-
1
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
PubMed PMID: 17618441; PubMed Central PMCID: PMC1929165.
-
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol (2007) 114(2):97-109. doi: 10.1007/s00401-007-0243-4. PubMed PMID: 17618441; PubMed Central PMCID: PMC1929165.
-
(2007)
Acta Neuropathol
, vol.114
, Issue.2
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
Cavenee, W.K.4
Burger, P.C.5
Jouvet, A.6
-
2
-
-
84875211731
-
Cancer heterogeneity: implications for targeted therapeutics
-
PubMed PMID: 23299535; PubMed Central PMCID: PMC3593543.
-
Fisher R, Pusztai L, Swanton C. Cancer heterogeneity: implications for targeted therapeutics. Br J Cancer (2013) 108(3):479-85. doi: 10.1038/bjc.2012.581. PubMed PMID: 23299535; PubMed Central PMCID: PMC3593543.
-
(2013)
Br J Cancer
, vol.108
, Issue.3
, pp. 479-485
-
-
Fisher, R.1
Pusztai, L.2
Swanton, C.3
-
4
-
-
4944255253
-
Genetic pathways to glioblastoma: a population-based study
-
64/19/6892 [pii]10.1158/0008-5472.CAN-04-1337 PubMed PMID: 15466178. Epub 2004/10/07
-
Ohgaki H, Dessen P, Jourde B, Horstmann S, Nishikawa T, Di Patre PL, et al. Genetic pathways to glioblastoma: a population-based study. Cancer Res (2004) 64(19):6892-9. Epub 2004/10/07. doi: 64/19/6892 [pii]10.1158/0008-5472.CAN-04-1337. PubMed PMID: 15466178.
-
(2004)
Cancer Res
, vol.64
, Issue.19
, pp. 6892-6899
-
-
Ohgaki, H.1
Dessen, P.2
Jourde, B.3
Horstmann, S.4
Nishikawa, T.5
Di Patre, P.L.6
-
5
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
PubMed PMID: 20129251; PubMed Central PMCID: PMC2818769.
-
Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell (2010) 17(1):98-110. doi: 10.1016/j.ccr.2009.12.020. PubMed PMID: 20129251; PubMed Central PMCID: PMC2818769.
-
(2010)
Cancer Cell
, vol.17
, Issue.1
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
Wang, V.4
Qi, Y.5
Wilkerson, M.D.6
-
6
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
PubMed PMID: 16530701.
-
Phillips HS, Kharbanda S, Chen R, Forrest WF, Soriano RH, Wu TD, et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell (2006) 9(3):157-73. doi: 10.1016/j.ccr.2006.02.019. PubMed PMID: 16530701.
-
(2006)
Cancer Cell
, vol.9
, Issue.3
, pp. 157-173
-
-
Phillips, H.S.1
Kharbanda, S.2
Chen, R.3
Forrest, W.F.4
Soriano, R.H.5
Wu, T.D.6
-
7
-
-
84885074034
-
The Somatic Genomic Landscape of Glioblastoma
-
PubMed PMID: WOS:000325719800021.
-
Brennan CW, Verhaak RGW, McKenna A, Campos B, Noushmehr H, Salama SR, et al. The Somatic Genomic Landscape of Glioblastoma. Cell (2013) 155(2):462-77. doi: DOI 10.1016/j.cell.2013.09.034. PubMed PMID: WOS:000325719800021.
-
(2013)
Cell
, vol.155
, Issue.2
, pp. 462-477
-
-
Brennan, C.W.1
Verhaak, R.G.W.2
McKenna, A.3
Campos, B.4
Noushmehr, H.5
Salama, S.R.6
-
8
-
-
77952108366
-
Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
-
PubMed PMID: 20399149; PubMed Central PMCID: PMC2872684.
-
Noushmehr H, Weisenberger DJ, Diefes K, Phillips HS, Pujara K, Berman BP, et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell (2010) 17(5):510-22. doi: 10.1016/j.ccr.2010.03.017. PubMed PMID: 20399149; PubMed Central PMCID: PMC2872684.
-
(2010)
Cancer Cell
, vol.17
, Issue.5
, pp. 510-522
-
-
Noushmehr, H.1
Weisenberger, D.J.2
Diefes, K.3
Phillips, H.S.4
Pujara, K.5
Berman, B.P.6
-
9
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
PubMed PMID: 18772396; PubMed Central PMCID: PMC2820389.
-
Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P, et al. An integrated genomic analysis of human glioblastoma multiforme. Science (2008) 321(5897):1807-12. doi: 10.1126/science.1164382. PubMed PMID: 18772396; PubMed Central PMCID: PMC2820389.
-
(2008)
Science
, vol.321
, Issue.5897
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
-
10
-
-
84883464949
-
ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis
-
PubMed PMID: 23904111., Epub 2013/08/02
-
Wiestler B, Capper D, Holland-Letz T, Korshunov A, von Deimling A, Pfister SM, et al. ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis. Acta Neuropathol (2013) 126(3):443-51. Epub 2013/08/02. doi: 10.1007/s00401-013-1156-z. PubMed PMID: 23904111.
-
(2013)
Acta Neuropathol
, vol.126
, Issue.3
, pp. 443-451
-
-
Wiestler, B.1
Capper, D.2
Holland-Letz, T.3
Korshunov, A.4
von Deimling, A.5
Pfister, S.M.6
-
11
-
-
83355163405
-
Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin
-
JCO.2010.33.8715 [pii] PubMed PMID: 22025148; PubMed Central PMCID: PMC3236649., Epub 2011/10/26
-
Lai A, Kharbanda S, Pope WB, Tran A, Solis OE, Peale F, et al. Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin. J Clin Oncol (2011) 29(34):4482-90. Epub 2011/10/26. doi: JCO.2010.33.8715 [pii] 10.1200/JCO.2010.33.8715. PubMed PMID: 22025148; PubMed Central PMCID: PMC3236649.
-
(2011)
J Clin Oncol
, vol.29
, Issue.34
, pp. 4482-4490
-
-
Lai, A.1
Kharbanda, S.2
Pope, W.B.3
Tran, A.4
Solis, O.E.5
Peale, F.6
-
12
-
-
84906557615
-
A vaccine targeting mutant IDH1 induces antitumour immunity
-
nature13387 [pii] PubMed PMID: 25043048., Epub 2014/07/22
-
Schumacher T, Bunse L, Pusch S, Sahm F, Wiestler B, Quandt J, et al. A vaccine targeting mutant IDH1 induces antitumour immunity. Nature (2014) 512(7514):324-7. Epub 2014/07/22. doi: nature13387 [pii] 10.1038/nature13387. PubMed PMID: 25043048.
-
(2014)
Nature
, vol.512
, Issue.7514
, pp. 324-327
-
-
Schumacher, T.1
Bunse, L.2
Pusch, S.3
Sahm, F.4
Wiestler, B.5
Quandt, J.6
-
13
-
-
73349134695
-
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide
-
JCO.2009.23.6497 [pii] PubMed PMID: 19901110., Epub 2009/11/11
-
Wick W, Hartmann C, Engel C, Stoffels M, Felsberg J, Stockhammer F, et al. NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. J Clin Oncol (2009) 27(35):5874-80. Epub 2009/11/11. doi: JCO.2009.23.6497 [pii] 10.1200/JCO.2009.23.6497. PubMed PMID: 19901110.
