs, R.F., Schutze, G.E., Bartonella henselae as a cause of prolonged fever and fever of unknown origin in children. Clin Infect Dis 26 (1998), 80–84.
8. 8 Pasic, S., Minic, A., Djuric, P., Micic, D., Kuzmanovic, Sarjanovic L., et al. Fever of unknown origin in 185 paediatric patients: a single-centre experience. Acta Paediatr 95 (2006), 463–466.
9. 9 Pizzo, P.A., Lovejoy, F.H., Smith, D.H., Prolonged fever in children: review of 100 cases. Pediatrics 55 (1975), 468–473.
10. 10 Cogulu, O., Koturoglu, G., Kurugol, Z., Ozkinay, F., Vardar, F., Pzkinay, C., Evaluation of 80 children with prolonged fever. Pediatr Int 45 (2003), 564–569.
11. 11 Uehara, R., Belay, E.D., Epidemiology of Kawasaki disease in Asia, Europe, and the United States. J Epidemiol 22 (2012), 79–85.
12. 12 Michot, J.-M., Hié, M., Galicier, L., Lambotte, O., Michel, M., Bloch- Queyrat, C., et al. [Hemophagocytic lymphohistiocytosis]. Rev Med Interne 34 (2013), 85–93 [In French].
13. 13 Palazzi, D.L., McClain, K.L., Kaplan, S.L., Hemophagocytic syndrome in children: an important diagnostic consideration in fever of unknown origin. Clin Infect Dis 36 (2003), 306–312.
14. 14 Feigin, R.D., Shearer, W.T., Fever of unknown origin in children. Curr Probl Pediatr 10 (1976), 3–64.
15. 15 Vanderschueren, S., Knockaert, D., Adriaenssens, T., Demey, W., Durnez, A., Blockmans, D., et al. From prolonged febrile illness to fever of unknown origin: the challenge continues. Arch Intern Med 163 (2003), 1033–1041.
16. 16 Bleeker-Rovers, C.P., Vos, F.J., de Kleijn, E.M., Mudde, A.H., Dofferhoff, T.S., Richter, C., et al. A prospective multicenter study on fever of unknown origin: the yield of a structured diagnostic protocol. Medicine (Baltimore) 86 (2007), 26–38.
17. 17 Sur, D.K., Bukont, E.L., Evaluating fever of unidentifiable source in young children. Am Fam Physician 75 (2007), 1805–1811.
18. 18 Steele, R.W., Jones, S.M., Lowe, B.A., Glasier, C.M., Usefulness of scanning procedures for diagnosis of fever of unknown origin in children. J Pediatr 119 (1991), 526–530.
19. 19 Hague, R., Fever of unknown origin–investigation and management. Curr Paediatr 11 (2001), 445–451.
20. 20 Picus, D., Siegel, M.J., Balfe, D.M., Abdominal computed tomography in children with unexplained prolonged fever. J Comput Assist Tomogr 8 (1984), 851–856.
21. 21 Ergül, N., Çermik, T.F., FDG-PET or PET/CT in fever of unknown origin: the diagnostic role of underlying primary disease. Int J Mol Imaging 2011 (2011), 1–8.
22. 22 Bleeker-Rovers, C.P., Vos, F.J., Mudde, A.H., Dofferhoff, A.S., de Geus-Oei, L.F., Fijnders, A.J., et al. A prospective multi-centre study of the value of FDG-PET as part of a structured diagnostic protocol in patients with fever of unknown origin. Eur J Nucl Med Mol Imaging 34 (2007), 694–703.
23. 23 Seam, P., Juweid, M.E., Cheson, B.D., The role of FDG-PET scans in patients with lymphoma. Blood 110 (2007), 3507–3516.
24. 24 Buonomo, C., Treves, S.T., Gallium scanning in children with fever of unknown origin. Pediatr Radiol 23 (1993), 307–310.
25. 25 Mouaket, A.E., el-Ghanim, M.M., Abd-el-Al, Y.K., al-Quod, N., Prolonged unexplained pyrexia: a review of 221 paediatric cases from Kuwait. Infection 18 (1990), 226–229.
26. 26 Arnow, P.M., Flaherty, J.P., Fever of unknown origin. Lancet 350 (1997), 575–580.
27. 27 Miller, L.C., Sisson, B.A., Tucker, L.B., Schaller, J.G., Prolonged fevers of unknown origin in children: patterns of presentation and outcome. J Pediatr 129 (1996), 419–423.
28. 28 Talano, J.A.M., Katz, B.Z., Long-term follow-up of children with fever of unknown origin. Clin Pediatr 39 (2000), 715–717.