-
(2009)
J Clin Oncol
, vol.27
, Issue.35
, pp. 5874-5880
-
-
Wick, W.1
Hartmann, C.2
Engel, C.3
Stoffels, M.4
Felsberg, J.5
Stockhammer, F.6
-
14
-
-
84873338121
-
Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402
-
JCO.2012.43.2674 [pii] PubMed PMID: 23071247; PubMed Central PMCID: PMC3732012., Epub 2012/10/17
-
Cairncross G, Wang M, Shaw E, Jenkins R, Brachman D, Buckner J, et al. Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402. J Clin Oncol (2013) 31(3):337-43. Epub 2012/10/17. doi: JCO.2012.43.2674 [pii] 10.1200/JCO.2012.43.2674. PubMed PMID: 23071247; PubMed Central PMCID: PMC3732012.
-
(2013)
J Clin Oncol
, vol.31
, Issue.3
, pp. 337-343
-
-
Cairncross, G.1
Wang, M.2
Shaw, E.3
Jenkins, R.4
Brachman, D.5
Buckner, J.6
-
15
-
-
84873345824
-
Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951
-
JCO.2012.43.2229 [pii] PubMed PMID: 23071237., Epub 2012/10/17
-
van den Bent MJ, Brandes AA, Taphoorn MJ, Kros JM, Kouwenhoven MC, Delattre JY, et al. Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951. J Clin Oncol (2013) 31(3):344-50. Epub 2012/10/17. doi: JCO.2012.43.2229 [pii] 10.1200/JCO.2012.43.2229. PubMed PMID: 23071237.
-
(2013)
J Clin Oncol
, vol.31
, Issue.3
, pp. 344-350
-
-
van den Bent, M.J.1
Brandes, A.A.2
Taphoorn, M.J.3
Kros, J.M.4
Kouwenhoven, M.C.5
Delattre, J.Y.6
-
16
-
-
84868625787
-
Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
-
588 [pii]PubMed PMID: 22869205; PubMed Central PMCID: PMC3443254., Epub 2012/08/08
-
Jiao Y, Killela PJ, Reitman ZJ, Rasheed AB, Heaphy CM, de Wilde RF, et al. Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas. Oncotarget (2012) 3(7):709-22. Epub 2012/08/08. doi: 588 [pii]. PubMed PMID: 22869205; PubMed Central PMCID: PMC3443254.
-
(2012)
Oncotarget
, vol.3
, Issue.7
, pp. 709-722
-
-
Jiao, Y.1
Killela, P.J.2
Reitman, Z.J.3
Rasheed, A.B.4
Heaphy, C.M.5
de Wilde, R.F.6
-
17
-
-
72049125350
-
Cancer associated IDH1 mutations produce 2-hydroxyglutarate
-
nature08617 [pii] PubMed PMID: 19935646., Epub 2009/11/26
-
Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, et al. Cancer associated IDH1 mutations produce 2-hydroxyglutarate. Nature (2009) 462(7274):739-44. Epub 2009/11/26. doi: nature08617 [pii]10.1038/nature08617. PubMed PMID: 19935646.
-
(2009)
Nature
, vol.462
, Issue.7274
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
Bennett, B.D.4
Bittinger, M.A.5
Driggers, E.M.6
-
18
-
-
84899415660
-
Lactate dehydrogenase A silencing in IDH mutant gliomas
-
not243 [pii] PubMed PMID: 24366912., Epub 2013/12/25
-
Chesnelong C, Chaumeil MM, Blough MD, Al-Najjar M, Stechishin OD, Chan JA, et al. Lactate dehydrogenase A silencing in IDH mutant gliomas. Neuro Oncol (2013) 16(5):686-95. Epub 2013/12/25. doi: not243 [pii]10.1093/neuonc/not243. PubMed PMID: 24366912.
-
(2013)
Neuro Oncol
, vol.16
, Issue.5
, pp. 686-695
-
-
Chesnelong, C.1
Chaumeil, M.M.2
Blough, M.D.3
Al-Najjar, M.4
Stechishin, O.D.5
Chan, J.A.6
-
19
-
-
75749115909
-
A multigene predictor of outcome in glioblastoma
-
PubMed PMID: 20150367; PubMed Central PMCID: PMC2940562.
-
Colman H, Zhang L, Sulman EP, McDonald JM, Shooshtari NL, Rivera A, et al. A multigene predictor of outcome in glioblastoma. Neuro Oncol (2010) 12(1):49-57. doi: 10.1093/neuonc/nop007. PubMed PMID: 20150367; PubMed Central PMCID: PMC2940562.
-
(2010)
Neuro Oncol
, vol.12
, Issue.1
, pp. 49-57
-
-
Colman, H.1
Zhang, L.2
Sulman, E.P.3
McDonald, J.M.4
Shooshtari, N.L.5
Rivera, A.6
-
20
-
-
79957889613
-
DecisionDx-GBM Gene Expression Assay for Prognostic Testing in Glioblastoma Multiform.
-
Epub 2010/10/26. PubMed PMID: 20972474; PubMed Central PMCID: PMC2957243.
-
Allingham-Hawkins D, Lea A, Levine S. DecisionDx-GBM Gene Expression Assay for Prognostic Testing in Glioblastoma Multiform. PLoS Curr (2010) 2:RRN1186. Epub 2010/10/26. doi: 10.1371/currents.RRN1186k/-/-/1i0b298tuv2uk/2 [pii]. PubMed PMID: 20972474; PubMed Central PMCID: PMC2957243.
-
(2010)
PLoS Curr
, vol.2
-
-
Allingham-Hawkins, D.1
Lea, A.2
Levine, S.3
-
21
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
PubMed PMID: 15758009.
-
Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med (2005) 352(10):987-96. doi: 10.1056/NEJMoa043330. PubMed PMID: 15758009.
-
(2005)
N Engl J Med
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.6
-
22
-
-
67649873216
-
Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy
-
6605127 [pii] PubMed PMID: 19536096., Epub 2009/06/19
-
Dunn J, Baborie A, Alam F, Joyce K, Moxham M, Sibson R, et al. Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy. Br J Cancer (2009) 101(1):124-31. Epub 2009/06/19. doi: 6605127 [pii] 10.1038/sj.bjc.6605127. PubMed PMID: 19536096.
-
(2009)
Br J Cancer
, vol.101
, Issue.1
, pp. 124-131
-
-
Dunn, J.1
Baborie, A.2
Alam, F.3
Joyce, K.4
Moxham, M.5
Sibson, R.6
-
23
-
-
75849146316
-
MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma.
-
nop020 [pii]Epub 2010/02/13. PubMed PMID: 20150378.
-
Rivera AL, Pelloski CE, Gilbert MR, Colman H, De La Cruz C, Sulman EP, et al. MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma. Neuro Oncol (2010) 12(2):116-21. Epub 2010/02/13. doi: nop020 [pii]10.1093/neuonc/nop020. PubMed PMID: 20150378.
-
(2010)
Neuro Oncol
, vol.12
, Issue.2
, pp. 116-121
-
-
Rivera, A.L.1
Pelloski, C.E.2
Gilbert, M.R.3
Colman, H.4
De La Cruz, C.5
Sulman, E.P.6
-
24
-
-
84904070681
-
MGMT testing-the challenges for biomarker-based glioma treatment
-
nrneurol.2014.100 [pii] PubMed PMID: 24912512., Epub 2014/06/11
-
Wick W, Weller M, van den Bent M, Sanson M, Weiler M, von Deimling A, et al. MGMT testing-the challenges for biomarker-based glioma treatment. Nat Rev Neurol (2014) 10(7):372-85. Epub 2014/06/11. doi: nrneurol.2014.100 [pii] 10.1038/nrneurol.2014.100. PubMed PMID: 24912512.
-
(2014)
Nat Rev Neurol
, vol.10
, Issue.7
, pp. 372-385
-
-
Wick, W.1
Weller, M.2
van den Bent, M.3
Sanson, M.4
Weiler, M.5
von Deimling, A.6
-
25
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
PubMed PMID: 15758010.
-
Hegi ME, Diserens AC, Gorlia T, Hamou MF, de Tribolet N, Weller M, et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med (2005) 352(10):997-1003. doi: 10.1056/NEJMoa043331. PubMed PMID: 15758010.
-
(2005)
N Engl J Med
, vol.352
, Issue.10
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
Hamou, M.F.4
de Tribolet, N.5
Weller, M.6
-
26
-
-
19244370208
-
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
-
Epub 2000/05/16. PubMed PMID: 10811111.
-
Esteller M, Toyota M, Sanchez-Cespedes M, Capella G, Peinado MA, Watkins DN, et al. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis. Cancer Res (2000) 60(9):2368-71. Epub 2000/05/16. PubMed PMID: 10811111.
-
(2000)
Cancer Res
, vol.60
, Issue.9
, pp. 2368-2371
-
-
Esteller, M.1
Toyota, M.2
Sanchez-Cespedes, M.3
Capella, G.4
Peinado, M.A.5
Watkins, D.N.6
-
27
-
-
33749075532
-
Phase II trial of lomustine plus temozolomide chemotherapy in addition to radiotherapy in newly diagnosed glioblastoma: UKT-03
-
24/27/4412 [pii] PubMed PMID: 16983109., Epub 2006/09/20
-
Herrlinger U, Rieger J, Koch D, Loeser S, Blaschke B, Kortmann RD, et al. Phase II trial of lomustine plus temozolomide chemotherapy in addition to radiotherapy in newly diagnosed glioblastoma: UKT-03. J Clin Oncol (2006) 24(27):4412-7. Epub 2006/09/20. doi: 24/27/4412 [pii] 10.1200/JCO.2006.06.9104. PubMed PMID: 16983109.
-
(2006)
J Clin Oncol
, vol.24
, Issue.27
, pp. 4412-4417
-
-
Herrlinger, U.1
Rieger, J.2
Koch, D.3
Loeser, S.4
Blaschke, B.5
Kortmann, R.D.6
-
28
-
-
73349103157
-
Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network
-
JCO.2009.23.0805 [pii] PubMed PMID: 19805672., Epub 2009/10/07
-
Weller M, Felsberg J, Hartmann C, Berger H, Steinbach JP, Schramm J, et al. Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network. J Clin Oncol (2009) 27(34):5743-50. Epub 2009/10/07. doi: JCO.2009.23.0805 [pii]10.1200/JCO.2009.23.0805. PubMed PMID: 19805672.
-
(2009)
J Clin Oncol
, vol.27
, Issue.34
, pp. 5743-5750
-
-
Weller, M.1
Felsberg, J.2
Hartmann, C.3
Berger, H.4
Steinbach, J.P.5
Schramm, J.6
-
29
-
-
84863091424
-
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial
-
S1470-2045(12)70164-X [pii] PubMed PMID: 22578793., Epub 2012/05/15
-
Wick W, Platten M, Meisner C, Felsberg J, Tabatabai G, Simon M, et al. Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial. Lancet Oncol (2012) 13(7):707-15. Epub 2012/05/15. doi: S1470-2045(12)70164-X [pii]10.1016/S1470-2045(12)70164-X. PubMed PMID: 22578793.
-
(2012)
Lancet Oncol
, vol.13
, Issue.7
, pp. 707-715
-
-
Wick, W.1
Platten, M.2
Meisner, C.3
Felsberg, J.4
Tabatabai, G.5
Simon, M.6
-
30
-
-
84865558322
-
Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial
-
S1470-2045(12)70265-6 [pii] PubMed PMID: 22877848., Epub 2012/08/11
-
Malmstrom A, Gronberg BH, Marosi C, Stupp R, Frappaz D, Schultz H, et al. Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial. Lancet Oncol (2012) 13(9):916-26. Epub 2012/08/11. doi: S1470-2045(12)70265-6 [pii]10.1016/S1470-2045(12)70265-6. PubMed PMID: 22877848.
-
(2012)
Lancet Oncol
, vol.13
, Issue.9
, pp. 916-926
-
-
Malmstrom, A.1
Gronberg, B.H.2
Marosi, C.3
Stupp, R.4
Frappaz, D.5
Schultz, H.6
-
31
-
-
84891957320
-
Reduction of MLH1 and PMS2 confers temozolomide resistance and is associated with recurrence of glioblastoma.
-
PubMed PMID: 24259277.
-
Shinsato Y, Furukawa T, Yunoue S, Yonezawa H, Minami K, Nishizawa Y, et al. Reduction of MLH1 and PMS2 confers temozolomide resistance and is associated with recurrence of glioblastoma. Oncotarget (2013) 4(12):2261-70. PubMed PMID: 24259277.
-
(2013)
Oncotarget
, vol.4
, Issue.12
, pp. 2261-2270
-
-
Shinsato, Y.1
Furukawa, T.2
Yunoue, S.3
Yonezawa, H.4
Minami, K.5
Nishizawa, Y.6
-
32
-
-
84907426055
-
Novel MSH6 Mutations in Treatment-Naive Glioblastoma and Anaplastic Oligodendroglioma Contribute to Temozolomide Resistance Independently of MGMT Promoter Methylation
-
1078-0432.CCR-13-1856 [pii] PubMed PMID: 25078279., Epub 2014/08/01
-
Nguyen SA, Stechishin OD, Luchman HA, Lun XQ, Senger DL, Robbins SM, et al. Novel MSH6 Mutations in Treatment-Naive Glioblastoma and Anaplastic Oligodendroglioma Contribute to Temozolomide Resistance Independently of MGMT Promoter Methylation. Clin Cancer Res (2014) 20(18):4894-903. Epub 2014/08/01. doi: 1078-0432.CCR-13-1856 [pii]10.1158/1078-0432.CCR-13-1856. PubMed PMID: 25078279.
-
(2014)
Clin Cancer Res
, vol.20
, Issue.18
, pp. 4894-4903
-
-
Nguyen, S.A.1
Stechishin, O.D.2
Luchman, H.A.3
Lun, X.Q.4
Senger, D.L.5
Robbins, S.M.6
-
33
-
-
79958072588
-
Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas
-
PubMed PMID: 21425258.
-
Felsberg J, Thon N, Eigenbrod S, Hentschel B, Sabel MC, Westphal M, et al. Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas. Int J Cancer (2011) 129(3):659-70. doi: 10.1002/ijc.26083. PubMed PMID: 21425258.
-
(2011)
Int J Cancer
, vol.129
, Issue.3
, pp. 659-670
-
-
Felsberg, J.1
Thon, N.2
Eigenbrod, S.3
Hentschel, B.4
Sabel, M.C.5
Westphal, M.6
-
34
-
-
77956608245
-
The expression of mismatch repair proteins MLH1, MSH2 and MSH6 correlates with the Ki67 proliferation index and survival in patients with recurrent glioblastoma
-
PubMed PMID: 20223108.
-
Stark AM, Doukas A, Hugo HH, Mehdorn HM. The expression of mismatch repair proteins MLH1, MSH2 and MSH6 correlates with the Ki67 proliferation index and survival in patients with recurrent glioblastoma. Neurol Res (2010) 32(8):816-20. doi: 10.1179/016164110X12645013515052. PubMed PMID: 20223108.
-
(2010)
Neurol Res
, vol.32
, Issue.8
, pp. 816-820
-
-
Stark, A.M.1
Doukas, A.2
Hugo, H.H.3
Mehdorn, H.M.4
-
35
-
-
68949149010
-
Identification of regions correlating MGMT promoter methylation and gene expression in glioblastomas
-
PubMed PMID: 19224763; PubMed Central PMCID: PMC2743215.
-
Everhard S, Tost J, El Abdalaoui H, Criniere E, Busato F, Marie Y, et al. Identification of regions correlating MGMT promoter methylation and gene expression in glioblastomas. Neuro Oncol (2009) 11(4):348-56. doi: 10.1215/15228517-2009-001. PubMed PMID: 19224763; PubMed Central PMCID: PMC2743215.
-
(2009)
Neuro Oncol
, vol.11
, Issue.4
, pp. 348-356
-
-
Everhard, S.1
Tost, J.2
El Abdalaoui, H.3
Criniere, E.4
Busato, F.5
Marie, Y.6
-
36
-
-
0029803785
-
Induction of the alkyltransferase (MGMT) gene by DNA damaging agents and the glucocorticoid dexamethasone and comparison with the response of base excision repair genes.
-
PubMed PMID: 8968045.
-
Grombacher T, Mitra S, Kaina B. Induction of the alkyltransferase (MGMT) gene by DNA damaging agents and the glucocorticoid dexamethasone and comparison with the response of base excision repair genes. Carcinogenesis (1996) 17(11):2329-36. PubMed PMID: 8968045.
-
(1996)
Carcinogenesis
, vol.17
, Issue.11
, pp. 2329-2336
-
-
Grombacher, T.1
Mitra, S.2
Kaina, B.3
-
37
-
-
0025767132
-
Inducibility of the DNA repair gene encoding O6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments.
-
PubMed PMID: 1875945; PubMed Central PMCID: PMC361355.
-
Fritz G, Tano K, Mitra S, Kaina B. Inducibility of the DNA repair gene encoding O6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments. Mol Cell Biol (1991) 11(9):4660-8. PubMed PMID: 1875945; PubMed Central PMCID: PMC361355.
-
(1991)
Mol Cell Biol
, vol.11
, Issue.9
, pp. 4660-4668
-
-
Fritz, G.1
Tano, K.2
Mitra, S.3
Kaina, B.4
-
38
-
-
1942469956
-
MGMT: its role in cancer aetiology and cancer therapeutics
-
PubMed PMID: 15057289.
-
Gerson SL. MGMT: its role in cancer aetiology and cancer therapeutics. Nat Rev Cancer (2004) 4(4):296-307. doi: 10.1038/nrc1319. PubMed PMID: 15057289.
-
(2004)
Nat Rev Cancer
, vol.4
, Issue.4
, pp. 296-307
-
-
Gerson, S.L.1
-
39
-
-
79251577095
-
O6-Methylguanine-DNA methyltransferase protein expression by immunohistochemistry in brain and non-brain systemic tumours: systematic review and meta-analysis of correlation with methylation-specific polymerase chain reaction.
-
PubMed PMID: 21269507; PubMed Central PMCID: PMC3039628.
-
Brell M, Ibanez J, Tortosa A. O6-Methylguanine-DNA methyltransferase protein expression by immunohistochemistry in brain and non-brain systemic tumours: systematic review and meta-analysis of correlation with methylation-specific polymerase chain reaction. BMC Cancer (2011) 11:35. doi: 10.1186/1471-2407-11-35. PubMed PMID: 21269507; PubMed Central PMCID: PMC3039628.
-
(2011)
BMC Cancer
, vol.11
, pp. 35
-
-
Brell, M.1
Ibanez, J.2
Tortosa, A.3
-
40
-
-
75149166496
-
MGMT promoter methylation in malignant gliomas: ready for personalized medicine?
-
PubMed PMID: 19997073.
-
Weller M, Stupp R, Reifenberger G, Brandes AA, van den Bent MJ, Wick W, et al. MGMT promoter methylation in malignant gliomas: ready for personalized medicine? Nat Rev Neurol (2010) 6(1):39-51. doi: 10.1038/nrneurol.2009.197. PubMed PMID: 19997073.
-
(2010)
Nat Rev Neurol
, vol.6
, Issue.1
, pp. 39-51
-
-
Weller, M.1
Stupp, R.2
Reifenberger, G.3
Brandes, A.A.4
van den Bent, M.J.5
Wick, W.6
-
41
-
-
84865310348
-
Molecular targeted therapy in recurrent glioblastoma: current challenges and future directions
-
PubMed PMID: 22731981.
-
Patel M, Vogelbaum MA, Barnett GH, Jalali R, Ahluwalia MS. Molecular targeted therapy in recurrent glioblastoma: current challenges and future directions. Expert Opin Investig Drugs (2012) 21(9):1247-66. doi: 10.1517/13543784.2012.703177. PubMed PMID: 22731981.
-
(2012)
Expert Opin Investig Drugs
, vol.21
, Issue.9
, pp. 1247-1266
-
-
Patel, M.1
Vogelbaum, M.A.2
Barnett, G.H.3
Jalali, R.4
Ahluwalia, M.S.5
-
42
-
-
14644412873
-
Prognostic effect of epidermal growth factor receptor and EGFRvIII in glioblastoma multiforme patients
-
PubMed PMID: 15746047.
-
Heimberger AB, Hlatky R, Suki D, Yang D, Weinberg J, Gilbert M, et al. Prognostic effect of epidermal growth factor receptor and EGFRvIII in glioblastoma multiforme patients. Clin Cancer Res (2005) 11(4):1462-6. doi: 10.1158/1078-0432.CCR-04-1737. PubMed PMID: 15746047.
-
(2005)
Clin Cancer Res
, vol.11
, Issue.4
, pp. 1462-1466
-
-
Heimberger, A.B.1
Hlatky, R.2
Suki, D.3
Yang, D.4
Weinberg, J.5
Gilbert, M.6
-
43
-
-
34250189213
-
Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma
-
PubMed PMID: 17538175.
-
Pelloski CE, Ballman KV, Furth AF, Zhang L, Lin E, Sulman EP, et al. Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma. J Clin Oncol (2007) 25(16):2288-94. doi: 10.1200/JCO.2006.08.0705. PubMed PMID: 17538175.
-
(2007)
J Clin Oncol
, vol.25
, Issue.16
, pp. 2288-2294
-
-
Pelloski, C.E.1
Ballman, K.V.2
Furth, A.F.3
Zhang, L.4
Lin, E.5
Sulman, E.P.6
-
44
-
-
84870065591
-
Epidermal growth factor receptor: a re-emerging target in glioblastoma
-
PubMed PMID: 23007009., Epub 2012/09/26
-
Hegi ME, Rajakannu P, Weller M. Epidermal growth factor receptor: a re-emerging target in glioblastoma. Curr Opin Neurol (2012) 25(6):774-9. Epub 2012/09/26. doi: 10.1097/WCO.0b013e328359b0bc. PubMed PMID: 23007009.
-
(2012)
Curr Opin Neurol
, vol.25
, Issue.6
, pp. 774-779
-
-
Hegi, M.E.1
Rajakannu, P.2
Weller, M.3
-
45
-
-
80051659072
-
Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: an ANOCEF phase II trial
-
JCO.2011.34.8086 [pii] PubMed PMID: 21709196., Epub 2011/06/29
-
Gallego Perez-Larraya J, Ducray F, Chinot O, Catry-Thomas I, Taillandier L, Guillamo JS, et al. Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: an ANOCEF phase II trial. J Clin Oncol (2011) 29(22):3050-5. Epub 2011/06/29. doi: JCO.2011.34.8086 [pii]10.1200/JCO.2011.34.8086. PubMed PMID: 21709196.
-
(2011)
J Clin Oncol
, vol.29
, Issue.22
, pp. 3050-3055
-
-
Gallego Perez-Larraya, J.1
Ducray, F.2
Chinot, O.3
Catry-Thomas, I.4
Taillandier, L.5
Guillamo, J.S.6
-
46
-
-
79952907554
-
Rindopepimut, a 14-mer injectable peptide vaccine against EGFRvIII for the potential treatment of glioblastoma multiforme.
-
Epub 2010/12/15. PubMed PMID: 21154166.
-
Del Vecchio CA, Wong AJ. Rindopepimut, a 14-mer injectable peptide vaccine against EGFRvIII for the potential treatment of glioblastoma multiforme. Curr Opin Mol Ther (2010) 12(6):741-54. Epub 2010/12/15. PubMed PMID: 21154166.
-
(2010)
Curr Opin Mol Ther
, vol.12
, Issue.6
, pp. 741-754
-
-
Del Vecchio, C.A.1
Wong, A.J.2
-
47
-
-
84873204700
-
Rindopepimut: an evidence-based review of its therapeutic potential in the treatment of EGFRvIII-positive glioblastoma.
-
Epub 2012/10/12. PubMed PMID: 23055947; PubMed Central PMCID: PMC3459544.
-
Babu R, Adamson DC. Rindopepimut: an evidence-based review of its therapeutic potential in the treatment of EGFRvIII-positive glioblastoma. Core Evid (2012) 7:93-103. Epub 2012/10/12. doi: 10.2147/CE.S29001ce-7-093 [pii]. PubMed PMID: 23055947; PubMed Central PMCID: PMC3459544.
-
(2012)
Core Evid
, vol.7
, pp. 93-103
-
-
Babu, R.1
Adamson, D.C.2
-
48
-
-
84895922426
-
Assessment and prognostic significance of the epidermal growth factor receptor vIII mutation in glioblastoma patients treated with concurrent and adjuvant temozolomide radiochemotherapy
-
PubMed PMID: 24614983., Epub 2014/03/13
-
Weller M, Kaulich K, Hentschel B, Felsberg J, Gramatzki D, Pietsch T, et al. Assessment and prognostic significance of the epidermal growth factor receptor vIII mutation in glioblastoma patients treated with concurrent and adjuvant temozolomide radiochemotherapy. Int J Cancer (2014) 134(10):2437-47. Epub 2014/03/13. doi: 10.1002/ijc.28576. PubMed PMID: 24614983.
-
(2014)
Int J Cancer
, vol.134
, Issue.10
, pp. 2437-2447
-
-
Weller, M.1
Kaulich, K.2
Hentschel, B.3
Felsberg, J.4
Gramatzki, D.5
Pietsch, T.6
-
49
-
-
84876067164
-
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
-
PubMed PMID: 23530248; PubMed Central PMCID: PMC3625331.
-
Killela PJ, Reitman ZJ, Jiao Y, Bettegowda C, Agrawal N, Diaz LA, Jr., et al. TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. Proceedings of the National Academy of Sciences of the United States of America (2013) 110(15):6021-6. doi: 10.1073/pnas.1303607110. PubMed PMID: 23530248; PubMed Central PMCID: PMC3625331.
-
(2013)
Proceedings of the National Academy of Sciences of the United States of America
, vol.110
, Issue.15
, pp. 6021-6026
-
-
Killela, P.J.1
Reitman, Z.J.2
Jiao, Y.3
Bettegowda, C.4
Agrawal, N.5
Diaz Jr, L.A.6
-
50
-
-
84874598318
-
Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
-
PubMed PMID: 23412337; PubMed Central PMCID: PMC3593922.
-
Sottoriva A, Spiteri I, Piccirillo SG, Touloumis A, Collins VP, Marioni JC, et al. Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics. Proceedings of the National Academy of Sciences of the United States of America (2013) 110(10):4009-14. doi: 10.1073/pnas.1219747110. PubMed PMID: 23412337; PubMed Central PMCID: PMC3593922.
-
(2013)
Proceedings of the National Academy of Sciences of the United States of America
, vol.110
, Issue.10
, pp. 4009-4014
-
-
Sottoriva, A.1
Spiteri, I.2
Piccirillo, S.G.3
Touloumis, A.4
Collins, V.P.5
Marioni, J.C.6
-
51
-
-
75549083303
-
Tumor heterogeneity: causes and consequences
-
PubMed PMID: 19931353; PubMed Central PMCID: PMC2814927.
-
Marusyk A, Polyak K. Tumor heterogeneity: causes and consequences. Biochim Biophys Acta (2010) 1805(1):105-17. doi: 10.1016/j.bbcan.2009.11.002. PubMed PMID: 19931353; PubMed Central PMCID: PMC2814927.
-
(2010)
Biochim Biophys Acta
, vol.1805
, Issue.1
, pp. 105-117
-
-
Marusyk, A.1
Polyak, K.2
-
52
-
-
84881477572
-
Cancer heterogeneity--a multifaceted view
-
PubMed PMID: 23846313; PubMed Central PMCID: PMC3736134.
-
De Sousa EMF, Vermeulen L, Fessler E, Medema JP. Cancer heterogeneity--a multifaceted view. EMBO Rep (2013) 14(8):686-95. doi: 10.1038/embor.2013.92. PubMed PMID: 23846313; PubMed Central PMCID: PMC3736134.
-
(2013)
EMBO Rep
, vol.14
, Issue.8
, pp. 686-695
-
-
De Sousa, E.M.F.1
Vermeulen, L.2
Fessler, E.3
Medema, J.P.4
-
53
-
-
84859940323
-
Characterizing mutational heterogeneity in a glioblastoma patient with double recurrence
-
PubMed PMID: 22536362; PubMed Central PMCID: PMC3335059.
-
Nickel GC, Barnholtz-Sloan J, Gould MP, McMahon S, Cohen A, Adams MD, et al. Characterizing mutational heterogeneity in a glioblastoma patient with double recurrence. PLoS One (2012) 7(4):e35262. doi: 10.1371/journal.pone.0035262. PubMed PMID: 22536362; PubMed Central PMCID: PMC3335059.
-
(2012)
PLoS One
, vol.7
, Issue.4
, pp. e35262
-
-
Nickel, G.C.1
Barnholtz-Sloan, J.2
Gould, M.P.3
McMahon, S.4
Cohen, A.5
Adams, M.D.6
-
54
-
-
0034741232
-
Treatment of malignant glioma: a problem beyond the margins of resection.
-
Epub 2001/04/24. PubMed PMID: 11315255.
-
Giese A, Westphal M. Treatment of malignant glioma: a problem beyond the margins of resection. J Cancer Res Clin Oncol (2001) 127(4):217-25. Epub 2001/04/24. PubMed PMID: 11315255.
-
(2001)
J Cancer Res Clin Oncol
, vol.127
, Issue.4
, pp. 217-225
-
-
Giese, A.1
Westphal, M.2
-
55
-
-
20644454157
-
Surgery for malignant gliomas: mechanistic reasoning and slippery statistics
-
S1474-4422(05)70118-6 [pii] PubMed PMID: 15963444., Epub 2005/06/21
-
Mitchell P, Ellison DW, Mendelow AD. Surgery for malignant gliomas: mechanistic reasoning and slippery statistics. Lancet Neurol (2005) 4(7):413-22. Epub 2005/06/21. doi: S1474-4422(05)70118-6 [pii]10.1016/S1474-4422(05)70118-6. PubMed PMID: 15963444.
-
(2005)
Lancet Neurol
, vol.4
, Issue.7
, pp. 413-422
-
-
Mitchell, P.1
Ellison, D.W.2
Mendelow, A.D.3
-
56
-
-
23944445606
-
Neural stem cells and the origin of gliomas
-
353/8/811 [pii] PubMed PMID: 16120861., Epub 2005/08/27
-
Sanai N, Alvarez-Buylla A, Berger MS. Neural stem cells and the origin of gliomas. N Engl J Med (2005) 353(8):811-22. Epub 2005/08/27. doi: 353/8/811 [pii]10.1056/NEJMra043666. PubMed PMID: 16120861.
-
(2005)
N Engl J Med
, vol.353
, Issue.8
, pp. 811-822
-
-
Sanai, N.1
Alvarez-Buylla, A.2
Berger, M.S.3
-
57
-
-
33645986455
-
Fluorescence guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial
-
S1470-2045(06)70665-9 [pii] PubMed PMID: 16648043., Epub 2006/05/02
-
Stummer W, Pichlmeier U, Meinel T, Wiestler OD, Zanella F, Reulen HJ. Fluorescence guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol (2006) 7(5):392-401. Epub 2006/05/02. doi: S1470-2045(06)70665-9 [pii]10.1016/S1470-2045(06)70665-9. PubMed PMID: 16648043.
-
(2006)
Lancet Oncol
, vol.7
, Issue.5
, pp. 392-401
-
-
Stummer, W.1
Pichlmeier, U.2
Meinel, T.3
Wiestler, O.D.4
Zanella, F.5
Reulen, H.J.6
-
58
-
-
0017167185
-
The clonal evolution of tumor cell populations.
-
PubMed PMID: 959840.
-
Nowell PC. The clonal evolution of tumor cell populations. Science (1976) 194(4260):23-8. PubMed PMID: 959840.
-
(1976)
Science
, vol.194
, Issue.4260
, pp. 23-28
-
-
Nowell, P.C.1
-
59
-
-
77958014613
-
How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine
-
PubMed PMID: 20877357; PubMed Central PMCID: PMC2967073.
-
Gerlinger M, Swanton C. How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine. Br J Cancer (2010) 103(8):1139-43. doi: 10.1038/sj.bjc.6605912. PubMed PMID: 20877357; PubMed Central PMCID: PMC2967073.
-
(2010)
Br J Cancer
, vol.103
, Issue.8
, pp. 1139-1143
-
-
Gerlinger, M.1
Swanton, C.2
-
60
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
PubMed PMID: 22397650.
-
Gerlinger M, Rowan AJ, Horswell S, Larkin J, Endesfelder D, Gronroos E, et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med (2012) 366(10):883-92. doi: 10.1056/NEJMoa1113205. PubMed PMID: 22397650.
-
(2012)
N Engl J Med
, vol.366
, Issue.10
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
Larkin, J.4
Endesfelder, D.5
Gronroos, E.6
-
61
-
-
84866163568
-
Cancer in light of experimental evolution
-
PubMed PMID: 22975007; PubMed Central PMCID: PMC3457634.
-
Sprouffske K, Merlo LM, Gerrish PJ, Maley CC, Sniegowski PD. Cancer in light of experimental evolution. Curr Biol (2012) 22(17):R762-71. doi: 10.1016/j.cub.2012.06.065. PubMed PMID: 22975007; PubMed Central PMCID: PMC3457634.
-
(2012)
Curr Biol
, vol.22
, Issue.17
, pp. R762-R771
-
-
Sprouffske, K.1
Merlo, L.M.2
Gerrish, P.J.3
Maley, C.C.4
Sniegowski, P.D.5
-
62
-
-
84875490185
-
Cancer genome landscapes
-
339/6127/1546 [pii] PubMed PMID: 23539594., Epub 2013/03/30
-
Vogelstein B, Papadopoulos N, Velculescu VE, Zhou S, Diaz LA, Jr., Kinzler KW. Cancer genome landscapes. Science (2013) 339(6127):1546-58. Epub 2013/03/30. doi: 339/6127/1546 [pii]10.1126/science.1235122. PubMed PMID: 23539594.
-
(2013)
Science
, vol.339
, Issue.6127
, pp. 1546-1558
-
-
Vogelstein, B.1
Papadopoulos, N.2
Velculescu, V.E.3
Zhou, S.4
Diaz Jr, L.A.5
Kinzler, K.W.6
-
63
-
-
84867121875
-
Intratumor heterogeneity: evolution through space and time
-
PubMed PMID: 23002210.
-
Swanton C. Intratumor heterogeneity: evolution through space and time. Cancer Res (2012) 72(19):4875-82. doi: 10.1158/0008-5472.CAN-12-2217. PubMed PMID: 23002210.
-
(2012)
Cancer Res
, vol.72
, Issue.19
, pp. 4875-4882
-
-
Swanton, C.1
-
64
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
PubMed PMID: 11689955.
-
Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature (2001) 414(6859):105-11. doi: 10.1038/35102167. PubMed PMID: 11689955.
-
(2001)
Nature
, vol.414
, Issue.6859
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
65
-
-
70349331502
-
A neurosurgeon's guide to stem cells, cancer stem cells, and brain tumor stem cells
-
PubMed PMID: 19625901.; discussion 49-50; quiz N6
-
Cheshier SH, Kalani MY, Lim M, Ailles L, Huhn SL, Weissman IL. A neurosurgeon's guide to stem cells, cancer stem cells, and brain tumor stem cells. Neurosurgery (2009) 65(2):237-49; discussion 49-50; quiz N6. doi: 10.1227/01.NEU.0000349921.14519.2A. PubMed PMID: 19625901.
-
(2009)
Neurosurgery
, vol.65
, Issue.2
, pp. 237-249
-
-
Cheshier, S.H.1
Kalani, M.Y.2
Lim, M.3
Ailles, L.4
Huhn, S.L.5
Weissman, I.L.6
-
66
-
-
34547432232
-
Incidence of gliomas by anatomic location
-
15228517-2007-016 [pii] PubMed PMID: 17522333., Epub 2007/05/25
-
Larjavaara S, Mantyla R, Salminen T, Haapasalo H, Raitanen J, Jaaskelainen J, et al. Incidence of gliomas by anatomic location. Neuro Oncol (2007) 9(3):319-25. Epub 2007/05/25. doi: 15228517-2007-016 [pii]10.1215/15228517-2007-016. PubMed PMID: 17522333.
-
(2007)
Neuro Oncol
, vol.9
, Issue.3
, pp. 319-325
-
-
Larjavaara, S.1
Mantyla, R.2
Salminen, T.3
Haapasalo, H.4
Raitanen, J.5
Jaaskelainen, J.6
-
67
-
-
47549090260
-
Clonal diversity in carcinomas: its implications for tumour progression and the contribution made to it by epithelial-mesenchymal transitions
-
PubMed PMID: 18071912.
-
Lyons JG, Lobo E, Martorana AM, Myerscough MR. Clonal diversity in carcinomas: its implications for tumour progression and the contribution made to it by epithelial-mesenchymal transitions. Clin Exp Metastasis (2008) 25(6):665-77. doi: 10.1007/s10585-007-9134-2. PubMed PMID: 18071912.
-
(2008)
Clin Exp Metastasis
, vol.25
, Issue.6
, pp. 665-677
-
-
Lyons, J.G.1
Lobo, E.2
Martorana, A.M.3
Myerscough, M.R.4
-
68
-
-
79958849271
-
Heterogeneity maintenance in glioblastoma: a social network
-
PubMed PMID: 21628493; PubMed Central PMCID: PMC3117065.
-
Bonavia R, Inda MM, Cavenee WK, Furnari FB. Heterogeneity maintenance in glioblastoma: a social network. Cancer Res (2011) 71(12):4055-60. doi: 10.1158/0008-5472.CAN-11-0153. PubMed PMID: 21628493; PubMed Central PMCID: PMC3117065.
-
(2011)
Cancer Res
, vol.71
, Issue.12
, pp. 4055-4060
-
-
Bonavia, R.1
Inda, M.M.2
Cavenee, W.K.3
Furnari, F.B.4
-
69
-
-
84860214990
-
Intra-tumour heterogeneity: a looking glass for cancer?
-
PubMed PMID: 22513401.
-
Marusyk A, Almendro V, Polyak K. Intra-tumour heterogeneity: a looking glass for cancer? Nat Rev Cancer (2012) 12(5):323-34. doi: 10.1038/nrc3261. PubMed PMID: 22513401.
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.5
, pp. 323-334
-
-
Marusyk, A.1
Almendro, V.2
Polyak, K.3
-
70
-
-
33846029123
-
A perivascular niche for brain tumor stem cells
-
S1535-6108(06)00369-2 [pii] PubMed PMID: 17222791., Epub 2007/01/16
-
Calabrese C, Poppleton H, Kocak M, Hogg TL, Fuller C, Hamner B, et al. A perivascular niche for brain tumor stem cells. Cancer Cell (2007) 11(1):69-82. Epub 2007/01/16. doi: S1535-6108(06)00369-2 [pii]10.1016/j.ccr.2006.11.020. PubMed PMID: 17222791.
-
(2007)
Cancer Cell
, vol.11
, Issue.1
, pp. 69-82
-
-
Calabrese, C.1
Poppleton, H.2
Kocak, M.3
Hogg, T.L.4
Fuller, C.5
Hamner, B.6
-
71
-
-
84900988325
-
HIF--regulate Notch signaling through competitive interaction with the intracellular domain of Notch receptors in glioma stem cells
-
S0304-3835(14)00204-3 [pii] PubMed PMID: 24705306., Epub 2014/04/08
-
Hu YY, Fu LA, Li SZ, Chen Y, Li JC, Han J, et al. HIF--regulate Notch signaling through competitive interaction with the intracellular domain of Notch receptors in glioma stem cells. Cancer Lett (2014) 349(1):67-76. Epub 2014/04/08. doi: S0304-3835(14)00204-3 [pii]10.1016/j.canlet.2014.03.035. PubMed PMID: 24705306.
-
(2014)
Cancer Lett
, vol.349
, Issue.1
, pp. 67-76
-
-
Hu, Y.Y.1
Fu, L.A.2
Li, S.Z.3
Chen, Y.4
Li, J.C.5
Han, J.6
-
72
-
-
84892373020
-
Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma
-
PubMed PMID: 24336570.
-
Johnson BE, Mazor T, Hong C, Barnes M, Aihara K, McLean CY, et al. Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma. Science (2014) 343(6167):189-93. doi: 10.1126/science.1239947. PubMed PMID: 24336570.
-
(2014)
Science
, vol.343
, Issue.6167
, pp. 189-193
-
-
Johnson, B.E.1
Mazor, T.2
Hong, C.3
Barnes, M.4
Aihara, K.5
McLean, C.Y.6
-
73
-
-
84921415076
-
Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity
-
PubMed PMID: 25561528; PubMed Central PMCID: PMCPmc4311802., Epub 2015/01/07
-
Meyer M, Reimand J, Lan X, Head R, Zhu X, Kushida M, et al. Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity. Proceedings of the National Academy of Sciences of the United States of America (2015) 112(3):851-6. Epub 2015/01/07. doi: 10.1073/pnas.1320611111. PubMed PMID: 25561528; PubMed Central PMCID: PMCPmc4311802.
-
(2015)
Proceedings of the National Academy of Sciences of the United States of America
, vol.112
, Issue.3
, pp. 851-856
-
-
Meyer, M.1
Reimand, J.2
Lan, X.3
Head, R.4
Zhu, X.5
Kushida, M.6
-
74
-
-
38649088636
-
Variation of O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma
-
Parkinson JF, Wheeler HR, Clarkson A, McKenzie CA, Biggs MT, Little NS, et al. Variation of O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma. J Neurooncol (2008) 87(1):71-8. doi: 10.1007/s11060-007-9486-PubMed PMID: 18004504.
-
(2008)
J Neurooncol
, vol.87
, Issue.1
, pp. 71-78
-
-
Parkinson, J.F.1
Wheeler, H.R.2
Clarkson, A.3
McKenzie, C.A.4
Biggs, M.T.5
Little, N.S.6
-
75
-
-
35649001325
-
Intratumoral homogeneity of MGMT promoter hypermethylation as demonstrated in serial stereotactic specimens from anaplastic astrocytomas and glioblastomas
-
PubMed PMID: 17691113.
-
Grasbon-Frodl EM, Kreth FW, Ruiter M, Schnell O, Bise K, Felsberg J, et al. Intratumoral homogeneity of MGMT promoter hypermethylation as demonstrated in serial stereotactic specimens from anaplastic astrocytomas and glioblastomas. Int J Cancer (2007) 121(11):2458-64. doi: 10.1002/ijc.23020. PubMed PMID: 17691113.
-
(2007)
Int J Cancer
, vol.121
, Issue.11
, pp. 2458-2464
-
-
Grasbon-Frodl, E.M.1
Kreth, F.W.2
Ruiter, M.3
Schnell, O.4
Bise, K.5
Felsberg, J.6
-
76
-
-
83455176258
-
Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma
-
PubMed PMID: 22137795.
-
Snuderl M, Fazlollahi L, Le LP, Nitta M, Zhelyazkova BH, Davidson CJ, et al. Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma. Cancer Cell (2011) 20(6):810-7. doi: 10.1016/j.ccr.2011.11.005. PubMed PMID: 22137795.
-
(2011)
Cancer Cell
, vol.20
, Issue.6
, pp. 810-817
-
-
Snuderl, M.1
Fazlollahi, L.2
Le, L.P.3
Nitta, M.4
Zhelyazkova, B.H.5
Davidson, C.J.6
-
77
-
-
84857397985
-
Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response
-
PubMed PMID: 22323597; PubMed Central PMCID: PMC3286976.
-
Szerlip NJ, Pedraza A, Chakravarty D, Azim M, McGuire J, Fang Y, et al. Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response. Proceedings of the National Academy of Sciences of the United States of America (2012) 109(8):3041-6. doi: 10.1073/pnas.1114033109. PubMed PMID: 22323597; PubMed Central PMCID: PMC3286976.
-
(2012)
Proceedings of the National Academy of Sciences of the United States of America
, vol.109
, Issue.8
, pp. 3041-3046
-
-
Szerlip, N.J.1
Pedraza, A.2
Chakravarty, D.3
Azim, M.4
McGuire, J.5
Fang, Y.6
-
78
-
-
84859376167
-
Receptor tyrosine kinase genes amplified in glioblastoma exhibit a mutual exclusivity in variable proportions reflective of individual tumor heterogeneity
-
PubMed PMID: 22311673.
-
Little SE, Popov S, Jury A, Bax DA, Doey L, Al-Sarraj S, et al. Receptor tyrosine kinase genes amplified in glioblastoma exhibit a mutual exclusivity in variable proportions reflective of individual tumor heterogeneity. Cancer Res (2012) 72(7):1614-20. doi: 10.1158/0008-5472.CAN-11-4069. PubMed PMID: 22311673.
-
(2012)
Cancer Res
, vol.72
, Issue.7
, pp. 1614-1620
-
-
Little, S.E.1
Popov, S.2
Jury, A.3
Bax, D.A.4
Doey, L.5
Al-Sarraj, S.6
-
79
-
-
84902668801
-
Single cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
-
science.1254257 [pii] PubMed PMID: 24925914; PubMed Central PMCID: PMC4123637., Epub 2014/06/14
-
Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, et al. Single cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science (2014) 344(6190):1396-401. Epub 2014/06/14. doi: science.1254257 [pii]10.1126/science.1254257. PubMed PMID: 24925914; PubMed Central PMCID: PMC4123637.
-
(2014)
Science
, vol.344
, Issue.6190
, pp. 1396-1401
-
-
Patel, A.P.1
Tirosh, I.2
Trombetta, J.J.3
Shalek, A.K.4
Gillespie, S.M.5
Wakimoto, H.6
-
80
-
-
84884407337
-
Tumour heterogeneity in the clinic
-
nature12627 [pii] PubMed PMID: 24048068., Epub 2013/09/21
-
Bedard PL, Hansen AR, Ratain MJ, Siu LL. Tumour heterogeneity in the clinic. Nature (2013) 501(7467):355-64. Epub 2013/09/21. doi: nature12627 [pii]10.1038/nature12627. PubMed PMID: 24048068.
-
(2013)
Nature
, vol.501
, Issue.7467
, pp. 355-364
-
-
Bedard, P.L.1
Hansen, A.R.2
Ratain, M.J.3
Siu, L.L.4
-
81
-
-
75049084471
-
Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma
-
PubMed PMID: 19562254., Epub 2009/06/30
-
Reardon DA, Desjardins A, Vredenburgh JJ, Gururangan S, Friedman AH, Herndon JE, 2nd, et al. Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma. J Neurooncol (2010) 96(2):219-30. Epub 2009/06/30. doi: 10.1007/s11060-009-9950-0. PubMed PMID: 19562254.
-
(2010)
J Neurooncol
, vol.96
, Issue.2
, pp. 219-230
-
-
Reardon, D.A.1
Desjardins, A.2
Vredenburgh, J.J.3
Gururangan, S.4
Friedman, A.H.5
Herndon, J.E.6
-
82
-
-
53749096014
-
Phase II study of imatinib in patients with recurrent gliomas of various histologies: a European Organisation for Research and Treatment of Cancer Brain Tumor Group Study
-
26/28/4659 [pii] PubMed PMID: 18824712., Epub 2008/10/01
-
Raymond E, Brandes AA, Dittrich C, Fumoleau P, Coudert B, Clement PM, et al. Phase II study of imatinib in patients with recurrent gliomas of various histologies: a European Organisation for Research and Treatment of Cancer Brain Tumor Group Study. J Clin Oncol (2008) 26(28):4659-65. Epub 2008/10/01. doi: 26/28/4659 [pii]10.1200/JCO.2008.16.9235. PubMed PMID: 18824712.
-
(2008)
J Clin Oncol
, vol.26
, Issue.28
, pp. 4659-4665
-
-
Raymond, E.1
Brandes, A.A.2
Dittrich, C.3
Fumoleau, P.4
Coudert, B.5
Clement, P.M.6
-
83
-
-
84871835992
-
Will kinase inhibitors make it as glioblastoma drugs?
-
Epub 2011/10/22. PubMed PMID: 22015553.
-
Mellinghoff IK, Schultz N, Mischel PS, Cloughesy TF. Will kinase inhibitors make it as glioblastoma drugs? Curr Top Microbiol Immunol (2012) 355:135-69. Epub 2011/10/22. doi: 10.1007/82_2011_178. PubMed PMID: 22015553.
-
(2012)
Curr Top Microbiol Immunol
, vol.355
, pp. 135-169
-
-
Mellinghoff, I.K.1
Schultz, N.2
Mischel, P.S.3
Cloughesy, T.F.4
-
84
-
-
84896933653
-
Phase I/II study of erlotinib and temsirolimus for patients with recurrent malignant gliomas: North American Brain Tumor Consortium trial 04-02
-
not247 [pii] PubMed PMID: 24470557., Epub 2014/01/29
-
Wen PY, Chang SM, Lamborn KR, Kuhn JG, Norden AD, Cloughesy TF, et al. Phase I/II study of erlotinib and temsirolimus for patients with recurrent malignant gliomas: North American Brain Tumor Consortium trial 04-02. Neuro Oncol (2014) 16(4):567-78. Epub 2014/01/29. doi: not247 [pii]10.1093/neuonc/not247. PubMed PMID: 24470557.
-
(2014)
Neuro Oncol
, vol.16
, Issue.4
, pp. 567-578
-
-
Wen, P.Y.1
Chang, S.M.2
Lamborn, K.R.3
Kuhn, J.G.4
Norden, A.D.5
Cloughesy, T.F.6
-
85
-
-
57049103401
-
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
-
ncb1800 [pii] PubMed PMID: 19011622; PubMed Central PMCID: PMC3423894., Epub 2008/11/18
-
Skog J, Wurdinger T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol (2008) 10(12):1470-6. Epub 2008/11/18. doi: ncb1800 [pii]10.1038/ncb1800. PubMed PMID: 19011622; PubMed Central PMCID: PMC3423894.
-
(2008)
Nat Cell Biol
, vol.10
, Issue.12
, pp. 1470-1476
-
-
Skog, J.1
Wurdinger, T.2
van Rijn, S.3
Meijer, D.H.4
Gainche, L.5
Sena-Esteves, M.6
-
86
-
-
84869429716
-
Assuring the quality of next-generation sequencing in clinical laboratory practice
-
nbt.2403 [pii] PubMed PMID: 23138292; PubMed Central PMCID: PMC3827024., Epub 2012/11/10
-
Gargis AS, Kalman L, Berry MW, Bick DP, Dimmock DP, Hambuch T, et al. Assuring the quality of next-generation sequencing in clinical laboratory practice. Nat Biotechnol (2012) 30(11):1033-6. Epub 2012/11/10. doi: nbt.2403 [pii]10.1038/nbt.2403. PubMed PMID: 23138292; PubMed Central PMCID: PMC3827024.
-
(2012)
Nat Biotechnol
, vol.30
, Issue.11
, pp. 1033-1036
-
-
Gargis, A.S.1
Kalman, L.2
Berry, M.W.3
Bick, D.P.4
Dimmock, D.P.5
Hambuch, T.6
-
87
-
-
33645396945
-
Genetic clonal diversity predicts progression to esophageal adenocarcinoma
-
ng1768 [pii] PubMed PMID: 16565718., Epub 2006/03/28
-
Maley CC, Galipeau PC, Finley JC, Wongsurawat VJ, Li X, Sanchez CA, et al. Genetic clonal diversity predicts progression to esophageal adenocarcinoma. Nat Genet (2006) 38(4):468-73. Epub 2006/03/28. doi: ng1768 [pii]10.1038/ng1768. PubMed PMID: 16565718.
-
(2006)
Nat Genet
, vol.38
, Issue.4
, pp. 468-473
-
-
Maley, C.C.1
Galipeau, P.C.2
Finley, J.C.3
Wongsurawat, V.J.4
Li, X.5
Sanchez, C.A.6
|